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350 results

Showing: 161 - 180 of 350 results

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Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF), Set A

Pooled Library

#92383

Purpose

CRISPRa

Depositor

John Doench, David Root

Article

Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

July 13, 2018

Availability

Academic Institutions and Nonprofits only
TP53 MITE Library

Pooled Library

#113569

Purpose

Pooled lentiviral plasmid library containing ~8,000 single amino acid substitution and nonsense mutant variants of p53

Depositor

William Hahn, David Root

Article

Giacomelli et al Nat Genet. 2018 Oct;50(10):1381-1387. do

Expression

Mammalian

Species

Homo sapiens

Use

Lentiviral

Available since

Jan. 4, 2019

Availability

Academic Institutions and Nonprofits only
hCRISPRa-v2, Mitochondria, Trafficking, and Motility (h4), top 5 sgRNAs/gene

Pooled Library

#83983

Purpose

Human CRISPRa Pooled Library targeting Mitochondria, Trafficking, and Motility genes

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only
hCRISPRi-v2, Cancer and Apoptosis (h2), top 5 sgRNAs/gene

Pooled Library

#83972

Purpose

Human CRISPRi Pooled Library targeting cancer and apoptosis genes

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Dec. 14, 2016

Availability

Academic Institutions and Nonprofits only
Wei lab paired-guide RNA (pgRNA) CRISPR–Cas9 library for human long non-coding RNAs (lncRNAs)

Pooled Library

#89640

Purpose

Paired sgRNA library containing 12,472 pgRNAs targeting 671 human long non-coding RNAs (lncRNAs)

Depositor

Wensheng Wei

Article

Zhu et al Nat Biotechnol. 2016 Dec;34(12):1279-128

Expression

Mammalian

Use

Lentiviral

Available since

May 17, 2017

Availability

Academic Institutions and Nonprofits only
hCRISPRa-v2, Cancer and Apoptosis (h2), top 5 sgRNAs/gene

Pooled Library

#83981

Purpose

Human CRISPRa Pooled Library targeting cancer and apoptosis genes

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only
pSMAL-CellTag-V3

Pooled Library

#115645

Purpose

Viral barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics

Depositor

Samantha Morris

Article

Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

Has Service

Concentrated Lentiviral Prep

Expression

Mammalian

Species

Synthetic

Use

Lentiviral

Available since

Dec. 5, 2018

Availability

Academic Institutions and Nonprofits only
Human CRISPRi sgRNA library Dolcetto in backbone XPR_050, Set B

Pooled Library

#92386

Purpose

Crispri

Depositor

John Doench, David Root

Article

Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

Has Service

Lentiviral Prep

Use

Lentiviral

Available since

July 13, 2018

Availability

Academic Institutions and Nonprofits only
Sabatini/Lander Lab Activity-Optimized Genome-wide Mouse sgRNA Library in pLenti-sgRNA

Pooled Library

#1000000096

Purpose

CRISPR gRNA knockout pooled library for targeting the mouse genome

Depositor

David Sabatini, Eric Lander

Available since

April 3, 2017

Availability

Academic Institutions and Nonprofits only
psgRNA Library

Pooled Library

#115927

Purpose

Genome-wide knockdown of E. coli genes

Depositor

David Bikard

Article

Cui et al Nat Commun. 2018 May 15;9(1):1912. doi:

Expression

Bacterial

Species

Escherichia coli

Use

CRISPR

Available since

June 6, 2019

Availability

Academic Institutions and Nonprofits only
Human Lentiviral sgRNA Library - Cell Cycle

Pooled Library

#51046

Purpose

Sub-pool of Sabatini/Lander sgRNA library enriched for cell cycle-related targets.

Depositor

David Sabatini, Eric Lander

Article

Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Feb. 7, 2014

Availability

Academic Institutions and Nonprofits only
Humagne Set C

Pooled Library

#172650

Purpose

Set C contains best-ranked guides 1 and 4.

