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Plasmid#193350PurposeRetroviral vector expressing human SOX2-17 chimeric transcription factor (super-SOX)DepositorInsertSOX2-17 (SOX2 Human)
UseRetroviralTagsExpressionMammalianMutationSOX2-17 is engineered highly cooperative chimeric…Promoter5'LTRAvailable sinceDec. 15, 2022AvailabilityAcademic Institutions and Nonprofits only -
pCXLE-Sox2-T2A-Klf4-E2A-Myc
Plasmid#210018Purposeepisomal SKM (expressing mouse Sox2 + Klf4 + Myc) for integration-free naïve resetDepositorUseTagsExpressionMammalianMutationPromoterCAGAvailable sinceDec. 14, 2023AvailabilityAcademic Institutions and Nonprofits only -
pAAV-Tnnt2-GFP-LA
Plasmid#206198PurposeExpresses GFP-tagged Lamin-A specifically in cardiomyocytes by the Tnnt2 promoterDepositorInsertLmna (LMNA Human)
UseAAVTagsGFPExpressionMutationPromoterTnnt2Available sinceAug. 23, 2024AvailabilityAcademic Institutions and Nonprofits only -
pCXLE-Sox2-17-T2A-Klf4-E2A-Myc
Plasmid#210016Purposeepisomal S*KM (expressing mouse super-Sox + Klf4 + Myc) for integration-free naïve resetDepositorUseTagsExpressionMammalianMutationSox2-17 is engineered highly cooperative chimeric…PromoterCAGAvailable sinceDec. 14, 2023AvailabilityAcademic Institutions and Nonprofits only -
pCXLE-Sox2AV-T2A-Klf4-E2A-Myc
Plasmid#210017Purposeepisomal SKM (expressing mouse Sox2-A61V + Klf4 + Myc) for high-quality integration-free naïve reset; best for rodents and primates (including human).DepositorUseTagsExpressionMammalianMutationSox2A61V is a point mutant of Sox2 that enhances …PromoterCAGAvailable sinceDec. 14, 2023AvailabilityAcademic Institutions and Nonprofits only -
pCXLE-SOX2-p2a-KLF4
Plasmid#193292Purposeepisomal hSK (expressing human SOX2 + KLF4)DepositorUseTagsExpressionMammalianMutationF2A of original pCXLE-SK vector was replaced with…PromoterCAGAvailable sinceDec. 14, 2022AvailabilityAcademic Institutions and Nonprofits only -
pCXLE-mCherry-t2a-SOX2-p2a-KLF4
Plasmid#193296Purposeepisomal mCherry-hSK (expressing mCherry + human SOX2 + KLF4)DepositorUseTagsExpressionMammalianMutationPromoterCAGAvailable sinceDec. 13, 2022AvailabilityAcademic Institutions and Nonprofits only -
pHAGE2-TetOminiCMV-Sox2-17-t2a-Klf4
Plasmid#193348PurposetetO-S*K (Dox-inducible reprogramming lentiviral vector expressing mouse super-Sox + Klf4)DepositorUseLentiviralTagsExpressionMammalianMutationSox2-17 is engineered highly cooperative chimeric…PromoterTetO mini CMVAvailable sinceDec. 14, 2022AvailabilityAcademic Institutions and Nonprofits only -
RB1-TP53-LRG-GFP
Plasmid#225876PurposeGuides targeting TP53 and RB1DepositorUseCRISPR and LentiviralTagsExpressionMutationPromoterU6Available sinceOct. 15, 2024AvailabilityAcademic Institutions and Nonprofits only -
pHAGE2-TetOminiCMV-Klf4-IRES-Sox2-17
Plasmid#193299PurposetetO-KS* (Dox-inducible reprogramming lentiviral vector expressing mouse Klf4 + super-Sox)DepositorUseLentiviralTagsExpressionMammalianMutationSox2-17 is engineered highly cooperative chimeric…PromoterTetO mini CMVAvailable sinceDec. 14, 2022AvailabilityAcademic Institutions and Nonprofits only -
pCXLE-SOX2AV-p2a-KLF4
Plasmid#193291Purposeepisomal expressing human SOX2A61V + KLF4DepositorUseTagsExpressionMammalianMutationSOX2A61V is a highly cooperative point mutant of …PromoterCAGAvailable sinceDec. 14, 2022AvailabilityAcademic Institutions and Nonprofits only -
