Immunology Research Plasmids and Resources
Mammalian organisms are exposed to millions of potential pathogens each day. Their ability to protect against infection depends on two systems that work in concert: the innate and adaptive immune systems.
Upon infection, the immune system triggers several processes to activate cells to recognize and get rid of infectious pathogens. The innate immune response is triggered within the first few minutes of exposure to a pathogen and is the dominant defense strategy during the first several days following exposure to a pathogen. The innate immune system is not specific to any particular pathogen. It includes physical barriers such as the skin and mucosa, antimicrobial peptides and proteins in the blood such as interferons and complement, and specialized cells such as macrophages and neutrophils that attack invading pathogens.
Innate immune cells also process and present foreign antigens to adaptive immune cells, such as T cells and B cells. About a week following the initial exposure to a pathogen, the adaptive immune response kicks in. The adaptive immune response is antigen-specific and includes cellular and humoral immunity. Once an adaptive immune cell is primed to recognize a specific antigen, it finds and attacks pathogens or infected cells expressing that antigen. Antibodies produced by B cells activate immune components that also lead to the destruction of pathogens. Over the course of an infection, adaptive immune cells will expand and give rise to memory cells that can recognize a recurrent infection and rapidly initiate a secondary immune response.
Browse Plasmids for Immunology Research
Genes have been grouped into tables based on the Gene Lists from Immport. Click the links below to go to the gene table for each category. The gene names in these tables link to the available plasmids for each gene. Please note that not all genes have plasmids available for request.
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Antigen Presentation | The cornerstone of the immune response is the recognition by T cells of foreign antigens on the surface of antigen presenting cells (APC) including dendritic cells and macrophages. Antigen presentation is mediated by the MHC class I and class II molecules found on the surface of APC. |
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BCR Signaling | B cells mediate humoral immunity through the secretion of antibodies, and also function as antigen presenting cells. B cells in secondary lymphoid organs recognize specific antigens through the B cell receptor (BCR). The strength and duration of signaling controls the fate of B cells and can lead to the formation of a high avidity BCR through repeat cycles of expansion. |
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Chemokines |
Chemokines, or chemotactic cytokines, are small proteins that can be secreted by immune cells and other cell types. They can be grouped in to the CC, CXC, XC, and CX3C families based on conserved cysteine residues. Chemokines recruit innate and adaptive immune cells to sites of inflammation throughout the body. |
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Cytokines |
Cytokines are molecules that enable cells of the immune system to communicate with each other across long distances. During infection and inflammation, the different cytokines that are released tailor the immune response to a specific trigger. |
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Interferons |
The interferon family of signaling proteins consists of Type I, Type II, and Type III interferons. They trigger the defensive responses of the immune system upon infection with virus and, like other cytokines, enable communication between cells of the immune system. |
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Interleukins |
Interleukins are cytokines that are secreted by immune cells and coordinate communication between immune cells over the course of an immune response. Over 60 interleukins have been described. |
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NK Cell Signaling | Natural killer (NK) cells can kill cells that have been infected by a foreign pathogen. They detect infected cells via receptors such as KIR and NKG2D. Upon activation, NK cells secrete perforin and granzyme B, two enzymes that create pores within an infected cell membrane, triggering cell death. |
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TCR Signaling | The T cell receptor (TCR) engages with antigen presenting cells of the innate immune system. Engagement of the TCR by an MHC molecule presenting its cognate antigen along with co-stimulation activates the T cell, whereas T cell tolerance or anergy are induced when the TCR is engaged without co-stimulation or with a low affinity antigen. |
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TGFbeta |
In the immune system, Tumour Growth Factor beta (TGFbeta) signaling and its downstream effector molecules, the Smad proteins, regulate the adaptive immune response through effects on numerous immune cell types including T cells and B cells. It also impacts the development and function of innate immune cells including NK cells, macrophages, dendritic cells, and granulocytes. |
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TLR | The toll like receptors (TLR) play a key role in the innate immune system. They are found on dendritic cells and macrophages and sense conserved microbial molecules during an infection. When TLRs sense a microbial pathogen, they trigger signalling pathways that lead to the activation of an immune response. |
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TNF |
The tumor necrosis factor (TNF) family of proteins are predominantly expressed by immune cells and help to regulate the immune response and inflammation. They act as cytokines when cleaved from the cell membrane and can also function as signaling proteins involved in proliferation, cell differentiation, and apoptosis. |
Plasmid Tables
The gene names in these tables link to the available plasmids for each gene. Please note that not all genes have plasmids available for request.
Antigen Processing and Presentation
The cornerstone of the immune response is the recognition by T cells of foreign antigens on the surface of antigen presenting cells (APC) including dendritic cells and macrophages. Antigen presentation is mediated by the MHC class I and class II molecules found on the surface of APC.
| Symbol | Name | Synonyms |
|---|---|---|
| ADRM1 | adhesion regulating molecule 1 | ARM1, GP110, MGC29536, Rpn13 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | ADTB3, ADTB3A, HPS, HPS2, PE |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | ZA2G, ZAG |
| B2M | beta-2-microglobulin | - |
| CALR | calreticulin | CRT, FLJ26680, RO, SSA, cC1qR |
| CANX | calnexin | CNX, FLJ26570, IP90, P90 |
| CD1A | CD1a molecule | CD1, FCB6, HTA1, R4, T6 |
| CD1B | CD1b molecule | CD1, CD1A, MGC125990, MGC125991, R1 |
| CD1C | CD1c molecule | BDCA1, CD1, CD1A, R7 |
| CD1D | CD1d molecule | CD1A, MGC34622, R3 |
| CD1E | CD1e molecule | CD1A, R2 |
| CD209 | CD209 molecule | CDSIGN, CLEC4L, DC-SIGN, DC-SIGN1, MGC129965 |
| CD4 | CD4 molecule | CD4mut |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | DHLAG, HLADG, Ia-GAMMA |
| CD8A | CD8a molecule | CD8, Leu2, MAL, p32 |
| CD8B | CD8b molecule | CD8B1, LYT3, Leu2, Ly3, MGC119115 |
| CIITA | class II, major histocompatibility complex, transactivator | C2TA, CIITAIV, MHC2TA, NLRA |
| CLEC4M | C-type lectin domain family 4, member M | CD209L, CD299, DC-SIGN2, DC-SIGNR, DCSIGNR, HP10347, L-SIGN, LSIGN, MGC129964, MGC47866 |
| CREB1 | cAMP responsive element binding protein 1 | CREB, MGC9284 |
| CTSB | cathepsin B | APPS, CPSB |
| CTSE | cathepsin E | CATE |
| CTSL1 | cathepsin L1 | CATL, CTSL, FLJ31037, MEP |
| CTSS | cathepsin S | MGC3886 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 | A-LAP, ALAP, APPILS, ARTS-1, ARTS1, ERAAP, ERAAP1, KIAA0525, PILS-AP, PILSAP |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | FLJ23633, FLJ23701, FLJ23807, L-RAP, LRAP |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | FCRG |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha | FCRN, alpha-chain |
| HFE | hemochromatosis | HFE1, HH, HLA-H, MGC103790, MVCD7, dJ221C16.10.1 |
| HLA-A | major histocompatibility complex, class I, A | FLJ26655, HLAA |
| HLA-B | major histocompatibility complex, class I, B | AS, HLA-B-7301, HLA-B73, HLAB, HLAC, MGC111087, SPDA1 |
| HLA-C | major histocompatibility complex, class I, C | D6S204, FLJ27082, HLA-Cw, HLA-Cw12, HLA-JY3, HLC-C, PSORS1 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | D6S222E, DMA, HLADM, RING6 |
| HLA-DMB | major histocompatibility complex, class II, DM beta | D6S221E, RING7 |
| HLA-DOA | major histocompatibility complex, class II, DO alpha | HLA-DNA, HLA-DZA, HLADZ |
| HLA-DOB | major histocompatibility complex, class II, DO beta | DOB |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | HLA-DP1A, HLADP, HLASB |
| HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 | DPB1, HLA-DP1B |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | CD, CELIAC1, DQ-A1, FLJ27088, FLJ27328, GSE, HLA-DQA, MGC149527 |
| HLA-DQA2 | major histocompatibility complex, class II, DQ alpha 2 | HLA-DXA |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 | CELIAC1, HLA-DQB, IDDM1 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | HLA-DRA1 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | DRB1, FLJ75017, FLJ76359, HLA-DR1B, HLA-DRB, HLA-DRB1*, SS1 |
| HLA-DRB3 | major histocompatibility complex, class II, DR beta 3 | HLA-DR3B, HLA-DR52, MGC117330 |
| HLA-DRB4 | major histocompatibility complex, class II, DR beta 4 | DRB4, HLA-DR4B |
| HLA-DRB5 | major histocompatibility complex, class II, DR beta 5 | FLJ76359, HLA-DRB |
| HLA-E | major histocompatibility complex, class I, E | DKFZp686P19218, EA1.2, EA2.1, HLA-6.2, MHC, QA1 |
| HLA-F | major histocompatibility complex, class I, F | CDA12, HLA-5.4, HLA-CDA12, HLAF |
| HLA-G | major histocompatibility complex, class I, G | MHC-G |
| HLA-H | major histocompatibility complex, class I, H (pseudogene) | HLAHP |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | FLJ31884, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | D6S182, FLJ26984, HSP90-BETA, HSP90B, HSPC2, HSPCB |
| HSPA1A | heat shock 70kDa protein 1A | FLJ54303, FLJ54370, FLJ54392, FLJ54408, FLJ75127, HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1, HSPA1B |
| HSPA1B | heat shock 70kDa protein 1B | FLJ54328, HSP70-1B, HSP70-2, HSPA1A |
| HSPA1L | heat shock 70kDa protein 1-like | HSP70-1L, HSP70-HOM, HSP70T, hum70t |
| HSPA2 | heat shock 70kDa protein 2 | HSP70-2, HSP70-3 |
| HSPA4 | heat shock 70kDa protein 4 | APG-2, HS24/P52, MGC131852, RY, hsp70, hsp70RY |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | BIP, FLJ26106, GRP78, MIF2 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | - |
| HSPA8 | heat shock 70kDa protein 8 | HSC54, HSC70, HSC71, HSP71, HSP73, HSPA10, LAP1, MGC131511, MGC29929, NIP71 |
| ICAM1 | intercellular adhesion molecule 1 | BB2, CD54, P3.58 |
| IFI30 | interferon, gamma-inducible protein 30 | GILT, IFI-30, IP30, MGC32056 |
| IFNA1 | interferon, alpha 1 | IFL, IFN, IFN-ALPHA, IFNA13, IFNA@, MGC138207, MGC138505, MGC138507 |
| IFNA10 | interferon, alpha 10 | MGC119878, MGC119879 |
| IFNA13 | interferon, alpha 13 | - |
| IFNA14 | interferon, alpha 14 | LEIF2H, MGC125756, MGC125757 |
| IFNA16 | interferon, alpha 16 | - |
| IFNA17 | interferon, alpha 17 | IFNA, INFA, LEIF2C1 |
| IFNA2 | interferon, alpha 2 | IFNA, INFA2, MGC125764, MGC125765 |
| IFNA21 | interferon, alpha 21 | MGC126687, MGC126689 |
| IFNA4 | interferon, alpha 4 | INFA4, MGC142200 |
| IFNA5 | interferon, alpha 5 | INFA5 |
| IFNA6 | interferon, alpha 6 | - |
| IFNA7 | interferon, alpha 7 | IFNA-J |
| IFNA8 | interferon, alpha 8 | - |
| IFNG | interferon, gamma | IFG, IFI |
| KIAA0368 | KIAA0368 | ECM29, FLJ22036, KIAA1962, RP11-386D8.2 |
| KIR2DL1 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 | CD158A, KIR-K64, KIR221, NKAT, NKAT1, p58.1 |
| KIR2DL2 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 | CD158B1, CD158b, NKAT6, p58.2 |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 | CD158B2, CD158b, GL183, KIR-023GB, KIR-K7b, KIR-K7c, KIRCL23, MGC129943, NKAT, NKAT2, NKAT2A, NKAT2B, p58 |
| KIR2DL4 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 | CD158D, G9P, KIR103, KIR103AS |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A | CD158F, KIR2DL5, KIR2DL5.1, KIR2DL5.3 |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 | CD158H, CD158a, p50.1 |
| KIR2DS3 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3 | NKAT7 |
| KIR2DS4 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 | CD158I, KIR1D, KIR412, KKA3, MGC120019, MGC125315, MGC125317, NKAT8 |
| KIR2DS5 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5 | CD158G, NKAT9 |
| KIR3DL1 | killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 | CD158E1, KIR, MGC119726, MGC119728, MGC126589, MGC126591, NKAT3, NKB1, NKB1B |
| KIR3DL2 | killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 | CD158K, MGC125321, NKAT4, NKAT4B, p140 |
| KIR3DL3 | killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 | CD158Z, KIR3DL7, KIR44, KIRC1 |
| KLRC1 | killer cell lectin-like receptor subfamily C, member 1 | CD159A, MGC13374, MGC59791, NKG2, NKG2A |
| KLRC2 | killer cell lectin-like receptor subfamily C, member 2 | CD159c, MGC138244, NKG2-C, NKG2C |
| KLRC3 | killer cell lectin-like receptor subfamily C, member 3 | NKG2-E, NKG2E |
| KLRC4 | killer cell lectin-like receptor subfamily C, member 4 | FLJ17759, FLJ78582, NKG2-F, NKG2F |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | CD94 |
| LGMN | legumain | AEP, LGMN1, PRSC1 |
| LTA | lymphotoxin alpha (TNF superfamily, member 1) | LT, TNFB, TNFSF1 |
| MICA | MHC class I polypeptide-related sequence A | FLJ60820, MGC111087, PERB11.1 |
| MICB | MHC class I polypeptide-related sequence B | PERB11.2 |
| MR1 | major histocompatibility complex, class I-related | HLALS |
| NFYA | nuclear transcription factor Y, alpha | CBF-A, CBF-B, FLJ11236, HAP2, NF-YA |
| NFYB | nuclear transcription factor Y, beta | CBF-A, CBF-B, HAP3, NF-YB |
| NFYC | nuclear transcription factor Y, gamma | CBF-C, CBFC, DKFZp667G242, FLJ45775, H1TF2A, HAP5, HSM, NF-YC |
| PDIA2 | protein disulfide isomerase family A, member 2 | PDA2, PDI, PDIP, PDIR |
| PDIA3 | protein disulfide isomerase family A, member 3 | ER60, ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC |
| PROCR | protein C receptor, endothelial (EPCR) | CCCA, CCD41, CD201, EPCR, MGC23024, bA42O4.2 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | D6S216, D6S216E, LMP7, MGC1491, PSMB5i, RING10, beta5i |
| PSMC1 | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | MGC24583, MGC8541, P26S4, S4, p56 |
| PSMC2 | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | MGC3004, MSS1, Nbla10058, S7 |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | MGC8487, TBP1 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | MGC13687, MGC23214, MGC8570, MIP224, S6, TBP7 |
| PSMC5 | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | S8, SUG-1, SUG1, TBP10, TRIP1, p45, p45/SUG |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | CADP44, MGC12520, P44, SUG2, p42 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | MGC133040, MGC133041, P112, Rpn2, S1 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | dJ889N15.2, p28 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | MGC3844, Rpn6, S9, p44.5 |
| PSMD13 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | HSPC027, Rpn9, S11, p40.5 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | PAD1, POH1, rpn11 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | MGC14274, P97, Rpn1, S2, TRAP2 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | P58, RPN3, S3 |
| PSMD4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | AF, AF-1, ASF, MCB1, Rpn10, S5A, pUB-R5 |
| PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 | KIAA0072, MGC23145, S5B |
| PSMD6 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | KIAA0107, Rpn7, S10, SGA-113M, p44S10 |
| PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 | MOV34, P40, Rpn8, S12 |
| PSMD8 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | HIP6, HYPF, MGC1660, Nin1p, Rpn12, S14, p31 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | IFI5111, MGC8628, PA28A, PA28alpha, REGalpha |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | IFI5111, MGC8628, PA28A, PA28alpha, REGalpha |
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | PA28B, PA28beta, REGbeta |
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | PA28B, PA28beta, REGbeta |
| PSME3 | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) | Ki, PA28-gamma, PA28G, REG-GAMMA |
| RAET1E | retinoic acid early transcript 1E | LETAL, MGC125308, MGC125309, RAET1E2, ULBP4, bA350J20.7 |
| RAET1G | retinoic acid early transcript 1G | ULBP5 |
| RAET1L | retinoic acid early transcript 1L | - |
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | I-REL, IREL |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) | - |
| RFXANK | regulatory factor X-associated ankyrin-containing protein | ANKRA1, BLS, F14150_1, MGC138628, RFX-B |
| RFXAP | regulatory factor X-associated protein | - |
| SHFM1 | split hand/foot malformation (ectrodactyly) type 1 | DSS1, ECD, SEM1, SHFD1, SHSF1, Shfdg1 |
| SLC10A2 | solute carrier family 10 (sodium/bile acid cotransporter family), member 2 | ASBT, ISBT, NTCP2 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | ABC17, ABCB2, APT1, D6S114E, FLJ26666, FLJ41500, PSF1, RING4, TAP1*0102N, TAP1N |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | ABC18, ABCB3, APT2, D6S217E, PSF2, RING11 |
| TAPBP | TAP binding protein (tapasin) | NGS17, TAPA, TPN, TPSN, tapasin |
| TAPBPL | TAP binding protein-like | FLJ10143, TAPBP-R, TAPBPR |
| THBS1 | thrombospondin 1 | THBS, THBS-1, TSP, TSP-1, TSP1 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | C20orf188, TRRP4AP, TRUSS |
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | JBS, MGC142065, MGC142067 |
| UBXN1 | UBX domain protein 1 | 2B28, UBXD10 |
| ULBP1 | UL16 binding protein 1 | RAET1I |
| ULBP2 | UL16 binding protein 2 | N2DL2, RAET1H |
| ULBP3 | UL16 binding protein 3 | RAET1N |
BCR Signaling
B cells mediate humoral immunity through the secretion of antibodies, and also function as antigen presenting cells. B cells in secondary lymphoid organs recognize specific antigens through the B cell receptor (BCR). The strength and duration of signaling controls the fate of B cells and can lead to the formation of a high avidity BCR through repeat cycles of expansion.
