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We narrowed to 532 results for: invs

Showing: 81 - 100 of 532 results

  1. Fostering communication in remote collaborations

    Type
    Blog Post
    ...also present hurdles for the team of researchers involved. Communication is a major challenge when researchers...Set and manage expectations When the researchers involved in a project are scattered across the globe, it...labs. This is an opportunity for the researchers involved to learn techniques from each other, access specialized...to specialized microscopes and allowed me to investigate my protein of interest in a French clinical cohort...immediately discuss the feedback with everyone involved can speed up the future directions of the project...

  2. Seven Tips for Using LinkedIn as a Scientist

    Type
    Blog Post
    ... ability to send invitations. Finally, if you don’t know clearly why you are inviting someone to connect... box, it will send an unpersonalized, generic invitation. Don’t try to connect from the LinkedIn phone... app either as this also results in a generic invitation. 3) Connect with people you have really talked... with this and as long as you personalize the invitation with your intention for connecting, this is probably...

  3. CRISPR in the Clinic

    Type
    Blog Post
    ...strategies for CRISPR therapies. Systemic therapies involve CRISPR-Cas delivery directly to the patient. Patient-derived...returned to the patient. Finally, allogenic therapies involve editing healthy donor-derived cells and delivering... treatment strategies for these disorders have involved turning on fetal hemoglobin to compensate for ...returning them to the patient. The first human trial involving CRISPR Cas9 for these diseases was sponsored by...evolving, and many of the challenges with therapies involve patient safety, effectiveness, and delivery. Patient...

  4. Transgenic Organisms, Cas9 Gene Drives, and Appropriate Safeguards

    Type
    Blog Post
    ...damage public trust in scientists, experiments involving potential gene drives should be conducted with...strategies are available? Molecular confinement involves building gene drives that can spread through populations... been tested in yeast5. Ecological confinement involves performing experiments in a geographic area where...relevant mosquito species. Reproductive confinement involves working with laboratory organisms that can't reproduce...publications. Thank you to our guest blogger! An inventor of technologies that harness evolution, Kevin ...

  5. 27 Hot Plasmids from 2016

    Type
    Blog Post
    ...library and used this library to screen for genes involved in West Nile Virus (WNV) induced cell death. The...for their gene of interest. Although the parts involved in altering gene expression are relatively well...can be quite arduous. The cloning process alone involves much literature searching, DNA synthesis, and ... Collection 2.0 Ras proteins are small GTPases involved in cell signaling pathways that control many cellular...AID technologies provides a clever means of investigating hard-to-study genes in hard-to-study cell types...screening is an efficient approach to identify genes involved in drug-resistance. Remarkably, this method also... gondii fitness. Sixteen of these genes were investigated for functions during infection of human cells...

  6. Sonic Hedgehog? Sleeping Beauty? Learn About the Genes Behind Addgene’s Conference Room Names

    Type
    Blog Post
    ...factors to repress the expression of genes primarily involved in development. These genes are known to play ... a comic book his daughter was reading. SHH is involved in the hedgehog signalling pathway, which is a...resemble spaghetti. We have two plasmids in our inventory from the lab of Eric Wieschaus that express sqh...Azplazu and Frasch, 1993). Tinman is specifically involved in the formation of the heart amongst other things...Transcriptional activation in Drosophila spermatogenesis involves the mutually dependent function of aly and a novel...

  7. Advancing Biology with Zebrafish: Genetic Tools for Developmental Studies and More

    Type
    Blog Post
    ...in a range of biological studies, including investigations into environmental pollutants and health, embryo...developmental biology that arose from zebrafish-based investigations. Genetic resources for zebrafish A common ...about the genome are powerful resources for investigating any biological process. High quality genome ...are particularly well-suited for neuroscience investigations. For example, neuronal activity can be tracked... and labor-intensive maintenance compared to invertebrate model systems, and their resistance (so far)...

  8. Synthetic Biology, Artificial Chromosomes, iGEM & More - Interview with Tom Ellis

    Type
    Blog Post
    ...team also investigates bacteria and extremophiles for biotechnology and has been directly involved in supervising... through Open Access. Chapter 7/Outro: Tom’s Involvement with iGEM and Addgene  Many thanks to our guest... He returned to academic research in 2005 to investigate synthetic biology at Boston University, working...

  9. Developing Transferable Skills During Science Training

    Type
    Blog Post
    ... website, write a blog Pursue speaking invitations by inviting others (be on a speaker committee) Follow...undergrads or less experienced grads Manage a project involving multiple scientists, create and stick to timelines...science careers is that a team is almost always involved. Demonstrating your ability to work well with ...

  10. CRISPR Protocol for Genomic Deletions in Mammalian Cell Lines [Video]

    Type
    Blog Post
    ...efficiency of the method. One observation was an inverse relationship between deletion size and frequency...outcome to deletions following paired DSBs is inversions [3]. These rearranged segments may also be informative...nondeleted allele is likely to bear an indel or inversion mutation [3]. In the CRISPR era, the genomic landscape...Bauer is a pediatric hematologist and principal investigator at Boston Children’s Hospital and Harvard Medical...

  11. Embracing Serendipity: A Crucial Element in the PhD Journey

    Type
    Blog Post
    .... Widening your search The first step towards inviting serendipity into your research lies in expanding...approaches One approach to achieve this goal could involve participating in interdisciplinary seminars, such...Additionally, journaling in the morning has proven invaluable for me, allowing me to pinpoint areas of my career...openness to unexpected possibilities, you not only invite serendipity into your research but also cultivate...

  12. History of CRISPR Cas - A tale of survival and evolution

    Type
    Blog Post
    ...various cas genes not only to store a record of invading phages but to also destroy the phage upon re-exposure... the foreign DNA, a cut is made to destroy the invader. Wikipedia, accessed 25 November 2013. Author...systems provides powerful lines of defense against invading phages. Rising to the challenge - Evolution of...research. Do you have a cool idea or application that involves CRISPR/Cas technology? Let us know.  References...

  13. Why Add Sucrose? Improved Yields for Adeno-associated Virus Preparation

    Type
    Blog Post
    ...2016 Addgene’s research team has been actively investigating ways to improve viral vector production. Whether...Whether redesigning viral packaging plasmids, investigating different viral production strategies or developing...method to improve AAV yields. Although we only investigated 3 serotypes it’s possible that this approach...less time and resources resupplying our current inventory and more time providing new materials to the research...

  14. Summer SciComm: Science Storytelling

    Type
    Blog Post
    ...the superheroes win in the end. But we’re still invested in seeing how they do it.    Finding Conflict...even when we know the ending, we can still get invested in the journey? The same thing applies for science...communication, use conflict to get your audience invested in the more complex story, and then build on that...gives your audience a chance to get curious and invested in the research itself - and isn’t that sense ...

  15. Crowdfight, a Platform to Boost Scientific Collaboration During COVID-19 and Beyond

    Type
    Blog Post
    ...researchers, such as postdocs and principal investigators. They also come from many different scientific...scientific research. We continue to support those involved in COVID-19 research, but our new platform Crowdfight...we do in our Frequently Asked Questions. We also invite you to participate in the 1st Crowdfight Symposium...is a postdoctoral researcher at Instituto de Investigación Biomédica de Salamanca (IBSAL) and one of the...

  16. Cultivating Community Science at BosLab

    Type
    Blog Post
    ...to get involved with DIY bio If you’re not in the Boston area but are inspired to get involved, check ...personal projects in mind. Thus, to encourage more involvement and provide all our members the opportunity to...previous city-wide genomic studies and our study will involve getting the community to collect various soil samples...

  17. Science Career Options

    Type
    Blog Post
    ...roles involves on a dad-to-day basis. Often, it is hard to know what a job title actually involves, other...These skills show employers that you can fully investigate and solve a problem or complete a project, overcoming...passionate and capable. For example if the job involves traveling, showing that you are a highly organised...

  18. Addgene Welcomes John Doench to the Advisory Board

    Type
    Blog Post
    ...encompasses a variety of technologies to functionally investigate the human genome. Doench says he enjoys working...with RNAi in terms of determining what genes are involved in biological process X, you can do with CRISPR... of individual edits can be studied quickly. Involvement with Addgene Although Doench’s thorough understanding...understanding of CRISPR is what got him involved with Addgene - he says he’s “known of Addgene basically...

  19. How Addgene Creates Content

    Type
    Blog Post
    ...post, we invite you behind the scenes in our content writing process, and to even get involved yourself...standards. It’s always a work in progress! Get involved A lot of our content already comes from you and...depositors and customers are asking. So how can you get involved? Keep asking your burning questions and tell us...

  20. From Lab Bench to Leadership: Transitioning into Management as a PhD

    Type
    Blog Post
    ...solving technical problems in the lab, management involves a different skill set: mentoring, setting strategic...industry, but the transition wasn’t easy - I had to reinvent myself and redefine the value I could bring to...a solid foundation in the basics of management. Invest time in understanding key principles through books...and project management. Mentorship is another invaluable resource: connecting with mentors who have made...
Showing: 81 - 100 of 532 results