Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation.
Horlbeck MA, Gilbert LA, Villalta JE, Adamson B, Pak RA, Chen Y, Fields AP, Park CY, Corn JE, Kampmann M, Weissman JS
Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760.
(Link opens in a new window)
PubMed
(Link opens in a new window)
Article
Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
83969 | hCRISPRi-v2, genome-wide, top 5 sgRNAs/gene | Version 2 of the human CRISPRi genome wide library |
83971 | hCRISPRi-v2, Kinases, Phosphatases, and Drug Targets (h1), top 5 sgRNAs/gene | Human CRISPRi Pooled Library tartgeting kinsases, phosphatases and Drug Targets |
83972 | hCRISPRi-v2, Cancer and Apoptosis (h2), top 5 sgRNAs/gene | Human CRISPRi Pooled Library targeting cancer and apoptosis genes |
83973 | hCRISPRi-v2, Stress and Proteostasis (h3), top 5 sgRNAs/gene | Human CRISPRi Pooled Library targeting stress and proteostasis genes |
83974 | hCRISPRi-v2, Mitochondria, Trafficking, and Motility (h4), top 5 sgRNAs/gene | Human CRISPRi Pooled Library targeting Mitochondria, Trafficking, and Motility genes |
83975 | hCRISPRi-v2, Gene Expression (h5), top 5 sgRNAs/gene | Human CRISPRi Pooled Library targeting gene expression |
83976 | hCRISPRi-v2, Membrane Proteins (h6), top 5 sgRNAs/gene | Human CRISPRi Pooled Library targeting membrane proteins |
83977 | hCRISPRi-v2, Unassigned (h7), top 5 sgRNAs/gene | Human CRISPRi Pooled Library targeting unassigned genes |
83978 | hCRISPRa-v2, genome-wide, top 5 sgRNAs/gene | Version 2 of the human CRISPRa genome wide library |
83980 | hCRISPRa-v2, Kinases, Phosphatases, and Drug Targets (h1), top 5 sgRNAs/gene | Human CRISPRa Pooled Library tartgeting kinsases, phosphatases and Drug Targets |
83981 | hCRISPRa-v2, Cancer and Apoptosis (h2), top 5 sgRNAs/gene | Human CRISPRa Pooled Library targeting cancer and apoptosis genes |
83982 | hCRISPRa-v2, Stress and Proteostasis (h3), top 5 sgRNAs/gene | Human CRISPRa Pooled Library targeting stress and proteostasis genes |
83983 | hCRISPRa-v2, Mitochondria, Trafficking, and Motility (h4), top 5 sgRNAs/gene | Human CRISPRa Pooled Library targeting Mitochondria, Trafficking, and Motility genes |
83984 | hCRISPRa-v2, Gene Expression (h5), top 5 sgRNAs/gene | Human CRISPRa Pooled Library targeting gene expression |
83985 | hCRISPRa-v2, Membrane Proteins (h6), top 5 sgRNAs/gene | Human CRISPRa Pooled Library targeting membrane proteins |
83986 | hCRISPRa-v2, Unassigned (h7), top 5 sgRNAs/gene | Human CRISPRa Pooled Library targeting unassigned genes |
83987 | mCRISPRi-v2, genome-wide, top 5 sgRNAs/gene | Version 2 of the mouse CRISPRi genome wide library |
83989 | mCRISPRi-v2, Kinases, Phosphatases, and Drug Targets (m1), top 5 sgRNAs/gene | Mouse CRISPRi Pooled Library tartgeting kinsases, phosphatases and Drug Targets |
83990 | mCRISPRi-v2, Cancer and Apoptosis (m2), top 5 sgRNAs/gene | Mouse CRISPRi Pooled Library targeting cancer and apoptosis genes |
83991 | mCRISPRi-v2, Stress and Proteostasis (m3), top 5 sgRNAs/gene | Mouse CRISPRi Pooled Library targeting stress and proteostasis genes |
83992 | mCRISPRi-v2, Mitochondria, Trafficking, and Motility (m4), top 5 sgRNAs/gene | Mouse CRISPRi Pooled Library targeting Mitochondria, Trafficking, and Motility genes |
83993 | mCRISPRi-v2, Gene Expression (m5), top 5 sgRNAs/gene | Mouse CRISPRi Pooled Library targeting gene expression |
83994 | mCRISPRi-v2, Membrane Proteins (m6), top 5 sgRNAs/gene | Mouse CRISPRi Pooled Library targeting membrane proteins |
83995 | mCRISPRi-v2, Unassigned (m7), top 5 sgRNAs/gene | Mouse CRISPRi Pooled Library targeting unassigned genes |
83996 | mCRISPRa-v2, genome-wide, top 5 sgRNAs/gene | Version 2 of the mouse CRISPRa genome wide library |
83998 | mCRISPRa-v2, Kinases, Phosphatases, and Drug Targets (m1), top 5 sgRNAs/gene | Mouse CRISPRi Pooled Library tartgeting kinsases, phosphatases and Drug Targets |
83999 | mCRISPRa-v2, Cancer and Apoptosis (m2), top 5 sgRNAs/gene | Mouse CRISPRa Pooled Library targeting cancer and apoptosis genes |
84000 | mCRISPRa-v2, Stress and Proteostasis (m3), top 5 sgRNAs/gene | Mouse CRISPRi Pooled Library targeting stress and proteostasis genes |
84001 | mCRISPRa-v2, Mitochondria, Trafficking, and Motility (m4), top 5 sgRNAs/gene | Mouse CRISPRa Pooled Library targeting Mitochondria, Trafficking, and Motility genes |
84002 | mCRISPRa-v2, Gene Expression (m5), top 5 sgRNAs/gene | Mouse CRISPRa Pooled Library targeting gene expression |
84003 | mCRISPRa-v2, Membrane Proteins (m6), top 5 sgRNAs/gene | Mouse CRISPRa Pooled Library targeting membrane proteins |
84004 | mCRISPRa-v2, Unassigned (m7), top 5 sgRNAs/gene | Mouse CRISPRa Pooled Library targeting unassigned genes |
84832 | pCRISPRia-v2 | CRISPRi/a V2 library parental plasmid |