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370 results

Showing: 181 - 210 of 370 results

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Mouse Validation (mVAL) CRISPR Library

Pooled Library

#159391

Purpose

Pooled CRISPR library targets core intrinsic immune evasion genes

Depositor

Jason Moffat

Article

Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available since

Nov. 9, 2020

Availability

Academic Institutions and Nonprofits only
Mouse Toronto KnockOut (mTKO) CRISPR Library - pLCKO2

Pooled Library

#159393

Purpose

Mouse lentiviral genome-wide CRISPR library

Depositor

Jason Moffat

Article

Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available since

Nov. 9, 2020

Availability

Academic Institutions and Nonprofits only
LX-miR

Pooled Library

#112200

Purpose

gRNA library targets human primary miRNAs

Depositor

Ren-Jang Lin

Article

Kurata et al RNA. 2018 May 2. pii: rna.066282.118. do

Expression

Mammalian

Species

Homo sapiens

Use

Lentiviral

Available since

Sept. 20, 2018

Availability

Academic Institutions and Nonprofits only
pre-associated oBC-minP-GFP-mBC backbone (p043)

Pooled Library

#194098

Purpose

pre-associated oBC-minP-GFP-mBC backbone (p043), can directly be used to deposit library of regulatory elements

Depositor

Jay Shendure

Article

Lalanne et al bioRxiv 2022.12.10.519236

Expression

Bacterial and Mammalian

Use

RNAi

Available since

April 3, 2024

Availability

Academic Institutions and Nonprofits only
Human Lentiviral sgRNA Library - Kinases

Pooled Library

#51044

Purpose

Sub-pool of Sabatini/Lander sgRNA library enriched for kinase targets.

Depositor

Eric Lander, David Sabatini

Article

Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Feb. 7, 2014

Availability

Academic Institutions and Nonprofits only
Bassik lab Mouse CRISPR-Cas9 Deletion Library - Apoptosis and cancer

Pooled Library

#1000000121

Purpose

CRISPR gRNA mouse knockout pooled library - Apoptosis and cancer

Depositor

Michael Bassik

Available since

May 23, 2018

Availability

Academic Institutions and Nonprofits only
Barcode Library 0 (BCL0)

Pooled Library

#179851

Purpose

Lentiviral barcode library that consists of 10^6 unique barcodes. Barcodes consist of 12bp degenerate region followed by two stable bases (C or G) and 4bp unique library code ACGT.

Depositor

Jason Moffat

Article

Rehman et al Cell. 2021 Jan 7;184(1):226-242.e21. doi

Expression

Mammalian

Use

Lentiviral

Available since

May 12, 2022

Availability

Academic Institutions and Nonprofits only
Wei lab paired-guide RNA (pgRNA) CRISPR–Cas9 library for human long non-coding RNAs (lncRNAs)

Pooled Library

#89640

Purpose

Paired sgRNA library containing 12,472 pgRNAs targeting 671 human long non-coding RNAs (lncRNAs)

Depositor

Wensheng Wei

Article

Zhu et al Nat Biotechnol. 2016 Dec;34(12):1279-128

Expression

Mammalian

Use

Lentiviral

Available since

May 17, 2017

Availability

Academic Institutions and Nonprofits only
Human Brunello kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

Pooled Library

#75312

Purpose

Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

June 27, 2016

Availability

Academic Institutions and Nonprofits only
pEPIP_PepTile_40merFragments_65CancerDrivers

Pooled Library

#172109

Purpose

Lentiviral peptide expression library for overexpression fitness screening

Depositor

Prashant Mali

Article

Ford et al Cell Syst. 2021 Jul 21;12(7):716-732.e7.

