CRISPR 101: RNA Editing with Cas13
Type
Blog Post
Published
July 31, 2020, 12:30 p.m.
...would convert adenine to inosine, which the translational machinery treats like guanine. This RNA editor...would permit point mutations in RNA which could recapitulate or rescue known pathogenic alleles, or introduce...ADAR will preferentially edit an adenine if the template has a cytosine mismatch at that position.
PspCas13b-ADAR2DD...RNA Editing Capabilities through RESCUE
Two years later, the Zhang lab expanded the RNA editing toolkit ...