Addgene

Showing: 11161 - 11180 of 19201 results

Results per page:

Sort results by:

NPR1 gRNA (BRDN0001148927)

Plasmid

#77306

Purpose

3rd generation lentiviral gRNA plasmid targeting human NPR1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

NPR1 (NPR1 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
SYK gRNA (BRDN0001148390)

Plasmid

#76776

Purpose

3rd generation lentiviral gRNA plasmid targeting human SYK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SYK (SYK Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
SYK gRNA (BRDN0001146783)

Plasmid

#76778

Purpose

3rd generation lentiviral gRNA plasmid targeting human SYK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SYK (SYK Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-EGFR-Y764_V765insHH

Plasmid

#116319

Purpose

Lentiviral expression of EGFR Y764_V765insHH

Depositor

Kenneth Scott, Gordon Mills

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

EGFR (EGFR Human)

Use

Lentiviral

Tags

Expression

Mutation

Y764_V765insHH

Promoter

Available since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pFUPI AoT5Cyp

Plasmid

#80280

Purpose

Expresses Aotus TRIM5 CypA fusion

Depositor

Jeremy Luban

Article

Neagu et al J Clin Invest. 2009 Oct;119(10):3035-47.

Insert

TRIM5 CypA fusion

Use

Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

Available since

Aug. 3, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
TRCN0000279953

Plasmid

#78154

Purpose

shCDK4 targeting CDS

Depositor

William Hahn

Article

Hong et al Nat Commun. 2016 Jun 22;7:11987. doi: 10

Insert

CDK4 (CDK4 Human)

Use

Lentiviral and RNAi

Tags

Expression

Mutation

Promoter

hU6 and hU6

Available since

June 22, 2016

Availability

Academic Institutions and Nonprofits only
pLV floxed hMyoD-IRES-dsRed

Plasmid

#66632

Purpose

co-expresses CRE excisable human MyoD and dsRed

Depositor

Charles Gersbach

Insert

human MyoD IRES dsRed (MYOD1 Human)

Use

Cre/Lox and Lentiviral

Tags

Expression

Mutation

Promoter

hUbC

Available since

April 12, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
SEPHS2 gRNA (BRDN0001146226)

Plasmid

#77662

Purpose

3rd generation lentiviral gRNA plasmid targeting human SEPHS2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SEPHS2 (SEPHS2 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
SEPHS2 gRNA (BRDN0001147864)

Plasmid

#77663

Purpose

3rd generation lentiviral gRNA plasmid targeting human SEPHS2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SEPHS2 (SEPHS2 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
FuPick-shRNA

Plasmid

#31614

Depositor

Robert Malenka

Article

Citri et al J Neurosci. 2010 Dec 8. 30(49):16437-52.

Insert

PICK1 shRNA (Pick1 Rat)

Use

Lentiviral and RNAi

Tags

GFP

Expression

Mammalian

Mutation

Promoter

Available since

Aug. 18, 2011

Availability

Academic Institutions and Nonprofits only

Enlarge
SASS6 G2.3 gRNA

Plasmid

#90885

Purpose

3rd generation lentiviral gRNA plasmid targeting human SASS6

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

SASS6 (Guide Designation G2.3)

Use

CRISPR and Lentiviral

Tags

Expression

Mutation

Promoter

U6

Available since

July 20, 2017

Availability

Academic Institutions and Nonprofits only

Enlarge
CAMKK2 gRNA (BRDN0001146379)

Plasmid

#76699

Purpose

3rd generation lentiviral gRNA plasmid targeting human CAMKK2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CAMKK2 (CAMKK2 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPRv2-sgSORCS2-G2

Plasmid

#118416

Purpose

CRISPR knockout, expresses Cas9, and sgRNA targeting Human SORCS2

Depositor

Mark Denham

Article

Hojland Knudsen et al Front Cell Dev Biol. 2018 May 15;6:54. d

Insert

gRNA SORCS2 Human (SORCS2 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mutation

Promoter

Available since

Nov. 13, 2018

Availability

Academic Institutions and Nonprofits only

Enlarge
pCDH-SIRT6-G60A

Plasmid

#102326

Purpose

Human SIRT6 G60A for mammalian expression

Depositor

Hening Lin

Article

Zhang et al Nat Chem Biol. 2016 Aug;12(8):614-20. do

Insert

SIRT6 (SIRT6 Human)

Use

Lentiviral

Tags

None

Expression

Mammalian

Mutation

changed glycine 60 to alanine

Promoter

CMV

Available since

Oct. 12, 2018

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-BRAF-V600R

Plasmid

#116209

Purpose

Lentiviral expression of BRAF V600R

Depositor

Kenneth Scott, Gordon Mills

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

BRAF (BRAF Human)

Use

Lentiviral

Tags

Expression

Mutation

V600R

Promoter

Available since

Jan. 11, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pLL3.7-EF-EYFP-YAP1_Y357F-PolyA

Plasmid

#112287

Purpose

Fluorescently labels human YAP1-2gamma isoform (504 aa) Y357F mutant _ corresponding to tyrosine 407 in this isoform

Depositor

Erik Sahai

Article

Ege et al Cell Syst. 2018 Jun 27;6(6):692-708.e13.

Insert

EYFP-YAP1 (YAP1 Human)

Use

Lentiviral

Tags

Expression

Mutation

Tyrosine 357 to Phenyalanine corresponding to tyr…

Promoter

EF-1 alpha

Available since

May 13, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-ROR1-T69M

Plasmid

#116675

Purpose

Lentiviral expression of ROR1 T69M

Depositor

Kenneth Scott, Gordon Mills

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

ROR1 (ROR1 Human)

Use

Lentiviral

Tags

Expression

Mutation

T69M

Promoter

Available since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-RET-G533D

Plasmid

#116667

Purpose

Lentiviral expression of RET G533D

Depositor

Kenneth Scott, Gordon Mills

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

RET (RET Human)

Use

Lentiviral

Tags

Expression

Mutation

G533D

Promoter

Available since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-RET-G751E

Plasmid

#116668

Purpose

Lentiviral expression of RET G751E

Depositor

Kenneth Scott, Gordon Mills

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

RET (RET Human)

Use

Lentiviral

Tags

Expression

Mutation

G751E

Promoter

Available since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-RET-V121I

Plasmid

#116670

Purpose

Lentiviral expression of RET V121I

Depositor

Kenneth Scott, Gordon Mills

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

RET (RET Human)

Use

Lentiviral

Tags

Expression

Mutation

V121I

Promoter

Available since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge