CRISPR Guide
Type
Guide
...enzymes, the Cascade-Cas3 system has been co-opted for use in eukaryotic cells . The Cascade complex is ...separate Cas enzymes that form a complex called Cascade (see Cas3 for more details), while type V-K systems... by Cas9 systems. Cas3 must be paired with the Cascade ( C RISPR- as sociated c omplex for a ntiviral ...de fense) complex to initiate DNA degradation. Cascade is made of five proteins: Cas8 (Cse1), Cas11 (Cse2...Overview of editing with Cas3 Browse Plasmids: Cascade-Cas3 Want more information on the wide variety ...nucleases like Cas9 and Cas12a (also known as Cpf1) Cascade C RISPR- as sociated c omplex for a ntiviral de...Lewis, J. D., & Bondy-Denomy, J. (2020). A compact Cascade–Cas3 system for targeted genome engineering. Nature...