Addgene

We narrowed to 8,055 results for: sgRNA

Showing: 3941 - 3960 of 8055 results

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MARK1 gRNA (BRDN0001149223)

Plasmid

#77796

Purpose

3rd generation lentiviral gRNA plasmid targeting human MARK1

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MARK1 (MARK1 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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MARK4 gRNA (BRDN0001147387)

Plasmid

#76728

Purpose

3rd generation lentiviral gRNA plasmid targeting human MARK4

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MARK4 (MARK4 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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CD2 gRNA (BRDN0001146864)

Plasmid

#75827

Purpose

3rd generation lentiviral gRNA plasmid targeting human CD2

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CD2 (CD2 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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EIF2AK1 gRNA (BRDN0001148541)

Plasmid

#77049

Purpose

3rd generation lentiviral gRNA plasmid targeting human EIF2AK1

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

EIF2AK1 (EIF2AK1 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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FGFR3 gRNA (BRDN0001146639)

Plasmid

#75729

Purpose

3rd generation lentiviral gRNA plasmid targeting human FGFR3

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

FGFR3 (FGFR3 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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FGFR3 gRNA (BRDN0001147930)

Plasmid

#75730

Purpose

3rd generation lentiviral gRNA plasmid targeting human FGFR3

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

FGFR3 (FGFR3 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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CDK2 gRNA (BRDN0001147786)

Plasmid

#77192

Purpose

3rd generation lentiviral gRNA plasmid targeting human CDK2

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CDK2 (CDK2 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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pHR_UCOE-EF1a-dCas9-XTEN80-KRAB(Kox1)-IRES-mCherry

Plasmid

#188769

Purpose

dCas9 with a C-term HA-2xNLS-XTEN80(linker)-KRAB(Kox1)

Depositor

Jonathan Weissman, Marco Jost

Article

Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

Insert

dCas9-XTEN80-KRAB(Kox1)

Use

Lentiviral

Tags

HA-2xNLS-XTEN80(linker)-KRAB(Kox1)

Expression

Mutation

Promoter

EF1a

Available since

Oct. 19, 2022

Availability

Academic Institutions and Nonprofits only

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CAD gRNA (BRDN0001146638)

Plasmid

#76962

Purpose

3rd generation lentiviral gRNA plasmid targeting human CAD

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CAD (CAD Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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MERTK gRNA (BRDN0001146205)

Plasmid

#76446

Purpose

3rd generation lentiviral gRNA plasmid targeting human MERTK

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MERTK (MERTK Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
ATM gRNA (BRDN0001149033)

Plasmid

#77531

Purpose

3rd generation lentiviral gRNA plasmid targeting human ATM

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ATM (ATM Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
CDK12 gRNA (BRDN0001145847)

Plasmid

#75917

Purpose

3rd generation lentiviral gRNA plasmid targeting human CDK12

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CDK12 (CDK12 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
ATM gRNA (BRDN0001146099)

Plasmid

#77530

Purpose

3rd generation lentiviral gRNA plasmid targeting human ATM

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ATM (ATM Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
CDK9 gRNA (BRDN0001146478)

Plasmid

#77169

Purpose

3rd generation lentiviral gRNA plasmid targeting human CDK9

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CDK9 (CDK9 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
BTK gRNA (BRDN0001149473)

Plasmid

#77074

Purpose

3rd generation lentiviral gRNA plasmid targeting human BTK

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

BTK (BTK Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
EIF2AK3 gRNA (BRDN0001145848)

Plasmid

#77166

Purpose

3rd generation lentiviral gRNA plasmid targeting human EIF2AK3

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

EIF2AK3 (EIF2AK3 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
IGF1R gRNA (BRDN0001146028)

Plasmid

#76689

Purpose

3rd generation lentiviral gRNA plasmid targeting human IGF1R

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

IGF1R (IGF1R Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
pSin-EF2-DMD53-GFP

Plasmid

#138353

Purpose

Expressing a GFP reporter cassette, whose GFP reading frame is disrupted by insertion of partial DMD exon 53 sequences

Depositor

Baisong Lu

Article

Lyu et al PLoS One. 2020 Sep 24;15(9):e0239468. do

Insert

DMD exon 53 partial sequence to disrupt GFP reading frame (DMD Human)

Use

CRISPR and Lentiviral

Tags

No

Expression

Mammalian

Mutation

Promoter

EF2

Available since

Nov. 6, 2020

Availability

Academic Institutions and Nonprofits only

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FLT3 gRNA (BRDN0001145134)

Plasmid

#77350

Purpose

3rd generation lentiviral gRNA plasmid targeting human FLT3

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

FLT3 (FLT3 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
AKT2 gRNA (BRDN0001148949)

Plasmid

#77506

Purpose

3rd generation lentiviral gRNA plasmid targeting human AKT2

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

AKT2 (AKT2 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge