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Addgene
Showing: 1 - 19 of 19 results
  1. Genetic Code Expansion

    Type
    Collection
    ...Code Expansion Genetic Code Expansion You may also like... GCE4All: Making Genetic Code Expansion Accessible...Addgene's guide to plasmids and strains useful for expanding the genetic code in bacteria and mammalian cells.... Yet in the past two decades, biologists have expanded the genetic code by redirecting specific codons...amino acids beyond the 20 standard amino acids. Expanding the Genetic Code In protein translation, an aminoacyl-tRNA...incorporated into the growing peptide chain. To expand the genetic code, modified tRNAs, codons, and tRNA... the existing protein translation machinery. To expand the genetic code, 4 major changes to the standard...stimuli, such as light. On a broader scale, the expanded genetic code can help us understand and evolve...
  2. TALENs for Endogenous Human Genes

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    Collection
    ...TCTGGATCGCGGAGGGAAtgccccggagggcggaGAACTGGGACGAGGCCGA XPA TAL2458 & TAL2459 TGGGCCAGAGATGGCGGCggccgacggggctttgCCGGAGGCGGCGGCTTTA...
  3. p53 Pathway

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    ...The list of p53 transcriptional targets is ever-expanding; the best-characterized effects of p53 are in ... have been characterized as gain-of-function, expanding the mechanisms by which mutant p53 is known to...Oct;9(10):701-13. PubMed PMID: 19693097 . The expanding universe of p53 targets. Menendez D, Inga A, Resnick...
  4. Fluorescent Protein Guide: Biosensors

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    Collection
    ...genetically encoded Calcium indicators (GECOs) An Expanded Palette of Genetically Encoded Ca2+ Indicators...Genetically-encoded yellow fluorescent cAMP indicator with an expanded dynamic range for dual-color imaging. PLoS One...(cGull) Generation of a cGMP Indicator with an Expanded Dynamic Range by Optimization of Amino Acid Linkers...encoded dopamine sensor YdLight1 and RdLight1 An expanded palette of dopamine sensors for multiplex imaging...
  5. Rinehart Lab Phosphoprotein Reagents

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    Collection
    ...protein function and signaling networks continues to expand. The Rinehart and Söll labs at Yale University ...691.3 KB Original Kit (ca. 2011) Described in: Expanding the genetic code of Escherichia coli with phosphoserine...
  6. CRISPR Guide

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    Collection
    ...effects xCas9 3.7 - mutations in multiple domains to expand PAM recognition, increase specificity, and decrease...recognizes NNTA, a PAM sequence often found in plants, expanding the targeting range for plant genome engineering...cleave ssDNA non-specifically. Cas12a also has an expanded targeting range to AT-rich regions, as it recognizes.... (2018). Engineered CRISPR-Cas9 nuclease with expanded targeting space. Science , 361 (6408), 1259–1262...
  7. Plasmid Collections

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    Collection
    ...Expression Systems Empty Backbones Genetic Code Expansion Immunology Mammalian RNAi Microbiology Plant Expression...
  8. Brzezinski Lab CRISPR Collection

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    Collection
    ...several modifications to the the px458 plasmid to expand its usefulness for the lab's gene regulation and...
  9. Brain Armamentarium

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    Collection
    ...access to many different brain cell types. The expanded collection of Armamentarium tools will aid neuroscientists...
  10. COVID-19 Resources

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    ... global research community is moving quickly to expand the knowledge and understanding of COVID-19 and...
  11. CRISPR References and Information

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    ...nuclease sites, this tool from the Joung Lab has been expanded to identify potential DNA target sites for TALEs...
  12. Deisseroth INTRSECT Collection

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    ...Flp, or Flp NOT Cre. B) This strategy has been expanded to incorporate VCre in order to enable three-feature...
  13. Plasmids for Stem Cell Research

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    ...factor-mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells...
  14. Immunology Research Plasmids and Resources

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    Collection
    ...course of an infection, adaptive immune cells will expand and give rise to memory cells that can recognize...of a high avidity BCR through repeat cycles of expansion. Chemokines Chemokines, or chemotactic cytokines...of a high avidity BCR through repeat cycles of expansion. Symbol Name Synonyms AKT1 v-akt murine thymoma...
  15. Validated gRNA Sequences

    Type
    Collection
    ...gRNA sequence spreadsheet". Thanks for helping us expand and improve our resources! Download validated gRNA...
Showing: 1 - 19 of 19 results