| Symbol | Name | Synonyms |
|---|---|---|
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | PKBB, PKBBETA, PRKBB, RAC-BETA |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) | DKFZp434N0250, PKB-GAMMA, PKBG, PRKBG, RAC-PK-gamma, RAC-gamma, STK-2 |
| BCL10 | B-cell CLL/lymphoma 10 | CARMEN, CIPER, CLAP, c-E10, mE10 |
| BLNK | B-cell linker | BASH, BLNK-S, LY57, MGC111051, SLP-65, SLP65 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | AGMX1, AT, ATK, BPK, IMD1, MGC126261, MGC126262, PSCTK1, XLA |
| CARD11 | caspase recruitment domain family, member 11 | BIMP3, CARMA1, MGC133069 |
| CD19 | CD19 molecule | B4, MGC12802 |
| CD22 | CD22 molecule | FLJ22814, MGC130020, SIGLEC-2, SIGLEC2 |
| CD72 | CD72 molecule | CD72b, LYB2 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | IGA, MB-1 |
| CD79B | CD79b molecule, immunoglobulin-associated beta | B29, IGB |
| CD81 | CD81 molecule | S5.7, TAPA1, TSPAN28 |
| CHP | calcium binding protein P22 | SLC9A1BP |
| CHP2 | calcineurin B homologous protein 2 | - |
| CHUK | conserved helix-loop-helix ubiquitous kinase | IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16 |
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | C3DR, CD21, SLEB9 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | CD32, CD32B, FCG2, FCGR2, IGFR2 |
| FOS | v-fos FBJ murine osteosarcoma viral oncogene homolog | AP-1, C-FOS |
| GSK3B | glycogen synthase kinase 3 beta | - |
| HRAS | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1 |
| IFITM1 | interferon induced transmembrane protein 1 (9-27) | 9-27, CD225, IFI17, LEU13 |
| IGH@ | immunoglobulin heavy locus | DKFZp686C15213, IGH, IGH.1@, IGHDY1, MGC72071, MGC88774 |
| IGHA1 | immunoglobulin heavy constant alpha 1 | FLJ14473, FLJ35065, FLJ35500, FLJ36402, FLJ39698, FLJ40001, FLJ41548, FLJ41552, FLJ41789, FLJ43248, FLJ43594, FLJ44293, FLJ46028, FLJ46621, FLJ46724, FLJ46811, FLJ46824, FLJ90170, IgA1, MGC102857 |
| IGHA2 | immunoglobulin heavy constant alpha 2 (A2m marker) | - |
| IGHD | immunoglobulin heavy constant delta | FLJ00382, FLJ46727, MGC29633 |
| IGHD@ | immunoglobulin heavy diversity group | IGD1, IGHDY1 |
| IGHD1-1 | immunoglobulin heavy diversity 1-1 | IGHD11 |
| IGHD1-14 | immunoglobulin heavy diversity 1-14 (non-functional) | DM2, IGHD114 |
| IGHD1-20 | immunoglobulin heavy diversity 1-20 | IGHD120 |
| IGHD1-26 | immunoglobulin heavy diversity 1-26 | IGHD126 |
| IGHD1-7 | immunoglobulin heavy diversity 1-7 | DM1, IGHD17 |
| IGHD2-15 | immunoglobulin heavy diversity 2-15 | D2, IGHD215 |
| IGHD2-2 | immunoglobulin heavy diversity 2-2 | IGHD22 |
| IGHD2-21 | immunoglobulin heavy diversity 2-21 | IGHD221 |
| IGHD2-8 | immunoglobulin heavy diversity 2-8 | DLR1, IGHD28 |
| IGHD3-10 | immunoglobulin heavy diversity 3-10 | DXP'1, IGHD310 |
| IGHD3-16 | immunoglobulin heavy diversity 3-16 | IGHD316 |
| IGHD3-22 | immunoglobulin heavy diversity 3-22 | IGHD322 |
| IGHD3-3 | immunoglobulin heavy diversity 3-3 | DXP4, IGHD33 |
| IGHD3-9 | immunoglobulin heavy diversity 3-9 | DXP1, IGHD39 |
| IGHD4-11 | immunoglobulin heavy diversity 4-11 (non-functional) | DA1, IGHD411 |
| IGHD4-17 | immunoglobulin heavy diversity 4-17 | IGHD417 |
| IGHD4-23 | immunoglobulin heavy diversity 4-23 (non-functional) | IGHD423 |
| IGHD4-4 | immunoglobulin heavy diversity 4-4 | DA4, IGHD44 |
| IGHD5-12 | immunoglobulin heavy diversity 5-12 | DK1, IGHD512 |
| IGHD5-18 | immunoglobulin heavy diversity 5-18 | IGHD518 |
| IGHD5-24 | immunoglobulin heavy diversity 5-24 (non-functional) | IGHD524 |
| IGHD5-5 | immunoglobulin heavy diversity 5-5 | DK4, IGHD55 |
| IGHD6-13 | immunoglobulin heavy diversity 6-13 | DN1, IGHD613 |
| IGHD6-19 | immunoglobulin heavy diversity 6-19 | IGHD619 |
| IGHD6-25 | immunoglobulin heavy diversity 6-25 | IGHD625 |
| IGHD6-6 | immunoglobulin heavy diversity 6-6 | D(N4), IGHD66 |
| IGHD7-27 | immunoglobulin heavy diversity 7-27 | DHQ52, IGHD727 |
| IGHE | immunoglobulin heavy constant epsilon | IgE |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) | - |
| IGHG2 | immunoglobulin heavy constant gamma 2 (G2m marker) | DKFZp686I04196 |
| IGHG3 | immunoglobulin heavy constant gamma 3 (G3m marker) | DKFZp686H11213, FLJ39988, FLJ40036, FLJ40253, FLJ40587, FLJ40789, FLJ40834, IgG3, MGC45809 |
| IGHG4 | immunoglobulin heavy constant gamma 4 (G4m marker) | MGC117419 |
| IGHJ@ | immunoglobulin heavy joining group | IGHJ |
| IGHJ1 | immunoglobulin heavy joining 1 | JH1 |
| IGHJ2 | immunoglobulin heavy joining 2 | JH2 |
| IGHJ3 | immunoglobulin heavy joining 3 | JH3b |
| IGHJ4 | immunoglobulin heavy joining 4 | JH4b |
| IGHJ5 | immunoglobulin heavy joining 5 | JH5b |
| IGHJ6 | immunoglobulin heavy joining 6 | JH6b |
| IGHM | immunoglobulin heavy constant mu | DKFZp686I15196, DKFZp686I15212, FLJ00385, MGC104996, MGC52291, MU, VH |
| IGHV@ | immunoglobulin heavy variable group | IGHV |
| IGHV1-18 | immunoglobulin heavy variable 1-18 | IGHV118 |
| IGHV1-2 | immunoglobulin heavy variable 1-2 | IGHV12 |
| IGHV1-24 | immunoglobulin heavy variable 1-24 | IGHV124, VH |
| IGHV1-3 | immunoglobulin heavy variable 1-3 | IGHV13 |
| IGHV1-45 | immunoglobulin heavy variable 1-45 | IGHV145, VH |
| IGHV1-46 | immunoglobulin heavy variable 1-46 | IGHV146 |
| IGHV1-58 | immunoglobulin heavy variable 1-58 | IGHV158, VH |
| IGHV1-69 | immunoglobulin heavy variable 1-69 | IGHV1-E, IGHV169, IGHV1E |
| IGHV1-8 | immunoglobulin heavy variable 1-8 | IGHV18 |
| IGHV1-C | immunoglobulin heavy variable 1-C (provisional, non-functional) | IGHV1C |
| IGHV1-F | immunoglobulin heavy variable 1-F (provisional) | IGHV1F |
| IGHV2-26 | immunoglobulin heavy variable 2-26 | IGHV226, VH |
| IGHV2-5 | immunoglobulin heavy variable 2-5 | IGHV25, VH |
| IGHV2-70 | immunoglobulin heavy variable 2-70 | IGHV270, VH |
| IGHV3-11 | immunoglobulin heavy variable 3-11 (gene/pseudogene) | IGHV311, VH |
| IGHV3-13 | immunoglobulin heavy variable 3-13 | IGHV313 |
| IGHV3-15 | immunoglobulin heavy variable 3-15 | IGHV315, VH |
| IGHV3-16 | immunoglobulin heavy variable 3-16 (non-functional) | IGHV316, VH |
| IGHV3-20 | immunoglobulin heavy variable 3-20 | IGHV320, VH |
| IGHV3-21 | immunoglobulin heavy variable 3-21 | IGHV321, VH |
| IGHV3-23 | immunoglobulin heavy variable 3-23 | DP47, IGHV323, V3-23, VH26 |
| IGHV3-30 | immunoglobulin heavy variable 3-30 | IGHV330, VH |
| IGHV3-30-3 | immunoglobulin heavy variable 3-30-3 | IGHV3-3, IGHV3303 |
| IGHV3-30-5 | immunoglobulin heavy variable 3-30-5 | IGHV3-3, IGHV3305 |
| IGHV3-33 | immunoglobulin heavy variable 3-33 | IGHV333, VH |
| IGHV3-35 | immunoglobulin heavy variable 3-35 (non-functional) | IGHV335, VH |
| IGHV3-38 | immunoglobulin heavy variable 3-38 (non-functional) | IGHV338, VH |
| IGHV3-43 | immunoglobulin heavy variable 3-43 | IGHV343, VH |
| IGHV3-48 | immunoglobulin heavy variable 3-48 | IGHV348, VH |
| IGHV3-49 | immunoglobulin heavy variable 3-49 | IGHV349, VH |
| IGHV3-53 | immunoglobulin heavy variable 3-53 | IGHV353, VH |
| IGHV3-64 | immunoglobulin heavy variable 3-64 | IGHV364, VH |
| IGHV3-66 | immunoglobulin heavy variable 3-66 | IGHV366, VH |
| IGHV3-7 | immunoglobulin heavy variable 3-7 | IGHV37, VH |
| IGHV3-72 | immunoglobulin heavy variable 3-72 | IGHV372, VH |
| IGHV3-73 | immunoglobulin heavy variable 3-73 | IGHV373, VH |
| IGHV3-74 | immunoglobulin heavy variable 3-74 | IGHV374, VH |
| IGHV3-9 | immunoglobulin heavy variable 3-9 | IGHV39, VH |
| IGHV3-D | immunoglobulin heavy variable 3-D (provisional) | IGHV3D |
| IGHV3-H | immunoglobulin heavy variable 3-H pseudogene (provisional) | IGHV3H |
| IGHV4-28 | immunoglobulin heavy variable 4-28 | IGHV428, VH |
| IGHV4-30-1 | immunoglobulin heavy variable 4-30-1 | IGHV4-3 |
| IGHV4-30-2 | immunoglobulin heavy variable 4-30-2 | IGHV4-3, IGHV4302 |
| IGHV4-30-4 | immunoglobulin heavy variable 4-30-4 | IGHV4-3, IGHV4304 |
| IGHV4-31 | immunoglobulin heavy variable 4-31 | FLJ45507, IGHV431 |
| IGHV4-34 | immunoglobulin heavy variable 4-34 | IGHV434, VH |
| IGHV4-39 | immunoglobulin heavy variable 4-39 | IGHV439, VH |
| IGHV4-4 | immunoglobulin heavy variable 4-4 | IGHV44, VH |
| IGHV4-59 | immunoglobulin heavy variable 4-59 | IGHV459, VH |
| IGHV4-61 | immunoglobulin heavy variable 4-61 | IGHV461, VH |
| IGHV4-B | immunoglobulin heavy variable 4-B (provisional) | IGHV4B |
| IGHV5-51 | immunoglobulin heavy variable 5-51 | IGHV551, VH |
| IGHV5-A | immunoglobulin heavy variable 5-A (provisional, gene/pseudogene) | IGHV5A |
| IGHV6-1 | immunoglobulin heavy variable 6-1 | IGHV61, VH |
| IGHV7-4-1 | immunoglobulin heavy variable 7-4-1 | IGHV7-41, IGHV741 |
| IGHV7-81 | immunoglobulin heavy variable 7-81 (non-functional) | IGHV781 |
| IGK@ | immunoglobulin kappa locus | FLJ26296, IGK, IGKC, MGC22645, MGC27376, MGC40426, MGC71990 |
| IGKC | immunoglobulin kappa constant | HCAK1, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809 |
| IGKDEL | immunoglobulin kappa deleting element or like | IGKDE |
| IGKJ@ | immunoglobulin kappa joining group | IGKJ |
| IGKJ1 | immunoglobulin kappa joining 1 | J1 |
| IGKJ2 | immunoglobulin kappa joining 2 | J2 |
| IGKJ3 | immunoglobulin kappa joining 3 | J3 |
| IGKJ4 | immunoglobulin kappa joining 4 | J4 |
| IGKJ5 | immunoglobulin kappa joining 5 | J5 |
| IGKV@ | immunoglobulin kappa variable group | IGKV, IGKV1, IGKV1@, IGKV2, IGKV2@, IGKV3, IGKV3@ |
| IGKV1-12 | immunoglobulin kappa variable 1-12 | IGKV112, L19 |
| IGKV1-13 | immunoglobulin kappa variable 1-13 (gene/pseudogene) | IGKV113, L18 |
| IGKV1-16 | immunoglobulin kappa variable 1-16 | IGKV116, L1 |
| IGKV1-17 | immunoglobulin kappa variable 1-17 | A30, IGKV117 |
| IGKV1-27 | immunoglobulin kappa variable 1-27 | A20, IGKV127 |
| IGKV1-33 | immunoglobulin kappa variable 1-33 | IGKV133, O18 |
| IGKV1-37 | immunoglobulin kappa variable 1-37 (non-functional) | IGKV137, O14 |
| IGKV1-39 | immunoglobulin kappa variable 1-39 (gene/pseudogene) | IGKV139, O12, O12a |
| IGKV1-5 | immunoglobulin kappa variable 1-5 | IGKV, IGKV15, L12, L12a, MGC22745, MGC32715, MGC88810, V1 |
| IGKV1-6 | immunoglobulin kappa variable 1-6 | IGKV16, L11 |
| IGKV1-8 | immunoglobulin kappa variable 1-8 | IGKV18, L9 |
| IGKV1-9 | immunoglobulin kappa variable 1-9 | IGKV19, L8 |
| IGKV1D-12 | immunoglobulin kappa variable 1D-12 | IGKV1D12, L19 |
| IGKV1D-13 | immunoglobulin kappa variable 1D-13 | IGKV1D13, L18 |
| IGKV1D-16 | immunoglobulin kappa variable 1D-16 | IGKV1D16, L15, L15a |
| IGKV1D-17 | immunoglobulin kappa variable 1D-17 | IGKV1D17, L14 |
| IGKV1D-33 | immunoglobulin kappa variable 1D-33 | IGKV1D33, O8 |
| IGKV1D-37 | immunoglobulin kappa variable 1D-37 (non-functional) | IGKV1D37, O4 |
| IGKV1D-39 | immunoglobulin kappa variable 1D-39 | IGKV1D39, O2 |
| IGKV1D-42 | immunoglobulin kappa variable 1D-42 (non-functional) | IGKV1D42, L22 |
| IGKV1D-43 | immunoglobulin kappa variable 1D-43 | IGKV1D43, L23, L23a |
| IGKV1D-8 | immunoglobulin kappa variable 1D-8 | IGKV1D8, L24, L24a |
| IGKV2-24 | immunoglobulin kappa variable 2-24 | A23, IGKV224 |
| IGKV2-28 | immunoglobulin kappa variable 2-28 | A19, IGKV228 |
| IGKV2-30 | immunoglobulin kappa variable 2-30 | A17, IGKV230 |
| IGKV2-40 | immunoglobulin kappa variable 2-40 | IGKV240, O11, O11a |
| IGKV2D-24 | immunoglobulin kappa variable 2D-24 (non-functional) | A7, IGKV2D24 |
| IGKV2D-28 | immunoglobulin kappa variable 2D-28 | A3, IGKV2D28 |
| IGKV2D-29 | immunoglobulin kappa variable 2D-29 | A2a, A2c, IGKV2D29 |
| IGKV2D-30 | immunoglobulin kappa variable 2D-30 | A1, IGKV2D30 |
| IGKV2D-40 | immunoglobulin kappa variable 2D-40 | IGKV2D40, O1 |
| IGKV3-11 | immunoglobulin kappa variable 3-11 | IGKV311, L6 |
| IGKV3-15 | immunoglobulin kappa variable 3-15 | IGKV315, L2 |
| IGKV3-20 | immunoglobulin kappa variable 3-20 | 13K18, A27, IGKV320 |
| IGKV3-7 | immunoglobulin kappa variable 3-7 (non-functional) | IGKV37, L10, L10a, Vh |
| IGKV3D-11 | immunoglobulin kappa variable 3D-11 | IGKV3D11, L20 |
| IGKV3D-15 | immunoglobulin kappa variable 3D-15 (gene/pseudogene) | IGKV3D15, L16, L16a, L16b, L16c |
| IGKV3D-20 | immunoglobulin kappa variable 3D-20 | A11, A11a, IGKV3D20 |
| IGKV3D-7 | immunoglobulin kappa variable 3D-7 | IGKV3D7, L25 |
| IGKV4-1 | immunoglobulin kappa variable 4-1 | B3, IGKV41 |
| IGKV5-2 | immunoglobulin kappa variable 5-2 | B2, IGKV52 |
| IGKV6-21 | immunoglobulin kappa variable 6-21 (non-functional) | A26, IGKV621 |
| IGKV6D-21 | immunoglobulin kappa variable 6D-21 (non-functional) | A10, IGKV6D21 |
| IGKV6D-41 | immunoglobulin kappa variable 6D-41 (non-functional) | A14 |
| IGL@ | immunoglobulin lambda locus | IGL, MGC88804 |
| IGLC1 | immunoglobulin lambda constant 1 (Mcg marker) | IGLC |
| IGLC2 | immunoglobulin lambda constant 2 (Kern-Oz- marker) | IGLC, MGC20392, MGC45681 |
| IGLC3 | immunoglobulin lambda constant 3 (Kern-Oz+ marker) | IGLC |
| IGLC6 | immunoglobulin lambda constant 6 (Kern+Oz- marker, gene/pseudogene) | IGLC |
| IGLC7 | immunoglobulin lambda constant 7 | C7 |
| IGLJ@ | immunoglobulin lambda joining group | IGLJ |
| IGLJ1 | immunoglobulin lambda joining 1 | J1 |
| IGLJ2 | immunoglobulin lambda joining 2 | J2 |
| IGLJ3 | immunoglobulin lambda joining 3 | J3 |
| IGLJ4 | immunoglobulin lambda joining 4 (non-functional) | - |
| IGLJ5 | immunoglobulin lambda joining 5 (non-functional) | - |
| IGLJ6 | immunoglobulin lambda joining 6 | - |
| IGLJ7 | immunoglobulin lambda joining 7 | J7 |
| IGLV@ | immunoglobulin lambda variable group | IGLV |
| IGLV1-36 | immunoglobulin lambda variable 1-36 | IGLV136, V1-11 |
| IGLV1-40 | immunoglobulin lambda variable 1-40 | IGLV140, V1-13 |
| IGLV1-44 | immunoglobulin lambda variable 1-44 | IGLV144, V1-16 |
| IGLV1-47 | immunoglobulin lambda variable 1-47 | IGLV147, V1-17 |
| IGLV1-50 | immunoglobulin lambda variable 1-50 (non-functional) | IGLV150, V1-18 |
| IGLV1-51 | immunoglobulin lambda variable 1-51 | IGLV151, V1-19 |
| IGLV10-54 | immunoglobulin lambda variable 10-54 | IGLV1054, V1-20 |
| IGLV11-55 | immunoglobulin lambda variable 11-55 (non-functional) | IGLV1155, V4-6 |
| IGLV2-11 | immunoglobulin lambda variable 2-11 | IGLV211, V1-3 |
| IGLV2-14 | immunoglobulin lambda variable 2-14 | IGLV214, V1-4 |
| IGLV2-18 | immunoglobulin lambda variable 2-18 | IGLV218, V1-5 |
| IGLV2-23 | immunoglobulin lambda variable 2-23 | IGLV223, V1-7 |
| IGLV2-33 | immunoglobulin lambda variable 2-33 (non-functional) | IGLV233, V1-9 |
| IGLV2-8 | immunoglobulin lambda variable 2-8 | IGLV28, V1-2 |
| IGLV3-1 | immunoglobulin lambda variable 3-1 | IGLV31, V2-1 |
| IGLV3-10 | immunoglobulin lambda variable 3-10 | IGLV310, V2-7 |
| IGLV3-12 | immunoglobulin lambda variable 3-12 | IGLV312, V2-8 |
| IGLV3-16 | immunoglobulin lambda variable 3-16 | IGLV316, V2-11 |
| IGLV3-19 | immunoglobulin lambda variable 3-19 | IGLV319, V2-13, VL3L |
| IGLV3-21 | immunoglobulin lambda variable 3-21 | IGLV321, V2-14 |
| IGLV3-22 | immunoglobulin lambda variable 3-22 (gene/pseudogene) | IGLV322, V2-15 |
| IGLV3-25 | immunoglobulin lambda variable 3-25 | IGLV325, MGC105005, V2-17 |
| IGLV3-27 | immunoglobulin lambda variable 3-27 | IGLV327, V2-19 |
| IGLV3-32 | immunoglobulin lambda variable 3-32 (non-functional) | IGLV332, V2-23P |
| IGLV3-9 | immunoglobulin lambda variable 3-9 (gene/pseudogene) | IGLV39, V2-6 |
| IGLV4-3 | immunoglobulin lambda variable 4-3 | IGLV43, V5-1 |
| IGLV4-60 | immunoglobulin lambda variable 4-60 | IGLV460, V5-4 |
| IGLV4-69 | immunoglobulin lambda variable 4-69 | IGLV469, V5-6 |
| IGLV5-37 | immunoglobulin lambda variable 5-37 | IGLV537, V4-1 |
| IGLV5-39 | immunoglobulin lambda variable 5-39 | IGLV539 |
| IGLV5-45 | immunoglobulin lambda variable 5-45 | IGLV545, V4-2 |
| IGLV5-48 | immunoglobulin lambda variable 5-48 (non-functional) | IGLV548, V4-3 |
| IGLV5-52 | immunoglobulin lambda variable 5-52 | IGLV552, V4-4 |
| IGLV6-57 | immunoglobulin lambda variable 6-57 | IGLV657, MGC34845, V1-22 |
| IGLV7-43 | immunoglobulin lambda variable 7-43 | IGLV743, V3-2 |
| IGLV7-46 | immunoglobulin lambda variable 7-46 (gene/pseudogene) | IGLV746, V3-3 |
| IGLV8-61 | immunoglobulin lambda variable 8-61 | IGLV861, V3-4 |
| IGLV9-49 | immunoglobulin lambda variable 9-49 | IGLV949, V5-2 |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | FLJ40509, IKK-beta, IKK2, IKKB, MGC131801, NFKBIKB |
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | AMCBX1, FIP-3, FIP3, Fip3p, IKK-gamma, IP, IP1, IP2, IPD2, NEMO |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | MGC104855, MGC142140, MGC142142, SHIP, SHIP1, SIP-145, hp51CN |
| JUN | jun oncogene | AP-1, AP1, c-Jun |
| KRAS | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS3, RASK2 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 | CD85A, HL9, ILT5, LIR-3, LIR3, MGC138403, PIRB |
| LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | FLJ26625, JTK8 |
| MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | DKFZp434L132, MLT, MLT1 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | KIAA0827, NF-AT5, NFATL1, NFATZ, OREBP, TONEBP |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 | MGC138448, NF-ATC, NFAT2, NFATc |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | NFAT1, NFATP |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | NFAT4, NFATX |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | NF-ATc4, NFAT3 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | DKFZp686C01211, EBP-1, KBF1, MGC54151, NF-kappa-B, NFKB-p105, NFKB-p50, p105, p50 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | IKBA, MAD-3, NFKBI |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | IKBB, TRIP9 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | IKBE |
| NRAS | neuroblastoma RAS viral (v-ras) oncogene homolog | ALPS4, N-ras, NRAS1 |
| PIK3CA | phosphoinositide-3-kinase, catalytic, alpha polypeptide | MGC142161, MGC142163, PI3K, p110-alpha |
| PIK3CB | phosphoinositide-3-kinase, catalytic, beta polypeptide | DKFZp779K1237, MGC133043, PI3K, PI3KCB, PI3Kbeta, PIK3C1, p110-BETA |
| PIK3CD | phosphoinositide-3-kinase, catalytic, delta polypeptide | p110D |
| PIK3CG | phosphoinositide-3-kinase, catalytic, gamma polypeptide | PI3CG, PI3K, PI3Kgamma, PIK3 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | GRB1, p85, p85-ALPHA |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | P85B, p85, p85-BETA |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | DKFZp686P05226, FLJ41892, p55, p55-GAMMA |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 | F730038I15Rik, FOAP-2, P101-PI3K, p101 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | - |
| PPP3CA | protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform | CALN, CALNA, CALNA1, CCN1, CNA1, PPP2B |
| PPP3CB | protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform | CALNA2, CALNB |
| PPP3CC | protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform | CALNA3 |
| PPP3R1 | protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform | CALNB1, CNB, CNB1 |
| PPP3R2 | protein phosphatase 3 (formerly 2B), regulatory subunit B, beta isoform | PPP3RL |
| PRKCB | protein kinase C, beta | MGC41878, PKC-beta, PKCB, PRKCB1, PRKCB2 |
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | HCP, HCPH, HPTP1C, PTP-1C, SH-PTP1, SHP-1, SHP-1L, SHP1 |
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | MGC111543, MIG5, TC-25, p21-Rac1 |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | EN-7, Gx, HSPC022 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) | - |
| RASGRP3 | RAS guanyl releasing protein 3 (calcium and DAG-regulated) | GRP3, KIAA0846 |
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | MGC131774, NFKB3, p65 |
| SYK | spleen tyrosine kinase | DKFZp313N1010, FLJ25043, FLJ37489 |
| VAV1 | vav 1 guanine nucleotide exchange factor | VAV |
| VAV2 | vav 2 guanine nucleotide exchange factor | - |
| VAV3 | vav 3 guanine nucleotide exchange factor | FLJ40431 |
Chemokines
Chemokines, or chemotactic cytokines, are small proteins that can be secreted by immune cells and other cell types. They can be grouped in to the CC, CXC, XC, and CX3C families based on conserved cysteine residues. Chemokines recruit innate and adaptive immune cells to sites of inflammation throughout the body.