Use

Lentiviral

Available since

Oct. 21, 2021

Availability

Academic Institutions and Nonprofits only
pCMV-Rep78/68 Scanning Saturation Mutagenesis (SSM)

Pooled Library

#198050

Purpose

By supplying an AAV cap gene of interest in trans, researchers can use this library to investigate the effects of rep mutations on production of a wide range of AAV capsid serotypes

Depositor

George Church

Article

Jain et al bioRxiv 2023.01.31.526541

Expression

Mammalian

Use

AAV

Available since

May 4, 2023

Availability

Academic Institutions and Nonprofits only
Bassik lab Mouse CRISPR-Cas9 Deletion Library - Stress Proteostasis

Pooled Library

#1000000125

Purpose

CRISPR gRNA mouse knockout pooled library - Stress proteostasis

Depositor

Michael Bassik

Available since

May 23, 2018

Availability

Academic Institutions and Nonprofits only
Human Lentiviral sgRNA Library - Nuclear

Pooled Library

#51047

Purpose

Sub-pool of Sabatini/Lander sgRNA library enriched for nuclear targets.

Depositor

Eric Lander, David Sabatini

Article

Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Feb. 7, 2014

Availability

Academic Institutions and Nonprofits only
mCRISPRa-v2, genome-wide, 10 sgRNAs/gene

Pooled Library

#1000000093

Purpose

Genome-wide CRISPR gRNA pooled library for activation of mouse genes

Depositor

Jonathan Weissman

Available since

Nov. 15, 2016

Availability

Academic Institutions and Nonprofits only
Human lentiviral CRISPR library_v1

Pooled Library

#69763

Purpose

Genome-scale sgRNA screening library in lentiviral vector pLB, targeting 20,121 human protein-coding genes

Depositor

Haoquan Wu

Article

Ma et al Cell Rep. 2015 Jul 28;12(4):673-83. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Feb. 9, 2016

Availability

Academic Institutions and Nonprofits only
hCRISPRa_dual_1_2

Pooled Library

#187249

Purpose

Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

Depositor

Marco Jost, Jonathan Weissman

Article

Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

Species

Synthetic

Use

Lentiviral

Available since

Sept. 30, 2022

Availability

Academic Institutions and Nonprofits only
Humagne Set C

Pooled Library

#172650

Purpose

Set C contains best-ranked guides 1 and 4.

Depositor

John Doench, David Root

Article

DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

Expression

Mammalian

Available since

Nov. 10, 2021

Availability

Academic Institutions and Nonprofits only
PYR1 Double Mutant Library

Pooled Library

#1000000181

Depositor

Timothy Whitehead

Available since

June 21, 2022

Availability

Academic Institutions and Nonprofits only
STICR_Index3

Pooled Library

#186335

Purpose

High Complexity Lentiviral Barcode Library

Depositor

Tomasz Nowakowski

Article

Delgado et al Nature. 2021 Dec 15. pii: 10.1038/s41586

Expression

Mammalian

Species

Synthetic

Use

Lentiviral

Available since

Sept. 12, 2022

Availability

Academic Institutions and Nonprofits only
Humagne Set D

Pooled Library

#172651

Purpose

Set D contains best-ranked guides 2 and 3.

Depositor

John Doench, David Root

Article

DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

Expression

Mammalian

Available since

Nov. 10, 2021

Availability

Academic Institutions and Nonprofits only
Liu Lab MusCK Library A

Pooled Library

#174196

Purpose

MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK A contains 5 gRNAs per gene.

Depositor

Xiaole Shirley Liu

Article

Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available since

Oct. 29, 2021

Availability

Academic Institutions and Nonprofits only
CRISPRi non-coding library (CRiNCL) - Common to all 7 cell lines

Pooled Library

#86538

Depositor

Jonathan Weissman

Article

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

Available since

March 8, 2017

Availability

Academic Institutions and Nonprofits only
SARS-CoV-2 RBD Wuhan-Hu-1 SSM Library

Pooled Library

#1000000182

Depositor

Jesse Bloom

Available since

June 14, 2022

Availability

Academic Institutions and Nonprofits only
Sabatini/Lander Lab Activity-Optimized Genome-wide Human sgRNA Library in pLenti-sgRNA

