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Plasmid#182945PurposeTo express a multi-neurotrophin made from the Human NT-3 gene. The secreted protein that can bind only all 3 TRK receptors and not p75NTRDepositorUseSynthetic BiologyTagsExpressionMammalianMutationPromoterCMV promoter and enhancerAvailable sinceApril 21, 2022AvailabilityAcademic Institutions and Nonprofits only
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pLV-MNTS-1
Plasmid#182944PurposeTo express a multi-neurotrophin made from the Human NT-3 gene. The secreted protein can bind all 3 TRK receptors and p75NTRDepositorInsertMNTS-1 (NTF3 Homo sapiens, Synthetic, Human)
UseLentiviralTagsExpressionMammalianMutationThis is the Human NT-3 with mutations on the matu…PromoterCMV promoter and enhancerAvailable sinceApril 21, 2022AvailabilityAcademic Institutions and Nonprofits only -
pmiRGLO Dual-Luciferase-PIK3R1-3'UTR
Plasmid#182252PurposeHuman PIK3R1 3` UTR region containing 1x binding site for miR-150 cloned downstream of luciferase reporter geneDepositorInsert3' UTR region of PIK3R1 gene
UseLuciferaseTagsExpressionMammalianMutationPromoterAvailable sinceMarch 24, 2022AvailabilityAcademic Institutions and Nonprofits only -
pCDH_CMV_dC_mKate2
Plasmid#167336PurposeExpresses mKatet2 fused to TFAM dC-tail mutant in mammalian cellsDepositorInsertTFAM (TFAM Human)
UseLentiviralTagsmKate2ExpressionMammalianMutationTruncation mutant containing MTS (1-42) as well a…PromoterCMVAvailable sinceApril 15, 2021AvailabilityAcademic Institutions and Nonprofits only -
pLenti-sgCTRL-1
Plasmid#83934PurposeLentiviral vector expressing a control sgRNA. NOTE: This plasmid does NOT contain Cas9.DepositorInsertsgCTRL-1
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterU6Available sinceFeb. 1, 2021AvailabilityAcademic Institutions and Nonprofits only -
pLenti-sgCTRL-2
Plasmid#83935PurposeLentiviral vector expressing a control sgRNA. NOTE: This plasmid does NOT contain Cas9.DepositorInsertsgCTRL-2
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterU6Available sinceFeb. 1, 2021AvailabilityAcademic Institutions and Nonprofits only -
pLenti-sgCTRL-3
Plasmid#83936PurposeLentiviral vector expressing a control sgRNA. NOTE: This plasmid does NOT contain Cas9.DepositorInsertsgCTRL-3
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterU6Available sinceFeb. 1, 2021AvailabilityAcademic Institutions and Nonprofits only -
mTurquoise2-RnBarr1
Plasmid#137795PurposeVisualization of beta-arrestin2DepositorInsertRat beta-arrestin 1 (Arrb1 Rat)
UseTagsExpressionMammalianMutationPromoterCMVAvailable sinceFeb. 26, 2020AvailabilityAcademic Institutions and Nonprofits only -
shCTL-mlpx-neo
Plasmid#65233Purposeencodes a non-targeting control shRNADepositorInsertnon-coding shRNA
UseTagsExpressionMammalianMutationPromoterPGKAvailable sinceAug. 12, 2015AvailabilityAcademic Institutions and Nonprofits only -
pTYB-pLAC-F112S
Plasmid#48727PurposeBacterial expression of Lacritin Protein with Mutation at protein 112 from Phenylalanine to SerineDepositorInsertLacritin (LACRT Human)
UseTagsInteinExpressionBacterialMutationPhenylalanine 12 to SerinePromoterT7Available sinceOct. 28, 2013AvailabilityAcademic Institutions and Nonprofits only -
pTYB1-pLAC-I98S
Plasmid#48723PurposeBacterial expression of Lacritin Protein with Mutation at protein 98 from Isoleucine to SerineDepositorInsertLacritin (LACRT Human)
UseTagsInteinExpressionBacterialMutationIsoleucine 98 to SerinePromoterT7Available sinceOct. 28, 2013AvailabilityAcademic Institutions and Nonprofits only -
pTYB1-pLAC-I73S
Plasmid#48722PurposeBacterial expression of Lacritin Protein with Mutation at protein 73 from Isoleucine to SerineDepositorInsertLacritin (LACRT Human)
UseTagsInteinExpressionBacterialMutationIsoleucine 73 to SerinePromoterT7Available sinceOct. 28, 2013AvailabilityAcademic Institutions and Nonprofits only -
pTYB1-pLAC-V69S
Plasmid#48721PurposeBacterial expression of Lacritin Protein with Mutation at protein 69 from Valine to SerineDepositorInsertLacritin (LACRT Human)
UseTagsInteinExpressionBacterialMutationValine 69 to SerinePromoterT7Available sinceOct. 18, 2013AvailabilityAcademic Institutions and Nonprofits only -
PT3.5/CMV-EGFRvIII
Plasmid#20280DepositorInsertEGFRvII (EGFR Human)
UseTransposonTagsExpressionMutationSee depositor comments below.PromoterAvailable sinceDec. 3, 2009AvailabilityAcademic Institutions and Nonprofits only -
pCDH_blast_MCS_Nard_GFP_LAMIN
Plasmid#167340PurposeExpresses GFP fused to lamin A (LA) in mammalian cellsDepositorInsertLamin A (LMNA Human)
UseLentiviralTagsGFPExpressionMammalianMutationPromoterCMVAvailable sinceApril 15, 2021AvailabilityAcademic Institutions and Nonprofits only -
pLVX-TetOne-Puro-mitoEcSTH-FLAG
Plasmid#218629PurposeThis plasmid contains human codon optimized sequence of mitoEcSTH which is a soluble transhydrogenase from E. coli that can be used to increase NADH/NAD+ ratio in mammalian cells.DepositorInsertmitoEcSTH
UseLentiviral and Synthetic BiologyTagsFLAG and MTSExpressionMammalianMutationPromoterAvailable sinceMay 1, 2024AvailabilityAcademic Institutions and Nonprofits only -
pWPI-N3ICD
Plasmid#185524PurposeConstitutive overexpression of human NOTCH3 intracellular domainDepositorInsertNOTCH3 intracellular domain (NOTCH3 Human)
UseLentiviralTagsExpressionMutationPromoterEF-1aAvailable sinceFeb. 5, 2024AvailabilityAcademic Institutions and Nonprofits only -
pLVX-TetOne-Puro-EcSTH-FLAG
Plasmid#218628PurposeThis plasmid contains human codon optimized sequence of EcSTH which is a soluble transhydrogenase from E. coli that can be used to increase NADH/NAD+ ratio in mammalian cells.DepositorInsertEcSTH
UseLentiviral and Synthetic BiologyTagsFLAGExpressionMammalianMutationPromoterAvailable sinceMay 1, 2024AvailabilityAcademic Institutions and Nonprofits only -
pWPI-N1ICD
Plasmid#185525PurposeConstitutive overexpression of human NOTCH1 intracellular domainDepositorInsertNOTCH1 intracellular domain (NOTCH1 Human)
UseLentiviralTagsExpressionMutationPromoterEF-1aAvailable sinceFeb. 5, 2024AvailabilityAcademic Institutions and Nonprofits only -
pLKO-RB1-shRNA19
Plasmid#25640Purpose3rd generation lentiviral vectorDepositorInsertRB1-shRNA 19 (RB1 Human)
UseLentiviral and RNAiTagsExpressionMammalianMutationPromoterAvailable sinceJune 21, 2010AvailabilityAcademic Institutions and Nonprofits only