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Plasmid#79797PurposeInsulin receptor isoform A with a inter-domain EBFP2 tag at extracellular region (between furin-like domain and transmembrane domain). For imaging insulin receptor trafficing.DepositorInsertInsRA (INSR Human)
UseTagsEBFP2 extracellularExpressionMammalianMutationPromoterCMVAvailable sinceAug. 5, 2016AvailabilityIndustry, Academic Institutions, and Nonprofits -
pcDNA3-ALK3 K261R
Plasmid#80875Purposemammalian expression of ALK3 K261RDepositorInsertALK3 (BMPR1A Human)
UseTagsHAExpressionMammalianMutationK261R (Kinase inactive)PromoterCMVAvailable sinceOct. 17, 2016AvailabilityAcademic Institutions and Nonprofits only -
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pD649-HAsp-TNFSF14-COMP5AP-AviTag-9xHis
Plasmid#157149PurposeMammalian expression of cell-surface protein extracellular domain fused to COMP5AP-AviTag-9xHis. Protein is secreted from cells.DepositorInsertTNFSF14 (TNFSF14 Human)
UseTagsCOMP5AP-AviTag-9xHisExpressionMammalianMutationPromoterCMV/SP6Available sinceMarch 8, 2023AvailabilityAcademic Institutions and Nonprofits only -
pCW57.kc1-HSD17B10
Plasmid#164076PurposeHuman codon optimized HSD17B10. Expression is controlled by doxycycline.DepositorInsertHSD17B10 (HSD17B10 Human)
UseTagsExpressionMammalianMutationPromoterAvailable sinceFeb. 17, 2021AvailabilityAcademic Institutions and Nonprofits only -
pD649-HAsp-TNFRSF12A-COMP5AP-AviTag-9xHis
Plasmid#157052PurposeMammalian expression of cell-surface protein extracellular domain fused to COMP5AP-AviTag-9xHis. Protein is secreted from cells.DepositorInsertTNFRSF12A (TNFRSF12A Human)
UseTagsCOMP5AP-AviTag-9xHisExpressionMammalianMutationPromoterCMV/SP6Available sinceMarch 8, 2023AvailabilityAcademic Institutions and Nonprofits only -
pAAV.CMV.CD86.C-HA
Plasmid#154848PurposeExpresses murine CD86 protein (T-lymphocyte activation antigen) with HA-tag at C-terminusDepositorInsertCluster of Differentiation 86 (Cd86 Mouse)
UseAAVTagsHA-tagExpressionMammalianMutationPromoterCMVAvailable sinceAug. 21, 2020AvailabilityAcademic Institutions and Nonprofits only -
TFORF3547
Plasmid#145023PurposeLentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.DepositorInsertCBFB (CBFB Human)
UseLentiviralTagsV5ExpressionMammalianMutationPromoterEF1aAvailable sinceJan. 5, 2023AvailabilityAcademic Institutions and Nonprofits only -
hu-TLR4 299/399 dual snp flag pDEST40
Plasmid#42648Purposedestination vector for expression of human TLR4 299/399 SNP in mammalian cellsDepositorInsertTLR4 299/399 SNP (TLR4 Human)
UseTagsFlagExpressionMammalianMutationD299G and T399IPromoterCMVAvailable sinceMarch 3, 2014AvailabilityAcademic Institutions and Nonprofits only -
INSR gRNA (BRDN0001145804)
Plasmid#75506Purpose3rd generation lentiviral gRNA plasmid targeting human INSRDepositorInsertINSR (INSR Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
GFP(N-glyc)-Tac-TC
Plasmid#162496PurposeExpresses partial length Tac (TMD and cytosolic tail) with GFP tag in the N-terminus in mammalian cells, and there is one N-glycosylation site in GFP tag.DepositorInsertpartial length Tac (TMD and cytosolic tail) (IL2RA Human)
UseTagsGFPExpressionMammalianMutationTac is in partial length with its TMD and cysotol…PromoterAvailable sinceJan. 29, 2021AvailabilityAcademic Institutions and Nonprofits only -
ALK gRNA (BRDN0001147509)
Plasmid#77392Purpose3rd generation lentiviral gRNA plasmid targeting human ALKDepositorInsertALK (ALK Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
ALK gRNA (BRDN0001148180)
Plasmid#77391Purpose3rd generation lentiviral gRNA plasmid targeting human ALKDepositorInsertALK (ALK Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
ALK gRNA (BRDN0001146138)
Plasmid#77393Purpose3rd generation lentiviral gRNA plasmid targeting human ALKDepositorInsertALK (ALK Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
ALK gRNA (BRDN0001146667)
Plasmid#77394Purpose3rd generation lentiviral gRNA plasmid targeting human ALKDepositorInsertALK (ALK Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
INSR gRNA (BRDN0001148089)
Plasmid#75507Purpose3rd generation lentiviral gRNA plasmid targeting human INSRDepositorInsertINSR (INSR Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
INSR gRNA (BRDN0001149243)
Plasmid#75508Purpose3rd generation lentiviral gRNA plasmid targeting human INSRDepositorInsertINSR (INSR Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
pStreptagIIx2 Alfatag 3C InsR EABR
Plasmid#234996PurposeFor production of Extracellular Vesicles (EVs), with the Insulin Receptor Strep-tag II labeled on their surfaceDepositorInsertInsR-EABR (INSR Human)
UseTags2xStreptag-II, Alfatag, HRV 3C siteExpressionMammalianMutationPromoterAvailable sinceApril 22, 2025AvailabilityAcademic Institutions and Nonprofits only -
PD2529 human beta1 ecto
Plasmid#221398PurposeMammalian expression of human integrin beta1 ectodomainDepositorInsertintegrin beta1 ectodomain (ITGB1 Human)
UseTagsAVI tag, HRV3C cleavage site, basic coil, HA tag,…ExpressionMammalianMutationcodon optimized for human mature _1 residues Q1 t…PromoterAvailable sinceSept. 9, 2024AvailabilityAcademic Institutions and Nonprofits only -
Beta1 Q280* K418* full-length
Plasmid#221406PurposeMammalian expression of human integrin beta1 Q280* K418* full-lengthDepositorInsertintegrin beta1 Q280* K418* full-length (ITGB1 Human)
UseTagsCD33 secretion peptide (MPLLLLLPLLWAGALA) and HA …ExpressionMammalianMutationcodon-optimized mature sequencePromoterAvailable sinceJuly 15, 2024AvailabilityAcademic Institutions and Nonprofits only