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X-CHIME, a series of CRISPR tools developed and deposited by Arlene Sharpe's lab, allows for germline knockouts in immune cells in mice.

This post describes the development of sentinel plants, which change color to alert humans when they detect certain molecules in their environment.

Looking to use adenoviral vectors in your research? This post introduces you to the adenovius!

Scientists at Beam Therapeutics have found a way to improve editing in primary human cells using evolved adenine base editors called ABE8.

Addgene's interviews Chris Voigt of MIT about the intersection of CRISPR and synthetic biology and his new work building circuits with CRISPRs.

Learn more about non-homologous end joining (NHEJ) and how it relates to genome engineering technologies such as CRISPR/Cas9.

CRISPR-Cas9 technology appears in numerous publications, including its use for genome editing in monkeys and x-ray crystallography of Cas9's 3-D shape.

Ready to produce rAAV in your own lab? This 101 post can help!

The tumor microenvironment is the cellular milieu that surrounds a tumor and contains immune cells, blood vessels, cells, and signaling molecules. What goes on in the cancer microenvironment affects and is affected and can either promote or repress tumor growth.

Learn how AAVs can be used to trace neuronal connections.

With the limitations of qRT-PCR based COVID-19 testing, scientists develop CRISPR-based diagnostic tools for COVID-19.

The NeuroMab Facility and James Trimmer have produced monoclonal antibodies validated for neuroscience research. Find plasmids encoding these R-mAbs here.

The Doudna lab recently described a new, thermostable Cas9 variant, GeoCas9. Learn how you can use GeoCas9 in your next genome engineering experimetn.

This post discusses takeaways from, and tools presented at, the Deaminet 2026 conference, focusing on base editors, prime editors, and translational work.

This post highlights ways to overcome the AAV size limitation to deliver CRISPR editing tools to cells.

Discover the best situations to use Cas9 activators in your experiments with tips from their creators.

Browse Ginkgo Bioworks plasmids to express SARS-CoV-2 viral proteins in several expression systems.

Learn about the latest statistics on CRISPR plasmid deposits and distributions and how this reflects the broader CRISPR community.

Find the basics about chemogenetics: what are chemogenetics, why use them, and how to build your chemogenetic system using receptors and ligands.

Learn how Cpf1 stacks up against Cas9 and NgAgo