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Right variable region, but wrong constant? Chimeric antibodies may be the answer!

April 25, 2023, 1:15 p.m.

Viral genome sequencing is a high-throughput method for determining AAV transgene identity and confirming the serotype.

April 23, 2020, 1:15 p.m.

TOPO cloning is a restriction enzyme and ligase free cloning method. Learn how TOPO works in this post.

Oct. 27, 2016, 2:30 p.m.

Learn about the differences in virus production between insect cells and mammalian cells.

Nov. 5, 2024, 8:32 p.m.

Learn about the structure and life cycle of retroviruses to help understand how to use viral vectors tools in the lab.

July 27, 2023, 1:15 p.m.

Chromoproteins are a subset of the fluorescent protein family. They give strong color in visible light and can be used for molecular biology experiments.

Feb. 4, 2020, 2:15 p.m.

Antibiotic resistant bacteria are a huge issue in the clinic - learn how CRISPR is being developed to fight against antibiotic resistant super bugs.

May 3, 2016, 2:30 p.m.

Need help with the plasmid deposit process at Addgene? Consult this post for an in-depth walk through the entire process.

Feb. 27, 2024, 2:15 p.m.

Plasmids from Addgene encoding SARS-CoV-2 spike protein variants can be used to study antibody neutralization escape.

June 22, 2021, 1:15 p.m.

Learn what the Gal4/UAS system is and how it can enable powerful experiments in Drosophila.

July 21, 2017, 12:48 p.m.

Want to show how often your plasmids are requested? Or where they're being shipped to? The depositor-developed Addgene Request dashboard can help!

April 11, 2023, 4 p.m.

Learn how stem cell researchers use reprogramming and transdifferentiation techniques to convert cells from one type into another.

Nov. 6, 2018, 1:12 p.m.

Discover the history of Rett Syndrome research, the role of the MECP2 gene, and some of the latest breakthrough therapeutic approaches for Rett Syndrome.

Nov. 19, 2020, 2:15 p.m.

Learn how a new episomal plasmid-based method can be used to efficiently reprogram blood cells to induced pluripotent stem cells

Dec. 14, 2017, 2:08 p.m.

The Framework for In vivo T cell Screens (FITS) allows for in vivo CRISPR screening in T cells. Learn more about FITS in our blog post.

May 2, 2024, 1:15 p.m.

Learn how you can use the Broad Target Accelerator Plasmid Collections from to help enable precision cancer medicine research.

May 11, 2017, 2:30 p.m.

New CRISPR pooled libraries, such as SAM, CRISPRa, and CRISPRi, offer new ways to do genome-wide functional screens.

Feb. 24, 2015, 7:50 p.m.

Addgene has a new brand identity! This post describes the design decisions that went into our new logo, style, introductory video, and our mascot, Blugene.

April 28, 2026, 1:15 p.m.

This post highlights some of the tools Addgene makes available to industry scientists.

Jan. 13, 2026, 2:15 p.m.

Addgene is excited to announce its very first AAV Data Hub Challenge.

Sept. 20, 2022, 1:15 p.m.