Addgene

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Humagne Set D

Pooled Library

#172651

Purpose

Set D contains best-ranked guides 2 and 3.

Depositor

John Doench, David Root

Article

DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

Expression

Mammalian

Available since

Nov. 10, 2021

Availability

Academic Institutions and Nonprofits only
mCRISPRa-v2, genome-wide, top 5 sgRNAs/gene

Pooled Library

#83996

Purpose

Version 2 of the mouse CRISPRa genome wide library

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Use

Lentiviral

Available since

Nov. 15, 2016

Availability

Academic Institutions and Nonprofits only
Human Lentiviral sgRNA Library - Ribosomal Proteins

Pooled Library

#51045

Purpose

Sub-pool of Sabatini/Lander sgRNA library enriched for ribosomal gene targets.

Depositor

David Sabatini, Eric Lander

Article

Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Feb. 7, 2014

Availability

Academic Institutions and Nonprofits only
BARBEKO sgRNA library

Pooled Library

#174163

Purpose

iBARed cytosine Base Editing-mediated gene KnockOut (BARBEKO) sgRNA library; This library leverages CRISPR cytosine base editors for genome-scale knockout screens.

Depositor

Wensheng Wei

Article

Xu et al Nat Biotechnol. 2021 Jun 21. pii: 10.103

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Aug. 31, 2021

Availability

Academic Institutions and Nonprofits only
mCRISPRi-v2, Stress and Proteostasis (m3), top 5 sgRNAs/gene

Pooled Library

#83991

Purpose

Mouse CRISPRi Pooled Library targeting stress and proteostasis genes

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only
Sctrans-PP

Pooled Library

#153101

Purpose

CRISPR library targets all non-essential and conditionally essential transporter genes in S. cerevisiae

Depositor

Irina Borodina

Article

Wang et al Metab Eng. 2021 Jan 16. pii: S1096-7176(

Expression

Yeast

Species

Saccharomyces cerevisiae

Use

CRISPR

Available since

Jan. 20, 2021

Availability

Academic Institutions and Nonprofits only
Bassik lab Mouse CRISPR-Cas9 Deletion Library - Trafficking, mitochondrial, motility

Pooled Library

#1000000126

Purpose

CRISPR gRNA mouse knockout pooled library - Trafficking, mitochondrial, and motility

Depositor

Michael Bassik

Available since

May 23, 2018

Availability

Academic Institutions and Nonprofits only
mCRISPRa-v2, Gene Expression (m5), top 5 sgRNAs/gene

Pooled Library

#84002

Purpose

Mouse CRISPRa Pooled Library targeting gene expression

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only
Human CRISPR Poison Exon Knockout Library

Pooled Library

#138084

Purpose

The human pgPoison library induces skipping of “poison” cassette exons and corresponding upstream constitutive exons by targeting 3' splice sites with paired gRNAs (pgRNAs).

Depositor

Robert Bradley

Article

Thomas et al Nat Genet. 2020 Jan;52(1):84-94. doi: 10

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

March 6, 2020

Availability

Academic Institutions and Nonprofits only
Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set B

Pooled Library

#92380

Purpose

CRISPRa

Depositor

John Doench, David Root

Article

Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

Use

Lentiviral

Available since

Aug. 3, 2017

Availability

Academic Institutions and Nonprofits only
CRISPRi non-coding library (CRiNCL) - Common to all 5 cancer cell lines

Pooled Library

#86539

Depositor

Jonathan Weissman

Article

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

Available since

March 8, 2017

Availability

Academic Institutions and Nonprofits only
mCRISPRi-v2, Cancer and Apoptosis (m2), top 5 sgRNAs/gene

Pooled Library

#83990

Purpose

Mouse CRISPRi Pooled Library targeting cancer and apoptosis genes

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only
CRISPRi non-coding library (CRiNCL) - Unique to K562

Pooled Library

#86544

Depositor

Jonathan Weissman

Article

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

Available since

March 8, 2017

Availability

Academic Institutions and Nonprofits only
mCRISPRa-v2, Cancer and Apoptosis (m2), top 5 sgRNAs/gene

Pooled Library

#83999

Purpose

Mouse CRISPRa Pooled Library targeting cancer and apoptosis genes

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only
p11-5’_10xN_PAM-site4 (RTW574)

Pooled Library

#160135

Purpose

Plasmid library harboring a randomized 10nt PAM 5’ of target site 4. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 5’ PAMs (e.g. Cas12a)

Depositor

Keith Joung, Benjamin Kleinstiver

Article

Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

Species

Synthetic

Use

CRISPR

Available since

Feb. 8, 2021

Availability

Academic Institutions and Nonprofits only
MYC-CRISPR

Pooled Library

#173195

Purpose

This pooled lentiviral CRISPR knockout library targets E-boxes genome-wide and can be applied for identification of essential MYC binding sites in a wide range of human cells.

Depositor

Agnieszka Dzikiewicz-Krawczyk

Article

Kazimierska et al Mol Oncol. 2023 Nov;17(11):2295-2313. do

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Aug. 11, 2021

Availability

Academic Institutions and Nonprofits only
mCRISPRi-v2, Mitochondria, Trafficking, and Motility (m4), top 5 sgRNAs/gene

Pooled Library

#83992

Purpose

Mouse CRISPRi Pooled Library targeting Mitochondria, Trafficking, and Motility genes

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only
mCRISPRi-v2, Unassigned (m7), top 5 sgRNAs/gene

Pooled Library

#83995

Purpose

Mouse CRISPRi Pooled Library targeting unassigned genes

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only
pre-associated oBC-minP-GFP-mBC backbone (p043)

Pooled Library

#194098

Purpose

pre-associated oBC-minP-GFP-mBC backbone (p043), can directly be used to deposit library of regulatory elements

Depositor

Jay Shendure

Article

Lalanne et al bioRxiv 2022.12.10.519236

Expression

Bacterial and Mammalian

Use

RNAi

Available since

April 3, 2024

Availability

Academic Institutions and Nonprofits only
hCRISPRa-v2, Stress and Proteostasis (h3), top 5 sgRNAs/gene

Pooled Library

#83982

Purpose

Human CRISPRa Pooled Library targeting stress and proteostasis genes

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only

Showing: 181 - 200 of 350 results

Results per page:

Sort results by:

Humagne Set D

mCRISPRa-v2, genome-wide, top 5 sgRNAs/gene

Human Lentiviral sgRNA Library - Ribosomal Proteins

BARBEKO sgRNA library

mCRISPRi-v2, Stress and Proteostasis (m3), top 5 sgRNAs/gene

Sctrans-PP

Bassik lab Mouse CRISPR-Cas9 Deletion Library - Trafficking, mitochondrial, motility

mCRISPRa-v2, Gene Expression (m5), top 5 sgRNAs/gene

Human CRISPR Poison Exon Knockout Library

Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set B

CRISPRi non-coding library (CRiNCL) - Common to all 5 cancer cell lines

mCRISPRi-v2, Cancer and Apoptosis (m2), top 5 sgRNAs/gene

CRISPRi non-coding library (CRiNCL) - Unique to K562

mCRISPRa-v2, Cancer and Apoptosis (m2), top 5 sgRNAs/gene

p11-5’_10xN_PAM-site4 (RTW574)

MYC-CRISPR

mCRISPRi-v2, Mitochondria, Trafficking, and Motility (m4), top 5 sgRNAs/gene

mCRISPRi-v2, Unassigned (m7), top 5 sgRNAs/gene

pre-associated oBC-minP-GFP-mBC backbone (p043)

hCRISPRa-v2, Stress and Proteostasis (h3), top 5 sgRNAs/gene

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