...human muscarinic receptors: hM1Dq, hM3Dq, and hM5Dq, however, hM3Dq is the most widely employed. Gi-DREADDs...SALB). Scientists have shown that both KORD and hM3Dq can be used in the same organism to allow bidirectional...translocation Arrestin signalling Nakajima & Wess, 2012 hM3Dq hM1Dq hM5Dq Human M3 muscarinic G αq CNO* Increase...genetically engineered animal models expressing hM3Dq, hM4Di, and rM3D DREADDs have been developed and...