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  1. Immunology Research Plasmids and Resources

    Type
    Collection
    ... alpha (TNF superfamily, member 1) LT, TNFB, TNFSF1 LTB lymphotoxin beta (TNF superfamily, member 3) TNFC...receptor superfamily, member 17 BCM, BCMA, CD269 TNFRSF18 tumor necrosis factor receptor superfamily, member...receptor superfamily, member 8 CD30, D1S166E, Ki-1 TNFRSF9 tumor necrosis factor receptor superfamily, member...AEP, LGMN1, PRSC1 LTA lymphotoxin alpha (TNF superfamily, member 1) LT, TNFB, TNFSF1 MICA MHC class I ...molecule 8D6, 8D6A CD40 CD40 molecule, TNF receptor superfamily member 5 Bp50, CDW40, MGC9013, TNFRSF5, p50 CD40LG...

  2. Resolute Plasmid Collection

    Type
    Collection
    ...agreement No 777372. This Joint Undertaking receives support from the European Union's Horizon 2020 research...Description Human SLC Activation Library 132561 Superti-Furga CRISPR activation library targeting human...SLC proteins. Human SLC Knockout Library 132552 Superti-Furga CRISPR knockout library targeting human SLC...SLC proteins. Mouse SLC Knockout Library 141436 Superti-Furga CRISPR knockout library targeting mouse SLC...proteins. Human SLC Overexpression Library 213694 Superti-Furga Inducible barcoded overexpression library...Transporter Knockout Libraries 213695 221409 221410 Superti-Furga CRISPR knockout library targeting human transmembrane...

  3. CRISPR References and Information

    Type
    Collection
    ...sequence and checks for off-target binding. Currently supports: Drosophila, Arabidopsis, zebrafish, C. elegans...regulation (repression and activation). Genome support for bacteria ( E. coli, B. subtilis ), yeast ( ... or a sequence text file you upload. Currently supports: Human, mouse, rat, marmoset, pig, chicken, frog...thermophilus or N. meningitidis Cas9 PAMs. Currently supports: mouse and human. CRISPR Optimal Target Finder...sequence and checks for off-target binding. Currently supports over 20 model and non-model invertebrate species...

  4. Arf GTPase Family

    Type
    Collection
    ... Plasmid Collections ARF Superfamily Plasmids for ARF Superfamily Research You may also like... ...members of the RAS superfamily, though recently have been argued to form their own superfamily (Klinger, et ... GTPase signaling activity. Locations of ARF Superfamily members. Figure from Szutl, et al 2019 PMID: ...: 31084567 . More information about ARF Superfamily members can be found in: ARF GTPases and their GEFs...

  5. p53 Pathway

    Type
    Collection
    ...pathway. p53 is a transcription factor and tumor suppressor activated by cellular stress....Background p53 is a transcription factor and tumor suppressor activated by cellular stresses like DNA damage...the p53 gene causes a large reduction in tumor suppression activity, leading to the development of tumors...Cytochrome c DR5 Tumor necrosis factor receptor superfamily, member 10b E2F-1 E2F transcription factor 1 ...Unravelling mechanisms of p53-mediated tumour suppression. Bieging KT, Mello SS, Attardi LD. Nat Rev Cancer...

  6. CRISPR Pooled gRNA Libraries

    Type
    Collection
    ...Activation Human Superti-Furga 3rd 6 3,342 Human SLC Knockout Library 132552 Knockout Human Superti-Furga 3rd... Libraries 213695 221409 221410 Knockout Human Superti-Furga 3rd Varies Varies Human Transcription Factor...Mouse SLC Knockout Library 141436 Knockout Mouse Superti-Furga 3rd 6 2,384 Mouse Toronto KnockOut (mTKO)...Inhibition Mouse Qi 2nd Varies 93,107 Mouse Tumor Suppressor Gene CRISPR Knockout Library 113584 (EFS) 113585...

  7. New England Biolabs Cell-Imaging Plasmid Collection

    Type
    Collection
    ...Cell-Imaging Plasmid Collection Technology Plasmids Supplemental Information New England Biolabs offers non-toxic...MCP-tag Control for cell surface localization Supplemental Information SNAP and CLIP tags SNAP and CLIP...purchasing coenzyme A disodium salt from a commercial supplier and conjugating it to the label of their choice...

  8. mTOR Pathway

    Type
    Collection
    ...commonly dysregulated in cancer. Loss of the tumor suppressor p53 also promotes aberrant mTORC1 activity, and...growth and proliferation, including an abundant supply of macromolecules and energy, as well as the presence...Tuberous sclerosis VHL Von Hippel-Lindau tumor suppressor Return to top mTORC2 Complex Symbol Name AKT ...

  9. Genetic Code Expansion

    Type
    Collection
    ...azidonorleucine (Anl) Mammalian ATG David Tirrell 91705 pSupAR-MbPylRS(DiZPK) PylRS M. barkeri photocrosslinkers...jannaschii acridone Bacterial TAG Ryan Mehl 197930 pSUP-(2xCouRS-tRNAopt) 7-HCou Aminoacyl (7-hydroxy-4-... out, tyrTV gene replaced by tRNA variant that suppress the TAG nonsense codon, and tyrU gene replaced...tyrTV and tyrU genes replaced by tRNA variant that suppress the TAG nonsense codon). Expresses archaeal MjTyrRS...

  10. Fluorescent Protein Guide: Biosensors

    Type
    Collection
    ...:547-63. Sergio Grinstein pH Superfolder pHluorin pH sensor A superfolder variant of pH-sensitive pHluorin...pHluorin-mKate2-hLC3 (PK-hLC3) for monitoring autophagy A Super-Ecliptic, pHluorin-mKate2, Tandem Fluorescent Protein-Tagged...2017 Mar 13. Katharina Gaus Endo/Exocytosis Superecliptic pHluorin fused to glutamate receptor Glutamate...Neurosci. 2015 Nov 9. Christian Rosenmund pH Superecliptic pHluorin pH sensor Amiloride inhibits macropinocytosis...

  11. Brain Initiative Collection

    Type
    Collection
    ...and antibodies created with support from the BRAIN Initiative below. Support has been identified by depositors...The BRAIN Initiative supports the development of biomolecular tools for neuroscience research. Browse... prevent brain disorders. The BRAIN Initiative supports the development of a diverse portfolio of biomolecular...

  12. Rinehart Lab Phosphoprotein Reagents

    Type
    Collection
    ...phosphoserine using SepOTSλ ( 68292 ) or serine using supD tRNA ( 68307 ) at the central position. Introducing...phosphosite library can also be synthesized using supD tRNA ( 68307 ) to generate the phosphosites with....Δserb.Amp S Plasmid 68292 SepOTSλ Plasmid 68307 SupD Plasmid 34623 SepOTSα SepRS/EF-Sep ( aka. pKD-SepRS-EFSep...

  13. Neurodegeneration Research Collection

    Type
    Collection
    ...BRAIN Initiative Collection The BRAIN Initiative supports the development of a diverse portfolio of biomolecular...This collection highlights plasmids created with support from the BRAIN Initiative. Jackson Laboratory (...a new window) . This resource was created with support from the Chan Zuckerberg Initiative (Link opens...

  14. All Antibodies

    Type
    Collection
    ...on sequence homology with the antigen. Addgene supplies a list of recommended applications based on our...our resources! Acknowledgments This project is supported by a NIH BRAIN Initiative grant (U24NS119916)....

  15. DNA Service - Cloning Grade DNA

    Type
    Collection
    ...Where can I find cloning resources or scientific support? Please see our Addgene Protocols for resources... may find helpful. Our Scientific and Customer Support Teams are also available to provide assistance ...

  16. Addgene Packaged on Request: Scope of Service

    Type
    Collection
    ...titer expectations communicated by email will supersede the general guarantees above. We will have our...timing expectations communicated by email will supersede the general estimated turnaround time above. After...

  17. Open Enzyme Collection

    Type
    Collection
    ...bacteria. This can help reduce lab costs and overcome supply chain issues, particularly in areas of the world...165562 pOpen-Pwopol Pwo DNA Polymerase 165563 pOpen-BsupolLF Bsu DNA Polymerase I, Large Fragment 165570 pOpen-P45...

  18. Cre-lox system

    Type
    Collection
    ...85040 pK170.AAV-TRE-Cre-WPRE (Supernova) TRE-Cre based Supernova TRE AAV Iwasato 85577 pTC-CMV-Tet... pET-(-30)GFP-9xGGS-Cre-6xHis Cre fused to supernegatively charged GFP variant T7 Bacterial Liu 62657 ...

  19. Ras Pathway

    Type
    Collection
    ...CNKSR CNKSR1 CNKSR2 Connector enhancer of kinase suppressor of Ras CYTH2 Cytohesin 2 DUSP DUSP1 DUSP2 DUSP3...substrate JUN Jun proto-oncogene KSR KSR1 KSR2 Kinase suppressor of ras MDM2 MDM2 proto-oncogene MEK MAP2K1 MAP2K2...

  20. Genomic Deletions in Mammalian Cell Lines

    Type
    Collection
    ...culture medium in all steps consists of DMEM supplemented with 2% penicillin/ streptomycin and 1% L-glutamine...Centrifuge PCR plate at 400 x g for 5 min and remove supernatant by flicking the PCR plate over a sink. Add 50...
Showing: 1 - 20 of 50 results