pHR-SFFV-KRAB-dCas9-P2A-mCherry Citations (56)
Originally described in: Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation.Gilbert LA, Horlbeck MA, Adamson B, Villalta JE, Chen Y, Whitehead EH, Guimaraes C, Panning B, Ploegh HL, Bassik MC, Qi LS, Kampmann M, Weissman JS Cell. 2014 Oct 23;159(3):647-61. doi: 10.1016/j.cell.2014.09.029. Epub 2014 Oct 9. PubMed Journal
Articles Citing pHR-SFFV-KRAB-dCas9-P2A-mCherry
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| Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers. Zhang X, Choi PS, Francis JM, Imielinski M, Watanabe H, Cherniack AD, Meyerson M. Nat Genet. 2016 Feb;48(2):176-82. doi: 10.1038/ng.3470. Epub 2015 Dec 14. PubMed |
| Optimizing sgRNA position markedly improves the efficiency of CRISPR/dCas9-mediated transcriptional repression. Radzisheuskaya A, Shlyueva D, Muller I, Helin K. Nucleic Acids Res. 2016 Oct 14;44(18):e141. Epub 2016 Jun 28. PubMed |
Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR-Cas9 library.
Zhu S, Li W, Liu J, Chen CH, Liao Q, Xu P, Xu H, Xiao T, Cao Z, Peng J, Yuan P, Brown M, Liu XS, Wei W.
Nat Biotechnol. 2016 Dec;34(12):1279-1286. doi: 10.1038/nbt.3715. Epub 2016 Oct 31.
PubMed
Associated Plasmids |
| Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells. Elia I, Broekaert D, Christen S, Boon R, Radaelli E, Orth MF, Verfaillie C, Grunewald TGP, Fendt SM. Nat Commun. 2017 May 11;8:15267. doi: 10.1038/ncomms15267. PubMed |
MELK is not necessary for the proliferation of basal-like breast cancer cells.
Huang HT, Seo HS, Zhang T, Wang Y, Jiang B, Li Q, Buckley DL, Nabet B, Roberts JM, Paulk J, Dastjerdi S, Winter GE, McLauchlan H, Moran J, Bradner JE, Eck MJ, Dhe-Paganon S, Zhao JJ, Gray NS.
Elife. 2017 Sep 19;6. pii: e26693. doi: 10.7554/eLife.26693.
PubMed
Associated Plasmids |
| Allele-specific long-distance regulation dictates IL-32 isoform switching and mediates susceptibility to HIV-1. Palstra RJ, de Crignis E, Roling MD, van Staveren T, Kan TW, van Ijcken W, Mueller YM, Katsikis PD, Mahmoudi T. Sci Adv. 2018 Feb 21;4(2):e1701729. doi: 10.1126/sciadv.1701729. eCollection 2018 Feb. PubMed |
NuRD and CAF-1-mediated silencing of the D4Z4 array is modulated by DUX4-induced MBD3L proteins.
Campbell AE, Shadle SC, Jagannathan S, Lim JW, Resnick R, Tawil R, van der Maarel SM, Tapscott SJ.
Elife. 2018 Mar 13;7. pii: 31023. doi: 10.7554/eLife.31023.
PubMed
Associated Plasmids |
| Expression of a Constitutively Active Human Insulin Receptor in Hippocampal Neurons Does Not Alter VGCC Currents. Frazier HN, Anderson KL, Maimaiti S, Ghoweri AO, Kraner SD, Popa GJ, Hampton KK, Mendenhall MD, Norris CM, Craven RJ, Thibault O. Neurochem Res. 2019 Jan;44(1):269-280. doi: 10.1007/s11064-018-2510-2. Epub 2018 Mar 23. PubMed |
| NF-kappaB-Dependent Lymphoid Enhancer Co-option Promotes Renal Carcinoma Metastasis. Rodrigues P, Patel SA, Harewood L, Olan I, Vojtasova E, Syafruddin SE, Zaini MN, Richardson EK, Burge J, Warren AY, Stewart GD, Saeb-Parsy K, Samarajiwa SA, Vanharanta S. Cancer Discov. 2018 Jul;8(7):850-865. doi: 10.1158/2159-8290.CD-17-1211. Epub 2018 Jun 6. PubMed |
| Epigenome editing of microsatellite repeats defines tumor-specific enhancer functions and dependencies. Boulay G, Volorio A, Iyer S, Broye LC, Stamenkovic I, Riggi N, Rivera MN. Genes Dev. 2018 Aug 1;32(15-16):1008-1019. doi: 10.1101/gad.315192.118. Epub 2018 Jul 24. PubMed |
Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing.