Depositor

John Doench, David Root

Article

DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

Expression

Mammalian

Available since

Nov. 10, 2021

Availability

Academic Institutions and Nonprofits only
Mouse Validation (mVAL) CRISPR Library

Pooled Library

#159391

Purpose

Pooled CRISPR library targets core intrinsic immune evasion genes

Depositor

Jason Moffat

Article

Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available since

Nov. 9, 2020

Availability

Academic Institutions and Nonprofits only
Sabatini/Lander Lab Activity-Optimized Genome-wide Human sgRNA Library in pLenti-sgRNA

Pooled Library

#1000000095

Purpose

CRISPR gRNA knockout pooled library for targeting the human genome

Depositor

David Sabatini, Eric Lander

Available since

April 3, 2017

Availability

Academic Institutions and Nonprofits only
Bassik lab Mouse CRISPR-Cas9 Deletion Library - Gene Expression

Pooled Library

#1000000123

Purpose

CRISPR gRNA mouse knockout pooled library - Gene expression

Depositor

Michael Bassik

Available since

May 23, 2018

Availability

Academic Institutions and Nonprofits only
Human CRISPR Knockout Pooled Library (H3)

Pooled Library

#133914

Purpose

CRISPR gRNA knockout pooled library for targeting the human genome - version H3

Depositor

Xiaole Shirley Liu, Myles Brown

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Jan. 24, 2020

Availability

Academic Institutions and Nonprofits only
Human Lentiviral sgRNA Library - Control

Pooled Library

#51048

Purpose

Sub-pool of Sabatini/Lander sgRNA library enriched for control targets.

Depositor

David Sabatini, Eric Lander

Article

Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Feb. 7, 2014

Availability

Academic Institutions and Nonprofits only
mCRISPRi-v2, Gene Expression (m5), top 5 sgRNAs/gene

Pooled Library

#83993

Purpose

Mouse CRISPRi Pooled Library targeting gene expression

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only
Human Brunello kinome pooled library, guides 5-8 in lentiCRISPRv2 backbone

Pooled Library

#75315

Purpose

Human sgRNA library in backbone lentiCRISPRv2 targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

June 27, 2016

Availability

Academic Institutions and Nonprofits only
hCRISPRi-v2, Stress and Proteostasis (h3), top 5 sgRNAs/gene

Pooled Library

#83973

Purpose

Human CRISPRi Pooled Library targeting stress and proteostasis genes

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Dec. 14, 2016

Availability

Academic Institutions and Nonprofits only

Showing: 161 - 180 of 350 results

Results per page:

Sort results by:

Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF), Set A

TP53 MITE Library

hCRISPRa-v2, Mitochondria, Trafficking, and Motility (h4), top 5 sgRNAs/gene

hCRISPRi-v2, Cancer and Apoptosis (h2), top 5 sgRNAs/gene

Wei lab paired-guide RNA (pgRNA) CRISPR–Cas9 library for human long non-coding RNAs (lncRNAs)

hCRISPRa-v2, Cancer and Apoptosis (h2), top 5 sgRNAs/gene

pSMAL-CellTag-V3

Human CRISPRi sgRNA library Dolcetto in backbone XPR_050, Set B

Sabatini/Lander Lab Activity-Optimized Genome-wide Mouse sgRNA Library in pLenti-sgRNA

psgRNA Library

Human Lentiviral sgRNA Library - Cell Cycle

Humagne Set C

Mouse Validation (mVAL) CRISPR Library

Sabatini/Lander Lab Activity-Optimized Genome-wide Human sgRNA Library in pLenti-sgRNA

Bassik lab Mouse CRISPR-Cas9 Deletion Library - Gene Expression

Human CRISPR Knockout Pooled Library (H3)

Human Lentiviral sgRNA Library - Control

mCRISPRi-v2, Gene Expression (m5), top 5 sgRNAs/gene

Human Brunello kinome pooled library, guides 5-8 in lentiCRISPRv2 backbone

hCRISPRi-v2, Stress and Proteostasis (h3), top 5 sgRNAs/gene

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