| Symbol | Name | Synonyms |
|---|---|---|
| C3 | complement component 3 | ARMD9, ASP, CPAMD1 |
| C5 | complement component 5 | CPAMD4, FLJ17816, FLJ17822, MGC142298 |
| C5AR1 | complement component 5a receptor 1 | C5A, C5AR, C5R1, CD88 |
| CAMP | cathelicidin antimicrobial peptide | CAP18, CRAMP, FALL-39, FALL39, HSD26, LL37 |
| CCBP2 | chemokine binding protein 2 | CCR10, CCR9, CMKBR9, D6, MGC126678, MGC138250, hD6 |
| CCL1 | chemokine (C-C motif) ligand 1 | I-309, P500, SCYA1, SISe, TCA3 |
| CCL11 | chemokine (C-C motif) ligand 11 | MGC22554, SCYA11 |
| CCL13 | chemokine (C-C motif) ligand 13 | CKb10, MCP-4, MGC17134, NCC-1, NCC1, SCYA13, SCYL1 |
| CCL14 | chemokine (C-C motif) ligand 14 | CC-1, CC-3, CKb1, FLJ16015, HCC-1, HCC-3, MCIF, NCC-2, NCC2, SCYA14, SCYL2, SY14 |
| CCL14-CCL15 | chemokine ligand 14, chemokine ligand 15 transcription unit | - |
| CCL15 | chemokine (C-C motif) ligand 15 | HCC-2, HMRP-2B, LKN1, Lkn-1, MIP-1d, MIP-5, NCC-3, NCC3, SCYA15, SCYL3, SY15 |
| CCL16 | chemokine (C-C motif) ligand 16 | CKb12, HCC-4, ILINCK, LCC-1, LEC, LMC, MGC117051, Mtn-1, NCC-4, NCC4, SCYA16, SCYL4 |
| CCL17 | chemokine (C-C motif) ligand 17 | A-152E5.3, ABCD-2, MGC138271, MGC138273, SCYA17, TARC |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | AMAC-1, AMAC1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18 |
| CCL19 | chemokine (C-C motif) ligand 19 | CKb11, ELC, MGC34433, MIP-3b, MIP3B, SCYA19 |
| CCL2 | chemokine (C-C motif) ligand 2 | GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF |
| CCL20 | chemokine (C-C motif) ligand 20 | CKb4, LARC, MIP-3a, MIP3A, SCYA20, ST38 |
| CCL21 | chemokine (C-C motif) ligand 21 | 6Ckine, CKb9, ECL, MGC34555, SCYA21, SLC, TCA4 |
| CCL22 | chemokine (C-C motif) ligand 22 | A-152E5.1, ABCD-1, DC/B-CK, MDC, MGC34554, SCYA22, STCP-1 |
| CCL23 | chemokine (C-C motif) ligand 23 | CK-BETA-8, CKb8, Ckb-8, Ckb-8-1, MIP-3, MIP3, MPIF-1, SCYA23 |
| CCL24 | chemokine (C-C motif) ligand 24 | Ckb-6, MPIF-2, MPIF2, SCYA24 |
| CCL25 | chemokine (C-C motif) ligand 25 | Ckb15, MGC150327, SCYA25, TECK |
| CCL26 | chemokine (C-C motif) ligand 26 | IMAC, MGC126714, MIP-4a, MIP-4alpha, SCYA26, TSC-1 |
| CCL27 | chemokine (C-C motif) ligand 27 | ALP, CTACK, CTAK, ESKINE, ILC, PESKY, SCYA27 |
| CCL28 | chemokine (C-C motif) ligand 28 | CCK1, MEC, MGC71902, SCYA28 |
| CCL3 | chemokine (C-C motif) ligand 3 | G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3 |
| CCL3L1 | chemokine (C-C motif) ligand 3-like 1 | 464.2, D17S1718, G0S19-2, LD78, LD78BETA, MGC104178, MGC12815, MGC182017, MIP1AP, SCYA3L, SCYA3L1 |
| CCL3L2 | chemokine (C-C motif) ligand 3-like 2 | G0S19-3, LD78gamma, SCYA3L2 |
| CCL3L3 | chemokine (C-C motif) ligand 3-like 3 | 464.2, D17S1718, LD78, LD78BETA, MGC12815, SCYA3L, SCYA3L1 |
| CCL4 | chemokine (C-C motif) ligand 4 | ACT2, AT744.1, G-26, LAG1, MGC104418, MGC126025, MGC126026, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4 |
| CCL4L1 | chemokine (C-C motif) ligand 4-like 1 | AT744.2, CCL4L, LAG-1, LAG1, SCYA4L |
| CCL4L2 | chemokine (C-C motif) ligand 4-like 2 | AT744.2, CCL4L, SCYA4L |
| CCL5 | chemokine (C-C motif) ligand 5 | D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228 |
| CCL7 | chemokine (C-C motif) ligand 7 | FIC, MARC, MCP-3, MCP3, MGC138463, MGC138465, NC28, SCYA6, SCYA7 |
| CCL8 | chemokine (C-C motif) ligand 8 | HC14, MCP-2, MCP2, SCYA10, SCYA8 |
| CCR1 | chemokine (C-C motif) receptor 1 | CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1 |
| CCR10 | chemokine (C-C motif) receptor 10 | GPR2 |
| CCR3 | chemokine (C-C motif) receptor 3 | CC-CKR-3, CD193, CKR3, CMKBR3, MGC102841 |
| CCR4 | chemokine (C-C motif) receptor 4 | CC-CKR-4, CD194, CKR4, CMKBR4, ChemR13, HGCN:14099, K5-5, MGC88293 |
| CCR5 | chemokine (C-C motif) receptor 5 | CC-CKR-5, CCCKR5, CD195, CKR-5, CKR5, CMKBR5, FLJ78003, IDDM22 |
| CCR6 | chemokine (C-C motif) receptor 6 | BN-1, CD196, CKR-L3, CKR6, CKRL3, CMKBR6, DCR2, DRY-6, GPR-CY4, GPR29, GPRCY4, STRL22 |
| CCR7 | chemokine (C-C motif) receptor 7 | BLR2, CD197, CDw197, CMKBR7, EBI1 |
| CCR8 | chemokine (C-C motif) receptor 8 | CDw198, CKR-L1, CKRL1, CMKBR8, CMKBRL2, CY6, GPR-CY6, MGC129966, MGC129973, TER1 |
| CCR9 | chemokine (C-C motif) receptor 9 | CDw199, GPR-9-6, GPR28 |
| CCRL1 | chemokine (C-C motif) receptor-like 1 | CC-CKR-11, CCBP2, CCR10, CCR11, CCX-CKR, CKR-11, PPR1, VSHK1 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 | CKRX, CRAM-A, CRAM-B, FLJ55815, HCR, MGC116710, MGC34104 |
| CKLF | chemokine-like factor | C32, CKLF1, CKLF2, CKLF3, CKLF4, HSPC224, UCK-1 |
| CMA1 | chymase 1, mast cell | CYH, MCT1, MGC119890, MGC119891, chymase |
| CMKLR1 | chemokine-like receptor 1 | CHEMERINR, ChemR23, DEZ, MGC126105, MGC126106 |
| CTSG | cathepsin G | CG, MGC23078 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | ABCD-3, C3Xkine, CXC3, CXC3C, NTN, NTT, SCYD1, fractalkine, neurotactin |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | CCRL1, CMKBRL1, CMKDR1, GPR13, GPRV28, V28 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | H174, I-TAC, IP-9, IP9, MGC102770, SCYB11, SCYB9B, b-R1 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | PBSF, SCYB12, SDF-1a, SDF-1b, SDF1, SDF1A, SDF1B, TLSF-a, TLSF-b, TPAR1 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | ANGIE, ANGIE2, BCA-1, BCA1, BLC, BLR1L, SCYB13 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | BMAC, BRAK, KS1, Kec, MGC10687, MIP-2g, NJAC, SCYB14, bolekine |
| CXCL16 | chemokine (C-X-C motif) ligand 16 | CXCLG16, SR-PSOX, SRPSOX |
| CXCL17 | chemokine (C-X-C motif) ligand 17 | DMC, Dcip1, MGC138300, UNQ473, VCC-1, VCC1 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, MIP2, MIP2A, SCYB2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | CINC-2b, GRO3, GROg, MIP-2b, MIP2B, SCYB3 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | ENA-78, SCYB5 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | CKA-3, GCP-2, GCP2, SCYB6 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | CMK, Humig, MIG, SCYB9, crg-10 |
| CXCR3 | chemokine (C-X-C motif) receptor 3 | CD182, CD183, CKR-L2, CMKAR3, GPR9, IP10-R, Mig-R, MigR |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM |
| CXCR5 | chemokine (C-X-C motif) receptor 5 | BLR1, CD185, MDR15, MGC117347 |
| CXCR6 | chemokine (C-X-C motif) receptor 6 | BONZO, CD186, STRL33, TYMSTR |
| CXCR7 | chemokine (C-X-C motif) receptor 7 | CMKOR1, GPR159, RDC1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 | CCN1, GIG1, IGFBP10 |
| CYSLTR1 | cysteinyl leukotriene receptor 1 | CYSLT1, CYSLT1R, CYSLTR, HG55, HMTMF81, MGC46139 |
| CYSLTR2 | cysteinyl leukotriene receptor 2 | CYSLT2, CYSLT2R, GPCR, HG57, HPN321, KPG_011, PSEC0146, hGPCR21 |
| DARC | Duffy blood group, chemokine receptor | CCBP1, CD234, Dfy, FY, GPD, GpFy, WBCQ1 |
| DEFA1 | defensin, alpha 1 | DEF1, DEFA2, HNP-1, HP-1, MGC138393, MRS |
| DEFA3 | defensin, alpha 3, neutrophil-specific | DEF3, HNP-3, HNP3, HP-3 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | DEF5, HD-5, MGC129728 |
| DEFB1 | defensin, beta 1 | BD1, DEFB-1, DEFB101, HBD1, MGC51822 |
| DEFB103A | defensin, beta 103A | DEFB103, DEFB3, HBD-3, HBD3, HBP-3, HBP3 |
| DEFB104A | defensin, beta 104A | BD-4, DEFB-4, DEFB104, DEFB4, MGC118942, MGC118944, MGC118945, hBD-4 |
| DEFB4 | defensin, beta 4 | DEFB-2, DEFB102, DEFB2, HBD-2, SAP1 |
| EDN1 | endothelin 1 | ET1, HDLCQ7 |
| EDN2 | endothelin 2 | ET2, PPET2 |
| EDN3 | endothelin 3 | ET3, MGC15067, MGC61498 |
| EDNRA | endothelin receptor type A | ETA, ETRA |
| EDNRB | endothelin receptor type B | ABCDS, ETB, ETBR, ETRB, HSCR, HSCR2 |
| FGF10 | fibroblast growth factor 10 | - |
| FGF2 | fibroblast growth factor 2 (basic) | BFGF, FGFB, HBGF-2 |
| FPR1 | formyl peptide receptor 1 | FMLP, FPR |
| FPR2 | formyl peptide receptor 2 | ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, HM63, LXA4R |
| FPR2 | formyl peptide receptor 2 | ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, HM63, LXA4R |
| GPR17 | G protein-coupled receptor 17 | DKFZp686M18273 |
| GPR32 | G protein-coupled receptor 32 | - |
| GPR33 | G protein-coupled receptor 33 (gene/pseudogene) | - |
| GPR44 | G protein-coupled receptor 44 | CD294, CRTH2, DP2 |
| GPR77 | G protein-coupled receptor 77 | C5L2, GPF77 |
| HTN3 | histatin 3 | HIS2, HTN2, HTN5 |
| IL8 | interleukin 8 | CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 |
| IL8RA | interleukin 8 receptor, alpha | C-C, C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, CXCR1, IL8R1, IL8RBA |
| IL8RB | interleukin 8 receptor, beta | CD182, CDw128b, CMKAR2, CXCR2, IL8R2, IL8RA |
| LECT2 | leukocyte cell-derived chemotaxin 2 | MGC126628, chm-II, chm2 |
| LTB4R | leukotriene B4 receptor | BLT1, BLTR, CMKRL1, GPR16, LTB4R1, LTBR1, P2RY7, P2Y7 |
| LTB4R2 | leukotriene B4 receptor 2 | BLT2, BLTR2, JULF2, KPG_004, NOP9 |
| PF4 | platelet factor 4 | CXCL4, MGC138298, SCYB4 |
| PF4V1 | platelet factor 4 variant 1 | CXCL4L1, CXCL4V1, PF4-ALT, PF4A, SCYB4V1 |
| PLAU | plasminogen activator, urokinase | ATF, UPA, URK, u-PA |
| PLAUR | plasminogen activator, urokinase receptor | CD87, UPAR, URKR |
| PLXNA1 | plexin A1 | NOV, NOVP, PLEXIN-A1, PLXN1 |
| PLXNA2 | plexin A2 | FLJ11751, FLJ30634, KIAA0463, OCT, PLXN2 |
| PLXNA3 | plexin A3 | 6.3, HSSEXGENE, PLEXIN-A3, PLXN3, PLXN4, SEX, XAP-6 |
| PLXNA4 | plexin A4 | DKFZp434G0625, DKFZp566O0546, FAYV2820, FLJ35026, FLJ38287, KIAA1550, PLEXA4, PLXNA4A, PLXNA4B, PRO34003 |
| PLXNB1 | plexin B1 | KIAA0407, MGC149167, PLEXIN-B1, PLXN5, SEP |
| PLXNB2 | plexin B2 | KIAA0315, MM1, Nbla00445, PLEXB2, dJ402G11.3 |
| PLXNB3 | plexin B3 | FLJ76953, PLEXB3, PLEXR, PLXN6 |
| PLXNC1 | plexin C1 | CD232, PLXN-C1, VESPR |
| PLXND1 | plexin D1 | KIAA0620, MGC75353, PLEXD1 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | B-TG1, Beta-TG, CTAP-III, CTAP3, CTAPIII, CXCL7, LA-PF4, LDGF, MDGF, NAP-2, PBP, SCYB7, TC1, TC2, TGB, TGB1, THBGB, THBGB1 |
| PPBPL1 | pro-platelet basic protein-like 1 | TGB2 |
| PROK2 | prokineticin 2 | BV8, KAL4, MIT1, PK2 |
| PTAFR | platelet-activating factor receptor | PAFR |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | EDN, RNS2 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | DUTT1, FLJ21882, MGC131599, MGC133277, SAX3 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | KIAA1568, SAX3 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) | FLJ21044, HGPPS, HGPS, RBIG1, RIG1 |
| RXFP3 | relaxin/insulin-like family peptide receptor 3 | GPCR135, MGC141998, MGC142000, RLN3R1, RXFPR3, SALPR |
| SAA1 | serum amyloid A1 | MGC111216, PIG4, SAA, TP53I4 |
| SAA2 | serum amyloid A2 | - |
| SBDS | Shwachman-Bodian-Diamond syndrome | CGI-97, FLJ10917, SDS, SWDS |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | Hsema-I, Hsema-III, MGC133243, SEMA1, SEMAD, SEMAIII, SEMAL, SemD, coll-1 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | FLJ34863, LUCA-1, SEMA5, SEMAA, SemA, semaV |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | SEMAE, SemE |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | MGC39708, Sema-Z2, coll-2 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | KIAA0331, M-SEMAH, M-SemaK, SEMAH, coll-5 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F | SEMA-IV, SEMA4, SEMAK |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G | FLJ00014, MGC119473, sem2 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | CORD10, FLJ12287, RP35, SEMAB, SEMB |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | KIAA1745, MGC131831, SEMAC, SemC |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | FLJ20369, KIAA1739, M-SEMA-F, MGC126382, MGC126383, SEMACL1, SEMAF, SEMAI |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | C9orf164, CD100, FLJ33485, FLJ34282, FLJ39737, FLJ46484, M-sema-G, MGC169138, MGC169141, SEMAJ, coll-4 |
| SEMA4F | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F | M-SEMA, PRO2353, SEMAM, SEMAW, m-Sema-M |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G | FLJ20590, KIAA1619, MGC102867 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | FLJ12815, SEMAF, semF |
| SEMA5B | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B | FLJ10372, KIAA1445, SEMAG, SemG |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | HT018, KIAA1368, SEMA, SEMA6A1, SEMAQ, VIA |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B | SEM-SEMA-Y, SEMA-VIB, SEMAN, semaZ |
| SEMA6C | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C | SEMAY, m-SemaY, m-SemaY2 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D | FLJ11598, KIAA1479 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) | CD108, CDw108, H-SEMA-K1, H-Sema-L, JMH, MGC126692, MGC126696, SEMAK1, SEMAL |
| SLIT1 | slit homolog 1 (Drosophila) | MEGF4, MGC164811, SLIL1, SLIT3, Slit-1 |
| SLIT2 | slit homolog 2 (Drosophila) | FLJ14420, SLIL3, Slit-2 |
| TNC | tenascin C | HXB, MGC167029, TN |
| TYMP | thymidine phosphorylase | ECGF1, MNGIE, PDECGF, TP, hPD-ECGF |
| XCL1 | chemokine (C motif) ligand 1 | ATAC, LPTN, LTN, SCM-1, SCM-1a, SCM1, SCYC1 |
| XCL2 | chemokine (C motif) ligand 2 | SCM-1b, SCM1B, SCYC2 |
| XCR1 | chemokine (C motif) receptor 1 | CCXCR1, GPR5 |
Cytokines
Cytokines are molecules that enable cells of the immune system to communicate with each other across long distances. During infection and inflammation, the different cytokines that are released tailor the immune response to a specific trigger.
| Symbol | Name | Synonyms |
|---|---|---|
| ACVR1B | activin A receptor, type IB | ACTRIB, ACVRLK4, ALK4, SKR2 |
| ACVR1C | activin A receptor, type IC | ACVRLK7, ALK7 |
| ACVR2A | activin A receptor, type IIA | ACTRII, ACVR2 |
| ACVR2B | activin A receptor, type IIB | ACTRIIB, ActR-IIB, MGC116908 |
| ACVRL1 | activin A receptor type II-like 1 | ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I |
| ADCYAP1R1 | adenylate cyclase activating polypeptide 1 (pituitary) receptor type I | PAC1, PACAPR, PACAPRI |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | ACDC, ACRP30, ADIPQTL1, ADPN, APM-1, APM1, GBP28, adiponectin |
| ADIPOR1 | adiponectin receptor 1 | ACDCR1, CGI-45, CGI45, FLJ25385, FLJ42464, PAQR1, TESBP1A |
| ADIPOR2 | adiponectin receptor 2 | ACDCR2, FLJ21432, MGC4640, PAQR2 |
| ADM | adrenomedullin | AM |
| ADM2 | adrenomedullin 2 | AM2, FLJ21135, dJ579N16.4 |
| ADRB1 | adrenergic, beta-1-, receptor | ADRB1R, B1AR, BETA1AR, RHR |
| ADRB2 | adrenergic, beta-2-, receptor, surface | ADRB2R, ADRBR, B2AR, BAR, BETA2AR |
| AGRP | agouti related protein homolog (mouse) | AGRT, ART, ASIP2, MGC118963 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | ANHU, FLJ92595, FLJ97926, SERPINA8 |
| AGTR1 | angiotensin II receptor, type 1 | AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT1R, AT2R1, AT2R1A, AT2R1B, HAT1R |
| AGTR2 | angiotensin II receptor, type 2 | AT2, ATGR2, MRX88 |
| AMBN | ameloblastin (enamel matrix protein) | - |
| AMELX | amelogenin (amelogenesis imperfecta 1, X-linked) | AIH1, ALGN, AMG, AMGL, AMGX |
| AMH | anti-Mullerian hormone | MIF, MIS |
| AMHR2 | anti-Mullerian hormone receptor, type II | AMHR, MISR2, MISRII |
| ANGPT1 | angiopoietin 1 | AGP1, AGPT, ANG1 |
| ANGPT4 | angiopoietin 4 | AGP4, ANG-3, ANG4, MGC138181, MGC138183 |
| ANGPTL1 | angiopoietin-like 1 | ANG3, ANGPT3, ARP1, AngY, KIAA0351, UNQ162, dJ595C2.2 |
| ANGPTL2 | angiopoietin-like 2 | ARP2, HARP, MGC8889 |
| ANGPTL3 | angiopoietin-like 3 | ANGPT5 |
| ANGPTL4 | angiopoietin-like 4 | ANGPTL2, ARP4, FIAF, HFARP, NL2, PGAR, pp1158 |
| ANGPTL5 | angiopoietin-like 5 | - |
| ANGPTL6 | angiopoietin-like 6 | AGF, ARP5 |
| ANGPTL7 | angiopoietin-like 7 | AngX, CDT6, RP4-647M16.2, dJ647M16.1 |
| APLN | apelin | XNPEP2 |
| APLNR | apelin receptor | AGTRL1, APJ, APJR, FLJ90771, MGC45246 |
| AR | androgen receptor | AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM |
| AREG | amphiregulin | AR, CRDGF, MGC13647, SDGF |
| ARMET | arginine-rich, mutated in early stage tumors | ARP, MANF, MGC142148, MGC142150 |
| ARMETL1 | arginine-rich, mutated in early stage tumors-like 1 | cdnf |
| ARTN | artemin | ENOVIN, EVN, NBN |
| AVP | arginine vasopressin | ADH, ARVP, AVP-NPII, AVRP, VP |
| AVPR1A | arginine vasopressin receptor 1A | AVPR1 |
| AVPR1B | arginine vasopressin receptor 1B | AVPR3 |
| AVPR2 | arginine vasopressin receptor 2 | ADHR, DI1, DIR, DIR3, MGC126533, MGC138386, NDI, V2R |
| AZU1 | azurocidin 1 | AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC |
| BDNF | brain-derived neurotrophic factor | MGC34632 |
| BMP1 | bone morphogenetic protein 1 | FLJ44432, PCOLC, PCP, TLD, pCP-2 |
| BMP10 | bone morphogenetic protein 10 | MGC126783 |
| BMP15 | bone morphogenetic protein 15 | GDF9B, ODG2, POF4 |
| BMP2 | bone morphogenetic protein 2 | BMP2A |
| BMP3 | bone morphogenetic protein 3 | BMP-3A |
| BMP4 | bone morphogenetic protein 4 | BMP2B, BMP2B1, MCOPS6, OFC11, ZYME |
| BMP5 | bone morphogenetic protein 5 | MGC34244 |
| BMP6 | bone morphogenetic protein 6 | VGR, VGR1 |
| BMP7 | bone morphogenetic protein 7 | OP-1 |
| BMP8A | bone morphogenetic protein 8a | FLJ14351, FLJ45264 |
| BMP8B | bone morphogenetic protein 8b | BMP8, MGC131757, OP2 |
| BMPR1A | bone morphogenetic protein receptor, type IA | 10q23del, ACVRLK3, ALK3, CD292, SKR5 |
| BMPR1B | bone morphogenetic protein receptor, type IB | ALK-6, ALK6, CDw293 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | BMPR-II, BMPR3, BMR2, BRK-3, FLJ41585, FLJ76945, PPH1, T-ALK |
| BRD8 | bromodomain containing 8 | SMAP, SMAP2, p120 |
| BTC | betacellulin | - |
| C19orf10 | chromosome 19 open reading frame 10 | EUROIMAGE1875335, IL25, IL27, IL27w, R33729_1, SF20 |
| C3 | complement component 3 | ARMD9, ASP, CPAMD1 |
| C3AR1 | complement component 3a receptor 1 | AZ3B, C3AR, HNFAG09 |
| C5 | complement component 5 | CPAMD4, FLJ17816, FLJ17822, MGC142298 |
| C5AR1 | complement component 5a receptor 1 | C5A, C5AR, C5R1, CD88 |
| CALCA | calcitonin-related polypeptide alpha | CALC1, CGRP, CGRP-I, CGRP1, CT, KC, MGC126648 |
| CALCB | calcitonin-related polypeptide beta | CALC2, CGRP-II, CGRP2, FLJ30166 |
| CALCR | calcitonin receptor | CRT, CTR, CTR1 |
| CALCRL | calcitonin receptor-like | CGRPR, CRLR |
| CAMP | cathelicidin antimicrobial peptide | CAP18, CRAMP, FALL-39, FALL39, HSD26, LL37 |
| CAT | catalase | MGC138422, MGC138424 |
| CCBP2 | chemokine binding protein 2 | CCR10, CCR9, CMKBR9, D6, MGC126678, MGC138250, hD6 |
| CCK | cholecystokinin | MGC117187 |
| CCL1 | chemokine (C-C motif) ligand 1 | I-309, P500, SCYA1, SISe, TCA3 |
| CCL11 | chemokine (C-C motif) ligand 11 | MGC22554, SCYA11 |
| CCL13 | chemokine (C-C motif) ligand 13 | CKb10, MCP-4, MGC17134, NCC-1, NCC1, SCYA13, SCYL1 |
| CCL14 | chemokine (C-C motif) ligand 14 | CC-1, CC-3, CKb1, FLJ16015, HCC-1, HCC-3, MCIF, NCC-2, NCC2, SCYA14, SCYL2, SY14 |
| CCL14-CCL15 | chemokine ligand 14, chemokine ligand 15 transcription unit | - |
| CCL15 | chemokine (C-C motif) ligand 15 | HCC-2, HMRP-2B, LKN1, Lkn-1, MIP-1d, MIP-5, NCC-3, NCC3, SCYA15, SCYL3, SY15 |
| CCL16 | chemokine (C-C motif) ligand 16 | CKb12, HCC-4, ILINCK, LCC-1, LEC, LMC, MGC117051, Mtn-1, NCC-4, NCC4, SCYA16, SCYL4 |
| CCL17 | chemokine (C-C motif) ligand 17 | A-152E5.3, ABCD-2, MGC138271, MGC138273, SCYA17, TARC |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | AMAC-1, AMAC1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18 |
| CCL19 | chemokine (C-C motif) ligand 19 | CKb11, ELC, MGC34433, MIP-3b, MIP3B, SCYA19 |
| CCL2 | chemokine (C-C motif) ligand 2 | GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF |
| CCL20 | chemokine (C-C motif) ligand 20 | CKb4, LARC, MIP-3a, MIP3A, SCYA20, ST38 |
| CCL21 | chemokine (C-C motif) ligand 21 | 6Ckine, CKb9, ECL, MGC34555, SCYA21, SLC, TCA4 |
| CCL22 | chemokine (C-C motif) ligand 22 | A-152E5.1, ABCD-1, DC/B-CK, MDC, MGC34554, SCYA22, STCP-1 |
| CCL23 | chemokine (C-C motif) ligand 23 | CK-BETA-8, CKb8, Ckb-8, Ckb-8-1, MIP-3, MIP3, MPIF-1, SCYA23 |
| CCL24 | chemokine (C-C motif) ligand 24 | Ckb-6, MPIF-2, MPIF2, SCYA24 |