Haldeman JM, Conway AE, Arlotto ME, Slentz DH, Muoio DM, Becker TC, Newgard CB.
Nucleic Acids Res. 2018 Dec 27. pii: 5264291. doi: 10.1093/nar/gky1286.
PubMed
Associated Plasmids |
| The splicing factor RBM25 controls MYC activity in acute myeloid leukemia. Ge Y, Schuster MB, Pundhir S, Rapin N, Bagger FO, Sidiropoulos N, Hashem N, Porse BT. Nat Commun. 2019 Jan 11;10(1):172. doi: 10.1038/s41467-018-08076-y. PubMed |
| A KLF6-driven transcriptional network links lipid homeostasis and tumour growth in renal carcinoma. Syafruddin SE, Rodrigues P, Vojtasova E, Patel SA, Zaini MN, Burge J, Warren AY, Stewart GD, Eisen T, Bihary D, Samarajiwa SA, Vanharanta S. Nat Commun. 2019 Mar 11;10(1):1152. doi: 10.1038/s41467-019-09116-x. PubMed |
| SABER amplifies FISH: enhanced multiplexed imaging of RNA and DNA in cells and tissues. Kishi JY, Lapan SW, Beliveau BJ, West ER, Zhu A, Sasaki HM, Saka SK, Wang Y, Cepko CL, Yin P. Nat Methods. 2019 Jun;16(6):533-544. doi: 10.1038/s41592-019-0404-0. Epub 2019 May 20. PubMed |
| Transcriptional States and Chromatin Accessibility Underlying Human Erythropoiesis. Ludwig LS, Lareau CA, Bao EL, Nandakumar SK, Muus C, Ulirsch JC, Chowdhary K, Buenrostro JD, Mohandas N, An X, Aryee MJ, Regev A, Sankaran VG. Cell Rep. 2019 Jun 11;27(11):3228-3240.e7. doi: 10.1016/j.celrep.2019.05.046. PubMed |
| SOX4 regulates invasion of bladder cancer cells via repression of WNT5a. Moran JD, Kim HH, Li Z, Moreno CS. Int J Oncol. 2019 Aug;55(2):359-370. doi: 10.3892/ijo.2019.4832. Epub 2019 Jun 26. PubMed |
| Integrated analyses of murine breast cancer models reveal critical parallels with human disease. Rennhack JP, To B, Swiatnicki M, Dulak C, Ogrodzinski MP, Zhang Y, Li C, Bylett E, Ross C, Szczepanek K, Hanrahan W, Jayatissa M, Lunt SY, Hunter K, Andrechek ER. Nat Commun. 2019 Jul 22;10(1):3261. doi: 10.1038/s41467-019-11236-3. PubMed |
| Molecular determinants for enzalutamide-induced transcription in prostate cancer. Yuan F, Hankey W, Wu D, Wang H, Somarelli J, Armstrong AJ, Huang J, Chen Z, Wang Q. Nucleic Acids Res. 2019 Nov 4;47(19):10104-10114. doi: 10.1093/nar/gkz790. PubMed |
| Genomic and epigenomic mapping of leptin-responsive neuronal populations involved in body weight regulation. Inoue F, Eckalbar WL, Wang Y, Murphy KK, Matharu N, Vaisse C, Ahituv N. Nat Metab. 2019 Apr;1(4):475-484. doi: 10.1038/s42255-019-0051-x. Epub 2019 Apr 8. PubMed |
| PRMT5 methylome profiling uncovers a direct link to splicing regulation in acute myeloid leukemia. Radzisheuskaya A, Shliaha PV, Grinev V, Lorenzini E, Kovalchuk S, Shlyueva D, Gorshkov V, Hendrickson RC, Jensen ON, Helin K. Nat Struct Mol Biol. 2019 Nov;26(11):999-1012. doi: 10.1038/s41594-019-0313-z. Epub 2019 Oct 14. PubMed |
