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MiR-199a-3p decreases esophageal cancer cell proliferation by targeting p21 activated kinase 4.

Phatak P, Burrows WM, Chesnick IE, Tulapurkar ME, Rao JN, Turner DJ, Hamburger AW, Wang JY, Donahue JM
Oncotarget. 2018 Jun 19;9(47):28391-28407. doi: 10.18632/oncotarget.25375. eCollection 2018 Jun 19. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
113088PAK4-FL-3'UTRLuciferase reporter containing PAK4- FL-3'UTR
113090PAK4-3'UTR-BS1Luciferase reporter containing PAK4 3' UTR with the first predicted MiR-199a-3p binding site
113091PAK4-3'UTR-BS2Luciferase reporter containing PAK4 3' UTR with the second predicted MiR-199a-3p binding
113093PAK4-FL-3'UTR-MT2Luciferase reporter containing PAK4-FL- 3' UTR with the second predicted MiR-199a-3p binding site mutated
113094PAK4-FL-3'UTR-MT-bothLuciferase reporter containing PAK4-FL- 3' UTR with both the predicted MiR-199a-3p binding sites mutated

Antibodies from Article