| CCL25 | chemokine (C-C motif) ligand 25 | Ckb15, MGC150327, SCYA25, TECK |
| CCL26 | chemokine (C-C motif) ligand 26 | IMAC, MGC126714, MIP-4a, MIP-4alpha, SCYA26, TSC-1 |
| CCL27 | chemokine (C-C motif) ligand 27 | ALP, CTACK, CTAK, ESKINE, ILC, PESKY, SCYA27 |
| CCL28 | chemokine (C-C motif) ligand 28 | CCK1, MEC, MGC71902, SCYA28 |
| CCL3 | chemokine (C-C motif) ligand 3 | G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3 |
| CCL3L1 | chemokine (C-C motif) ligand 3-like 1 | 464.2, D17S1718, G0S19-2, LD78, LD78BETA, MGC104178, MGC12815, MGC182017, MIP1AP, SCYA3L, SCYA3L1 |
| CCL3L2 | chemokine (C-C motif) ligand 3-like 2 | G0S19-3, LD78gamma, SCYA3L2 |
| CCL3L3 | chemokine (C-C motif) ligand 3-like 3 | 464.2, D17S1718, LD78, LD78BETA, MGC12815, SCYA3L, SCYA3L1 |
| CCL4 | chemokine (C-C motif) ligand 4 | ACT2, AT744.1, G-26, LAG1, MGC104418, MGC126025, MGC126026, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4 |
| CCL4L1 | chemokine (C-C motif) ligand 4-like 1 | AT744.2, CCL4L, LAG-1, LAG1, SCYA4L |
| CCL4L2 | chemokine (C-C motif) ligand 4-like 2 | AT744.2, CCL4L, SCYA4L |
| CCL5 | chemokine (C-C motif) ligand 5 | D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228 |
| CCL7 | chemokine (C-C motif) ligand 7 | FIC, MARC, MCP-3, MCP3, MGC138463, MGC138465, NC28, SCYA6, SCYA7 |
| CCL8 | chemokine (C-C motif) ligand 8 | HC14, MCP-2, MCP2, SCYA10, SCYA8 |
| CCR1 | chemokine (C-C motif) receptor 1 | CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1 |
| CCR10 | chemokine (C-C motif) receptor 10 | GPR2 |
| CCR3 | chemokine (C-C motif) receptor 3 | CC-CKR-3, CD193, CKR3, CMKBR3, MGC102841 |
| CCR4 | chemokine (C-C motif) receptor 4 | CC-CKR-4, CD194, CKR4, CMKBR4, ChemR13, HGCN:14099, K5-5, MGC88293 |
| CCR5 | chemokine (C-C motif) receptor 5 | CC-CKR-5, CCCKR5, CD195, CKR-5, CKR5, CMKBR5, FLJ78003, IDDM22 |
| CCR6 | chemokine (C-C motif) receptor 6 | BN-1, CD196, CKR-L3, CKR6, CKRL3, CMKBR6, DCR2, DRY-6, GPR-CY4, GPR29, GPRCY4, STRL22 |
| CCR7 | chemokine (C-C motif) receptor 7 | BLR2, CD197, CDw197, CMKBR7, EBI1 |
| CCR8 | chemokine (C-C motif) receptor 8 | CDw198, CKR-L1, CKRL1, CMKBR8, CMKBRL2, CY6, GPR-CY6, MGC129966, MGC129973, TER1 |
| CCR9 | chemokine (C-C motif) receptor 9 | CDw199, GPR-9-6, GPR28 |
| CCRL1 | chemokine (C-C motif) receptor-like 1 | CC-CKR-11, CCBP2, CCR10, CCR11, CCX-CKR, CKR-11, PPR1, VSHK1 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 | CKRX, CRAM-A, CRAM-B, FLJ55815, HCR, MGC116710, MGC34104 |
| CD320 | CD320 molecule | 8D6, 8D6A |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | Bp50, CDW40, MGC9013, TNFRSF5, p50 |
| CD40LG | CD40 ligand | CD154, CD40L, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, gp39, hCD40L |
| CD70 | CD70 molecule | CD27L, CD27LG, TNFSF7 |
| CECR1 | cat eye syndrome chromosome region, candidate 1 | ADGF, IDGFL |
| CER1 | cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis) | DAND4, MGC119894, MGC119895, MGC96951 |
| CGA | glycoprotein hormones, alpha polypeptide | CG-ALPHA, FSHA, GPHA1, GPHa, HCG, LHA, TSHA |
| CGB | chorionic gonadotropin, beta polypeptide | CGB3, hCGB |
| CGB1 | chorionic gonadotropin, beta polypeptide 1 | - |
| CGB2 | chorionic gonadotropin, beta polypeptide 2 | - |
| CGB5 | chorionic gonadotropin, beta polypeptide 5 | HCG, MGC119822 |
| CGB7 | chorionic gonadotropin, beta polypeptide 7 | CG-beta-a, FLJ35403, FLJ43118 |
| CGB8 | chorionic gonadotropin, beta polypeptide 8 | - |
| CHGA | chromogranin A (parathyroid secretory protein 1) | CGA |
| CHGB | chromogranin B (secretogranin 1) | SCG1 |
| CKLF | chemokine-like factor | C32, CKLF1, CKLF2, CKLF3, CKLF4, HSPC224, UCK-1 |
| CLCF1 | cardiotrophin-like cytokine factor 1 | BSF3, CISS2, CLC, NNT1, NR6 |
| CLEC11A | C-type lectin domain family 11, member A | CLECSF3, LSLCL, P47, SCGF |
| CMA1 | chymase 1, mast cell | CYH, MCT1, MGC119890, MGC119891, chymase |
| CMKLR1 | chemokine-like receptor 1 | CHEMERINR, ChemR23, DEZ, MGC126105, MGC126106 |
| CMTM1 | CKLF-like MARVEL transmembrane domain containing 1 | CKLFH, CKLFH1, CKLFSF1, MGC71870 |
| CMTM2 | CKLF-like MARVEL transmembrane domain containing 2 | CKLFSF2, MGC39436 |
| CMTM3 | CKLF-like MARVEL transmembrane domain containing 3 | BNAS2, CKLFSF3, FLJ31762, MGC51956 |
| CMTM4 | CKLF-like MARVEL transmembrane domain containing 4 | CKLFSF4 |
| CMTM5 | CKLF-like MARVEL transmembrane domain containing 5 | CKLFSF5, FLJ37521 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | CKLFSF6, FLJ20396, PRO2219 |
| CMTM7 | CKLF-like MARVEL transmembrane domain containing 7 | CKLFSF7, FLJ30992 |
| CMTM8 | CKLF-like MARVEL transmembrane domain containing 8 | CKLFSF8, CKLFSF8-V2 |
| CNTF | ciliary neurotrophic factor | HCNTF |
| CNTFR | ciliary neurotrophic factor receptor | MGC1774 |
| CORT | cortistatin | CST-14, CST-17, CST-29 |
| CRH | corticotropin releasing hormone | CRF |
| CRHR1 | corticotropin releasing hormone receptor 1 | CRF-R, CRF1, CRFR1, CRH-R1h, CRHR, CRHR1f |
| CRHR2 | corticotropin releasing hormone receptor 2 | CRFR2 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | MGC138194, S52 |
| CRLF1 | cytokine receptor-like factor 1 | CISS, CISS1, CLF, CLF-1, NR6 |
| CRLF2 | cytokine receptor-like factor 2 | CRL2, CRLF2Y, TSLPR |
| CRLF3 | cytokine receptor-like factor 3 | CREME9, CYTOR4, FRWS, MGC20661 |
| CSF1 | colony stimulating factor 1 (macrophage) | MCSF, MGC31930 |
| CSF1R | colony stimulating factor 1 receptor | C-FMS, CD115, CSFR, FIM2, FMS |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) | GMCSF, MGC131935, MGC138897 |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) | CD116, CDw116, CSF2R, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, GM-CSF-R-alpha, GMCSFR, GMR, MGC3848, MGC4838 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | CD131, CDw131, IL3RB, IL5RB |
| CSF3 | colony stimulating factor 3 (granulocyte) | G-CSF, GCSF, MGC45931 |
| CSF3R | colony stimulating factor 3 receptor (granulocyte) | CD114, GCSFR |
| CSH1 | chorionic somatomammotropin hormone 1 (placental lactogen) | CSA, CSMT, FLJ75407, PL |
| CSH2 | chorionic somatomammotropin hormone 2 | CS-2, CSB, hCS-B |
| CSHL1 | chorionic somatomammotropin hormone-like 1 | CS-5, CSHP1, CSL, MGC149868, hCS-L |
| CSPG5 | chondroitin sulfate proteoglycan 5 (neuroglycan C) | MGC44034, NGC |
| CTF1 | cardiotrophin 1 | CT-1, CT1 |
| CTGF | connective tissue growth factor | CCN2, HCS24, IGFBP8, MGC102839, NOV2 |
| CTSG | cathepsin G | CG, MGC23078 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | ABCD-3, C3Xkine, CXC3, CXC3C, NTN, NTT, SCYD1, fractalkine, neurotactin |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | CCRL1, CMKBRL1, CMKDR1, GPR13, GPRV28, V28 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | H174, I-TAC, IP-9, IP9, MGC102770, SCYB11, SCYB9B, b-R1 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | PBSF, SCYB12, SDF-1a, SDF-1b, SDF1, SDF1A, SDF1B, TLSF-a, TLSF-b, TPAR1 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | ANGIE, ANGIE2, BCA-1, BCA1, BLC, BLR1L, SCYB13 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | BMAC, BRAK, KS1, Kec, MGC10687, MIP-2g, NJAC, SCYB14, bolekine |
| CXCL16 | chemokine (C-X-C motif) ligand 16 | CXCLG16, SR-PSOX, SRPSOX |
| CXCL17 | chemokine (C-X-C motif) ligand 17 | DMC, Dcip1, MGC138300, UNQ473, VCC-1, VCC1 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, MIP2, MIP2A, SCYB2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | CINC-2b, GRO3, GROg, MIP-2b, MIP2B, SCYB3 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | ENA-78, SCYB5 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | CKA-3, GCP-2, GCP2, SCYB6 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | CMK, Humig, MIG, SCYB9, crg-10 |
| CXCR3 | chemokine (C-X-C motif) receptor 3 | CD182, CD183, CKR-L2, CMKAR3, GPR9, IP10-R, Mig-R, MigR |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM |
| CXCR5 | chemokine (C-X-C motif) receptor 5 | BLR1, CD185, MDR15, MGC117347 |
| CXCR6 | chemokine (C-X-C motif) receptor 6 | BONZO, CD186, STRL33, TYMSTR |
| CXCR7 | chemokine (C-X-C motif) receptor 7 | CMKOR1, GPR159, RDC1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 | CCN1, GIG1, IGFBP10 |
| CYSLTR1 | cysteinyl leukotriene receptor 1 | CYSLT1, CYSLT1R, CYSLTR, HG55, HMTMF81, MGC46139 |
| CYSLTR2 | cysteinyl leukotriene receptor 2 | CYSLT2, CYSLT2R, GPCR, HG57, HPN321, KPG_011, PSEC0146, hGPCR21 |
| DARC | Duffy blood group, chemokine receptor | CCBP1, CD234, Dfy, FY, GPD, GpFy, WBCQ1 |
| DEFA1 | defensin, alpha 1 | DEF1, DEFA2, HNP-1, HP-1, MGC138393, MRS |
| DEFA3 | defensin, alpha 3, neutrophil-specific | DEF3, HNP-3, HNP3, HP-3 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | DEF5, HD-5, MGC129728 |
| DEFB1 | defensin, beta 1 | BD1, DEFB-1, DEFB101, HBD1, MGC51822 |
| DEFB103A | defensin, beta 103A | DEFB103, DEFB3, HBD-3, HBD3, HBP-3, HBP3 |
| DEFB104A | defensin, beta 104A | BD-4, DEFB-4, DEFB104, DEFB4, MGC118942, MGC118944, MGC118945, hBD-4 |
| DEFB4 | defensin, beta 4 | DEFB-2, DEFB102, DEFB2, HBD-2, SAP1 |
| DKK1 | dickkopf homolog 1 (Xenopus laevis) | DKK-1, SK |
| EBI3 | Epstein-Barr virus induced 3 | IL27B |
| EDN1 | endothelin 1 | ET1, HDLCQ7 |
| EDN2 | endothelin 2 | ET2, PPET2 |
| EDN3 | endothelin 3 | ET3, MGC15067, MGC61498 |
| EDNRA | endothelin receptor type A | ETA, ETRA |
| EDNRB | endothelin receptor type B | ABCDS, ETB, ETBR, ETRB, HSCR, HSCR2 |
| EGF | epidermal growth factor (beta-urogastrone) | HOMG4, URG |
| EGFR | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | ERBB, ERBB1, HER1, PIG61, mENA |
| ENG | endoglin | CD105, END, FLJ41744, HHT1, ORW, ORW1 |
| EPGN | epithelial mitogen homolog (mouse) | ALGV3072, EPG, FLJ75542, PRO9904, epigen |
| EPO | erythropoietin | EP, MGC138142, MVCD2 |
| EPOR | erythropoietin receptor | MGC138358 |
| EREG | epiregulin | ER |
| ESM1 | endothelial cell-specific molecule 1 | endocan |
| ESR1 | estrogen receptor 1 | DKFZp686N23123, ER, ESR, ESRA, Era, NR3A1 |
| ESR2 | estrogen receptor 2 (ER beta) | ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 |
| ESRRA | estrogen-related receptor alpha | ERR1, ERRa, ERRalpha, ESRL1, NR3B1 |
| ESRRB | estrogen-related receptor beta | DFNB35, ERR2, ERRb, ERRbeta, ERRbeta-2, ESRL2, NR3B2 |
| ESRRG | estrogen-related receptor gamma | DKFZp781L1617, ERR3, FLJ16023, KIAA0832, NR3B3 |
| FAM3B | family with sequence similarity 3, member B | 2-21, C21orf11, C21orf76, ORF9, PANDER, PRED44 |
| FAM3C | family with sequence similarity 3, member C | GS3786, ILEI |
| FAM3D | family with sequence similarity 3, member D | EF7, OIT1 |
| FASLG | Fas ligand (TNF superfamily, member 6) | APT1LG1, CD178, CD95L, FASL, TNFSF6 |
| FGF1 | fibroblast growth factor 1 (acidic) | AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-alpha, FGFA, GLIO703, HBGF1 |
| FGF10 | fibroblast growth factor 10 | - |
| FGF11 | fibroblast growth factor 11 | FHF3, FLJ16061, MGC102953, MGC45269 |
| FGF12 | fibroblast growth factor 12 | FGF12B, FHF1 |
| FGF13 | fibroblast growth factor 13 | FGF2, FHF-2, FHF2 |
| FGF14 | fibroblast growth factor 14 | FHF4, MGC119129, SCA27 |
| FGF16 | fibroblast growth factor 16 | - |
| FGF17 | fibroblast growth factor 17 | FGF-13 |
| FGF18 | fibroblast growth factor 18 | FGF-18, ZFGF5 |
| FGF19 | fibroblast growth factor 19 | - |
| FGF2 | fibroblast growth factor 2 (basic) | BFGF, FGFB, HBGF-2 |
| FGF20 | fibroblast growth factor 20 | - |
| FGF21 | fibroblast growth factor 21 | - |
| FGF22 | fibroblast growth factor 22 | - |
| FGF23 | fibroblast growth factor 23 | ADHR, HPDR2, HYPF, PHPTC |
| FGF3 | fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog) | HBGF-3, INT2 |
| FGF4 | fibroblast growth factor 4 | HBGF-4, HST, HST-1, HSTF1, K-FGF, KFGF |
| FGF5 | fibroblast growth factor 5 | HBGF-5, Smag-82 |
| FGF6 | fibroblast growth factor 6 | HBGF-6, HST2 |
| FGF7 | fibroblast growth factor 7 (keratinocyte growth factor) | HBGF-7, KGF |
| FGF8 | fibroblast growth factor 8 (androgen-induced) | AIGF, HBGF-8, KAL6, MGC149376 |
| FGF9 | fibroblast growth factor 9 (glia-activating factor) | GAF, HBFG-9, MGC119914, MGC119915 |
| FGFR1 | fibroblast growth factor receptor 1 | BFGFR, CD331, CEK, FGFBR, FLG, FLJ99988, FLT2, HBGFR, KAL2, N-SAM, OGD |
| FGFR2 | fibroblast growth factor receptor 2 | BEK, BFR-1, CD332, CEK3, CFD1, ECT1, FLJ98662, JWS, K-SAM, KGFR, TK14, TK25 |
| FGFR3 | fibroblast growth factor receptor 3 | ACH, CD333, CEK2, HSFGFR3EX, JTK4 |
| FGFR4 | fibroblast growth factor receptor 4 | CD334, JTK2, MGC20292, TKF |
| FGFRL1 | fibroblast growth factor receptor-like 1 | FGFR5, FHFR |
| FIGF | c-fos induced growth factor (vascular endothelial growth factor D) | VEGF-D, VEGFD |
| FIGNL2 | fidgetin-like 2 | - |
| FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | FLT, VEGFR1 |
| FLT3 | fms-related tyrosine kinase 3 | CD135, FLK2, STK1 |
| FLT3LG | fms-related tyrosine kinase 3 ligand | FL |
| FLT4 | fms-related tyrosine kinase 4 | FLT41, LMPH1A, PCL, VEGFR3 |
| FPR1 | formyl peptide receptor 1 | FMLP, FPR |
| FPR2 | formyl peptide receptor 2 | ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, HM63, LXA4R |
| FPR2 | formyl peptide receptor 2 | ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, HM63, LXA4R |
| FSHB | follicle stimulating hormone, beta polypeptide | - |
| FSHR | follicle stimulating hormone receptor | FSHRO, LGR1, MGC141667, MGC141668, ODG1 |
| GAL | galanin prepropeptide | GALN, GLNN, GMAP, MGC40167 |
| GALP | galanin-like peptide | - |
| GALR2 | galanin receptor 2 | GALNR2, MGC125983, MGC125984 |
| GALR3 | galanin receptor 3 | - |
| GAST | gastrin | GAS |
| GCG | glucagon | GLP1, GLP2, GRPP |
| GCGR | glucagon receptor | GGR, MGC138246 |
| GDF1 | growth differentiation factor 1 | - |
| GDF10 | growth differentiation factor 10 | BMP-3b, BMP3B |
| GDF11 | growth differentiation factor 11 | BMP-11, BMP11 |
| GDF15 | growth differentiation factor 15 | GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB |
| GDF2 | growth differentiation factor 2 | BMP-9, BMP9 |
| GDF3 | growth differentiation factor 3 | - |
| GDF5 | growth differentiation factor 5 | BMP14, CDMP1, LAP4, OS5, SYNS2 |
| GDF6 | growth differentiation factor 6 | BMP13, CDMP2, KFS, KFSL, MGC158100, MGC158101, SGM1 |
| GDF7 | growth differentiation factor 7 | BMP12 |
| GDF9 | growth differentiation factor 9 | - |
| GDNF | glial cell derived neurotrophic factor | ATF1, ATF2, HFB1-GDNF |
| GH1 | growth hormone 1 | GH, GH-N, GHN, hGH-N |
| GH2 | growth hormone 2 | GH-V, GHL, GHV, hGH-V |
| GHR | growth hormone receptor | GHBP |
| GHRH | growth hormone releasing hormone | GHRF, GRF, MGC119781 |
| GHRHR | growth hormone releasing hormone receptor | GHRFR, GHRHRpsv, GRFR |
| GHRL | ghrelin/obestatin prepropeptide | MTLRP, obestatin |
| GHSR | growth hormone secretagogue receptor | - |
| GIP | gastric inhibitory polypeptide | - |
| GIPR | gastric inhibitory polypeptide receptor | MGC126722 |
| GKN1 | gastrokine 1 | AMP18, BRICD1, CA11, FOV, MGC70354, foveolin |
| GLP1R | glucagon-like peptide 1 receptor | MGC138331 |
| GLP2R | glucagon-like peptide 2 receptor | - |
| GMFB | glia maturation factor, beta | GMF |
| GMFG | glia maturation factor, gamma | GMF-GAMMA, MGC126867 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) | GNRH, GRH, LHRH, LNRH |
| GNRH2 | gonadotropin-releasing hormone 2 | GnRH-II, LH-RHII |
| GNRHR | gonadotropin-releasing hormone receptor | GNRHR1, GRHR, LHRHR, LRHR |
| GPER | G protein-coupled estrogen receptor 1 | CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPR30, LERGU, LERGU2, LyGPR, MGC99678 |
| GPHA2 | glycoprotein hormone alpha 2 | A2, GPA2, MGC126572, ZSIG51 |
| GPHB5 | glycoprotein hormone beta 5 | B5, GPB5, ZLUT1 |
| GPI | glucose phosphate isomerase | AMF, GNPI, NLK, PGI, PHI, SA-36 |
| GPR17 | G protein-coupled receptor 17 | DKFZp686M18273 |
| GPR32 | G protein-coupled receptor 32 | - |
| GPR33 | G protein-coupled receptor 33 (gene/pseudogene) | - |
| GPR44 | G protein-coupled receptor 44 | CD294, CRTH2, DP2 |
| GPR77 | G protein-coupled receptor 77 | C5L2, GPF77 |
| GREM1 | gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis) | CKTSF1B1, DAND2, DRM, GREMLIN, IHG-2, MGC126660, PIG2 |
| GREM2 | gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis) | CKTSF1B2, DAND3, PRDC |
| GRN | granulin | GEP, GP88, PCDGF, PEPI, PGRN |
| GRP | gastrin-releasing peptide | BN, GRP-10, preproGRP, proGRP |
| GUCA2A | guanylate cyclase activator 2A (guanylin) | GUANYLIN, GUCA2, STARA |
| HAMP | hepcidin antimicrobial peptide | HEPC, HEPCIDIN, HFE2B, LEAP-1, LEAP1, PLTR |
| HBEGF | heparin-binding EGF-like growth factor | DTR, DTS, DTSF, HEGFL |
| HDGF | hepatoma-derived growth factor (high-mobility group protein 1-like) | DKFZp686J1764, FLJ96580, HMG1L2 |
| HDGFRP3 | hepatoma-derived growth factor, related protein 3 | CGI-142, HDGF2 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | F-TCF, HGFB, HPTA, SF |
| HNF4A | hepatocyte nuclear factor 4, alpha | FLJ39654, HNF4, HNF4a7, HNF4a8, HNF4a9, HNF4alpha, MODY, MODY1, NR2A1, NR2A21, TCF, TCF14 |
| HNF4G | hepatocyte nuclear factor 4, gamma | NR2A2, NR2A3 |
| HTN3 | histatin 3 | HIS2, HTN2, HTN5 |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A | 5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3 |
| HTR3B | 5-hydroxytryptamine (serotonin) receptor 3B | 5-HT3B |
| HTR3C | 5-hydroxytryptamine (serotonin) receptor 3, family member C | - |
| HTR3D | 5-hydroxytryptamine (serotonin) receptor 3 family member D | MGC119636, MGC119637 |
| HTR3E | 5-hydroxytryptamine (serotonin) receptor 3, family member E | 5-HT3c1, MGC120035, MGC120036, MGC120037 |
| IAPP | islet amyloid polypeptide | AMYLIN, DAP, IAP |
| IFNA1 | interferon, alpha 1 | IFL, IFN, IFN-ALPHA, IFNA13, IFNA@, MGC138207, MGC138505, MGC138507 |
| IFNA10 | interferon, alpha 10 | MGC119878, MGC119879 |
| IFNA13 | interferon, alpha 13 | - |
| IFNA14 | interferon, alpha 14 | LEIF2H, MGC125756, MGC125757 |
| IFNA16 | interferon, alpha 16 | - |
| IFNA17 | interferon, alpha 17 | IFNA, INFA, LEIF2C1 |
| IFNA2 | interferon, alpha 2 | IFNA, INFA2, MGC125764, MGC125765 |
| IFNA21 | interferon, alpha 21 | MGC126687, MGC126689 |
| IFNA4 | interferon, alpha 4 | INFA4, MGC142200 |
| IFNA5 | interferon, alpha 5 | INFA5 |
| IFNA6 | interferon, alpha 6 | - |
| IFNA7 | interferon, alpha 7 | IFNA-J |
| IFNA8 | interferon, alpha 8 | - |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC |
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 | IFN-R, IFN-alpha-REC, IFNABR, IFNARB |
| IFNB1 | interferon, beta 1, fibroblast | IFB, IFF, IFNB, MGC96956 |
| IFNE | interferon, epsilon | IFN-E, IFNE1, IFNT1, MGC119018, MGC119020, PRO655 |
| IFNG | interferon, gamma | IFG, IFI |
| IFNGR1 | interferon gamma receptor 1 | CD119, FLJ45734, IFNGR |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) | AF-1, IFGR2, IFNGT1 |
| IFNK | interferon, kappa | RP11-27J8.1 |
| IFNW1 | interferon, omega 1 | - |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | IGF1A, IGFI |
| IGF1R | insulin-like growth factor 1 receptor | CD221, IGFIR, IGFR, JTK13, MGC142170, MGC142172, MGC18216 |
| IGF2 | insulin-like growth factor 2 (somatomedin A) | C11orf43, FLJ22066, FLJ44734, INSIGF, pp9974 |
| IGF2R | insulin-like growth factor 2 receptor | CD222, CIMPR, M6P-R, MPR1, MPRI |
| IL10 | interleukin 10 | CSIF, IL-10, IL10A, MGC126450, MGC126451, TGIF |
| IL10RA | interleukin 10 receptor, alpha | CDW210A, HIL-10R, IL-10R1, IL10R |
| IL10RB | interleukin 10 receptor, beta | CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2 |
| IL11 | interleukin 11 | AGIF, IL-11 |
| IL11RA | interleukin 11 receptor, alpha | MGC2146 |
| IL11RB | interleukin 11 receptor, beta | - |
| IL12A | interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) | CLMF, IL-12A, NFSK, NKSF1, P35 |
| IL12B | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | CLMF, CLMF2, IL-12B, NKSF, NKSF2 |