| Identification and Massively Parallel Characterization of Regulatory Elements Driving Neural Induction. Inoue F, Kreimer A, Ashuach T, Ahituv N, Yosef N. Cell Stem Cell. 2019 Nov 7;25(5):713-727.e10. doi: 10.1016/j.stem.2019.09.010. Epub 2019 Oct 17. PubMed |
| A genome-wide long noncoding RNA CRISPRi screen identifies PRANCR as a novel regulator of epidermal homeostasis. Cai P, Otten ABC, Cheng B, Ishii MA, Zhang W, Huang B, Qu K, Sun BK. Genome Res. 2020 Jan;30(1):22-34. doi: 10.1101/gr.251561.119. Epub 2019 Dec 4. PubMed |
| Rainbow Kaposi's Sarcoma-Associated Herpesvirus Revealed Heterogenic Replication with Dynamic Gene Expression. Nakajima KI, Guevara-Plunkett S, Chuang F, Wang KH, Lyu Y, Kumar A, Luxardi G, Izumiya C, Soulika A, Campbell M, Izumiya Y. J Virol. 2020 Mar 31;94(8). pii: JVI.01565-19. doi: 10.1128/JVI.01565-19. Print 2020 Mar 31. PubMed |
| Cancer Cell-Derived Matrisome Proteins Promote Metastasis in Pancreatic Ductal Adenocarcinoma. Tian C, Ohlund D, Rickelt S, Lidstrom T, Huang Y, Hao L, Zhao RT, Franklin O, Bhatia SN, Tuveson DA, Hynes RO. Cancer Res. 2020 Apr 1;80(7):1461-1474. doi: 10.1158/0008-5472.CAN-19-2578. Epub 2020 Feb 6. PubMed |
| A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells. Guo L, Li J, Zeng H, Guzman AG, Li T, Lee M, Zhou Y, Goodell MA, Stephan C, Davies PJA, Dawson MA, Sun D, Huang Y. Nat Commun. 2020 Feb 6;11(1):740. doi: 10.1038/s41467-020-14604-6. PubMed |
| FAM13A affects body fat distribution and adipocyte function. Fathzadeh M, Li J, Rao A, Cook N, Chennamsetty I, Seldin M, Zhou X, Sangwung P, Gloudemans MJ, Keller M, Attie A, Yang J, Wabitsch M, Carcamo-Orive I, Tada Y, Lusis AJ, Shin MK, Molony CM, McLaughlin T, Reaven G, Montgomery SB, Reilly D, Quertermous T, Ingelsson E, Knowles JW. Nat Commun. 2020 Mar 19;11(1):1465. doi: 10.1038/s41467-020-15291-z. PubMed |
| Inference of single-cell phylogenies from lineage tracing data using Cassiopeia. Jones MG, Khodaverdian A, Quinn JJ, Chan MM, Hussmann JA, Wang R, Xu C, Weissman JS, Yosef N. Genome Biol. 2020 Apr 14;21(1):92. doi: 10.1186/s13059-020-02000-8. PubMed |
| Tumor Interferon Signaling Is Regulated by a lncRNA INCR1 Transcribed from the PD-L1 Locus. Mineo M, Lyons SM, Zdioruk M, von Spreckelsen N, Ferrer-Luna R, Ito H, Alayo QA, Kharel P, Giantini Larsen A, Fan WY, Auduong S, Grauwet K, Passaro C, Khalsa JK, Shah K, Reardon DA, Ligon KL, Beroukhim R, Nakashima H, Ivanov P, Anderson PJ, Lawler SE, Chiocca EA. Mol Cell. 2020 Jun 18;78(6):1207-1223.e8. doi: 10.1016/j.molcel.2020.05.015. Epub 2020 Jun 5. PubMed |
| Endogenous retroviruses are a source of enhancers with oncogenic potential in acute myeloid leukaemia. Deniz O, Ahmed M, Todd CD, Rio-Machin A, Dawson MA, Branco MR. Nat Commun. 2020 Jul 14;11(1):3506. doi: 10.1038/s41467-020-17206-4. PubMed |
