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Plasmid#125598Purposedoxycycline-inducible expression of human FOS in mammalian cellsDepositorInsertFos proto-oncogene, AP-1 transcription factor subunit (FOS Human)
UseLentiviralTagsExpressionMammalianMutationPromoterTRE-mCMVAvailable sinceJune 12, 2019AvailabilityAcademic Institutions and Nonprofits only -
pLenti-TRE-FH-TET3 short
Plasmid#166916PurposeLentivirus for inducible overexpression of human TET3 short isoform lacking CXXC domain (NM_001366022.1)DepositorInsertTET3 short isoform
UseLentiviralTagsHA TagExpressionMammalianMutationChanged nucleotide 18 (G) to (A) to delete FseI r…PromoterAvailable sinceMarch 14, 2024AvailabilityAcademic Institutions and Nonprofits only -
pEIGW-human KLF4
Plasmid#100131PurposeHuman KLF4 lentiviral expression vectorDepositorInsertKruppel like factor 4 (KLF4 Human)
UseLentiviralTagsExpressionMammalianMutationPromoterE1FAvailable sinceFeb. 17, 2018AvailabilityAcademic Institutions and Nonprofits only -
UCP3 promoter EP1
Plasmid#71743PurposeContains 7kb of the murine UCP3 gene encompassing the core promoter, exon 1, intron 1, and part of exon 2; used to quantify promoter activityDepositorInsertUncoupling Protein 3 promoter (Ucp3 Mouse)
UseTagsLuciferaseExpressionBacterialMutationContains 7kb of the murine UCP3 gene encompassing…PromoterUCP3Available sinceJan. 19, 2016AvailabilityAcademic Institutions and Nonprofits only -
pLV-PLXNB2-mGAP
Plasmid#86241PurposeLentivirus for expression of human Plexin-B2 with mutant GAP domainDepositorInsertPlexin-B2 (PLXNB2 Human)
UseLentiviralTagsExpressionMammalianMutationPLXNB2 with point mutations of GAP domainPromoterhPGKAvailable sinceJan. 13, 2021AvailabilityAcademic Institutions and Nonprofits only -
pLKO_NWS.HA.V5_mCherry-NLS
Plasmid#178283PurposeNuclear Protein Barcode (nPC) for vector/cell tracking. Contains U6 trRNA cassette for sgRNA cloning. Enables spatial detection of CRISPR screens.DepositorInsertnPC Tagged mCherry-NLS
UseLentiviralTagsNWS.HA.V5 and Nuclear Localization SignalExpressionMutationPromotereF1aAvailable sinceJan. 27, 2022AvailabilityAcademic Institutions and Nonprofits only -
pCCLc-U6-shHMGA2.3-PGK-dTomato
Plasmid#89606PurposeSilencing Hmga2 in human cellsDepositorInsertshRNA targeting HMGA2 (HMGA2 Human)
UseLentiviralTagsExpressionMammalianMutationPromoterU6Available sinceJuly 20, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR221_SLC39A13
Plasmid#132117PurposeGateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectorsDepositorInsertSLC39A13 (SLC39A13 Human)
UseTagsExpressionMammalianMutationPromoterAvailable sinceDec. 4, 2019AvailabilityIndustry, Academic Institutions, and Nonprofits -
pLV-tetO-HA-GFI1B
Plasmid#125599Purposedoxycycline-inducible expression of human GFI1B (HA tagged) in mammalian cellsDepositorInsertGrowth Factor Independent 1B transcriptional repressor (GFI1B Human)
UseLentiviralTagsHA tagExpressionMammalianMutationPromoterTRE-mCMVAvailable sinceJune 12, 2019AvailabilityAcademic Institutions and Nonprofits only -
pDONR221_SLC8A3
Plasmid#132186PurposeGateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectorsDepositorInsertSLC8A3 (SLC8A3 Human)
UseTagsExpressionMammalianMutationPromoterAvailable sinceOct. 25, 2019AvailabilityIndustry, Academic Institutions, and Nonprofits -