| IL12RB1 | interleukin 12 receptor, beta 1 | CD212, IL-12R-BETA1, IL12RB, MGC34454 |
| IL12RB2 | interleukin 12 receptor, beta 2 | - |
| IL13 | interleukin 13 | ALRH, BHR1, IL-13, MGC116786, MGC116788, MGC116789, P600 |
| IL13RA1 | interleukin 13 receptor, alpha 1 | CD213A1, IL-13Ra, NR4 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | CD213A2, CT19, IL-13R, IL13BP |
| IL15 | interleukin 15 | IL-15, MGC9721 |
| IL15RA | interleukin 15 receptor, alpha | MGC104179 |
| IL15RB | interleukin 15 receptor, beta | - |
| IL16 | interleukin 16 (lymphocyte chemoattractant factor) | FLJ16806, FLJ42735, FLJ44234, HsT19289, IL-16, LCF, prIL-16 |
| IL17A | interleukin 17A | CTLA8, IL-17, IL-17A, IL17 |
| IL17B | interleukin 17B | IL-17B, IL-20, MGC138900, MGC138901, ZCYTO7 |
| IL17C | interleukin 17C | CX2, IL-17C, IL-21, MGC126884, MGC138401 |
| IL17D | interleukin 17D | FLJ30846, IL-17D, IL-22, IL-27, IL27 |
| IL17F | interleukin 17F | IL-17F, ML-1, ML1 |
| IL17RA | interleukin 17 receptor A | CD217, CDw217, IL-17RA, IL17R, MGC10262, hIL-17R |
| IL17RB | interleukin 17 receptor B | CRL4, EVI27, IL17BR, IL17RH1, MGC5245 |
| IL17RC | interleukin 17 receptor C | FLJ95963, FLJ96005, IL17-RL, IL17RL, MGC10763 |
| IL17RD | interleukin 17 receptor D | DKFZp434N1928, FLJ35755, IL-17RD, IL17RLM, MGC133309, SEF |
| IL17RE | interleukin 17 receptor E | FLJ23658, MGC71884 |
| IL18 | interleukin 18 (interferon-gamma-inducing factor) | IGIF, IL-18, IL-1g, IL1F4, MGC12320 |
| IL18R1 | interleukin 18 receptor 1 | CD218a, CDw218a, IL-1Rrp, IL18RA, IL1RRP |
| IL18RAP | interleukin 18 receptor accessory protein | ACPL, CD218b, CDw218b, IL18RB, MGC120589, MGC120590 |
| IL19 | interleukin 19 | IL-10C, MDA1, NG.1, ZMDA1 |
| IL1A | interleukin 1, alpha | IL-1A, IL1, IL1-ALPHA, IL1F1 |
| IL1B | interleukin 1, beta | IL-1, IL1-BETA, IL1F2 |
| IL1F10 | interleukin 1 family, member 10 (theta) | FIL1-theta, FKSG75, IL-1HY2, IL1-theta, MGC119831, MGC119832, MGC119833 |
| IL1F5 | interleukin 1 family, member 5 (delta) | FIL1, FIL1(DELTA), FIL1D, IL1HY1, IL1L1, IL1RP3, MGC29840 |
| IL1F6 | interleukin 1 family, member 6 (epsilon) | FIL1, FIL1(EPSILON), FIL1E, IL-1F6, IL1(EPSILON), MGC129552, MGC129553 |
| IL1F7 | interleukin 1 family, member 7 (zeta) | FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H4, IL-1RP1, IL1H4, IL1RP1 |
| IL1F8 | interleukin 1 family, member 8 (eta) | FIL1, FIL1-(ETA), FIL1H, IL-1F8, IL-1H2, IL1-ETA, IL1H2, MGC126880, MGC126882 |
| IL1F9 | interleukin 1 family, member 9 | IL-1F9, IL-1H1, IL-1RP2, IL1E, IL1H1, IL1RP2 |
| IL1R1 | interleukin 1 receptor, type I | CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80 |
| IL1R2 | interleukin 1 receptor, type II | CD121b, IL1RB, MGC47725 |
| IL1RAP | interleukin 1 receptor accessory protein | C3orf13, FLJ37788, IL-1RAcP, IL1R3 |
| IL1RL1 | interleukin 1 receptor-like 1 | DER4, FIT-1, MGC32623, ST2, ST2L, ST2V, T1 |
| IL1RL2 | interleukin 1 receptor-like 2 | IL1R-rp2, IL1RRP2 |
| IL1RN | interleukin 1 receptor antagonist | ICIL-1RA, IL-1ra3, IL1F3, IL1RA, IRAP, MGC10430 |
| IL2 | interleukin 2 | IL-2, TCGF, lymphokine |
| IL20 | interleukin 20 | IL-20, IL10D, MGC96907, ZCYTO10 |
| IL20RA | interleukin 20 receptor, alpha | FLJ40993, IL-20R1, ZCYTOR7 |
| IL20RB | interleukin 20 receptor beta | DIRS1, FNDC6, IL-20R2, MGC34923 |
| IL21 | interleukin 21 | IL-21, Za11 |
| IL21R | interleukin 21 receptor | MGC10967, NILR |
| IL22 | interleukin 22 | IL-21, IL-22, IL-D110, IL-TIF, IL21, ILTIF, MGC79382, MGC79384, TIFIL-23, TIFa, zcyto18 |
| IL22RA1 | interleukin 22 receptor, alpha 1 | CRF2-9, IL22R, IL22R1 |
| IL22RA2 | interleukin 22 receptor, alpha 2 | CRF2-10, CRF2-S1, CRF2X, IL-22BP, MGC150509, MGC150510 |
| IL23A | interleukin 23, alpha subunit p19 | IL-23, IL-23A, IL23P19, MGC79388, P19, SGRF |
| IL23R | interleukin 23 receptor | - |
| IL24 | interleukin 24 | C49A, FISP, IL-24, IL10B, MDA7, Mob-5, ST16, mda-7 |
| IL25 | interleukin 25 | IL-17E, IL-25, IL17E |
| IL26 | interleukin 26 | AK155, IL-26 |
| IL27 | interleukin 27 | IL-27, IL-27A, IL27p28, IL30, MGC71873, p28 |
| IL27RA | interleukin 27 receptor, alpha | CRL1, IL27R, TCCR, WSX1, zcytor1 |
| IL28A | interleukin 28A (interferon, lambda 2) | IFNL2, IL-28A |
| IL28B | interleukin 28B (interferon, lambda 3) | IFNL3, IL-28B, IL28C |
| IL28RA | interleukin 28 receptor, alpha (interferon, lambda receptor) | CRF2/12, IFNLR, IFNLR1, IL-28R1, LICR2 |
| IL29 | interleukin 29 (interferon, lambda 1) | IFNL1, IL-29 |
| IL2RA | interleukin 2 receptor, alpha | CD25, IDDM10, IL2R, TCGFR |
| IL2RB | interleukin 2 receptor, beta | CD122, P70-75 |
| IL2RG | interleukin 2 receptor, gamma (severe combined immunodeficiency) | CD132, IMD4, SCIDX, SCIDX1 |
| IL3 | interleukin 3 (colony-stimulating factor, multiple) | IL-3, MCGF, MGC79398, MGC79399, MULTI-CSF |
| IL31 | interleukin 31 | IL-31 |
| IL31RA | interleukin 31 receptor A | CRL, CRL3, GLM-R, GLMR, GPL, IL-31RA, MGC125346, PRO21384 |
| IL32 | interleukin 32 | IL-32alpha, IL-32beta, IL-32delta, IL-32gamma, NK4, TAIF, TAIFa, TAIFb, TAIFc, TAIFd |
| IL33 | interleukin 33 | C9orf26, DKFZp586H0523, DVS27, NF-HEV, NFEHEV, RP11-575C20.2 |
| IL34 | interleukin 34 | C16orf77, IL-34, MGC34647 |
| IL3RA | interleukin 3 receptor, alpha (low affinity) | CD123, IL3R, IL3RAY, IL3RX, IL3RY, MGC34174, hIL-3Ra |
| IL4 | interleukin 4 | BCGF-1, BCGF1, BSF1, IL-4, MGC79402 |
| IL4R | interleukin 4 receptor | CD124, IL4RA |
| IL5 | interleukin 5 (colony-stimulating factor, eosinophil) | EDF, IL-5, TRF |
| IL5RA | interleukin 5 receptor, alpha | CD125, CDw125, HSIL5R3, IL5R, MGC26560 |
| IL6 | interleukin 6 (interferon, beta 2) | BSF2, HGF, HSF, IFNB2, IL-6 |
| IL6R | interleukin 6 receptor | CD126, IL-6R-1, IL-6R-alpha, IL6RA, MGC104991 |
| IL6ST | interleukin 6 signal transducer (gp130, oncostatin M receptor) | CD130, CDw130, GP130, GP130-RAPS, IL6R-beta |
| IL7 | interleukin 7 | IL-7 |
| IL7R | interleukin 7 receptor | CD127, CDW127, IL-7R-alpha, IL7RA, ILRA |
| IL8 | interleukin 8 | CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 |
| IL8RA | interleukin 8 receptor, alpha | C-C, C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, CXCR1, IL8R1, IL8RBA |
| IL8RB | interleukin 8 receptor, beta | CD182, CDw128b, CMKAR2, CXCR2, IL8R2, IL8RA |
| IL9 | interleukin 9 | HP40, IL-9, P40 |
| IL9R | interleukin 9 receptor | CD129 |
| INHA | inhibin, alpha | - |
| INHBA | inhibin, beta A | EDF, FRP |
| INHBB | inhibin, beta B | MGC157939 |
| INHBC | inhibin, beta C | IHBC |
| INHBE | inhibin, beta E | MGC4638 |
| INS | insulin | ILPR, IRDN |
| INS-IGF2 | INS-IGF2 readthrough transcript | - |
| INSL3 | insulin-like 3 (Leydig cell) | MGC119818, MGC119819, RLF, RLNL |
| INSL4 | insulin-like 4 (placenta) | EPIL, PLACENTIN |
| INSL5 | insulin-like 5 | MGC126695, MGC126697, PRO182, UNQ156 |
| INSL6 | insulin-like 6 | RIF1 |
| INSR | insulin receptor | CD220, HHF5 |
| JAG1 | jagged 1 (Alagille syndrome) | AGS, AHD, AWS, CD339, HJ1, JAGL1, MGC104644 |
| JAG2 | jagged 2 | HJ2, SER2 |
| KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) | CD309, FLK1, VEGFR, VEGFR2 |
| KGFLP1 | keratinocyte growth factor-like protein 1 | MGC125746, MGC125747, MGC126891 |
| KGFLP2 | keratinocyte growth factor-like protein 2 | - |
| KITLG | KIT ligand | DKFZp686F2250, KL-1, Kitl, MGF, SCF, SF, SHEP7 |
| KL | klotho | - |
| LACRT | lacritin | MGC71934 |
| LECT2 | leukocyte cell-derived chemotaxin 2 | MGC126628, chm-II, chm2 |
| LEFTY1 | left-right determination factor 1 | LEFTB, LEFTYB |
| LEFTY2 | left-right determination factor 2 | EBAF, LEFTA, LEFTYA, MGC46222, TGFB4 |
| LEP | leptin | FLJ94114, OB, OBS |
| LEPR | leptin receptor | CD295, OBR |
| LGR4 | leucine-rich repeat-containing G protein-coupled receptor 4 | GPR48 |
| LGR5 | leucine-rich repeat-containing G protein-coupled receptor 5 | FEX, GPR49, GPR67, GRP49, HG38, MGC117008 |
| LGR6 | leucine-rich repeat-containing G protein-coupled receptor 6 | FLJ14471, GPCR, VTS20631 |
| LHB | luteinizing hormone beta polypeptide | CGB4, LSH-B, hLHB |
| LHCGR | luteinizing hormone/choriogonadotropin receptor | FLJ41504, LCGR, LGR2, LH/CG-R, LH/CGR, LHR, LHRHR, LSH-R |
| LIF | leukemia inhibitory factor (cholinergic differentiation factor) | CDF, DIA, HILDA |
| LIFR | leukemia inhibitory factor receptor alpha | CD118, FLJ98106, FLJ99923, LIF-R, SJS2, STWS, SWS |
| LRSAM1 | leucine rich repeat and sterile alpha motif containing 1 | FLJ31641, RIFLE, TAL |
| LTA | lymphotoxin alpha (TNF superfamily, member 1) | LT, TNFB, TNFSF1 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | TNFC, TNFSF3, p33 |
| LTB4R | leukotriene B4 receptor | BLT1, BLTR, CMKRL1, GPR16, LTB4R1, LTBR1, P2RY7, P2Y7 |
| LTB4R2 | leukotriene B4 receptor 2 | BLT2, BLTR2, JULF2, KPG_004, NOP9 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | MGC163161 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | C14orf141, LTBP3, MSTP031 |
| LTBP3 | latent transforming growth factor beta binding protein 3 | DKFZp586M2123, FLJ33431, FLJ39893, FLJ42533, FLJ44138, FLJ45576, LTBP-3, LTBP2, pp6425 |
| LTBP4 | latent transforming growth factor beta binding protein 4 | FLJ46318, FLJ90018, LTBP-4, LTBP-4L |
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) | CD18, D12S370, LT-BETA-R, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFRSF3 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) | MGC14337, MSH-R, SHEP2 |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) | ACTHR, MGC125798 |
| MC3R | melanocortin 3 receptor | BMIQ9, MC3, MC3-R, OB20, OQTL |
| MC4R | melanocortin 4 receptor | MGC126851, MGC138197 |
| MCHR1 | melanin-concentrating hormone receptor 1 | GPR24, MCH1R, MGC32129, SLC1 |
| MCHR2 | melanin-concentrating hormone receptor 2 | GPR145, MCH2, MCH2R, SLT |
| MDK | midkine (neurite growth-promoting factor 2) | FLJ27379, MK, NEGF2 |
| MET | met proto-oncogene (hepatocyte growth factor receptor) | AUTS9, HGFR, RCCP2, c-Met |
| MIA | melanoma inhibitory activity | CD-RAP |
| MIF | macrophage migration inhibitory factor (glycosylation-inhibiting factor) | GIF, GLIF, MMIF |
| MLN | motilin | MGC138519 |
| MLNR | motilin receptor | GPR38, MTLR1 |
| MPL | myeloproliferative leukemia virus oncogene | C-MPL, CD110, MPLV, TPOR |
| MSTN | myostatin | GDF8 |
| MTNR1A | melatonin receptor 1A | MEL-1A-R, MT1 |
| MTNR1B | melatonin receptor 1B | MEL-1B-R, MT2 |
| NAMPT | nicotinamide phosphoribosyltransferase | 1110035O14Rik, DKFZp666B131, MGC117256, PBEF, PBEF1, VF, VISFATIN |
| NDP | Norrie disease (pseudoglioma) | EVR2, FEVR, ND |
| NENF | neuron derived neurotrophic factor | CIR2, NEUDESIN, SCIRP10, SPUF |
| NGF | nerve growth factor (beta polypeptide) | Beta-NGF, HSAN5, MGC161426, MGC161428, NGFB |
| NGFR | nerve growth factor receptor (TNFR superfamily, member 16) | CD271, Gp80-LNGFR, TNFRSF16, p75(NTR), p75NTR |
| NMB | neuromedin B | MGC17211, MGC2277, MGC3936 |
| NMBR | neuromedin B receptor | - |
| NODAL | nodal homolog (mouse) | MGC138230 |
| NOV | nephroblastoma overexpressed gene | CCN3, IGFBP9 |
| NPFF | neuropeptide FF-amide peptide precursor | FMRFAL |
| NPPA | natriuretic peptide precursor A | ANF, ANP, ATFB6, CDD-ANF, PND |
| NPPB | natriuretic peptide precursor B | BNP |
| NPPC | natriuretic peptide precursor C | CNP |
| NPR1 | natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) | ANPRA, ANPa, GUC2A, GUCY2A, NPRA |
| NPR3 | natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) | ANPRC, GUCY2B, NPRC |
| NPY | neuropeptide Y | PYY4 |
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 | AHC, AHCH, AHX, DAX-1, DAX1, DSS, GTD, HHG, NROB1 |
| NR0B2 | nuclear receptor subfamily 0, group B, member 2 | FLJ17090, SHP, SHP1 |
| NR1D1 | nuclear receptor subfamily 1, group D, member 1 | EAR1, THRA1, THRAL, ear-1, hRev |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | BD73, EAR-1R, RVR |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | LXR-b, LXRB, NER, NER-I, RIP15, UNR |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 | LXR-a, LXRA, RLD-1 |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 | BAR, FXR, HRR-1, HRR1, MGC163445, RIP14 |
| NR1I2 | nuclear receptor subfamily 1, group I, member 2 | BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR |
| NR1I3 | nuclear receptor subfamily 1, group I, member 3 | CAR, CAR1, MB67, MGC150433, MGC97144, MGC97209 |
| NR2C1 | nuclear receptor subfamily 2, group C, member 1 | TR2 |
| NR2C2 | nuclear receptor subfamily 2, group C, member 2 | TAK1, TR2R1, TR4, hTAK1 |
| NR2E1 | nuclear receptor subfamily 2, group E, member 1 | TLL, TLX, XTLL |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 | ESCS, MGC49976, PNR, RNR, RP37, rd7 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | COUP-TFI, EAR-3, EAR3, ERBAL3, NR2F2, SVP44, TCFCOUP1, TFCOUP1 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | ARP1, COUP-TFII, COUPTFB, MGC117452, SVP40, TFCOUP2 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | EAR-2, EAR2, ERBAL2 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | GCCR, GCR, GR, GRL |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | MCR, MGC133092, MLR, MR |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | GFRP1, HMR, MGC9485, N10, NAK-1, NGFIB, NP10, NUR77, TR3 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | HZF-3, NOT, NURR1, RNR1, TINUR |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | CHN, CSMF, MINOR, NOR1, TEC |
| NR5A1 | nuclear receptor subfamily 5, group A, member 1 | AD4BP, ELP, FTZ1, FTZF1, SF-1, SF1 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | B1F, B1F2, CPF, FTF, FTZ-F1, FTZ-F1beta, LRH-1, hB1F, hB1F-2 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | GCNF, GCNF1, NR61, RTR |
| NRG1 | neuregulin 1 | ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, NDF, SMDF |
| NRG2 | neuregulin 2 | Don-1, HRG2, NTAK |
| NRG3 | neuregulin 3 | HRG3, pro-NRG3 |
| NRG4 | neuregulin 4 | DKFZp779N0541, DKFZp779N1944, HRG4 |
| NRP1 | neuropilin 1 | BDCA4, CD304, DKFZp686A03134, DKFZp781F1414, NP1, NRP, VEGF165R |
| NRP2 | neuropilin 2 | MGC126574, NP2, NPN2, PRO2714, VEGF165R2 |
| NRTN | neurturin | NTN |
| NTF3 | neurotrophin 3 | HDNF, MGC129711, NGF-2, NGF2, NT3 |
| NTF4 | neurotrophin 4 | NT-4/5, NT4, NT5, NTF5 |
| NTS | neurotensin | NMN-125, NN, NT, NT/N, NTS1 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 | ASFGF2, FGF-2, FGF-AS, FGF2AS, bFGF, gfg, gfg-1 |
| OGFR | opioid growth factor receptor | - |
| OGN | osteoglycin | DKFZp586P2421, OG, OIF, SLRR3A |
| OPRD1 | opioid receptor, delta 1 | OPRD |
| OPRK1 | opioid receptor, kappa 1 | KOR, OPRK |
| OPRL1 | opiate receptor-like 1 | KOR-3, MGC34578, NOCIR, OOR, ORL1 |
| OPRM1 | opioid receptor, mu 1 | KIAA0403, LMOR, MOR, MOR1, OPRM |
| OSGIN1 | oxidative stress induced growth inhibitor 1 | BDGI, OKL38 |
| OSM | oncostatin M | MGC20461 |
| OSMR | oncostatin M receptor | MGC150626, MGC150627, MGC75127, OSMRB |
| OSTN | osteocrin | MUSCLIN |
| OXT | oxytocin, prepropeptide | MGC126890, MGC126892, OT, OT-NPI |
| OXTR | oxytocin receptor | OT-R |
| P11 | 26 serine protease | MGC133268, PP11, PRSS26 |
| PDGFA | platelet-derived growth factor alpha polypeptide | PDGF-A, PDGF1 |
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | FLJ12858, PDGF2, SIS, SSV, c-sis |
| PDGFC | platelet derived growth factor C | FALLOTEIN, SCDGF |
| PDGFD | platelet derived growth factor D | IEGF, MGC26867, MSTP036, SCDGF-B, SCDGFB |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | CD140A, MGC74795, PDGFR2, Rhe-PDGFRA |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | CD140B, JTK12, PDGF-R-beta, PDGFR, PDGFR1 |
| PDGFRL | platelet-derived growth factor receptor-like | PDGRL, PRLTS |
| PDYN | prodynorphin | MGC26418, PENKB |
| PENK | proenkephalin | - |
| PF4 | platelet factor 4 | CXCL4, MGC138298, SCYB4 |
| PF4V1 | platelet factor 4 variant 1 | CXCL4L1, CXCL4V1, PF4-ALT, PF4A, SCYB4V1 |
| PGF | placental growth factor | D12S1900, PGFL, PLGF, PlGF-2, SHGC-10760 |
| PGR | progesterone receptor | NR3C3, PR |
| PGRMC2 | progesterone receptor membrane component 2 | DG6, PMBP |
| PLAU | plasminogen activator, urokinase | ATF, UPA, URK, u-PA |
| PLAUR | plasminogen activator, urokinase receptor | CD87, UPAR, URKR |
| PLXNA1 | plexin A1 | NOV, NOVP, PLEXIN-A1, PLXN1 |
| PLXNA2 | plexin A2 | FLJ11751, FLJ30634, KIAA0463, OCT, PLXN2 |
| PLXNA3 | plexin A3 | 6.3, HSSEXGENE, PLEXIN-A3, PLXN3, PLXN4, SEX, XAP-6 |
| PLXNA4 | plexin A4 | DKFZp434G0625, DKFZp566O0546, FAYV2820, FLJ35026, FLJ38287, KIAA1550, PLEXA4, PLXNA4A, PLXNA4B, PRO34003 |
| PLXNB1 | plexin B1 | KIAA0407, MGC149167, PLEXIN-B1, PLXN5, SEP |
| PLXNB2 | plexin B2 | KIAA0315, MM1, Nbla00445, PLEXB2, dJ402G11.3 |
| PLXNB3 | plexin B3 | FLJ76953, PLEXB3, PLEXR, PLXN6 |
| PLXNC1 | plexin C1 | CD232, PLXN-C1, VESPR |
| PLXND1 | plexin D1 | KIAA0620, MGC75353, PLEXD1 |
| PMCH | pro-melanin-concentrating hormone | MCH |
| PNOC | prepronociceptin | PPNOC |
| POMC | proopiomelanocortin | ACTH, CLIP, LPH, MSH, NPP, POC |
| PPARA | peroxisome proliferator-activated receptor alpha | MGC2237, MGC2452, NR1C1, PPAR, hPPAR |
| PPARD | peroxisome proliferator-activated receptor delta | FAAR, MGC3931, NR1C2, NUC1, NUCI, NUCII, PPAR-beta, PPARB |
| PPARG | peroxisome proliferator-activated receptor gamma | CIMT1, NR1C3, PPARG1, PPARG2, PPARgamma |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | B-TG1, Beta-TG, CTAP-III, CTAP3, CTAPIII, CXCL7, LA-PF4, LDGF, MDGF, NAP-2, PBP, SCYB7, TC1, TC2, TGB, TGB1, THBGB, THBGB1 |
| PPBPL1 | pro-platelet basic protein-like 1 | TGB2 |
| PPBPL2 | pro-platelet basic protein-like 2 | SPBPBP |
| PPY | pancreatic polypeptide | PNP |
| PRL | prolactin | - |
| PRLH | prolactin releasing hormone | PRH, PRRP |
| PRLHR | prolactin releasing hormone receptor | GPR10, GR3, MGC126539, MGC126541, PrRPR |
| PRLR | prolactin receptor | hPRLrI |
| PROK1 | prokineticin 1 | EGVEGF, PK1, PRK1 |
| PROK2 | prokineticin 2 | BV8, KAL4, MIT1, PK2 |
| PSPN | persephin | PSP |
| PTAFR | platelet-activating factor receptor | PAFR |
| PTGDR | prostaglandin D2 receptor (DP) | AS1, ASRT1, DP, DP1, MGC49004 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | LPGDS, PDS, PGD2, PGDS, PGDS2 |
| PTGER1 | prostaglandin E receptor 1 (subtype EP1), 42kDa | EP1 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa | EP2 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | EP3, EP3-I, EP3-II, EP3-III, EP3-IV, EP3e, MGC141828, MGC141829, MGC27302 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | EP4, EP4R, MGC126583 |
| PTGFR | prostaglandin F receptor (FP) | FP, MGC120498, MGC46203 |
| PTH | parathyroid hormone | PTH1 |
| PTH1R | parathyroid hormone 1 receptor | MGC138426, MGC138452, PFE, PTHR, PTHR1 |
| PTH2 | parathyroid hormone 2 | TIP39 |
| PTH2R | parathyroid hormone 2 receptor | PTHR2 |
| PTHLH | parathyroid hormone-like hormone | HHM, MGC14611, PLP, PTHR, PTHRP |
| PTN | pleiotrophin | HARP, HBGF8, HBNF, NEGF1 |
| PYY | peptide YY | PYY1 |
| QRFP | pyroglutamylated RFamide peptide | 26RFa, MGC119794, P518 |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 | RAB5EP, RABPT5 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | FLJ23282, FRA |
| RARA | retinoic acid receptor, alpha | NR1B1, RAR |
| RARB | retinoic acid receptor, beta | HAP, NR1B2, RRB2 |
| RARG | retinoic acid receptor, gamma | NR1B3, RARC |
| REG1A | regenerating islet-derived 1 alpha | ICRF, MGC12447, P19, PSP, PSPS, PSPS1, PTP, REG |
| RETN | resistin | ADSF, FIZZ3, MGC126603, MGC126609, RETN1, RSTN, XCP1 |
| RETNLB | resistin like beta | FIZZ1, FIZZ2, HXCP2, RELM-beta, RELMb, RELMbeta, XCP2 |
| RLN1 | relaxin 1 | H1, RLXH1, bA12D24.3.1, bA12D24.3.2 |
| RLN2 | relaxin 2 | H2, RLXH2, bA12D24.1.1, bA12D24.1.2 |
| RLN3 | relaxin 3 | H3, RXN3, ZINS4, insl7 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | EDN, RNS2 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | DUTT1, FLJ21882, MGC131599, MGC133277, SAX3 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | KIAA1568, SAX3 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) | FLJ21044, HGPPS, HGPS, RBIG1, RIG1 |
