Skip to main content
Addgene
Showing: 21 - 40 of 41 results

  1. Another Pathway into Cells: iTOP

    Type
    Blog Post
    Published
    June 23, 2015, 8:37 p.m.
    ...cell editing. The small molecule NSDB and Na+ hypertonicity are key elements of iTOP. iTOP can be used to...

  4. Antibodies 101: Secondary Antibodies

    Type
    Blog Post
    Published
    Dec. 21, 2021, 2:15 p.m.
    ...primary antibody without interfering with the hypervariable region, where an antibody binds to its target...

  5. What's New in CRISPR - November 2021

    Type
    Blog Post
    Published
    Nov. 18, 2021, 2:15 p.m.
    ...CasMINI plasmids Efficient CRISPR editing with a hypercompact Cas12f1 and engineered guide RNAs Yong-Sam Kim...

  7. Working with Nuclear Receptors

    Type
    Blog Post
    Published
    July 15, 2014, 4:03 p.m.
    ... multitude of therapeutic indices, including hypertension, cancer, diabetes, cardiovascular disease, cholesterol...

  10. Viral Vectors 101: Chemogenetics

    Type
    Blog Post
    Published
    July 11, 2023, 1:15 p.m.
    ...such as the glycine receptor, will promote hyperpolarization. PSAM ligands The advantage of PSAMs lies ...

  11. Plasmids 101: Protein Expression

    Type
    Blog Post
    Published
    June 7, 2018, 1:17 p.m.
    ...optimized. Yeast cells are also known for hyperglycosylating proteins which may be an issue depending ...

  12. CRISPR 101: RNA Editing with Cas13

    Type
    Blog Post
    Published
    July 31, 2020, 12:30 p.m.
    ...editing. To increase A->G editing, they employed hyperactive ADAR constructs, like ADAR2DD(E488Q). They also...

  17. Five Popular Model Organisms, Part 2

    Type
    Blog Post
    Published
    Sept. 29, 2020, 1:15 p.m.
    ...cardiovascular disease, specifically stroke and hypertension (Iannaccone et al., 2009). Rodents have also...

  18. A Control for All Seasons

    Type
    Blog Post
    Published
    Oct. 5, 2023, 1:15 p.m.
    ...well-studied kinase known to prevent tau hyperphosphorylation. You could run brain samples from both groups...

  20. Viral Vectors 101: Optogenetic Tools

    Type
    Blog Post
    Published
    June 27, 2023, 1:15 p.m.
    ...Na+) against the concentration gradient and hyperpolarize the cell (Mattis et al., 2012). Bicistronic ...
Showing: 21 - 40 of 41 results