Addgene

350 results

Showing: 101 - 120 of 350 results

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mCRISPRi-v2, Kinases, Phosphatases, and Drug Targets (m1), top 5 sgRNAs/gene

Pooled Library

#83989

Purpose

Mouse CRISPRi Pooled Library tartgeting kinsases, phosphatases and Drug Targets

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only
Mouse sgRNA library Gouda in pRDA_118 backbone

Pooled Library

#136987

Purpose

Expresses sgRNAs targeting mouse genes

Depositor

John Doench

Article

DeWeirdt et al Nat Commun. 2020 Feb 6;11(1):752. doi: 1

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available since

Feb. 24, 2020

Availability

Academic Institutions and Nonprofits only
Sabatini/Lander Lab Activity-Optimized Genome-wide Human sgRNA Library in lentiCRISPR v1

Pooled Library

#1000000100

Purpose

CRISPR gRNA knockout pooled library (version 1) for targeting the human genome

Depositor

David Sabatini, Eric Lander

Available since

April 3, 2017

Availability

Academic Institutions and Nonprofits only
Human Brunello kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

Pooled Library

#75314

Purpose

Human sgRNA library in backbone lentiCRISPRv2 targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

June 27, 2016

Availability

Academic Institutions and Nonprofits only
sgRNA pool for Streptococcus pneumoniae

Pooled Library

#170432

Purpose

CRISPR library targeting S. pneumoniae D39V

Depositor

Jan-Willem Veening

Article

Liu et al Cell Host Microbe. 2021 Jan 13;29(1):107

Expression

Bacterial

Use

CRISPR

Available since

Aug. 31, 2021

Availability

Academic Institutions and Nonprofits only
Human Brunello kinome pooled library, guides 1-8 in lentiGuide-Puro backbone

Pooled Library

#1000000082

Purpose

CRISPR gRNA knockout pooled library for targeting the human kinome

Depositor

John Doench, David Root

Available since

June 27, 2016

Availability

Academic Institutions and Nonprofits only
Bassik lab Mouse CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases

Pooled Library

#1000000122

Purpose

CRISPR gRNA mouse knockout pooled library - Drug targets, kinases, phosphatases

Depositor

Michael Bassik

Available since

May 23, 2018

Availability

Academic Institutions and Nonprofits only
Human Kinase Domain-Focused CRISPR Knockout Library

Pooled Library

#117725

Purpose

gRNAs targeting the kinase domain of human protein kinases

Depositor

Christopher Vakoc

Article

Tarumoto et al Mol Cell. 2018 Feb 28. pii: S1097-2765(1

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Jan. 4, 2019

Availability

Academic Institutions and Nonprofits only
mCRISPRa-v2, Membrane Proteins (m6), top 5 sgRNAs/gene

Pooled Library

#84003

Purpose

Mouse CRISPRa Pooled Library targeting membrane proteins

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only
pLCKO2::TKOv3

Pooled Library

#125517

Purpose

Human CRISPR lentiviral library containing 70,948 guides (4-5 guides/gene) targeting 18,053 human protein-coding genes, in a non-Cas9 containing backbone

Depositor

Jason Moffat

Article

Mair et al Cell Rep. 2019 Apr 9;27(2):599-615.e12.

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Aug. 1, 2019

Availability

Academic Institutions and Nonprofits only
hCRISPRa-v2, Gene Expression (h5), top 5 sgRNAs/gene

Pooled Library

#83984

Purpose

Human CRISPRa Pooled Library targeting gene expression

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only
Bassik lab Human CRISPR-Cas9 Deletion Library - Trafficking, mitochondrial, motility

Pooled Library

#101931

Purpose

Bassik lab Human CRISPR-Cas9 Deletion Library - Trafficking, mitochondrial, motility. Coexpresses mCherry.

Depositor

Michael Bassik

Article

Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

Expression

Mammalian

Use

CRISPR

Available since

May 23, 2018

Availability

Academic Institutions and Nonprofits only
Bassik lab Human CRISPR-Cas9 Deletion Library - Apoptosis and cancer

Pooled Library

#101926

Purpose

Bassik lab Human CRISPR-Cas9 Deletion Library - Apoptosis and cancer. Coexpresses mCherry.

