Addgene: pSAG1::CAS9-U6::sgUPRT Citations

pSAG1::CAS9-U6::sgUPRT Citations (55)

Originally described in: Efficient Gene Disruption in Diverse Strains of Toxoplasma gondii Using CRISPR/CAS9.
Shen B, Brown KM, Lee TD, Sibley LD MBio. 2014 May 13;5(3). pii: e01114-14. doi: 10.1128/mBio.01114-14. PubMed Journal

Articles Citing pSAG1::CAS9-U6::sgUPRT

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Toxoplasma gondii chitinase-like protein TgCLP1 regulates the parasite cyst burden. Bando H, Murata Y, Han Y, Sugi T, Fukuda Y, Bzik DJ, Fox BA, Kato K. Front Cell Infect Microbiol. 2024 May 17;14:1359888. doi: 10.3389/fcimb.2024.1359888. eCollection 2024. PubMed
TBC9, an essential TBC-domain protein, regulates early vesicular transport and IMC formation in Toxoplasma gondii. Sun M, Tang T, He K, Long S. Commun Biol. 2024 May 18;7(1):596. doi: 10.1038/s42003-024-06310-6. PubMed
Myosin F controls actin organization and dynamics in Toxoplasma gondii. Kellermeier JA, Heaslip AT. Mol Biol Cell. 2024 Apr 1;35(4):ar57. doi: 10.1091/mbc.E23-12-0510. Epub 2024 Feb 28. PubMed
Small RNAs from mitochondrial genome recombination sites are incorporated into T. gondii mitoribosomes. Tetzlaff S, Hillebrand A, Drakoulis N, Gluhic Z, Maschmann S, Lyko P, Wicke S, Schmitz-Linneweber C. Elife. 2024 Feb 16;13:e95407. doi: 10.7554/eLife.95407. PubMed
An apicoplast-localized deubiquitinase contributes to the cell growth and apicoplast homeostasis of Toxoplasma gondii. Xia J, Yang Y, Chen X, Song K, Ma G, Yang Y, Yao C, Du A. Vet Res. 2024 Jan 17;55(1):10. doi: 10.1186/s13567-023-01261-y. PubMed
Susceptibility of Toxoplasma gondii to autophagy in human cells relies on multiple interacting parasite loci. Rinkenberger N, Rosenberg A, Radke JB, Bhushan J, Tomita T, Weiss LM, Sibley LD. mBio. 2024 Jan 16;15(1):e0259523. doi: 10.1128/mbio.02595-23. Epub 2023 Dec 14. PubMed
F-actin and myosin F control apicoplast elongation dynamics which drive apicoplast-centrosome association in Toxoplasma gondii. Devarakonda PM, Sarmiento V, Heaslip AT. mBio. 2023 Oct 31;14(5):e0164023. doi: 10.1128/mbio.01640-23. Epub 2023 Sep 21. PubMed
A screen of drug-like molecules identifies chemically diverse electron transport chain inhibitors in apicomplexan parasites. Hayward JA, Makota FV, Cihalova D, Leonard RA, Rajendran E, Zwahlen SM, Shuttleworth L, Wiedemann U, Spry C, Saliba KJ, Maier AG, van Dooren GG. PLoS Pathog. 2023 Jul 20;19(7):e1011517. doi: 10.1371/journal.ppat.1011517. eCollection 2023 Jul. PubMed
An essential role for an Fe-S cluster protein in the cytochrome c oxidase complex of Toxoplasma parasites. Leonard RA, Tian Y, Tan F, van Dooren GG, Hayward JA. PLoS Pathog. 2023 Jun 1;19(6):e1011430. doi: 10.1371/journal.ppat.1011430. eCollection 2023 Jun. PubMed
Pantothenate biosynthesis in Toxoplasma gondii tachyzoites is not a drug target. Howieson VM, Zeng J, Kloehn J, Spry C, Marchetti C, Lunghi M, Varesio E, Soper A, Coyne AG, Abell C, van Dooren GG, Saliba KJ. Int J Parasitol Drugs Drug Resist. 2023 Aug;22:1-8. doi: 10.1016/j.ijpddr.2023.03.003. Epub 2023 Mar 15. PubMed

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