pGEX-6P1-hPXR-LBD
Plasmid#67769PurposeExpression GST-hPXR-LBD in bacteriaDepositorInserthuman pregnane X receptor (PXR) ligand binding domain (NR1I2 Human)
UseTagsGSTExpressionBacterialMutationContains amino acids 107 to 434 of human PXRPromoterTacAvailable sinceJuly 22, 2015AvailabilityAcademic Institutions and Nonprofits only -
pDONR221_SLC8A1
Plasmid#132162PurposeGateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectorsDepositorInsertSLC8A1 (SLC8A1 Human)
UseTagsExpressionMammalianMutationPromoterAvailable sinceOct. 22, 2019AvailabilityIndustry, Academic Institutions, and Nonprofits -
mCherry-CRY2-P14P5K
Plasmid#79570Purposeexpression of mCherry-tagged CRY2PHR fused to iSH2 domain of mouse Pip5k1cDepositorInsertPip5k1c (Pip5k1c Mouse)
UseTagsCRY2 (photolyase homology region domain of Arabid…ExpressionMammalianMutationR445E and R446E; truncation of amino acids 636-66…PromoterCMVAvailable sinceAug. 9, 2016AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3-ALK2 Q207D
Plasmid#80871Purposemammalian expression of ALK2 Q207DDepositorInsertALK2 (ACVR1 Human)
UseTagsHAExpressionMammalianMutationQ207DPromoterCMVAvailable sinceOct. 11, 2016AvailabilityAcademic Institutions and Nonprofits only -
pF713-pEGFP-N1-Hs-FL-METTL20 wt
Plasmid#85114Purposetransfection of HeLa cell for transient expression of human full-length METTL20-EGFP fusionDepositorInserthuman full-length METTL20 (METTL20 Human)
UseTagsEGFPExpressionMammalianMutationPromoterCMVAvailable sinceNov. 12, 2018AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3-FLAG-mTET2 (N1041)
Plasmid#89737PurposeExpresses the N1041 truncation to mouse TET2 in mammalian cellsDepositorInsertTET2 (Tet2 Mouse)
UseTagsFlagExpressionMammalianMutationN-term 1041 truncation of mouse TET2 (contains fi…PromoterAvailable sinceMay 3, 2017AvailabilityAcademic Institutions and Nonprofits only -
pLKO_AU1.HSV.S_mCherry-NLS
Plasmid#178224PurposeNuclear Protein Barcode (nPC) for vector/cell tracking. Contains U6 trRNA cassette for sgRNA cloning. Enables spatial detection of CRISPR screens.DepositorInsertnPC Tagged mCherry-NLS
UseLentiviralTagsAU1.HSV.S and Nuclear Localization SignalExpressionMutationPromotereF1aAvailable sinceJan. 25, 2022AvailabilityAcademic Institutions and Nonprofits only -
RIP7-RLuc-YFP-pBS
Plasmid#72482PurposeExpresses a renilla luciferase-YFP fusion protein under control of the rat insulin 2 gene promoter (RIP7) suitable for transfection or generation of transgenic animalsDepositorInsertsUseLuciferaseTagseYFP and renilla luciferaseExpressionMammalianMutationeYFP varientPromoterAvailable sinceMarch 30, 2016AvailabilityAcademic Institutions and Nonprofits only -
3xFLAG-FKBP-LRRK2
Plasmid#193584PurposeExpresses human full-length LRRK2 with FKBP domain and 3xFLAG situated at the N-terminusDepositorInsertLeucine-rich repeat kinase 2 (LRRK2 Human)
UseTags3xFLAG and FKBPExpressionMammalianMutationPromoterCMVAvailable sinceJan. 17, 2023AvailabilityAcademic Institutions and Nonprofits only -
pDONR221_SLC22A31
Plasmid#132036PurposeGateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectorsDepositorInsertSLC22A31 (SLC22A31 Human)
UseTagsExpressionMammalianMutationPromoterAvailable sinceJan. 14, 2020AvailabilityIndustry, Academic Institutions, and Nonprofits