| Tuning the Expression of Long Noncoding RNA Loci with CRISPR Interference. Stojic L. Methods Mol Biol. 2020;2161:1-16. doi: 10.1007/978-1-0716-0680-3_1. PubMed |
| Elevating Insulin Signaling Using a Constitutively Active Insulin Receptor Increases Glucose Metabolism and Expression of GLUT3 in Hippocampal Neurons. Frazier HN, Ghoweri AO, Anderson KL, Lin RL, Popa GJ, Mendenhall MD, Reagan LP, Craven RJ, Thibault O. Front Neurosci. 2020 Jul 7;14:668. doi: 10.3389/fnins.2020.00668. eCollection 2020. PubMed |
| CRISPRi-mediated depletion of Spt4 and Spt5 reveals a role for DSIF in the control of HIV latency. Krasnopolsky S, Novikov A, Kuzmina A, Taube R. Biochim Biophys Acta Gene Regul Mech. 2021 Jan;1864(1):194656. doi: 10.1016/j.bbagrm.2020.194656. Epub 2020 Dec 15. PubMed |
| SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression. Hou G, Harley ITW, Lu X, Zhou T, Xu N, Yao C, Qin Y, Ouyang Y, Ma J, Zhu X, Yu X, Xu H, Dai D, Ding H, Yin Z, Ye Z, Deng J, Zhou M, Tang Y, Namjou B, Guo Y, Weirauch MT, Kottyan LC, Harley JB, Shen N. Nat Commun. 2021 Jan 8;12(1):135. doi: 10.1038/s41467-020-20460-1. PubMed |
| Proteome dynamics at broken replication forks reveal a distinct ATM-directed repair response suppressing DNA double-strand break ubiquitination. Nakamura K, Kustatscher G, Alabert C, Hodl M, Forne I, Volker-Albert M, Satpathy S, Beyer TE, Mailand N, Choudhary C, Imhof A, Rappsilber J, Groth A. Mol Cell. 2021 Mar 4;81(5):1084-1099.e6. doi: 10.1016/j.molcel.2020.12.025. Epub 2021 Jan 14. PubMed |
| Epidermal progenitors suppress GRHL3-mediated differentiation through intronic polyadenylation promoted by CPSF-HNRNPA3 collaboration. Chen X, Lloyd SM, Kweon J, Gamalong GM, Bao X. Nat Commun. 2021 Jan 19;12(1):448. doi: 10.1038/s41467-020-20674-3. PubMed |
| TRIM26 is a critical host factor for HCV replication and contributes to host tropism. Liang Y, Zhang G, Li Q, Han L, Hu X, Guo Y, Tao W, Zhao X, Guo M, Gan T, Tong Y, Xu Y, Zhou Z, Ding Q, Wei W, Zhong J. Sci Adv. 2021 Jan 8;7(2). pii: 7/2/eabd9732. doi: 10.1126/sciadv.abd9732. Print 2021 Jan. PubMed |
| [Levels of sgRNA as a Major Factor Affecting CRISPRi Knockdown Efficiency in K562 Cells]. Wang Y, Xie Y, Dong ZC, Jiang XJ, Gong P, Lu J, Wan F. Mol Biol (Mosk). 2021 Jan-Feb;55(1):86-95. doi: 10.31857/S0026898421010146. PubMed |
| Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis. Radzisheuskaya A, Shliaha PV, Grinev VV, Shlyueva D, Damhofer H, Koche R, Gorshkov V, Kovalchuk S, Zhan Y, Rodriguez KL, Johnstone AL, Keogh MC, Hendrickson RC, Jensen ON, Helin K. Mol Cell. 2021 Apr 15;81(8):1749-1765.e8. doi: 10.1016/j.molcel.2021.02.012. Epub 2021 Mar 2. PubMed |
| Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element. Baxter JS, Johnson N, Tomczyk K, Gillespie A, Maguire S, Brough R, Fachal L, Michailidou K, Bolla MK, Wang Q, Dennis J, Ahearn TU, Andrulis IL, Anton-Culver H, Antonenkova NN, Arndt V, Aronson KJ, Augustinsson A, Becher H, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Bogdanova NV, Bojesen SE, Brenner H, Brucker SY, Cai Q, Campa D, Canzian F, Castelao JE, Chan TL, Chang-Claude J, Chanock SJ, Chenevix-Trench G, Choi JY, Clarke CL, Colonna S, Conroy DM, Couch FJ, Cox A, Cross SS, Czene K, Daly MB, Devilee P, Dork T, Dossus L, Dwek M, Eccles DM, Ekici AB, Eliassen AH, Engel C, Fasching PA, Figueroa J, Flyger H, Gago-Dominguez M, Gao C, Garcia-Closas M, Garcia-Saenz JA, Ghoussaini M, Giles GG, Goldberg MS, Gonzalez-Neira A, Guenel P, Gundert M, Haeberle L, Hahnen E, Haiman CA, Hall P, Hamann U, Hartman M, Hatse S, Hauke J, Hollestelle A, Hoppe R, Hopper JL, Hou MF, Ito H, Iwasaki M, Jager A, Jakubowska A, Janni W, John EM, Joseph V, Jung A, Kaaks R, Kang D, Keeman R, Khusnutdinova E, Kim SW, Kosma VM, Kraft P, Kristensen VN, Kubelka-Sabit K, Kurian AW, Kwong A, Lacey JV, Lambrechts D, Larson NL, Larsson SC, Le Marchand L, Lejbkowicz F, Li J, Long J, Lophatananon A, Lubinski J, Mannermaa A, Manoochehri M, Manoukian S, Margolin S, Matsuo K, Mavroudis D, Mayes R, Menon U, Milne RL, Mohd Taib NA, Muir K, Muranen TA, Murphy RA, Nevanlinna H, O'Brien KM, Offit K, Olson JE, Olsson H, Park SK, Park-Simon TW, Patel AV, Peterlongo P, Peto J, Plaseska-Karanfilska D, Presneau N, Pylkas K, Rack B, Rennert G, Romero A, Ruebner M, Rudiger T, Saloustros E, Sandler DP, Sawyer EJ, Schmidt MK, Schmutzler RK, Schneeweiss A, Schoemaker MJ, Shah M, Shen CY, Shu XO, Simard J, Southey MC, Stone J, Surowy H, Swerdlow AJ, Tamimi RM, Tapper WJ, Taylor JA, Teo SH, Teras LR, Terry MB, Toland AE, Tomlinson I, Truong T, Tseng CC, Untch M, Vachon CM, van den Ouweland AMW, Wang SS, Weinberg CR, Wendt C, Winham SJ, Winqvist R, Wolk A, Wu AH, Yamaji T, Zheng W, Ziogas A, Pharoah PDP, Dunning AM, Easton DF, Pettitt SJ, Lord CJ, Haider S, Orr N, Fletcher O. Am J Hum Genet. 2021 Jul 1;108(7):1190-1203. doi: 10.1016/j.ajhg.2021.05.013. Epub 2021 Jun 18. PubMed |
| Dual-Specificity Phosphatase 9 Regulates Cellular Proliferation and Predicts Recurrence After Surgery in Hepatocellular Carcinoma. Chen K, Gorgen A, Ding A, Du L, Jiang K, Ding Y, Sapisochin G, Ghanekar A. Hepatol Commun. 2021 Mar 11;5(7):1310-1328. doi: 10.1002/hep4.1701. eCollection 2021 Jul. PubMed |
| Using CRISPR Interference as a Therapeutic Approach to Treat TGFbeta2-Induced Ocular Hypertension and Glaucoma. Rayana NP, Sugali CK, Dai J, Peng M, Liu S, Zhang Y, Wan J, Mao W. Invest Ophthalmol Vis Sci. 2021 Sep 2;62(12):7. doi: 10.1167/iovs.62.12.7. PubMed |
Bacterial Retrons Enable Precise Gene Editing in Human Cells.
Zhao B, Chen SA, Lee J, Fraser HB.
CRISPR J. 2022 Jan 24. doi: 10.1089/crispr.2021.0065.
PubMed
Associated Plasmids |
| Targeting S100A9-ALDH1A1-Retinoic Acid Signaling to Suppress Brain Relapse in EGFR-Mutant Lung Cancer. Biswas AK, Han S, Tai Y, Ma W, Coker C, Quinn SA, Shakri AR, Zhong TJ, Scholze H, Lagos GG, Mela A, Manova-Todorova K, de Stanchina E, Ferrando AA, Mendelsohn C, Canoll P, Yu HA, Paik PK, Saqi A, Shu CA, Kris MG, Massague J, Acharyya S. Cancer Discov. 2022 Apr 1;12(4):1002-1021. doi: 10.1158/2159-8290.CD-21-0910. PubMed |
| Screening of ETO2-GLIS2-induced Super Enhancers identifies targetable cooperative dependencies in acute megakaryoblastic leukemia. Benbarche S, Lopez CK, Salataj E, Aid Z, Thirant C, Laiguillon MC, Lecourt S, Belloucif Y, Vaganay C, Antonini M, Hu J, da Silva Babinet A, Ndiaye-Lobry D, Pardieu B, Petit A, Puissant A, Chaumeil J, Mercher T, Lobry C. Sci Adv. 2022 Feb 11;8(6):eabg9455. doi: 10.1126/sciadv.abg9455. Epub 2022 Feb 9. PubMed |
| Identification of an endoplasmic reticulum proteostasis modulator that enhances insulin production in pancreatic beta cells. Miyake M, Sobajima M, Kurahashi K, Shigenaga A, Denda M, Otaka A, Saio T, Sakane N, Kosako H, Oyadomari S. Cell Chem Biol. 2022 Jun 16;29(6):996-1009.e9. doi: 10.1016/j.chembiol.2022.01.002. Epub 2022 Feb 9. PubMed |
| Lupus enhancer risk variant causes dysregulation of IRF8 through cooperative lncRNA and DNA methylation machinery. Zhou T, Zhu X, Ye Z, Wang YF, Yao C, Xu N, Zhou M, Ma J, Qin Y, Shen Y, Tang Y, Yin Z, Xu H, Zhang Y, Zang X, Ding H, Yang W, Guo Y, Harley JB, Namjou B, Kaufman KM, Kottyan LC, Weirauch MT, Hou G, Shen N. Nat Commun. 2022 Apr 6;13(1):1855. doi: 10.1038/s41467-022-29514-y. PubMed |
| T cell stimulation remodels the latently HIV-1 infected cell population by differential activation of proviral chromatin. Lindqvist B, Jutte BB, Love L, Assi W, Roux J, Sonnerborg A, Tezil T, Verdin E, Svensson JP. PLoS Pathog. 2022 Jun 6;18(6):e1010555. doi: 10.1371/journal.ppat.1010555. eCollection 2022 Jun. PubMed |
| Identification of a distal enhancer that determines the expression pattern of acute phase marker C-reactive protein. Wang MY, Zhang CM, Zhou HH, Ge ZB, Su CC, Lou ZH, Zhang XY, Xu TT, Li SY, Zhu L, Zhou YL, Wu Y, Ji SR. J Biol Chem. 2022 Aug;298(8):102160. doi: 10.1016/j.jbc.2022.102160. Epub 2022 Jun 17. PubMed |
| Integrative Functional Genomics Identifies Systemic Lupus Erythematosus Causal Genetic Variant in the IRF5 Risk Locus. Hou G, Zhou T, Xu N, Yin Z, Zhu X, Zhang Y, Cui Y, Ma J, Tang Y, Cheng Z, Shen Y, Chen Y, Zou LH, Wang YF, Yin Z, Guo Y, Ding H, Ye Z, Shen N. Arthritis Rheumatol. 2023 Apr;75(4):574-585. doi: 10.1002/art.42390. Epub 2023 Feb 8. PubMed |
| SGOL1-AS1 enhances cell survival in acute myeloid leukemia by maintaining pro-inflammatory signaling. Selkirk E, Patel R, Hoyle A, Lie-A-Ling M, Smith D, Swift J, Lacaud G. Heliyon. 2022 Nov 5;8(11):e11362. doi: 10.1016/j.heliyon.2022.e11362. eCollection 2022 Nov. PubMed |
| Production of CRISPRi-engineered primary human mammary epithelial cells with baboon envelope pseudotyped lentiviral vectors. Pastor S, Wicinski J, Charafe-Jauffret E, Verhoeyen E, Guittard G, Ginestier C. STAR Protoc. 2023 Jan 19;4(1):102055. doi: 10.1016/j.xpro.2023.102055. PubMed |
| Multiplexed long-read plasmid validation and analysis using OnRamp. Mumm C, Drexel ML, McDonald TL, Diehl AG, Switzenberg JA, Boyle AP. Genome Res. 2023 May;33(5):741-749. doi: 10.1101/gr.277369.122. Epub 2023 May 8. PubMed |
| Selective Enhancer Dependencies in MYC -Intact and MYC -Rearranged Germinal Center B-cell Diffuse Large B-cell Lymphoma. Iyer AR, Gurumurthy A, Kodgule R, Aguilar AR, Saari T, Ramzan A, Rausch D, Gupta J, Hall CN, Runge JS, Weiss M, Rahmat M, Anyoha R, Fulco CP, Ghobrial IM, Engreitz J, Cieslik MP, Ryan RJH. bioRxiv. 2023 May 3:2023.05.02.538892. doi: 10.1101/2023.05.02.538892. Preprint. PubMed |
| LncRNA INHEG promotes glioma stem cell maintenance and tumorigenicity through regulating rRNA 2'-O-methylation. Liu L, Liu Z, Liu Q, Wu W, Lin P, Liu X, Zhang Y, Wang D, Prager BC, Gimple RC, Yu J, Zhao W, Wu Q, Zhang W, Wu E, Chen X, Luo J, Rich JN, Xie Q, Jiang T, Chen R. Nat Commun. 2023 Nov 18;14(1):7526. doi: 10.1038/s41467-023-43113-5. PubMed |
| A functional genomic framework to elucidate novel causal non-alcoholic fatty liver disease genes. Saliba-Gustafsson P, Justesen JM, Ranta A, Sharma D, Bielczyk-Maczynska E, Li J, Najmi LA, Apodaka M, Aspichueta P, Bjorck HM, Eriksson P, Franco-Cereceda A, Gloudemans M, Mujica E, den Hoed M, Assimes TL, Quertermous T, Carcamo-Orive I, Park CY, Knowles JW. medRxiv [Preprint]. 2024 Feb 4:2024.02.03.24302258. doi: 10.1101/2024.02.03.24302258. PubMed |
| The construction of modular universal chimeric antigen receptor T (MU-CAR-T) cells by covalent linkage of allogeneic T cells and various antibody fragments. Chen T, Deng J, Zhang Y, Liu B, Liu R, Zhu Y, Zhou M, Lin Y, Xia B, Lin K, Ma X, Zhang H. Mol Cancer. 2024 Mar 11;23(1):53. doi: 10.1186/s12943-024-01938-8. PubMed |
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