...Chemical Synapses in the Brain. Neuron 68:843–856. https://doi.org/10.1016/j.neuron.2010.11.021  Gambarotto D...helped researchers gain a deeper understanding of neuronal synapses, centrosomes, parasites, and more (Bertiaux...

...experimental systems. They demonstrated LOV-Turbo in neurons, in pulse-chase experiments, and more. Find LOV-Turbo...element (TRE) or the cFos promoter. For example, neurons treated with a phorbol ester activator gave fluorescent...Images of iPAK4 fibers in cultured rat hippocampal neurons. HaloTag dyes are switched from yellow to red at...

...lab develops iPSC-based models of neurodegenerative and neurovascular diseases. He worked on the described... Dominik Paquet is currently a Professor for Neurobiology at the Institute for Stroke and Dementia Research...

...-dCas9-p300 Core, as well as pLV-dCas9-p300-P2A-PuroR for lentiviral expression. Tet1 demethylase Ronggui... deposited pdCas9-DNMT3A-EGFP and pdCas9-DNMT3A-PuroR for targeted cytosine methylation in mammalian cells... cells. Co-expression markers EGFP and PuroR enable sorting and selection of transduced cells. Grant Challen...

...generating zebrafish transgenic lines to study neurodegenerative diseases. Listen to Our Segement on the Tol...Plasmid 2: AAV Vectors for tageting GABA-ergic interneurons. Listen to Our Segment on these new AAV Vectors...

...Getting ready for Society for Neuroscience Conference 2023? So are we! Come say hi to us at Addgene's...Conference New to SfN? Try A Novice's Perspective on Neuroscience - SfN17!   ...

...of his incredibly popular retroviral vector pBABE-puro. Read on to learn more about the fascinating history...including one of the first to confer resistance to puromycin, vastly decreasing the cost of stable selection...

... connections between BLA projection neurons and mPFC interneurons can be labelled with an AAV1 Cre virus...

...empty backbones for shRNA expression, such as pLKO.1 puro and pLKO.1 – TRC cloning vector. Lentiviral Plasmids...negative control, and empty backbones such as pBABE-puro for retroviral expression and pLVTHM, a lentiviral...

...test recombination efficiency. When expressed in neuronal cells, each line showed broad recombinase-dependent...hamster ovary (CHO) cells, as well as in cortical neurons in layer 2/3 of the mouse brain. Rubin’s work shows...

... Rodrigo Arturo Rivera Solís, Universidad Autónoma de Yucatán, Mexico Dr. Rodrigo Arturo Rivera Solís...

...CD90.1 selection marker, Thy1.1, in addition to puromycin resistance.  The MYC-CRISPR library targets E-...AAV tools to selectively control parvalbumin interneurons from the Dimidschstein Lab More GCaMP8 ready-to-use...

...and chemogenetics communities to activate neurons and neuronal pathways using light and chemicals respectively...

...including neuronal and gut stem cells, dendritic cells, embryonic fibroblasts, glia cells and neurons, and ...

...sodium-potassium pump expressed specifically in neurons of the brain. McSweeney says they now think that...that mutations in the gene may prevent neurons from returning to basal conditions normally after periods...

...Tales of Music and the Brain by Oliver Sacks "Neurologist Oliver Sacks examines the relationship between...Musicophilia includes case studies of relevant neurological atypicalities, including a patient with amusia...

...serotonin is a well-known but poorly studied neuromodulator, and evidence suggests that it is incredibly...the question of whether firing of serotonergic neurons (measured using a red calcium sensor) leads to ...

... treated HeLa cells expressing FlipGFP with staurosporine, which induces apoptosis by activating caspase...array of diseases and pathologies such as neurodegenerative diseases, autoimmune disorders, and cancer...

.... Exo-AAV9 was successfully shown to transduce neurons in the brain after systemic (i.v.) delivery in ...stromal cells after intravenous delivery." Journal of neuro-oncology 139.2 (2018): 293-305. PubMed PMID: 29767307...

...for successful transduction. In another example, neuronal gene expression by an anterograde AAV was shown...input-defined neural pathways for defense behaviors." Neuron 93.1 (2017): 33-47. PubMed PMID: 27989459. PubMed...