| RORA | RAR-related orphan receptor A | DKFZp686M2414, MGC119326, MGC119329, NR1F1, ROR1, ROR2, ROR3, RZR-ALPHA, RZRA |
| RORB | RAR-related orphan receptor B | NR1F2, ROR-BETA, RZR-BETA, RZRB, bA133M9.1 |
| RORC | RAR-related orphan receptor C | MGC129539, NR1F3, RORG, RZR-GAMMA, RZRG, TOR |
| RXFP1 | relaxin/insulin-like family peptide receptor 1 | LGR7, LGR7.1, LGR7.10, LGR7.2, MGC138347, MGC142177, RXFPR1 |
| RXFP2 | relaxin/insulin-like family peptide receptor 2 | GPR106, GREAT, INSL3R, LGR8, LGR8.1, RXFPR2 |
| RXFP3 | relaxin/insulin-like family peptide receptor 3 | GPCR135, MGC141998, MGC142000, RLN3R1, RXFPR3, SALPR |
| RXRA | retinoid X receptor, alpha | FLJ00280, FLJ00318, FLJ16020, FLJ16733, MGC102720, NR2B1 |
| RXRB | retinoid X receptor, beta | DAUDI6, H-2RIIBP, MGC1831, NR2B2, RCoR-1 |
| RXRG | retinoid X receptor, gamma | NR2B3, RXRC |
| S100A6 | S100 calcium binding protein A6 | 2A9, 5B10, CABP, CACY, PRA |
| S1PR1 | sphingosine-1-phosphate receptor 1 | CHEDG1, D1S3362, ECGF1, EDG-1, EDG1, FLJ58121, S1P1 |
| S1PR2 | sphingosine-1-phosphate receptor 2 | AGR16, EDG-5, EDG5, Gpcr13, H218, LPB2, S1P2 |
| SAA1 | serum amyloid A1 | MGC111216, PIG4, SAA, TP53I4 |
| SAA2 | serum amyloid A2 | - |
| SBDS | Shwachman-Bodian-Diamond syndrome | CGI-97, FLJ10917, SDS, SWDS |
| SCG2 | secretogranin II (chromogranin C) | CHGC, SN, SgII |
| SCGB3A1 | secretoglobin, family 3A, member 1 | HIN-1, HIN1, LU105, MGC87867, PnSP-2, UGRP2 |
| SCT | secretin | - |
| SCTR | secretin receptor | SR |
| SCYE1 | small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) | AIMP1, EMAP2, EMAPII, p43 |
| SDC1 | syndecan 1 | CD138, SDC, SYND1, syndecan |
| SDC2 | syndecan 2 | HSPG, HSPG1, SYND2 |
| SDC3 | syndecan 3 | N-syndecan, SDCN, SYND3 |
| SDC4 | syndecan 4 | MGC22217, SYND4 |
| SECTM1 | secreted and transmembrane 1 | K12 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | Hsema-I, Hsema-III, MGC133243, SEMA1, SEMAD, SEMAIII, SEMAL, SemD, coll-1 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | FLJ34863, LUCA-1, SEMA5, SEMAA, SemA, semaV |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | SEMAE, SemE |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | MGC39708, Sema-Z2, coll-2 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | KIAA0331, M-SEMAH, M-SemaK, SEMAH, coll-5 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F | SEMA-IV, SEMA4, SEMAK |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G | FLJ00014, MGC119473, sem2 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | CORD10, FLJ12287, RP35, SEMAB, SEMB |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | KIAA1745, MGC131831, SEMAC, SemC |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | FLJ20369, KIAA1739, M-SEMA-F, MGC126382, MGC126383, SEMACL1, SEMAF, SEMAI |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | C9orf164, CD100, FLJ33485, FLJ34282, FLJ39737, FLJ46484, M-sema-G, MGC169138, MGC169141, SEMAJ, coll-4 |
| SEMA4F | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F | M-SEMA, PRO2353, SEMAM, SEMAW, m-Sema-M |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G | FLJ20590, KIAA1619, MGC102867 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | FLJ12815, SEMAF, semF |
| SEMA5B | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B | FLJ10372, KIAA1445, SEMAG, SemG |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | HT018, KIAA1368, SEMA, SEMA6A1, SEMAQ, VIA |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B | SEM-SEMA-Y, SEMA-VIB, SEMAN, semaZ |
| SEMA6C | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C | SEMAY, m-SemaY, m-SemaY2 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D | FLJ11598, KIAA1479 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) | CD108, CDw108, H-SEMA-K1, H-Sema-L, JMH, MGC126692, MGC126696, SEMAK1, SEMAL |
| SLIT1 | slit homolog 1 (Drosophila) | MEGF4, MGC164811, SLIL1, SLIT3, Slit-1 |
| SLIT2 | slit homolog 2 (Drosophila) | FLJ14420, SLIL3, Slit-2 |
| SLURP1 | secreted LY6/PLAUR domain containing 1 | ANUP, ARS, ArsB, LY6LS, MDM |
| SORT1 | sortilin 1 | Gp95, NT3 |
| SPP1 | secreted phosphoprotein 1 | BNSP, BSPI, ETA-1, MGC110940, OPN |
| SST | somatostatin | SMST |
| SSTR1 | somatostatin receptor 1 | SRIF-2 |
| SSTR2 | somatostatin receptor 2 | - |
| SSTR5 | somatostatin receptor 5 | - |
| ST2 | suppression of tumorigenicity 2 | - |
| STC1 | stanniocalcin 1 | STC |
| STC2 | stanniocalcin 2 | STC-2, STCRP |
| TAC1 | tachykinin, precursor 1 | Hs.2563, NK2, NKNA, NPK, TAC2 |
| TACR1 | tachykinin receptor 1 | NK1R, NKIR, SPR, TAC1R |
| TDGF1 | teratocarcinoma-derived growth factor 1 | CR, CRGF, CRIPTO, Cripto-1 |
| TDGF3 | teratocarcinoma-derived growth factor 3, pseudogene | CR-3, CRIPTO, CRIPTO-3, TDGF1, TDGF2 |
| TEK | TEK tyrosine kinase, endothelial | CD202B, TIE-2, TIE2, VMCM, VMCM1 |
| TG | thyroglobulin | AITD3, TGN |
| TGFA | transforming growth factor, alpha | TFGA |
| TGFB1 | transforming growth factor, beta 1 | CED, DPD1, TGFB, TGFbeta |
| TGFB2 | transforming growth factor, beta 2 | MGC116892, TGF-beta2 |
| TGFB3 | transforming growth factor, beta 3 | ARVD, FLJ16571, TGF-beta3 |
| TGFBR1 | transforming growth factor, beta receptor 1 | AAT5, ACVRLK4, ALK-5, ALK5, LDS1A, LDS2A, SKR4, TGFR-1 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | AAT3, FAA3, LDS1B, LDS2B, MFS2, RIIC, TAAD2, TGFR-2, TGFbeta-RII |
| TGFBR3 | transforming growth factor, beta receptor III | BGCAN, betaglycan |
| THPO | thrombopoietin | MGC163194, MGDF, MKCSF, ML, MPLLG, TPO |
| THRA | thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) | AR7, EAR7, ERB-T-1, ERBA, ERBA1, MGC000261, MGC43240, NR1A1, THRA1, THRA2, c-ERBA-1 |
| THRB | thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian) | ERBA-BETA, ERBA2, GRTH, MGC126109, MGC126110, NR1A2, PRTH, THR1, THRB1, THRB2 |
| TIE1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | JTK14, TIE |
| TNC | tenascin C | HXB, MGC167029, TN |
| TNF | tumor necrosis factor (TNF superfamily, member 2) | DIF, TNF-alpha, TNFA, TNFSF2 |
| TNFRSF10A | tumor necrosis factor receptor superfamily, member 10a | APO2, CD261, DR4, MGC9365, TRAILR-1, TRAILR1 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9 |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain | CD263, DCR1, LIT, MGC149501, MGC149502, TRAILR3, TRID |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | CD264, DCR2, TRAILR4, TRUNDD |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator | CD265, FEO, LOH18CR1, ODFR, OFE, OPTB7, OSTS, PDB2, RANK, TRANCER |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | MGC29565, OCIF, OPG, TR1 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | CD266, FN14, TWEAKR |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B | CD267, CVID, FLJ39942, MGC133214, MGC39952, TACI, TNFRSF14B |
| TNFRSF13C | tumor necrosis factor receptor superfamily, member 13C | BAFF-R, BAFFR, CD268, MGC138235 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) | ATAR, HVEA, HVEM, LIGHTR, TR2 |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 | BCM, BCMA, CD269 |
| TNFRSF18 | tumor necrosis factor receptor superfamily, member 18 | AITR, GITR, GITR-D |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | TAJ, TAJ-alpha, TRADE, TROY |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | CD120a, FPF, MGC19588, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR55, TNFR60, p55, p55-R, p60 |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | BM-018, DR6, MGC31965 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 | APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR |
| TNFRSF4 | tumor necrosis factor receptor superfamily, member 4 | ACT35, CD134, OX40, TXGP1L |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | DCR3, DJ583P15.1.1, M68, TR6 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 | CD30, D1S166E, Ki-1 |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 4-1BB, CD137, CDw137, ILA, MGC2172 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | APO2L, Apo-2L, CD253, TL2, TRAIL |
| TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 | CD254, ODF, OPGL, OPTB2, RANKL, TRANCE, hRANKL2, sOdf |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 | APO3L, DR3LG, MGC129581, MGC20669, TWEAK |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 | APRIL, CD256, TALL2, TRDL-1, UNQ383/PRO715, ligand |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | BAFF, BLYS, CD257, DTL, TALL-1, TALL1, THANK, TNFSF20, ZTNF4 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | CD258, HVEML, LIGHT, LTg, TR2 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 | MGC129934, MGC129935, TL1, TL1A, VEGI, VEGI192A |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 | AITRL, GITRL, MGC138237, TL6, hGITRL |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | CD134L, CD252, GP34, OX-40L, OX4OL, TXGP1 |
| TNFSF8 | tumor necrosis factor (ligand) superfamily, member 8 | CD153, CD30L, CD30LG, MGC138144 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | 4-1BB-L, CD137L |
| TOR2A | torsin family 2, member A | FLJ14771, MGC99558, TORP1 |
| TRH | thyrotropin-releasing hormone | MGC125964, MGC125965 |
| TRHR | thyrotropin-releasing hormone receptor | MGC141920 |
| TSHB | thyroid stimulating hormone, beta | CHNG4, TSH-BETA |
| TSHR | thyroid stimulating hormone receptor | CHNG1, LGR3, MGC75129, hTSHR-I |
| TSLP | thymic stromal lymphopoietin | - |
| TUBB3 | tubulin, beta 3 | MC1R, TUBB4, beta-4 |
| TXLNA | taxilin alpha | DKFZp451J0118, IL14, MGC118870, MGC118871, RP4-622L5.4, TXLN |
| TYMP | thymidine phosphorylase | ECGF1, MNGIE, PDECGF, TP, hPD-ECGF |
| UCN | urocortin | MGC129974, MGC129975, UI, UROC |
| UCN2 | urocortin 2 | SRP, UCN-II, UCNI, UR, URP |
| UCN3 | urocortin 3 (stresscopin) | MGC119002, SCP, SPC, UCNIII |
| UTS2 | urotensin 2 | PRO1068, U-II, UCN2, UII |
| UTS2D | urotensin 2 domain containing | MGC138371, U2B, URP |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | NR1I1 |
| VEGFA | vascular endothelial growth factor A | MGC70609, MVCD1, VEGF, VEGF-A, VPF |
| VEGFB | vascular endothelial growth factor B | VEGFL, VRF |
| VEGFC | vascular endothelial growth factor C | Flt4-L, VRP |
| VGF | VGF nerve growth factor inducible | - |
| VIP | vasoactive intestinal peptide | MGC13587, PHM27 |
| VIPR1 | vasoactive intestinal peptide receptor 1 | FLJ41949, HVR1, II, PACAP-R-2, RDC1, VAPC1, VIPR, VIRG, VPAC1, VPCAP1R |
| VIPR2 | vasoactive intestinal peptide receptor 2 | FLJ16511, VPAC2, VPCAP2R |
| XCL1 | chemokine (C motif) ligand 1 | ATAC, LPTN, LTN, SCM-1, SCM-1a, SCM1, SCYC1 |
| XCL2 | chemokine (C motif) ligand 2 | SCM-1b, SCM1B, SCYC2 |
| XCR1 | chemokine (C motif) receptor 1 | CCXCR1, GPR5 |
Interferons
The interferon family of signaling proteins consists of Type I, Type II, and Type III interferons. They trigger the defensive responses of the immune system upon infection with virus and, like other cytokines, enable communication between cells of the immune system.
| Symbol | Name | Synonyms |
|---|---|---|
| IFNA10 | interferon, alpha 10 | MGC119878, MGC119879 |
| IFNA13 | interferon, alpha 13 | - |
| IFNA14 | interferon, alpha 14 | LEIF2H, MGC125756, MGC125757 |
| IFNA16 | interferon, alpha 16 | - |
| IFNA17 | interferon, alpha 17 | IFNA, INFA, LEIF2C1 |
| IFNA2 | interferon, alpha 2 | IFNA, INFA2, MGC125764, MGC125765 |
| IFNA21 | interferon, alpha 21 | MGC126687, MGC126689 |
| IFNA4 | interferon, alpha 4 | INFA4, MGC142200 |
| IFNA5 | interferon, alpha 5 | INFA5 |
| IFNA6 | interferon, alpha 6 | - |
| IFNA7 | interferon, alpha 7 | IFNA-J |
| IFNA8 | interferon, alpha 8 | - |
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 | IFN-R, IFN-alpha-REC, IFNABR, IFNARB |
| IFNB1 | interferon, beta 1, fibroblast | IFB, IFF, IFNB, MGC96956 |
| IFNE | interferon, epsilon | IFN-E, IFNE1, IFNT1, MGC119018, MGC119020, PRO655 |
| IFNG | interferon, gamma | IFG, IFI |
| IFNGR1 | interferon gamma receptor 1 | CD119, FLJ45734, IFNGR |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) | AF-1, IFGR2, IFNGT1 |
| IFNK | interferon, kappa | RP11-27J8.1 |
| IFNW1 | interferon, omega 1 | - |
Interleukins
Interleukins are cytokines that are secreted by immune cells and coordinate communication between immune cells over the course of an immune response. Over 60 interleukins have been described.
| Symbol | Name | Synonyms |
|---|---|---|
| EBI3 | Epstein-Barr Virus Induced 3 | IL35B, IL27B, IL35 subunit |
| IL10RA | interleukin 10 receptor, alpha | CDW210A, HIL-10R, IL-10R1, IL10R |
| IL10RB | interleukin 10 receptor, beta | CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2 |
| IL11 | interleukin 11 | AGIF, IL-11 |
| IL11RA | interleukin 11 receptor, alpha | MGC2146 |
| IL11RB | interleukin 11 receptor, beta | - |
| IL12A | interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) | CLMF, IL-12A, NFSK, NKSF1, P35 |
| IL12B | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | CLMF, CLMF2, IL-12B, NKSF, NKSF2 |
| IL12RB1 | interleukin 12 receptor, beta 1 | CD212, IL-12R-BETA1, IL12RB, MGC34454 |
| IL12RB2 | interleukin 12 receptor, beta 2 | - |
| IL13 | interleukin 13 | ALRH, BHR1, IL-13, MGC116786, MGC116788, MGC116789, P600 |
| IL13RA1 | interleukin 13 receptor, alpha 1 | CD213A1, IL-13Ra, NR4 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | CD213A2, CT19, IL-13R, IL13BP |
| IL15 | interleukin 15 | IL-15, MGC9721 |
| IL15RA | interleukin 15 receptor, alpha | MGC104179 |
| IL15RB | interleukin 15 receptor, beta | - |
| IL16 | interleukin 16 (lymphocyte chemoattractant factor) | FLJ16806, FLJ42735, FLJ44234, HsT19289, IL-16, LCF, prIL-16 |
| IL17A | interleukin 17A | CTLA8, IL-17, IL-17A, IL17 |
| IL17B | interleukin 17B | IL-17B, IL-20, MGC138900, MGC138901, ZCYTO7 |
| IL17C | interleukin 17C | CX2, IL-17C, IL-21, MGC126884, MGC138401 |
| IL17D | interleukin 17D | FLJ30846, IL-17D, IL-22, IL-27, IL27 |
| IL17F | interleukin 17F | IL-17F, ML-1, ML1 |
| IL17RA | interleukin 17 receptor A | CD217, CDw217, IL-17RA, IL17R, MGC10262, hIL-17R |
| IL17RB | interleukin 17 receptor B | CRL4, EVI27, IL17BR, IL17RH1, MGC5245 |
| IL17RC | interleukin 17 receptor C | FLJ95963, FLJ96005, IL17-RL, IL17RL, MGC10763 |
| IL17RD | interleukin 17 receptor D | DKFZp434N1928, FLJ35755, IL-17RD, IL17RLM, MGC133309, SEF |
| IL17RE | interleukin 17 receptor E | FLJ23658, MGC71884 |
| IL18 | interleukin 18 (interferon-gamma-inducing factor) | IGIF, IL-18, IL-1g, IL1F4, MGC12320 |
| IL18R1 | interleukin 18 receptor 1 | CD218a, CDw218a, IL-1Rrp, IL18RA, IL1RRP |
| IL18RAP | interleukin 18 receptor accessory protein | ACPL, CD218b, CDw218b, IL18RB, MGC120589, MGC120590 |
| IL19 | interleukin 19 | IL-10C, MDA1, NG.1, ZMDA1 |
| IL1A | interleukin 1, alpha | IL-1A, IL1, IL1-ALPHA, IL1F1 |
| IL1B | interleukin 1, beta | IL-1, IL1-BETA, IL1F2 |
| IL1F10 | interleukin 1 family, member 10 (theta) | FIL1-theta, FKSG75, IL-1HY2, IL1-theta, MGC119831, MGC119832, MGC119833, IL38 |
| IL1F5 | interleukin 1 family, member 5 (delta) | FIL1, FIL1(DELTA), FIL1D, IL1HY1, IL1L1, IL1RP3, MGC29840, IL36RN, IL36RA |
| IL1F6 | interleukin 1 family, member 6 (epsilon) | FIL1, FIL1(EPSILON), FIL1E, IL-1F6, IL1(EPSILON), MGC129552, MGC129553, IL36A |
| IL1F7 | interleukin 1 family, member 7 (zeta) | FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H4, IL-1RP1, IL1H4, IL1RP1, IL37 |
| IL1F8 | interleukin 1 family, member 8 (eta) | FIL1, FIL1-(ETA), FIL1H, IL-1F8, IL-1H2, IL1-ETA, IL1H2, MGC126880, MGC126882, IL36B |
| IL1F9 | interleukin 1 family, member 9 | IL-1F9, IL-1H1, IL-1RP2, IL1E, IL1H1, IL1RP2, IL36G |
| IL1R1 | interleukin 1 receptor, type I | CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80 |
| IL1R2 | interleukin 1 receptor, type II | CD121b, IL1RB, MGC47725 |
| IL1RAP | interleukin 1 receptor accessory protein | C3orf13, FLJ37788, IL-1RAcP, IL1R3 |
| IL1RL1 | interleukin 1 receptor-like 1 | DER4, FIT-1, MGC32623, ST2, ST2L, ST2V, T1 |
| IL1RL2 | interleukin 1 receptor-like 2 | IL1R-rp2, IL1RRP2, IL36R |
| IL1RN | interleukin 1 receptor antagonist | ICIL-1RA, IL-1ra3, IL1F3, IL1RA, IRAP, MGC10430 |
| IL2 | interleukin 2 | IL-2, TCGF, lymphokine |
| IL20 | interleukin 20 | IL-20, IL10D, MGC96907, ZCYTO10 |
| IL20RA | interleukin 20 receptor, alpha | FLJ40993, IL-20R1, ZCYTOR7 |
| IL20RB | interleukin 20 receptor beta | DIRS1, FNDC6, IL-20R2, MGC34923 |
| IL21 | interleukin 21 | IL-21, Za11 |
| IL21R | interleukin 21 receptor | MGC10967, NILR |
| IL22 | interleukin 22 | IL-21, IL-22, IL-D110, IL-TIF, IL21, ILTIF, MGC79382, MGC79384, TIFIL-23, TIFa, zcyto18 |
| IL22RA1 | interleukin 22 receptor, alpha 1 | CRF2-9, IL22R, IL22R1 |
| IL22RA2 | interleukin 22 receptor, alpha 2 | CRF2-10, CRF2-S1, CRF2X, IL-22BP, MGC150509, MGC150510 |
| IL23A | interleukin 23, alpha subunit p19 | IL-23, IL-23A, IL23P19, MGC79388, P19, SGRF |
| IL23R | interleukin 23 receptor | - |
| IL24 | interleukin 24 | C49A, FISP, IL-24, IL10B, MDA7, Mob-5, ST16, mda-7 |
| IL25 | interleukin 25 | IL-17E, IL-25, IL17E |
| IL26 | interleukin 26 | AK155, IL-26 |
| IL27 | interleukin 27 | IL-27, IL-27A, IL27p28, IL30, MGC71873, p28 |
| IL27RA | interleukin 27 receptor, alpha | CRL1, IL27R, TCCR, WSX1, zcytor1 |
| IL28A | interleukin 28A (interferon, lambda 2) | IFNL2, IL-28A |
| IL28B | interleukin 28B (interferon, lambda 3) | IFNL3, IL-28B, IL28C |
| IL28RA | interleukin 28 receptor, alpha (interferon, lambda receptor) | CRF2/12, IFNLR, IFNLR1, IL-28R1, LICR2 |
| IL29 | interleukin 29 (interferon, lambda 1) | IFNL1, IL-29 |
| IL2RA | interleukin 2 receptor, alpha | CD25, IDDM10, IL2R, TCGFR |
| IL2RB | interleukin 2 receptor, beta | CD122, P70-75 |
| IL2RG | interleukin 2 receptor, gamma (severe combined immunodeficiency) | CD132, IMD4, SCIDX, SCIDX1 |
| IL3 | interleukin 3 (colony-stimulating factor, multiple) | IL-3, MCGF, MGC79398, MGC79399, MULTI-CSF |
| IL31 | interleukin 31 | IL-31 |
| IL31RA | interleukin 31 receptor A | CRL, CRL3, GLM-R, GLMR, GPL, IL-31RA, MGC125346, PRO21384 |
| IL32 | interleukin 32 | IL-32alpha, IL-32beta, IL-32delta, IL-32gamma, NK4, TAIF, TAIFa, TAIFb, TAIFc, TAIFd |
| IL33 | interleukin 33 | C9orf26, DKFZp586H0523, DVS27, NF-HEV, NFEHEV, RP11-575C20.2 |
| IL34 | interleukin 34 | C16orf77, IL-34, MGC34647 |
| IL3RA | interleukin 3 receptor, alpha (low affinity) | CD123, IL3R, IL3RAY, IL3RX, IL3RY, MGC34174, hIL-3Ra |
| IL4 | interleukin 4 | BCGF-1, BCGF1, BSF1, IL-4, MGC79402 |
| IL4R | interleukin 4 receptor | CD124, IL4RA |
| IL5 | interleukin 5 (colony-stimulating factor, eosinophil) | EDF, IL-5, TRF |
| IL5RA | interleukin 5 receptor, alpha | CD125, CDw125, HSIL5R3, IL5R, MGC26560 |
| IL6 | interleukin 6 (interferon, beta 2) | BSF2, HGF, HSF, IFNB2, IL-6 |
| IL6R | interleukin 6 receptor | CD126, IL-6R-1, IL-6R-alpha, IL6RA, MGC104991 |
| IL6ST | interleukin 6 signal transducer (gp130, oncostatin M receptor) | CD130, CDw130, GP130, GP130-RAPS, IL6R-beta |
| IL7 | interleukin 7 | IL-7 |
| IL7R | interleukin 7 receptor | CD127, CDW127, IL-7R-alpha, IL7RA, ILRA |
| IL8 | interleukin 8 | CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 |
| IL8RA | interleukin 8 receptor, alpha | C-C, C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, CXCR1, IL8R1, IL8RBA |
| IL8RB | interleukin 8 receptor, beta | CD182, CDw128b, CMKAR2, CXCR2, IL8R2, IL8RA |
| IL9 | interleukin 9 | HP40, IL-9, P40 |
| IL9R | interleukin 9 receptor | CD129 |
| ST2 | suppression of tumorigenicity 2 | - |
| TXLNA | taxilin alpha | DKFZp451J0118, IL14, MGC118870, MGC118871, RP4-622L5.4, TXLN |
NK Cell Signaling
Natural killer (NK) cells can kill cells that have been infected by a foreign pathogen. They detect infected cells via receptors such as KIR and NKG2D. Upon activation, NK cells secrete perforin and granzyme B, two enzymes that create pores within an infected cell membrane, triggering cell death.
