Showing: 6341 - 6360 of 13935 results
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Plasmid#114276PurposeTET-inducible expression of DVL2 protein with a deletion of its DIX-domainDepositorInsertDVL2 (Dvl2 Mouse)
UseLentiviralTagsFLAGExpressionMutationdeletion of DIX domainPromoterAvailabilityAcademic Institutions and Nonprofits only -
pCLXEBR-pTF-cKit
Plasmid#114293PurposeTET-inducible expression of c-KitDepositorInsertcKit (Kit Mouse)
UseLentiviralTagsExpressionMutationPromoterAvailabilityAcademic Institutions and Nonprofits only -
pHAGE2-TetOminiCMV-SM
Plasmid#136578PurposeDox-inducible polycistronic lentiviral vector expressing mouse Sox2, cMycDepositorUseLentiviralTagsExpressionBacterialMutationPromotertetO-miniCMV (dox-inducible)AvailabilityAcademic Institutions and Nonprofits only -
pHAGE2-TetOminiCMV-Klf4
Plasmid#136613PurposeDox-inducible lentiviral vector expressing mouse Klf4DepositorInsertKlf4 (Klf4 Mouse)
UseLentiviralTagsExpressionBacterialMutationPromotertetO-miniCMV (dox-inducible)AvailabilityAcademic Institutions and Nonprofits only -
FUG-T2A-F241S
Plasmid#140740PurposeLentiviral vector to overexpress the autism-associated PTEN mutation F241S and GFP as two separate proteinsDepositorInsertGFP-T2A-PTENF241S (PTEN Human)
UseLentiviralTagsnoneExpressionMammalianMutationF241SPromoterhUbiCAvailabilityAcademic Institutions and Nonprofits only -
FUG-T2A-D252G
Plasmid#140741PurposeLentiviral vector to overexpress the autism-associated PTEN mutation D252G and GFP as two separate proteinsDepositorInsertGFP-T2A-PTEND252G (PTEN Human)
UseLentiviralTagsnoneExpressionMammalianMutationD252GPromoterhUbiCAvailabilityAcademic Institutions and Nonprofits only -
FUG-T2A-W274L
Plasmid#140742PurposeLentiviral vector to overexpress the autism-associated PTEN mutation W274L and GFP as two separate proteinsDepositorInsertGFP-T2A-PTENW274L (PTEN Human)
UseLentiviralTagsnoneExpressionMammalianMutationW274LPromoterhUbiCAvailabilityAcademic Institutions and Nonprofits only -
pHS0537 CRISPR-associated IscB locus (Delaware Bay) in pBR322 with Fn spacer
Plasmid#176588PurposeEndogenous locus of CRISPR-associated IscB (Delaware Bay) with Fn spacerDepositorInsertCRISPR-associate IscB (Delaware Bay) locus
UseTagsExpressionBacterialMutationReplaced spacer in CRISPR array with Fn spacerPromoterAvailabilityAcademic Institutions and Nonprofits only -
EF1a_DIO_mMeCP2-HaloTag
Plasmid#164062PurposeDouble-Floxed Inverted Open reading frame for mouseMeCP2(alpha) Under EF1a promoterDepositorInsertMeCP2 Isoform 1 (Mecp2 Mouse)
UseAAVTagsHaloTagExpressionMammalianMutationPromoterEF1aAvailabilityAcademic Institutions and Nonprofits only -
EF1a_DIO_R106W-HaloTag
Plasmid#164063PurposeDouble-Floxed Inverted Open reading frame for mouseMeCP2(alpha) carrying R106W mutationDepositorInsertMeCP2 R106W (Mecp2 Mouse)
UseAAVTagsHaloTagExpressionMammalianMutationPromoterEF1AAvailabilityAcademic Institutions and Nonprofits only -
EF1a_DIO_R133C-HaloTag
Plasmid#164064PurposeDouble-Floxed Inverted Open reading frame for mouseMeCP2(alpha) carrying R133C mutationDepositorInsertMeCP2 Isoform 1 R133C (Mecp2 Mouse)
