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We narrowed to 612 results for: gan

Showing: 581 - 600 of 612 results
  1. Chemogenetics Guide

    Type
    Guide
    ...small molecule ligand. The ideal chemogenetic tools are unresponsive to native ligands and are engineered...transmembrane proteins that bind a specific ligand. Ligand binding then activates G-proteins to modulate...unresponsive to endogenous ligands, could be activated by synthetic ligands. Specifically, Receptors Activated...insensitivity to endogenous ligands, have low constitutive activity, and their activating ligands have few, if any... Figure 2: DREADDs, their ligands, and signaling properties. DREADD Ligands Muscarinic-receptor based ...neurotransmission. This, and the fact that GPCR ligands can have high potency, which is potentially important... Activated Solely by Synthetic Ligands (RASSLs) based on κ-opiod receptors (Coward et al. 1998). These...
  2. Using AAV for Neuronal Tracing

    Type
    Blog Post
    ...transport is typically used for the trafficking of organelles, such as mitochondria, as well as macromolecules...
Showing: 581 - 600 of 612 results