Purpose
Expresses Cre recombinase and Renilla luciferase from the EFS promoter and three U6-driven sgRNAs targeting Kras, p53, and Lkb1. Contains KrasG12D HDR donor. AAV backbone.
Inserts
sgRNA
Renilla luciferase
Cre recombinase
KrasG12D HDR donor (
Kras Mouse)
Use
AAV, CRISPR, Cre/Lox, and Mouse Targeting
Promoter
EFS, No promoter, and U6
Available Since
Oct. 9, 2014
Availability
Academic Institutions and Nonprofits only