Pooled Library

#1000000095

Purpose

CRISPR gRNA knockout pooled library for targeting the human genome

Depositor

Eric Lander, David Sabatini

Available since

April 3, 2017

Availability

Academic Institutions and Nonprofits only
hCRISPRi-v2, Cancer and Apoptosis (h2), top 5 sgRNAs/gene

Pooled Library

#83972

Purpose

Human CRISPRi Pooled Library targeting cancer and apoptosis genes

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Dec. 14, 2016

Availability

Academic Institutions and Nonprofits only
Human Lentiviral sgRNA Library - Cell Cycle

Pooled Library

#51046

Purpose

Sub-pool of Sabatini/Lander sgRNA library enriched for cell cycle-related targets.

Depositor

Eric Lander, David Sabatini

Article

Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Feb. 7, 2014

Availability

Academic Institutions and Nonprofits only
sgRNA pool for Streptococcus pneumoniae

Pooled Library

#170432

Purpose

CRISPR library targeting S. pneumoniae D39V

Depositor

Jan-Willem Veening

Article

Liu et al Cell Host Microbe. 2021 Jan 13;29(1):107

Expression

Bacterial

Use

CRISPR

Available since

Aug. 31, 2021

Availability

Academic Institutions and Nonprofits only
pUC57kan-T7-mt-gRNA library

Pooled Library

#82480

Purpose

Pool of sgRNAs to remove mouse mitochondrial DNA reads in the sequencing of genomic libraries

Depositor

Wei Xie

Article

Wu et al Nature. 2016 Jun 30;534(7609):652-7.

Available since

April 5, 2017

Availability

Academic Institutions and Nonprofits only
Human Lentiviral sgRNA Library - Control

Pooled Library

#51048

Purpose

Sub-pool of Sabatini/Lander sgRNA library enriched for control targets.

Depositor

Eric Lander, David Sabatini

Article

Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Feb. 7, 2014

Availability

Academic Institutions and Nonprofits only
scQers promoter control series (p027, p028, p029, p041, p042)

Pooled Library

#1000000239

Depositor

Jay Shendure

Available since

April 3, 2024

Availability

Academic Institutions and Nonprofits only

Showing: 181 - 210 of 370 results

Results per page:

Sort results by:

Mouse Validation (mVAL) CRISPR Library

Mouse Toronto KnockOut (mTKO) CRISPR Library - pLCKO2

LX-miR

pre-associated oBC-minP-GFP-mBC backbone (p043)

Human Lentiviral sgRNA Library - Kinases

Bassik lab Mouse CRISPR-Cas9 Deletion Library - Apoptosis and cancer

Barcode Library 0 (BCL0)

Wei lab paired-guide RNA (pgRNA) CRISPR–Cas9 library for human long non-coding RNAs (lncRNAs)

Human Brunello kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

pEPIP_PepTile_40merFragments_65CancerDrivers

pCMV-Rep78/68 Scanning Saturation Mutagenesis (SSM)

Bassik lab Mouse CRISPR-Cas9 Deletion Library - Stress Proteostasis

Human Lentiviral sgRNA Library - Nuclear

mCRISPRa-v2, genome-wide, 10 sgRNAs/gene

Human lentiviral CRISPR library_v1

hCRISPRa_dual_1_2

Humagne Set C

PYR1 Double Mutant Library

STICR_Index3

Humagne Set D

Liu Lab MusCK Library A

CRISPRi non-coding library (CRiNCL) - Common to all 7 cell lines

SARS-CoV-2 RBD Wuhan-Hu-1 SSM Library

Sabatini/Lander Lab Activity-Optimized Genome-wide Human sgRNA Library in pLenti-sgRNA

hCRISPRi-v2, Cancer and Apoptosis (h2), top 5 sgRNAs/gene

Human Lentiviral sgRNA Library - Cell Cycle

sgRNA pool for Streptococcus pneumoniae

pUC57kan-T7-mt-gRNA library

Human Lentiviral sgRNA Library - Control

scQers promoter control series (p027, p028, p029, p041, p042)

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