| Symbol | Name | Synonyms |
|---|---|---|
| ARAF | v-raf murine sarcoma 3611 viral oncogene homolog | A-RAF, ARAF1, PKS2, RAFA1 |
| BID | BH3 interacting domain death agonist | FP497, MGC15319, MGC42355 |
| BRAF | v-raf murine sarcoma viral oncogene homolog B1 | B-RAF1, BRAF1, FLJ95109, MGC126806, MGC138284, RAFB1 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | CPP32, CPP32B, SCA-1 |
| CD244 | CD244 molecule, natural killer cell receptor 2B4 | 2B4, NAIL, NKR2B4, Nmrk, SLAMF4 |
| CD247 | CD247 molecule | CD3-ZETA, CD3H, CD3Q, CD3Z, T3Z, TCRZ |
| CD48 | CD48 molecule | BCM1, BLAST, BLAST1, MEM-102, SLAMF2, hCD48, mCD48 |
| CHP | calcium binding protein P22 | SLC9A1BP |
| CHP2 | calcineurin B homologous protein 2 | - |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) | GMCSF, MGC131935, MGC138897 |
| FAS | Fas (TNF receptor superfamily, member 6) | ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6 |
| FASLG | Fas ligand (TNF superfamily, member 6) | APT1LG1, CD178, CD95L, FASL, TNFSF6 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | FCRG |
| FCGR3A | Fc fragment of IgG, low affinity IIIa, receptor (CD16a) | CD16, CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | CD16, CD16b, FCG3, FCGR3 |
| FYN | FYN oncogene related to SRC, FGR, YES | MGC45350, SLK, SYN |
| GRB2 | growth factor receptor-bound protein 2 | ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT |
| HCST | hematopoietic cell signal transducer | DAP10, DKFZP586C1522, KAP10, PIK3AP |
| HLA-A | major histocompatibility complex, class I, A | FLJ26655, HLAA |
| HLA-B | major histocompatibility complex, class I, B | AS, HLA-B-7301, HLA-B73, HLAB, HLAC, MGC111087, SPDA1 |
| HLA-C | major histocompatibility complex, class I, C | D6S204, FLJ27082, HLA-Cw, HLA-Cw12, HLA-JY3, HLC-C, PSORS1 |
| HLA-E | major histocompatibility complex, class I, E | DKFZp686P19218, EA1.2, EA2.1, HLA-6.2, MHC, QA1 |
| HLA-G | major histocompatibility complex, class I, G | MHC-G |
| HRAS | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1 |
| ICAM1 | intercellular adhesion molecule 1 | BB2, CD54, P3.58 |
| ICAM2 | intercellular adhesion molecule 2 | CD102 |
| IFNA1 | interferon, alpha 1 | IFL, IFN, IFN-ALPHA, IFNA13, IFNA@, MGC138207, MGC138505, MGC138507 |
| IFNA10 | interferon, alpha 10 | MGC119878, MGC119879 |
| IFNA13 | interferon, alpha 13 | - |
| IFNA14 | interferon, alpha 14 | LEIF2H, MGC125756, MGC125757 |
| IFNA16 | interferon, alpha 16 | - |
| IFNA17 | interferon, alpha 17 | IFNA, INFA, LEIF2C1 |
| IFNA2 | interferon, alpha 2 | IFNA, INFA2, MGC125764, MGC125765 |
| IFNA21 | interferon, alpha 21 | MGC126687, MGC126689 |
| IFNA4 | interferon, alpha 4 | INFA4, MGC142200 |
| IFNA5 | interferon, alpha 5 | INFA5 |
| IFNA6 | interferon, alpha 6 | - |
| IFNA7 | interferon, alpha 7 | IFNA-J |
| IFNA8 | interferon, alpha 8 | - |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC |
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 | IFN-R, IFN-alpha-REC, IFNABR, IFNARB |
| IFNB1 | interferon, beta 1, fibroblast | IFB, IFF, IFNB, MGC96956 |
| IFNG | interferon, gamma | IFG, IFI |
| IFNGR1 | interferon gamma receptor 1 | CD119, FLJ45734, IFNGR |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) | AF-1, IFGR2, IFNGT1 |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | CD11A, LFA-1, LFA1A |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7 |
| KIR2DL1 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 | CD158A, KIR-K64, KIR221, NKAT, NKAT1, p58.1 |
| KIR2DL2 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 | CD158B1, CD158b, NKAT6, p58.2 |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 | CD158B2, CD158b, GL183, KIR-023GB, KIR-K7b, KIR-K7c, KIRCL23, MGC129943, NKAT, NKAT2, NKAT2A, NKAT2B, p58 |
| KIR2DL4 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 | CD158D, G9P, KIR103, KIR103AS |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A | CD158F, KIR2DL5, KIR2DL5.1, KIR2DL5.3 |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 | CD158H, CD158a, p50.1 |
| KIR2DS3 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3 | NKAT7 |
| KIR2DS4 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 | CD158I, KIR1D, KIR412, KKA3, MGC120019, MGC125315, MGC125317, NKAT8 |
| KIR2DS5 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5 | CD158G, NKAT9 |
| KIR3DL1 | killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 | CD158E1, KIR, MGC119726, MGC119728, MGC126589, MGC126591, NKAT3, NKB1, NKB1B |
| KIR3DL2 | killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 | CD158K, MGC125321, NKAT4, NKAT4B, p140 |
| KLRC1 | killer cell lectin-like receptor subfamily C, member 1 | CD159A, MGC13374, MGC59791, NKG2, NKG2A |
| KLRC2 | killer cell lectin-like receptor subfamily C, member 2 | CD159c, MGC138244, NKG2-C, NKG2C |
| KLRC3 | killer cell lectin-like receptor subfamily C, member 3 | NKG2-E, NKG2E |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | CD94 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | CD314, D12S2489E, FLJ17759, FLJ75772, KLR, NKG2-D, NKG2D |
| KRAS | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS3, RASK2 |
| LAT | linker for activation of T cells | LAT1, pp36 |
| LCK | lymphocyte-specific protein tyrosine kinase | YT16, p56lck, pp58lck |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | SLP-76, SLP76 |
| LOC652578 | similar to Fc fragment of IgG, low affinity IIIa, receptor for (CD16) | - |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | MAPKK1, MEK1, MKK1, PRKMK1 |
| MAP2K2 | mitogen-activated protein kinase kinase 2 | FLJ26075, MAPKK2, MEK2, MKK2, PRKMK2 |
| MAPK1 | mitogen-activated protein kinase 1 | ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk |
| MAPK3 | mitogen-activated protein kinase 3 | ERK1, HS44KDAP, HUMKER1A, MGC20180, P44ERK1, P44MAPK, PRKM3 |
| MICA | MHC class I polypeptide-related sequence A | FLJ60820, MGC111087, PERB11.1 |
| MICB | MHC class I polypeptide-related sequence B | PERB11.2 |
| NCR1 | natural cytotoxicity triggering receptor 1 | CD335, FLJ99094, LY94, NK-p46, NKP46 |
| NCR2 | natural cytotoxicity triggering receptor 2 | CD336, LY95, NK-p44, NKP44, dJ149M18.1 |
| NCR3 | natural cytotoxicity triggering receptor 3 | 1C7, CD337, LY117, MALS, NKp30 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | KIAA0827, NF-AT5, NFATL1, NFATZ, OREBP, TONEBP |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 | MGC138448, NF-ATC, NFAT2, NFATc |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | NFAT1, NFATP |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | NFAT4, NFATX |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | NF-ATc4, NFAT3 |
| NRAS | neuroblastoma RAS viral (v-ras) oncogene homolog | ALPS4, N-ras, NRAS1 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | MGC130000, MGC130001, PAKalpha |
| PIK3CA | phosphoinositide-3-kinase, catalytic, alpha polypeptide | MGC142161, MGC142163, PI3K, p110-alpha |
| PIK3CB | phosphoinositide-3-kinase, catalytic, beta polypeptide | DKFZp779K1237, MGC133043, PI3K, PI3KCB, PI3Kbeta, PIK3C1, p110-BETA |
| PIK3CD | phosphoinositide-3-kinase, catalytic, delta polypeptide | p110D |
| PIK3CG | phosphoinositide-3-kinase, catalytic, gamma polypeptide | PI3CG, PI3K, PI3Kgamma, PIK3 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | GRB1, p85, p85-ALPHA |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | P85B, p85, p85-BETA |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | DKFZp686P05226, FLJ41892, p55, p55-GAMMA |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 | F730038I15Rik, FOAP-2, P101-PI3K, p101 |
| PLCG1 | phospholipase C, gamma 1 | PLC-II, PLC1, PLC148, PLCgamma1 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | - |
| PPP3CA | protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform | CALN, CALNA, CALNA1, CCN1, CNA1, PPP2B |
| PPP3CB | protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform | CALNA2, CALNB |
| PPP3CC | protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform | CALNA3 |
| PPP3R1 | protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform | CALNB1, CNB, CNB1 |
| PPP3R2 | protein phosphatase 3 (formerly 2B), regulatory subunit B, beta isoform | PPP3RL |
| PRF1 | perforin 1 (pore forming protein) | FLH2, HPLH2, MGC65093, P1, PFN1, PFP |
| PRKCA | protein kinase C, alpha | AAG6, MGC129900, MGC129901, PKC-alpha, PKCA, PRKACA |
| PRKCB | protein kinase C, beta | MGC41878, PKC-beta, PKCB, PRKCB1, PRKCB2 |
| PRKCG | protein kinase C, gamma | MGC57564, PKC-gamma, PKCC, PKCG, SCA14 |
| PTK2B | PTK2B protein tyrosine kinase 2 beta | CADTK, CAKB, FADK2, FAK2, FRNK, PKB, PTK, PYK2, RAFTK |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | BPTP3, CFC, MGC14433, NS1, PTP-1D, PTP2C, SH-PTP2, SH-PTP3, SHP2 |
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | HCP, HCPH, HPTP1C, PTP-1C, SH-PTP1, SHP-1, SHP-1L, SHP1 |
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | MGC111543, MIG5, TC-25, p21-Rac1 |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | EN-7, Gx, HSPC022 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) | - |
| RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | CRAF, NS5, Raf-1, c-Raf |
| SH2D1A | SH2 domain protein 1A | DSHP, EBVS, FLJ18687, FLJ92177, IMD5, LYP, MTCP1, SAP, XLP, XLPD |
| SH2D1B | SH2 domain containing 1B | EAT2 |
| SH3BP2 | SH3-domain binding protein 2 | 3BP2, CRBM, CRPM, FLJ42079, FLJ54978, RES4-23 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | FLJ26504, SHC, SHCA |
| SHC2 | SHC (Src homology 2 domain containing) transforming protein 2 | SCK, SHCB, SLI |
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | N-Shc, NSHC, RAI, SHCC |
| SHC4 | SHC (Src homology 2 domain containing) family, member 4 | MGC34023, RaLP, SHCD |
| SOS1 | son of sevenless homolog 1 (Drosophila) | GF1, GGF1, GINGF, HGF, NS4 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | FLJ25596 |
| SYK | spleen tyrosine kinase | DKFZp313N1010, FLJ25043, FLJ37489 |
| TNF | tumor necrosis factor (TNF superfamily, member 2) | DIF, TNF-alpha, TNFA, TNFSF2 |
| TNFRSF10A | tumor necrosis factor receptor superfamily, member 10a | APO2, CD261, DR4, MGC9365, TRAILR-1, TRAILR1 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9 |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain | CD263, DCR1, LIT, MGC149501, MGC149502, TRAILR3, TRID |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | CD264, DCR2, TRAILR4, TRUNDD |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | APO2L, Apo-2L, CD253, TL2, TRAIL |
| TYROBP | TYRO protein tyrosine kinase binding protein | DAP12, KARAP, PLOSL |
| ULBP1 | UL16 binding protein 1 | RAET1I |
| ULBP2 | UL16 binding protein 2 | N2DL2, RAET1H |
| ULBP3 | UL16 binding protein 3 | RAET1N |
| VAV1 | vav 1 guanine nucleotide exchange factor | VAV |
| VAV2 | vav 2 guanine nucleotide exchange factor | - |
| VAV3 | vav 3 guanine nucleotide exchange factor | FLJ40431 |
| ZAP70 | zeta-chain (TCR) associated protein kinase 70kDa | FLJ17670, FLJ17679, SRK, STD, TZK, ZAP-70 |
TCR Signaling
The T cell receptor (TCR) engages with antigen presenting cells of the innate immune system. Engagement of the TCR by an MHC molecule presenting its cognate antigen along with co-stimulation activates the T cell, whereas T cell tolerance or anergy are induced when the TCR is engaged without co-stimulation or with a low affinity antigen.
| Symbol | Name | Synonyms |
|---|---|---|
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | PKBB, PKBBETA, PRKBB, RAC-BETA |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) | DKFZp434N0250, PKB-GAMMA, PKBG, PRKBG, RAC-PK-gamma, RAC-gamma, STK-2 |
| BCL10 | B-cell CLL/lymphoma 10 | CARMEN, CIPER, CLAP, c-E10, mE10 |
| CARD11 | caspase recruitment domain family, member 11 | BIMP3, CARMA1, MGC133069 |
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | C-CBL, CBL2, RNF55 |
| CBLB | Cas-Br-M (murine) ecotropic retroviral transforming sequence b | DKFZp686J10223, DKFZp779A0729, DKFZp779F1443, FLJ36865, FLJ41152, Nbla00127, RNF56 |
| CBLC | Cas-Br-M (murine) ecotropic retroviral transforming sequence c | CBL-3, CBL-SL, RNF57 |
| CD247 | CD247 molecule | CD3-ZETA, CD3H, CD3Q, CD3Z, T3Z, TCRZ |
| CD28 | CD28 molecule | MGC138290, Tp44 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | CD3-DELTA, T3D |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | FLJ18683, T3E, TCRE |
| CD3G | CD3g molecule, gamma (CD3-TCR complex) | CD3-GAMMA, FLJ17620, FLJ17664, FLJ79544, FLJ94613, MGC138597, T3G |
| CD4 | CD4 molecule | CD4mut |
| CD40LG | CD40 ligand | CD154, CD40L, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, gp39, hCD40L |
| CD8A | CD8a molecule | CD8, Leu2, MAL, p32 |
| CD8B | CD8b molecule | CD8B1, LYT3, Leu2, Ly3, MGC119115 |
| CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | CDC42Hs, G25K |
| CDK4 | cyclin-dependent kinase 4 | CMM3, MGC14458, PSK-J3 |
| CHP | calcium binding protein P22 | SLC9A1BP |
| CHP2 | calcineurin B homologous protein 2 | - |
| CHUK | conserved helix-loop-helix ubiquitous kinase | IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16 |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) | GMCSF, MGC131935, MGC138897 |
| CTLA4 | cytotoxic T-lymphocyte-associated protein 4 | CD, CD152, CELIAC3, CTLA-4, GSE, ICOS, IDDM12 |
| FOS | v-fos FBJ murine osteosarcoma viral oncogene homolog | AP-1, C-FOS |
| FYN | FYN oncogene related to SRC, FGR, YES | MGC45350, SLK, SYN |
| GRAP2 | GRB2-related adaptor protein 2 | GADS, GRAP-2, GRB2L, GRBLG, GRID, GRPL, GrbX, Grf40, Mona, P38 |
| GRB2 | growth factor receptor-bound protein 2 | ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084 |
| HRAS | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1 |
| ICOS | inducible T-cell co-stimulator | AILIM, CD278, MGC39850 |
| IFNG | interferon, gamma | IFG, IFI |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | FLJ40509, IKK-beta, IKK2, IKKB, MGC131801, NFKBIKB |
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | AMCBX1, FIP-3, FIP3, Fip3p, IKK-gamma, IP, IP1, IP2, IPD2, NEMO |
| IL10 | interleukin 10 | CSIF, IL-10, IL10A, MGC126450, MGC126451, TGIF |
| IL2 | interleukin 2 | IL-2, TCGF, lymphokine |
| IL4 | interleukin 4 | BCGF-1, BCGF1, BSF1, IL-4, MGC79402 |
| IL5 | interleukin 5 (colony-stimulating factor, eosinophil) | EDF, IL-5, TRF |
| ITK | IL2-inducible T-cell kinase | EMT, LYK, MGC126257, MGC126258, PSCTK2 |
| JUN | jun oncogene | AP-1, AP1, c-Jun |
| KRAS | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS3, RASK2 |
| LAT | linker for activation of T cells | LAT1, pp36 |
| LCK | lymphocyte-specific protein tyrosine kinase | YT16, p56lck, pp58lck |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | SLP-76, SLP76 |
| MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | DKFZp434L132, MLT, MLT1 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | FTDCR1B, HS, HSNIK, NIK |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | COT, EST, ESTF, FLJ10486, TPL2, Tpl-2, c-COT |
| NCK1 | NCK adaptor protein 1 | MGC12668, NCK, NCKalpha |
| NCK2 | NCK adaptor protein 2 | GRB4, NCKbeta |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | KIAA0827, NF-AT5, NFATL1, NFATZ, OREBP, TONEBP |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 | MGC138448, NF-ATC, NFAT2, NFATc |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | NFAT1, NFATP |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | NFAT4, NFATX |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | NF-ATc4, NFAT3 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | DKFZp686C01211, EBP-1, KBF1, MGC54151, NF-kappa-B, NFKB-p105, NFKB-p50, p105, p50 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | IKBA, MAD-3, NFKBI |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | IKBB, TRIP9 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | IKBE |
| NRAS | neuroblastoma RAS viral (v-ras) oncogene homolog | ALPS4, N-ras, NRAS1 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | MGC130000, MGC130001, PAKalpha |
| PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 | PAK65, PAKgamma |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 | CDKN1A, MRX30, MRX47, OPHN3, PAK3beta, bPAK, hPAK3 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 | - |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 | PAK5 |
| PAK7 | p21 protein (Cdc42/Rac)-activated kinase 7 | KIAA1264, MGC26232, PAK5 |
| PDCD1 | programmed cell death 1 | CD279, PD1, SLEB2, hPD-1, hPD-l |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 | - |
| PIK3CA | phosphoinositide-3-kinase, catalytic, alpha polypeptide | MGC142161, MGC142163, PI3K, p110-alpha |
| PIK3CB | phosphoinositide-3-kinase, catalytic, beta polypeptide | DKFZp779K1237, MGC133043, PI3K, PI3KCB, PI3Kbeta, PIK3C1, p110-BETA |
| PIK3CD | phosphoinositide-3-kinase, catalytic, delta polypeptide | p110D |
| PIK3CG | phosphoinositide-3-kinase, catalytic, gamma polypeptide | PI3CG, PI3K, PI3Kgamma, PIK3 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | GRB1, p85, p85-ALPHA |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | P85B, p85, p85-BETA |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | DKFZp686P05226, FLJ41892, p55, p55-GAMMA |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 | F730038I15Rik, FOAP-2, P101-PI3K, p101 |
| PLCG1 | phospholipase C, gamma 1 | PLC-II, PLC1, PLC148, PLCgamma1 |
| PPP3CA | protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform | CALN, CALNA, CALNA1, CCN1, CNA1, PPP2B |
| PPP3CB | protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform | CALNA2, CALNB |
| PPP3CC | protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform | CALNA3 |
| PPP3R1 | protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform | CALNB1, CNB, CNB1 |
| PPP3R2 | protein phosphatase 3 (formerly 2B), regulatory subunit B, beta isoform | PPP3RL |
| PRKCQ | protein kinase C, theta | MGC126514, MGC141919, PRKCT, nPKC-theta |
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | HCP, HCPH, HPTP1C, PTP-1C, SH-PTP1, SHP-1, SHP-1L, SHP1 |
| PTPRC | protein tyrosine phosphatase, receptor type, C | B220, CD45, CD45R, GP180, LCA, LY5, T200 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | CALDAG-GEFI, CALDAG-GEFII, MGC129998, MGC129999, RASGRP, V, hRasGRP1 |
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | MGC131774, NFKB3, p65 |
| RHOA | ras homolog gene family, member A | ARH12, ARHA, RHO12, RHOH12 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | GF1, GGF1, GINGF, HGF, NS4 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | FLJ25596 |
| TEC | tec protein tyrosine kinase | MGC126760, MGC126762, PSCTK4 |
| TNF | tumor necrosis factor (TNF superfamily, member 2) | DIF, TNF-alpha, TNFA, TNFSF2 |
| TRAC | T cell receptor alpha constant | - |
| TRAJ1 | T cell receptor alpha joining 1 (non-functional) | - |
| TRAJ10 | T cell receptor alpha joining 10 | - |
| TRAJ11 | T cell receptor alpha joining 11 | - |
| TRAJ12 | T cell receptor alpha joining 12 | - |
| TRAJ13 | T cell receptor alpha joining 13 | - |
| TRAJ14 | T cell receptor alpha joining 14 | - |
| TRAJ15 | T cell receptor alpha joining 15 | - |
| TRAJ16 | T cell receptor alpha joining 16 | - |
| TRAJ17 | T cell receptor alpha joining 17 | - |
| TRAJ18 | T cell receptor alpha joining 18 | - |
| TRAJ19 | T cell receptor alpha joining 19 (non-functional) | - |
| TRAJ2 | T cell receptor alpha joining 2 (non-functional) | - |
| TRAJ20 | T cell receptor alpha joining 20 | - |
| TRAJ21 | T cell receptor alpha joining 21 | - |
| TRAJ22 | T cell receptor alpha joining 22 | - |
| TRAJ23 | T cell receptor alpha joining 23 | - |
| TRAJ24 | T cell receptor alpha joining 24 | - |
| TRAJ25 | T cell receptor alpha joining 25 (non-functional) | - |
| TRAJ26 | T cell receptor alpha joining 26 | - |
| TRAJ27 | T cell receptor alpha joining 27 | - |
| TRAJ28 | T cell receptor alpha joining 28 | - |
| TRAJ29 | T cell receptor alpha joining 29 | - |
| TRAJ3 | T cell receptor alpha joining 3 | - |
| TRAJ30 | T cell receptor alpha joining 30 | - |
| TRAJ31 | T cell receptor alpha joining 31 | - |
| TRAJ32 | T cell receptor alpha joining 32 | - |
| TRAJ33 | T cell receptor alpha joining 33 | - |
| TRAJ34 | T cell receptor alpha joining 34 | - |
| TRAJ35 | T cell receptor alpha joining 35 (non-functional) | - |
| TRAJ36 | T cell receptor alpha joining 36 | - |
| TRAJ37 | T cell receptor alpha joining 37 | - |
| TRAJ38 | T cell receptor alpha joining 38 | - |
| TRAJ39 | T cell receptor alpha joining 39 | - |
| TRAJ4 | T cell receptor alpha joining 4 | - |
| TRAJ40 | T cell receptor alpha joining 40 | - |
| TRAJ41 | T cell receptor alpha joining 41 | - |
| TRAJ42 | T cell receptor alpha joining 42 | - |
| TRAJ43 | T cell receptor alpha joining 43 | - |
| TRAJ44 | T cell receptor alpha joining 44 | - |
| TRAJ45 | T cell receptor alpha joining 45 | - |
| TRAJ46 | T cell receptor alpha joining 46 | - |
| TRAJ47 | T cell receptor alpha joining 47 | - |
| TRAJ48 | T cell receptor alpha joining 48 | - |
| TRAJ49 | T cell receptor alpha joining 49 | - |
| TRAJ5 | T cell receptor alpha joining 5 | - |
| TRAJ50 | T cell receptor alpha joining 50 | - |
| TRAJ52 | T cell receptor alpha joining 52 | - |
