...Xie N/A N/A 395 CRISPRa Discontinued Activation Human Weissman 3rd 10 198,810 CRISPRa-v2 83978 1000000091...Activation Human Weissman 3rd 5 10 104,540 209,080 CRISPRa-v2 83996 1000000093 Activation Mouse Weissman 3rd...Inhibition Human Weissman 3rd 6 Varies Dual sgRNA CRISPRa Libraries 187249 — 187251 1000000193 Activation... Human Sabatini and Lander 3rd 10 Varies FNLCR CRISPRa Cell Surface Libraries 207471 1000000228 Activation....S. Liu 3rd 5 5 10 49,252 Human Metabolic Gene CRISPRa sgRNA Library 187080 Activation Human Birsoy 3rd...3rd Varies 32,460 Mouse Metabolic Gene CRISPRa sgRNA Library 187081 Activation Mouse Birsoy 3rd Varies...Gouda) 136987 Knockout Mouse Doench 3rd 2 44,155 hCRISPRa-v2 subpooled libraries 83980 — 83986 Activation...

...92379 Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set A Human CRISPRa sgRNA activation...

...dCas9 alone for mammalian cell lines. Activate (CRISPRa) Increase expression of an endogenous gene(s) without...

...regulates mitosis. Nat Commun. 2016 Mar 7;7:10869. Hu CRISPRa Human CRISPR activator system for reprogramming...

...CRISPR interference, or CRISPRi) or activation (CRISPRa) of downstream target genes can be achieved by ...bacterial genomic region used in pathogen defense CRISPRa CRISPR Activation; using a dCas9 or dCas9-activator...protein-interacting RNA aptamers, such as in the CRISPRainbow kit . Using multiple copies of the aptamer improves... loci with dCas9 and engineered sgRNAs using CRISPRainbow. Nature Biotechnology . 34 (5), 528–530. PMID...

...produce fluorescence at a target region, as in the CRISPRainbow kit. Plasmid Gene/Insert Promoter Selectable...

... loci with dCas9 and engineered sgRNAs using CRISPRainbow. Nat Biotechnol . . PMID: 27088723 Makarova ...