UseAAVTagsHaloTagExpressionMammalianMutationPromoterEF1aAvailabilityAcademic Institutions and Nonprofits only -
pαH-S-HRV3C/D614G
Plasmid#164568PurposeSARS-CoV-2 Spike protein with furin site mutated to HRV3C site and D614G mutation (S-HRV3C-D614G variant)DepositorInsertSpike (S-HRV3C-D614G variant)
UseTags2X Strep-Tag II and 8X His tagExpressionMammalianMutationD614GPromoterAvailabilityAcademic Institutions and Nonprofits only -
pcDNA3HA-AMOT p130∆PPxY2
Plasmid#166712Purposeexpresses AMOT with inactivating mutation in second PPxY motif in mammalian cellsDepositorInsertAngiomotin p130 P262A P263A (AMOT Human)
UseTags2xHAExpressionMammalianMutationchanged proline 262 to alanine, proline 263 to al…PromoterCMV promoterAvailabilityAcademic Institutions and Nonprofits only -
pcDNA3HA-AMOT p130∆PPxY3
Plasmid#166713Purposeexpresses AMOT with inactivating mutation in third PPxY motif in mammalian cellsDepositorInsertAngiomotin p130 P3072A P308A (AMOT Human)
UseTags2xHAExpressionMammalianMutationchanged proline 307 to alanine, proline 308 to al…PromoterCMV promoterAvailabilityAcademic Institutions and Nonprofits only -
AAV-hSyn-DIO-mCReP
Plasmid#167503PurposeConditional expression of the eIF2alpha phophatase, CReP (Ppp1r15b)DepositorInsertPpp1r15b (Ppp1r15b Mouse)
UseAAV and Cre/LoxTagsMycExpressionMammalianMutationPromoterhSynAvailabilityAcademic Institutions and Nonprofits only -
pET28a-TEV-U1AF37MF77M
Plasmid#168267PurposeExpresses human dmU1A with the F37M/F77M double mutantDepositorInsertU1A RRM1 crystallization module (SNRPA Human)
UseTags6xHis tag N-terminus, TEV protease cleavage siteExpressionBacterialMutationchanged F37M and F77MPromoterT7 promotorAvailabilityAcademic Institutions and Nonprofits only -
lentiCRISPR v2-Nr4a1 double gRNAs
Plasmid#162791PurposeMultiplex Guide RNAs to generate Nr4a1 knockout by CRISPRDepositorInsertMultiplex Nr4a1 gRNA 1 and 2 (Nr4a1 Mouse)
UseCRISPR and LentiviralTagsExpressionMutationPromoterhU6AvailabilityAcademic Institutions and Nonprofits only -
pMKO.1-shCcnb1
Plasmid#162793PurposeCcnb1 shRNA in pMKO.1 retroviral vectorDepositorInsertCcnb1 shRNA (Ccnb1 Mouse)
UseRNAi and RetroviralTagsExpressionMutationPromoterU6AvailabilityAcademic Institutions and Nonprofits only -
pT2AL200R150G-EGFP-LC3B-RFP-LC3BΔG
Plasmid#168998PurposeExpresses GFP-LC3-RFP-LC3ΔG in zebrafish to measure autophagic fluxDepositorInsertmicrotubule-associated protein 1 light chain 3 beta (Map1lc3b Rat)
UseUnspecifiedTagsEGFP and mRFP1ExpressionMutationPromoterAvailabilityAcademic Institutions and Nonprofits only -
pDTFendoNA2
Plasmid#174731PurposeExpresses DT386F-endoNA2 fusion protein for selective elimination of polysialic acid–containing cells. Truncated diphtheria toxin fused to noncatalytic endosialidase via a furin-cleavable linker.DepositorInsertDT386F
UseTagsExpressionBacterialMutationDeleted amino acids 412-560 (the receptor binding…PromoterAvailabilityAcademic Institutions and Nonprofits only
Showing: 6341 - 6360 of 13935 results