| TRAJ53 | T cell receptor alpha joining 53 | - |
| TRAJ54 | T cell receptor alpha joining 54 | - |
| TRAJ56 | T cell receptor alpha joining 56 | - |
| TRAJ57 | T cell receptor alpha joining 57 | - |
| TRAJ58 | T cell receptor alpha joining 58 (non-functional) | - |
| TRAJ59 | T cell receptor alpha joining 59 (non-functional) | - |
| TRAJ6 | T cell receptor alpha joining 6 | - |
| TRAJ61 | T cell receptor alpha joining 61 (non-functional) | - |
| TRAJ7 | T cell receptor alpha joining 7 | - |
| TRAJ8 | T cell receptor alpha joining 8 | - |
| TRAJ9 | T cell receptor alpha joining 9 | - |
| TRAV1-1 | T cell receptor alpha variable 1-1 | TCRAV1S1, TCRAV7S1, TRAV11 |
| TRAV1-2 | T cell receptor alpha variable 1-2 | TCRAV1S2, TCRAV7S2, TRAV12 |
| TRAV10 | T cell receptor alpha variable 10 | TCRAV10S1, TCRAV24S1 |
| TRAV12-1 | T cell receptor alpha variable 12-1 | TCRAV12S1, TCRAV2S3, TRAV121 |
| TRAV12-2 | T cell receptor alpha variable 12-2 | TCRAV12S2, TCRAV2S1, TRAV122 |
| TRAV12-3 | T cell receptor alpha variable 12-3 | TCRAV12S3, TCRAV2S2, TRAV123 |
| TRAV13-1 | T cell receptor alpha variable 13-1 | TCRAV13S1, TCRAV8S1, TRAV131 |
| TRAV13-2 | T cell receptor alpha variable 13-2 | TCRAV13S2, TCRAV8S2, TRAV132 |
| TRAV14DV4 | T cell receptor alpha variable 14/delta variable 4 | TCRAV6S1-hDV104S1, TRAV14/DV4, hADV14S1 |
| TRAV16 | T cell receptor alpha variable 16 | TCRAV16S1, TCRAV9S1 |
| TRAV17 | T cell receptor alpha variable 17 | TCRAV17S1, TCRAV3S1 |
| TRAV18 | T cell receptor alpha variable 18 | TCRAV18S1 |
| TRAV19 | T cell receptor alpha variable 19 | TCRAV12S1, TCRAV19S1 |
| TRAV2 | T cell receptor alpha variable 2 | TCRAV11S1, TCRAV2S1 |
| TRAV20 | T cell receptor alpha variable 20 | TCRAV20S1, TCRAV30S1 |
| TRAV21 | T cell receptor alpha variable 21 | TCRAV21S1, TCRAV23S1 |
| TRAV22 | T cell receptor alpha variable 22 | TCRAV13S1, TCRAV22S1 |
| TRAV23DV6 | T cell receptor alpha variable 23/delta variable 6 | TCRAV17S1, TRAV23/DV6, hADV23S1 |
| TRAV24 | T cell receptor alpha variable 24 | TCRAV18S1, TCRAV24S1 |
| TRAV25 | T cell receptor alpha variable 25 | TCRAV25S1, TCRAV32S1 |
| TRAV26-1 | T cell receptor alpha variable 26-1 | TCRAV26S1, TCRAV4S2, TRAV261 |
| TRAV26-2 | T cell receptor alpha variable 26-2 | TCRAV26S2, TCRAV4S1, TRAV262 |
| TRAV27 | T cell receptor alpha variable 27 | TCRAV10S1, TCRAV27S1 |
| TRAV29DV5 | T cell receptor alpha variable 29/delta variable 5 (gene/pseudogene) | TCRAV21S1, TRAV29/DV5, hADV29S1 |
| TRAV3 | T cell receptor alpha variable 3 (gene/pseudogene) | TCRAV16S1, TCRAV3S1 |
| TRAV30 | T cell receptor alpha variable 30 | TCRAV29S1, TCRAV30S1 |
| TRAV34 | T cell receptor alpha variable 34 | TCRAV26S1, TCRAV34S1 |
| TRAV35 | T cell receptor alpha variable 35 | TCRAV25S1, TCRAV35S1 |
| TRAV36DV7 | T cell receptor alpha variable 36/delta variable 7 | TCRAV28S1, TRAV36/DV7, hADV36S1 |
| TRAV38-1 | T cell receptor alpha variable 38-1 | TCRAV14S2, TCRAV38S1, TRAV381 |
| TRAV38-2DV8 | T cell receptor alpha variable 38-2/delta variable 8 | TCRAV14S1, TRAV382DV8, hADV38S2 |
| TRAV39 | T cell receptor alpha variable 39 | TCRAV27S1, TCRAV39S1 |
| TRAV4 | T cell receptor alpha variable 4 | TCRAV20S1, TCRAV4S1 |
| TRAV40 | T cell receptor alpha variable 40 | TCRAV31S1, TCRAV40S1 |
| TRAV41 | T cell receptor alpha variable 41 | TCRAV19S1, TCRAV41S1 |
| TRAV5 | T cell receptor alpha variable 5 | TCRAV15S1, TCRAV5S1 |
| TRAV6 | T cell receptor alpha variable 6 | TCRAV5S1, TCRAV6S1 |
| TRAV7 | T cell receptor alpha variable 7 | TCRAV7S1 |
| TRAV8-1 | T cell receptor alpha variable 8-1 | TCRAV1S1, TCRAV8S1, TRAV81 |
| TRAV8-2 | T cell receptor alpha variable 8-2 | TCRAV1S5, TCRAV8S2, TRAV82 |
| TRAV8-3 | T cell receptor alpha variable 8-3 | TCRAV1S4, TCRAV8S3, TRAV83 |
| TRAV8-4 | T cell receptor alpha variable 8-4 | TCRAV1S2, TCRAV8S4, TRAV84 |
| TRAV8-6 | T cell receptor alpha variable 8-6 | TCRAV1S3, TCRAV8S6, TRAV86 |
| TRAV8-7 | T cell receptor alpha variable 8-7 (non-functional) | TCRAV8S7, TRAV87 |
| TRAV9-1 | T cell receptor alpha variable 9-1 | TCRAV9S1, TRAV91 |
| TRAV9-2 | T cell receptor alpha variable 9-2 | TCRAV22S1, TCRAV9S2, TRAV92 |
| TRBC1 | T cell receptor beta constant 1 | BV05S1J2.2, MGC88817, TCRBC1 |
| TRBC2 | T cell receptor beta constant 2 | TCRBC2 |
| TRBD1 | T cell receptor beta diversity 1 | TCRBD1 |
| TRBD2 | T cell receptor beta diversity 2 | TCRBD2 |
| TRBJ1-1 | T cell receptor beta joining 1-1 | TCRBJ1S1, TRBJ11 |
| TRBJ1-2 | T cell receptor beta joining 1-2 | TCRBJ1S2, TRBJ12 |
| TRBJ1-3 | T cell receptor beta joining 1-3 | TCRBJ1S3, TRBJ13 |
| TRBJ1-4 | T cell receptor beta joining 1-4 | TCRBJ1S4, TRBJ14 |
| TRBJ1-5 | T cell receptor beta joining 1-5 | TCRBJ1S5, TRBJ15 |
| TRBJ1-6 | T cell receptor beta joining 1-6 | TCRBJ1S6, TRBJ16 |
| TRBJ2-1 | T cell receptor beta joining 2-1 | TCRBJ2S1, TRBJ21 |
| TRBJ2-2 | T cell receptor beta joining 2-2 | TCRBJ2S2, TRBJ22 |
| TRBJ2-3 | T cell receptor beta joining 2-3 | TCRBJ2S3, TRBJ23 |
| TRBJ2-4 | T cell receptor beta joining 2-4 | TCRBJ2S4, TRBJ24 |
| TRBJ2-5 | T cell receptor beta joining 2-5 | TCRBJ2S5, TRBJ25 |
| TRBJ2-6 | T cell receptor beta joining 2-6 | TCRBJ2S6, TRBJ26 |
| TRBJ2-7 | T cell receptor beta joining 2-7 | TCRBJ2S7, TRBJ27 |
| TRBV10-1 | T cell receptor beta variable 10-1(gene/pseudogene) | TCRBV10S1, TCRBV12S2, TCRBV12S2A1T, TRBV101 |
| TRBV10-2 | T cell receptor beta variable 10-2 | TCRBV10S2, TCRBV12S3, TRBV102 |
| TRBV10-3 | T cell receptor beta variable 10-3 | TCRBV10S3, TCRBV12S1A1N2, TRBV103 |
| TRBV11-1 | T cell receptor beta variable 11-1 | TCRBV11S1, TCRBV21S1, TRBV111 |
| TRBV11-2 | T cell receptor beta variable 11-2 | TCRBV11S2, TCRBV21S3A2N2T, TRBV112 |
| TRBV11-3 | T cell receptor beta variable 11-3 | TCRBV11S3, TCRBV21S2A2, TRBV113 |
| TRBV12-3 | T cell receptor beta variable 12-3 | TCRBV12S3, TCRBV8S1, TRBV123 |
| TRBV12-4 | T cell receptor beta variable 12-4 | TCRBV12S4, TCRBV8S2A1T, TRBV124 |
| TRBV12-5 | T cell receptor beta variable 12-5 | TCRBV12S5, TCRBV8S3, TRBV125 |
| TRBV13 | T cell receptor beta variable 13 | TCRBV13S1, TCRBV23S1A2T |
| TRBV14 | T cell receptor beta variable 14 | TCRBV14S1, TCRBV16S1A1N1 |
| TRBV15 | T cell receptor beta variable 15 | TCRBV15S1, TCRBV24S1A3T |
| TRBV16 | T cell receptor beta variable 16 (gene/pseudogene) | TCRBV16S1, TCRBV25S1A2PT |
| TRBV17 | T cell receptor beta variable 17 (non-functional) | TCRBV17S1, TCRBV26S1P |
| TRBV18 | T cell receptor beta variable 18 | TCRBV18S1 |
| TRBV19 | T cell receptor beta variable 19 | TCRBV17S1A1T, TCRBV19S1 |
| TRBV2 | T cell receptor beta variable 2 | TCRBV22S1A2N1T, TCRBV2S1 |
| TRBV20-1 | T cell receptor beta variable 20-1 | TCRBV20S1, TCRBV2S1, TRBV201 |
| TRBV24-1 | T cell receptor beta variable 24-1 | TCRBV15S1, TCRBV24S1, TRBV241 |
| TRBV25-1 | T cell receptor beta variable 25-1 | TCRBV11S1A1T, TCRBV25S1, TRBV251 |
| TRBV27 | T cell receptor beta variable 27 | FLJ35984, TCRBV14S1, TCRBV27S1 |
| TRBV28 | T cell receptor beta variable 28 | TCRBV28S1, TCRBV3S1 |
| TRBV29-1 | T cell receptor beta variable 29-1 | TCRBV29S1, TCRBV4S1A1T, TRBV291 |
| TRBV3-1 | T cell receptor beta variable 3-1 | TCRBV3S1, TCRBV9S1A1T, TRBV31 |
| TRBV30 | T cell receptor beta variable 30 (gene/pseudogene) | TCRBV20S1A1N2, TCRBV30S1 |
| TRBV4-1 | T cell receptor beta variable 4-1 | BV07S1J2.7, TCRBV4S1, TCRBV7S1A1N2T, TRBV41 |
| TRBV4-2 | T cell receptor beta variable 4-2 | TCRBV4S2, TCRBV7S3A2T, TRBV42 |
| TRBV4-3 | T cell receptor beta variable 4-3 | TCRBV4S3, TCRBV7S2A1N4T, TRBV43 |
| TRBV5-1 | T cell receptor beta variable 5-1 | TCRBV5S1, TCRBV5S1A1T, TRBV51 |
| TRBV5-4 | T cell receptor beta variable 5-4 | TCRBV5S4, TCRBV5S6A3N2T, TRBV54 |
| TRBV5-5 | T cell receptor beta variable 5-5 | TCRBV5S3A2T, TCRBV5S5, TRBV55 |
| TRBV5-6 | T cell receptor beta variable 5-6 | TCRBV5S2, TCRBV5S6, TRBV56 |
| TRBV5-7 | T cell receptor beta variable 5-7 (non-functional) | TCRBV5S7, TCRBV5S7P, TRBV57 |
| TRBV5-8 | T cell receptor beta variable 5-8 | TCRBV5S4A2T, TCRBV5S8, TRBV58 |
| TRBV6-1 | T cell receptor beta variable 6-1 | TCRBV13S3, TCRBV6S1, TRBV61 |
| TRBV6-2 | T cell receptor beta variable 6-2 (gene/pseudogene) | TCRBV13S2A1T, TCRBV6S2, TRBV62 |
| TRBV6-3 | T cell receptor beta variable 6-3 | TCRBV13S9/13S2A1T, TCRBV6S3, TRBV63 |
| TRBV6-4 | T cell receptor beta variable 6-4 | TCRBV13S5, TCRBV6S4, TRBV64 |
| TRBV6-5 | T cell receptor beta variable 6-5 | TCRBV13S1, TCRBV6S5, TRBV65 |
| TRBV6-6 | T cell receptor beta variable 6-6 | TCRBV13S6A2T, TCRBV6S6, TRBV66 |
| TRBV6-7 | T cell receptor beta variable 6-7 (non-functional) | TCRBV13S8P, TCRBV6S7, TRBV67 |
| TRBV6-8 | T cell receptor beta variable 6-8 | TCRBV13S7P, TCRBV6S8, TRBV68 |
| TRBV6-9 | T cell receptor beta variable 6-9 | TCRBV13S4, TCRBV6S9, TRBV69 |
| TRBV7-2 | T cell receptor beta variable 7-2 | MGC117435, TCRBV6S5A1N1, TCRBV7S2, TRBV72 |
| TRBV7-3 | T cell receptor beta variable 7-3 | TCRBV6S1A1N1, TCRBV7S3, TRBV73 |
| TRBV7-4 | T cell receptor beta variable 7-4 (gene/pseudogene) | TCRBV6S8A2T, TCRBV7S4, TRBV74 |
| TRBV7-6 | T cell receptor beta variable 7-6 | TCRBV6S3A1N1T, TCRBV7S6, TRBV76 |
| TRBV7-7 | T cell receptor beta variable 7-7 | TCRBV6S6A2T, TCRBV7S7, TRBV77 |
| TRBV7-8 | T cell receptor beta variable 7-8 | TCRBV6S2A1N1T, TCRBV7S8, TRBV78 |
| TRBV7-9 | T cell receptor beta variable 7-9 | TCRBV6S4A1, TCRBV7S9, TRBV79 |
| TRBV9 | T cell receptor beta variable 9 | TCRBV1S1A1N1, TCRBV9S1 |
| TRDC | T cell receptor delta constant | - |
| TRDD1 | T cell receptor delta diversity 1 | - |
| TRDD2 | T cell receptor delta diversity 2 | - |
| TRDD3 | T cell receptor delta diversity 3 | TCRD |
| TRDJ1 | T cell receptor delta joining 1 | TCRD |
| TRDJ2 | T cell receptor delta joining 2 | - |
| TRDJ3 | T cell receptor delta joining 3 | - |
| TRDJ4 | T cell receptor delta joining 4 | - |
| TRDV1 | T cell receptor delta variable 1 | hDV101S1 |
| TRDV2 | T cell receptor delta variable 2 | MGC117421, hDV102S1 |
| TRDV3 | T cell receptor delta variable 3 | hDV103S1 |
| TRGC1 | T cell receptor gamma constant 1 | C1, TCRGC1 |
| TRGC2 | T cell receptor gamma constant 2 | TCRGC2, TRGC2(2X), TRGC2(3X) |
| TRGJ1 | T cell receptor gamma joining 1 | J1, TCRGJ1 |
| TRGJ2 | T cell receptor gamma joining 2 | J2, TCRGJ2 |
| TRGJP | T cell receptor gamma joining P | JP, TCRGJP |
| TRGJP1 | T cell receptor gamma joining P1 | JP1, TCRGJP1 |
| TRGJP2 | T cell receptor gamma joining P2 | JP2, TCRGJP2 |
| TRGV2 | T cell receptor gamma variable 2 | MGC42817, TCRGV2, VIS2 |
| TRGV3 | T cell receptor gamma variable 3 | TCRGV3, V1S3 |
| TRGV4 | T cell receptor gamma variable 4 | TCRGV4, V1S4 |
| TRGV5 | T cell receptor gamma variable 5 | TCRGV5, V1S5 |
| TRGV8 | T cell receptor gamma variable 8 | TCRGV8, V1S8 |
| TRGV9 | T cell receptor gamma variable 9 | MGC47828, TCRGV9, V2 |
| VAV1 | vav 1 guanine nucleotide exchange factor | VAV |
| VAV2 | vav 2 guanine nucleotide exchange factor | - |
| VAV3 | vav 3 guanine nucleotide exchange factor | FLJ40431 |
| ZAP70 | zeta-chain (TCR) associated protein kinase 70kDa | FLJ17670, FLJ17679, SRK, STD, TZK, ZAP-70 |
TGFbeta
In the immune system, Tumour Growth Factor beta (TGFbeta) signaling and its downstream effector molecules, the Smad proteins, regulate the adaptive immune response through effects on numerous immune cell types including T cells and B cells. It also impacts the development and function of innate immune cells including NK cells, macrophages, dendritic cells, and granulocytes.
| Symbol | Name | Synonyms |
|---|---|---|
| ACVR1B | activin A receptor, type IB | ACTRIB, ACVRLK4, ALK4, SKR2 |
| ACVR1C | activin A receptor, type IC | ACVRLK7, ALK7 |
| ACVR2A | activin A receptor, type IIA | ACTRII, ACVR2 |
| ACVR2B | activin A receptor, type IIB | ACTRIIB, ActR-IIB, MGC116908 |
| ACVRL1 | activin A receptor type II-like 1 | ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I |
| AMHR2 | anti-Mullerian hormone receptor, type II | AMHR, MISR2, MISRII |
| BMP1 | bone morphogenetic protein 1 | FLJ44432, PCOLC, PCP, TLD, pCP-2 |
| BMP10 | bone morphogenetic protein 10 | MGC126783 |
| BMP15 | bone morphogenetic protein 15 | GDF9B, ODG2, POF4 |
| BMP2 | bone morphogenetic protein 2 | BMP2A |
| BMP3 | bone morphogenetic protein 3 | BMP-3A |
| BMP4 | bone morphogenetic protein 4 | BMP2B, BMP2B1, MCOPS6, OFC11, ZYME |
| BMP5 | bone morphogenetic protein 5 | MGC34244 |
| BMP6 | bone morphogenetic protein 6 | VGR, VGR1 |
| BMP7 | bone morphogenetic protein 7 | OP-1 |
| BMP8A | bone morphogenetic protein 8a | FLJ14351, FLJ45264 |
| BMP8B | bone morphogenetic protein 8b | BMP8, MGC131757, OP2 |
| BMPR1A | bone morphogenetic protein receptor, type IA | 10q23del, ACVRLK3, ALK3, CD292, SKR5 |
| BMPR1B | bone morphogenetic protein receptor, type IB | ALK-6, ALK6, CDw293 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | BMPR-II, BMPR3, BMR2, BRK-3, FLJ41585, FLJ76945, PPH1, T-ALK |
| GDF1 | growth differentiation factor 1 | - |
| GDF10 | growth differentiation factor 10 | BMP-3b, BMP3B |
| GDF11 | growth differentiation factor 11 | BMP-11, BMP11 |
| GDF15 | growth differentiation factor 15 | GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB |
| GDF2 | growth differentiation factor 2 | BMP-9, BMP9 |
| GDF3 | growth differentiation factor 3 | - |
| GDF5 | growth differentiation factor 5 | BMP14, CDMP1, LAP4, OS5, SYNS2 |
| GDF6 | growth differentiation factor 6 | BMP13, CDMP2, KFS, KFSL, MGC158100, MGC158101, SGM1 |
| GDF7 | growth differentiation factor 7 | BMP12 |
| GDF9 | growth differentiation factor 9 | - |
| GDNF | glial cell derived neurotrophic factor | ATF1, ATF2, HFB1-GDNF |
| INHA | inhibin, alpha | - |
| INHBA | inhibin, beta A | EDF, FRP |
| INHBB | inhibin, beta B | MGC157939 |
| INHBC | inhibin, beta C | IHBC |
| INHBE | inhibin, beta E | MGC4638 |
| LEFTY1 | left-right determination factor 1 | LEFTB, LEFTYB |
| LEFTY2 | left-right determination factor 2 | EBAF, LEFTA, LEFTYA, MGC46222, TGFB4 |
| NODAL | nodal homolog (mouse) | MGC138230 |
| TGFB1 | transforming growth factor, beta 1 | CED, DPD1, TGFB, TGFbeta |
| TGFB2 | transforming growth factor, beta 2 | MGC116892, TGF-beta2 |
| TGFB3 | transforming growth factor, beta 3 | ARVD, FLJ16571, TGF-beta3 |
| TGFBR1 | transforming growth factor, beta receptor 1 | AAT5, ACVRLK4, ALK-5, ALK5, LDS1A, LDS2A, SKR4, TGFR-1 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | AAT3, FAA3, LDS1B, LDS2B, MFS2, RIIC, TAAD2, TGFR-2, TGFbeta-RII |
| TGFBR3 | transforming growth factor, beta receptor III | BGCAN, betaglycan |
TLR
The toll like receptors (TLR) play a key role in the innate immune system. They are found on dendritic cells and macrophages and sense conserved microbial molecules during an infection. When TLRs sense a microbial pathogen, they trigger signalling pathways that lead to the activation of an immune response.
| Symbol | Name | Synonyms |
|---|---|---|
| TLR1 | toll-like receptor 1 | TIL, CD281, rsc786, TIL. LPRS5 |
| TLR10 | toll-like receptor 10 | CD290 |
| TLR12P | toll like receptor 12, pseudogene(TLR12P) | - |
| TLR2 | toll-like receptor 2 | TIL4, CD282 |
| TLR3 | toll-like receptor 3 | CD283, IIAE2 |
| TLR4 | toll-like receptor 4 | TOLL, CD284, TLR-4, ARMD10 |
| TLR5 | toll-like receptor 5 | SLE1, TIL3, SLEB1, MELIOS |
| TLR6 | toll-like receptor 6 | CD286 |
| TLR7 | toll-like receptor 7 | TLR7-like |
| TLR8 | toll-like receptor 8 | CD288 |
| TLR9 | toll-like receptor 9 | CD289 |
TNF
The tumor necrosis factor (TNF) family of proteins are predominantly expressed by immune cells and help to regulate the immune response and inflammation. They act as cytokines when cleaved from the cell membrane and can also function as signaling proteins involved in proliferation, cell differentiation, and apoptosis.
| Symbol | Name | Synonyms |
|---|---|---|
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9 |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain | CD263, DCR1, LIT, MGC149501, MGC149502, TRAILR3, TRID |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | CD264, DCR2, TRAILR4, TRUNDD |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator | CD265, FEO, LOH18CR1, ODFR, OFE, OPTB7, OSTS, PDB2, RANK, TRANCER |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | MGC29565, OCIF, OPG, TR1 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | CD266, FN14, TWEAKR |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B | CD267, CVID, FLJ39942, MGC133214, MGC39952, TACI, TNFRSF14B |
| TNFRSF13C | tumor necrosis factor receptor superfamily, member 13C | BAFF-R, BAFFR, CD268, MGC138235 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) | ATAR, HVEA, HVEM, LIGHTR, TR2 |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 | BCM, BCMA, CD269 |
| TNFRSF18 | tumor necrosis factor receptor superfamily, member 18 | AITR, GITR, GITR-D |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | TAJ, TAJ-alpha, TRADE, TROY |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | CD120a, FPF, MGC19588, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR55, TNFR60, p55, p55-R, p60 |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | BM-018, DR6, MGC31965 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 | APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR |
| TNFRSF4 | tumor necrosis factor receptor superfamily, member 4 | ACT35, CD134, OX40, TXGP1L |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | DCR3, DJ583P15.1.1, M68, TR6 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 | CD30, D1S166E, Ki-1 |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 4-1BB, CD137, CDw137, ILA, MGC2172 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | APO2L, Apo-2L, CD253, TL2, TRAIL |
| TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 | CD254, ODF, OPGL, OPTB2, RANKL, TRANCE, hRANKL2, sOdf |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 | APO3L, DR3LG, MGC129581, MGC20669, TWEAK |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 | APRIL, CD256, TALL2, TRDL-1, UNQ383/PRO715, ligand |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | BAFF, BLYS, CD257, DTL, TALL-1, TALL1, THANK, TNFSF20, ZTNF4 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | CD258, HVEML, LIGHT, LTg, TR2 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 | MGC129934, MGC129935, TL1, TL1A, VEGI, VEGI192A |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 | AITRL, GITRL, MGC138237, TL6, hGITRL |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | CD134L, CD252, GP34, OX-40L, OX4OL, TXGP1 |
| TNFSF8 | tumor necrosis factor (ligand) superfamily, member 8 | CD153, CD30L, CD30LG, MGC138144 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | 4-1BB-L, CD137L |
Additional Resources
Plasmid Kits and Collections
- Human Kinase ORF Kit: 558 distinct human kinases and kinase-related protein Open Reading Frames (ORFs) in pDONR-223 Gateway® Entry vectors from the labs of William Hahn and David Root.
- Multiple Lentiviral Expression (MuLE) System Kit : A modular and flexible system that can be used to construct complex lentiviruses for modification of mammalian cells with a single viral infection from the lab of Ian Frew.
- MXS Chaining Kit: From the lab of Pierre Neveu, the MXS-chaining system allows efficient assembly of constructs that are optimized for synthetic biology applications in mammalian systems. The MXS-chaining kit includes chaining vectors with multiple cloning sites and standardized building blocks: 14 different fluorescent proteins, 10 mammalian promoters and enhancers, 3 polyA signals as well as selection cassettes and tools for inducible gene expression.
- Myristoylated Kinase Kit: Consists of 190 human kinases and kinase-related open reading frames (ORFs) cloned into a retroviral vector which adds a myristoylation sequence and flag-epitope tag to each ORF from the labs of William Hahn and Jean Zhao.
- Phagemid Synuclein VHH Immune Library: This library from Anne Messer and the Michael J Fox Foundation is a synuclein phagemid VHH phage display library used to screen for antibodies that bind to the NAC domain of alpha-syn(A53T).
- Target Accelerator Genetic Pathway Reference Set: From Jesse Boehm, William Hahn, Matthew Meyerson, and David Root, this kit consists of 182 wild-type and 19 well-characterized mutant ORFs that represent over 25 cellular signaling pathways and processes.
Addgene Blogs
- Adeno Associated Virus (AAV) for Cell and Gene Therapy
- Cancer and the Immune System: Deciphering the Relationship
- Cancer, Inflammation and Immunity - Harnessing the Body’s Defenses to Fight Cancer
- Plasmids 101: Monitoring Cell Mobility Using Fluorescent Proteins
- The Challenges of Cell Culture
External Resouces
- Immport: Bhattacharya S, Dunn P, Thomas CG, Smith B, Schaefer H, Chen J, Hu Z, Zalocusky KA, Shankar RD, Shen-Orr SS, Thomson E, Wiser J, Butte AJ. 2018. ImmPort, toward repurposing of open access immunological assay data for translational and clinical research. Sci Data. Feb 27;5:180015. doi: 10.1038/sdata.2018.15. PMID 29485622
Do you have suggestions for other plasmids that should be added to this list?
Fill out our Suggest a Plasmid form or e-mail [email protected] to help us improve this resource!