Depositor

Michael Bassik

Article

Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

Expression

Mammalian

Use

CRISPR

Available since

May 23, 2018

Availability

Academic Institutions and Nonprofits only
RLC11

Pooled Library

#163955

Purpose

RLC11 pooled library

Depositor

Jeremy Rock

Article

Bosch et al Cell. 2021 Jul 16. pii: S0092-8674(21)00

Expression

Bacterial

Use

CRISPR

Available since

Oct. 1, 2021

Availability

Academic Institutions and Nonprofits only
Mouse Brie kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

Pooled Library

#75317

Purpose

Mouse sgRNA library in backbone lentiCRISPRv2 targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Available since

June 27, 2016

Availability

Academic Institutions and Nonprofits only
Yeast Inducible CRISPRi Library

Pooled Library

#161829

Purpose

ATc inducbile yeast CRISPRi library

Depositor

Saeed Tavazoie

Article

Momen-Roknabadi et al Commun Biol. 2020 Nov 27;3(1):723. doi:

Expression

Yeast

Species

Saccharomyces cerevisiae

Use

CRISPR

Available since

April 28, 2021

Availability

Academic Institutions and Nonprofits only
hCRISPRi-v2, Gene Expression (h5), top 5 sgRNAs/gene

Pooled Library

#83975

Purpose

Human CRISPRi Pooled Library targeting gene expression

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Dec. 14, 2016

Availability

Academic Institutions and Nonprofits only
Human messenger-RBP sgRNA library

Pooled Library

#168791

Purpose

CRISPR library targets sub-pool of human mRNA binding proteins

Depositor

Martin Turner

Article

Turner et al CRISPR J. 2021 Jun;4(3):427-437. doi: 10

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

July 30, 2021

Availability

Academic Institutions and Nonprofits only
Pan-Druggable Cancer Library

Pooled Library

#182133

Purpose

All-in-one CRISPR/Cas system with 74 individual elements. 63 elements target cancer-related genes with FDA-approved drug treatments, and 3 elements target key medulloblastoma driver genes.

Depositor

Prashant Mali

Article

Hu et al Biomaterials. 2022 Jan;280:121276. doi:

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Aug. 26, 2022

Availability

Academic Institutions and Nonprofits only
mCRISPRi-v2, Membrane Proteins (m6), top 5 sgRNAs/gene

Pooled Library

#83994

Purpose

Mouse CRISPRi Pooled Library targeting membrane proteins

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only

Showing: 101 - 120 of 350 results

Results per page:

Sort results by:

mCRISPRi-v2, Kinases, Phosphatases, and Drug Targets (m1), top 5 sgRNAs/gene

Mouse sgRNA library Gouda in pRDA_118 backbone

Sabatini/Lander Lab Activity-Optimized Genome-wide Human sgRNA Library in lentiCRISPR v1

Human Brunello kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

sgRNA pool for Streptococcus pneumoniae

Human Brunello kinome pooled library, guides 1-8 in lentiGuide-Puro backbone

Bassik lab Mouse CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases

Human Kinase Domain-Focused CRISPR Knockout Library

mCRISPRa-v2, Membrane Proteins (m6), top 5 sgRNAs/gene

pLCKO2::TKOv3

hCRISPRa-v2, Gene Expression (h5), top 5 sgRNAs/gene

Bassik lab Human CRISPR-Cas9 Deletion Library - Trafficking, mitochondrial, motility

Bassik lab Human CRISPR-Cas9 Deletion Library - Apoptosis and cancer

RLC11

Mouse Brie kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

Yeast Inducible CRISPRi Library

hCRISPRi-v2, Gene Expression (h5), top 5 sgRNAs/gene

Human messenger-RBP sgRNA library

Pan-Druggable Cancer Library

mCRISPRi-v2, Membrane Proteins (m6), top 5 sgRNAs/gene

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