Plasmids 101: Codon usage bias
Type
Blog Post
Published
Sept. 27, 2018, 1:09 p.m.
...example Tuller et al. found that translation efficiency is well correlated with codon bias in both E. coli...therefore may need fewer resources for the entire translation process. For example, during high growth rate...rate conditions, E. coli preferentially upregulates production of tRNAs that recognize codons found in highly...tRNAs, different regions of the protein may be translated at different rates. The ribosome will move quickly...the ribosome stalls, this may give the swiftly translated regions a chance to fold properly. For example...with specific secondary structures in 10 closely related yeast strains.
Adaptation to changing conditions...codon preferences online). Even if the gene is translated, it may not function properly. This is the result...