388 results

1. pCVSN2c-MCP-oScarlet-KASH-6xMS2 Barcode Library

   Pooled Library

   #227672

   Purpose

   RVdG genome plasmids that carry an error-correctable barcode compatible with 3’ capture single cell or single nuclei RNA sequencing readout. For the production of CVS N2c strain G-deleted rabies virus

   Depositor

   Cathryn Cadwell, Tomasz Nowakowski

   Article

   Shin et al bioRxiv [Preprint]. 2024 Dec 11:2024.10.

   Expression

   Mammalian

   Species

   Synthetic

   Available Since

   Feb. 12, 2025

   Availability

   Academic Institutions and Nonprofits only

2. Mouse Brie kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

   Pooled Library

   #75317

   Purpose

   Mouse sgRNA library in backbone lentiCRISPRv2 targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Available Since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

3. hCRISPRi-v2, Membrane Proteins (h6), top 5 sgRNAs/gene

   Pooled Library

   #83976

   Purpose

   Human CRISPRi Pooled Library targeting membrane proteins

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available Since

   Dec. 14, 2016

   Availability

   Academic Institutions and Nonprofits only

4. Humagne Set C

   Pooled Library

   #172650

   Purpose

   Set C contains best-ranked guides 1 and 4.

   Depositor

   John Doench, David Root

   Article

   DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

   Expression

   Mammalian

   Available Since

   Nov. 10, 2021

   Availability

   Academic Institutions and Nonprofits only

5. p11-3’_8xN_PAM-site1 (RTW554)

   Pooled Library

   #160132

   Purpose

   Plasmid library harboring a randomized 8nt PAM 3’ of target site 1. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 3’ PAMs (e.g. Cas9)

   Depositor

   Keith Joung, Benjamin Kleinstiver

   Article

   Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

   Species

   Synthetic

   Use

   CRISPR

   Available Since

   Feb. 8, 2021

   Availability

   Academic Institutions and Nonprofits only

6. Drosophila_sgRNA_group_2

   Pooled Library

   #134583

   Purpose

   Targets Drosophila orthologs of vertebrate genes that have undergone expansion in the vertebrate line

   Depositor

   Norbert Perrimon

   Article

   Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

   Expression

   Insect

   Species

   Drosophila melanogaster

   Use

   CRISPR

   Available Since

   Feb. 25, 2020

   Availability

   Academic Institutions and Nonprofits only

7. Mouse SLC KO Library

   Pooled Library

   #141436

   Purpose

   Knockout library targeting mouse SLC proteins.

   Depositor

   Giulio Superti-Furga

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available Since

   May 18, 2020

   Availability

   Academic Institutions and Nonprofits only

8. Human DNA Binding Domain-Focused CRISPR Knockout Library

   Pooled Library

   #123334

   Purpose

   Designed for genomic deletion screening of transcription factors by targeting the DNA binding domains.

   Depositor

   Christopher Vakoc

   Article

   Huang et al Genes Dev. 2018 Jul 1;32(13-14):915-928.

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   May 2, 2019

   Availability

   Academic Institutions and Nonprofits only

9. pEPIP_PepTile_40merFragments_65CancerDrivers

   Pooled Library

   #172109

   Purpose

   Lentiviral peptide expression library for overexpression fitness screening

   Depositor

   Prashant Mali

   Article

   Ford et al Cell Syst. 2021 Jul 21;12(7):716-732.e7.

   Use

   Lentiviral

   Available Since

   Oct. 21, 2021

   Availability

   Academic Institutions and Nonprofits only

10. Yeast Inducible CRISPRi Library

    Pooled Library

    #161829

    Purpose

    Inducible genome-wide CRISPRi library targeting S. cerevisiae genes with 6-12 guide RNAs per gene.

    Depositor

    Saeed Tavazoie

    Article

    Momen-Roknabadi et al Commun Biol. 2020 Nov 27;3(1):723. doi:

    Expression

    Yeast

    Species

    Saccharomyces cerevisiae

    Use

    CRISPR

    Available Since

    April 28, 2021

    Availability

    Academic Institutions and Nonprofits only

11. Bassik lab Mouse CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases

    Pooled Library

    #1000000122

    Purpose

    CRISPR gRNA mouse knockout pooled library - Drug targets, kinases, phosphatases

    Depositor

    Michael Bassik

    Available Since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only

12. Drosophila_sgRNA_group_1

    Pooled Library

    #134582

    Purpose

    Targets kinases, phosphatases, and Drosophila orthologs of drug targets

    Depositor

    Norbert Perrimon

    Article

    Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

    Expression

    Insect

    Species

    Drosophila melanogaster

    Use

    CRISPR

    Available Since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

13. mCRISPRi-v2, Stress and Proteostasis (m3), top 5 sgRNAs/gene

    Pooled Library

    #83991

    Purpose

    Mouse CRISPRi Pooled Library targeting stress and proteostasis genes

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available Since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

14. mCRISPRi-v2, genome-wide, top 5 sgRNAs/gene

    Pooled Library

    #83987

    Purpose

    Version 2 of the mouse CRISPRi genome wide library

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Use

    Lentiviral

    Available Since

    Nov. 15, 2016

    Availability

    Academic Institutions and Nonprofits only

15. mCRISPRa-v2, Gene Expression (m5), top 5 sgRNAs/gene

    Pooled Library

    #84002

    Purpose

    Mouse CRISPRa Pooled Library targeting gene expression

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available Since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

16. E.coli_GW-sgRNA_Lib3

    Pooled Library

    #113136

    Purpose

    Genome-wide gRNA library for E. coli, sub3

    Depositor

    Chong Zhang

    Article

    Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

    Expression

    Bacterial

    Available Since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only

17. E.coli_GW-sgRNA_Lib1

    Pooled Library

    #113134

    Purpose

    Genome-wide gRNA library for E. coli, sub1

    Depositor

    Chong Zhang

    Article

    Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

    Expression

    Bacterial

    Available Since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only

18. E.coli_GW-sgRNA_Lib4

    Pooled Library

    #113137

    Purpose

    Genome-wide gRNA library for E. coli, sub4

    Depositor

    Chong Zhang

    Article

    Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

    Expression

    Bacterial

    Available Since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only

19. E.coli_GW-sgRNA_Lib2

    Pooled Library

    #113135

    Purpose

    Genome-wide gRNA library for E. coli, sub2

    Depositor

    Chong Zhang

    Article

    Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

    Expression

    Bacterial

    Available Since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only

20. E.coli_NC_sgRNA_lib

    Pooled Library

    #113146

    Purpose

    Genome-wide gRNA library for E. coli, non-targeting control

    Depositor

    Chong Zhang

    Article

    Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

    Expression

    Bacterial

    Available Since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only