Targeted genetic dependency screen facilitates identification of actionable mutations in FGFR4, MAP3K9, and PAK5 in lung cancer.
Fawdar S, Trotter EW, Li Y, Stephenson NL, Hanke F, Marusiak AA, Edwards ZC, Ientile S, Waszkowycz B, Miller CJ, Brognard J
Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12426-31. doi: 10.1073/pnas.1305207110. Epub 2013 Jul 8.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 60531 | pENTR221-FGFR4 | Entry vector for human FGFR4 |
| 60532 | pDONR223 PAK5 | Donor vector for human Pak5 |
| 60533 | pDONR223 PAK5 P50L | Donor vector for human Pak5 P50L mutant |
| 60534 | pDONR223 PAK5 P76T | Donor vector for human Pak5 P76T mutant |
| 60535 | pDONR223 PAK5 S312C | Donor vector for human Pak5 S312C mutant |
| 60536 | pDONR223 PAK5 V463L | Donor vector for human Pak5 V463L mutant |
| 60537 | pDONR223 PAK5 T538N | Donor vector for human Pak5 T538N mutant |
| 60538 | pDONR223 PAK5 S573N | Donor vector for human Pak5 S573N mutant |
| 60539 | pDONR223 PAK5 V593I | Donor vector for human Pak5 V593I mutant |
| 60540 | pDONR221 MLK1 | Donor vector for human MLK1 |
| 60541 | pDONR221 MLK1 E179K | Donor vector for human MLK1 E179K mutant |
| 60542 | pDONR221 MLK1 D294A | Donor vector for human MLK1 D294A mutant |