Supporting Rare Disease Research with the 2020 BeHEARD Awards
Type
Blog Post
Published
Sept. 8, 2020, 2 p.m.
...resulting in the activation of keratinocytes, which release inflammatory mediators that trigger the activation...pharmaceutical interventions that would inhibit IL-36 release,” says Dr. Mark Mellett, a senior researcher at...autoinflammatory loop: keratinocytes both respond to and release IL-36 cytokines. Keratinocytes are the main source...what molecules or proteins are involved in IL-36 release in keratinocytes,” says Mellett. This would help...Bicuspid aortic valve (an aortic valve that has two leaflets, instead of three) and acute aortic dissections...that this is abnormally deregulated in TS and can lead to cardiac developmental defects.
Eight genes from... codes for G𝛃1 subunits of G protein complexes, lead to a rare type of developmental delay, and is characterized...