pCXLE-mCherry-t2a-SOX2AV-p2a-KLF4
Plasmid#193295Purposeepisomal vector expressing mCherry + human SOX2A61V + KLF4DepositorUseTagsExpressionMammalianMutationSOX2A61V is a highly cooperative point mutant of …PromoterCAGAvailable sinceDec. 13, 2022AvailabilityAcademic Institutions and Nonprofits only -
pCXLE-SOX2-17-p2a-KLF4
Plasmid#193290Purposeepisomal hS*K (expressing human super-SOX + KLF4) for enhanced generation of intergration-free iPSCs or for integration-free naïve conversionDepositorUseTagsExpressionMammalianMutationSOX2-17 is engineered highly cooperative chimeric…PromoterCAGAvailable sinceDec. 13, 2022AvailabilityAcademic Institutions and Nonprofits only -
pCXLE-Oct4-p2a-Klf4-IRES-Sox2-17
Plasmid#193298Purposeepisomal OKS* (expressing mouse Oct4 + Klf4 + super-Sox) for generation of integration-free iPSCsDepositorUseTagsExpressionMammalianMutationSox2-17 is engineered highly cooperative chimeric…PromoterCAGAvailable sinceDec. 15, 2022AvailabilityAcademic Institutions and Nonprofits only -
pCXLE-mCherry-t2a-SOX2-17-p2a-KLF4
Plasmid#193294Purposeepisomal mCherry-hS*K (expressing mCherry + human super-SOX + KLF4) for integration-free naïve conversionDepositorUseTagsExpressionMammalianMutationSOX2-17 is engineered highly cooperative chimeric…PromoterCAGAvailable sinceDec. 13, 2022AvailabilityAcademic Institutions and Nonprofits only -
pHAGE2-TetOminiCMV-Sox2-17-t2a-Klf4-e2a-Myc
Plasmid#193349PurposetetO-S*KM (Dox-inducible reprogramming lentiviral vector expressing mouse super-Sox + Klf4 + cMyc)DepositorUseLentiviralTagsExpressionMammalianMutationSox2-17 is engineered highly cooperative chimeric…PromoterTetO mini CMVAvailable sinceJan. 3, 2023AvailabilityAcademic Institutions and Nonprofits only -
pHAGE2-TetOminiCMV-Oct4-P2A-Klf4-IRES-Sox2-17
Plasmid#210020PurposetetO-OKS* (Dox-inducible reprogramming lentiviral vector expressing mouse Oct4 + Klf4 + super-Sox)DepositorUseLentiviralTagsExpressionMammalianMutationPromoterTetO-mini-CMVAvailable sinceNov. 21, 2023AvailabilityAcademic Institutions and Nonprofits only -
pHAGE2-TetOminiCMV-Oct4-P2A-Klf4-IRES-Sox2
Plasmid#210019PurposetetO-OKS (Dox-inducible reprogramming lentiviral vector expressing mouse Oct4 + Klf4 + Sox2)DepositorUseLentiviralTagsExpressionMammalianMutationPromoterTetO-mini-CMVAvailable sinceNov. 21, 2023AvailabilityAcademic Institutions and Nonprofits only -
C99m
Plasmid#121003PurposeMoClo golden gate assembly CD part for codon-optimized mScarlet-I (fast-folding mScarlet variant, codon-optimized for E. coli; see https://www.fpbase.org/protein/mscarlet-i/).DepositorInsertmScarlet-I codon optimized
UseSynthetic BiologyTagsExpressionMutationPromoterAvailable sinceDec. 4, 2019AvailabilityAcademic Institutions and Nonprofits only -
pHAGE2-TetOminiCMV-Oct4-p2a-Sox2-17-t2a-Klf4-e2a-cMyc
Plasmid#193346PurposetetO-OS*KM (Dox-inducible reprogramming lentiviral vector expressing mouse Oct4 + super-Sox + Klf4 + cMyc)DepositorUseLentiviralTagsExpressionMammalianMutationSox2-17 is engineered highly cooperative chimeric…PromoterTetO mini CMVAvailable sinceFeb. 13, 2023AvailabilityAcademic Institutions and Nonprofits only