Starter Guide to induced Pluripotent Stem Cells (iPSCs) Part 2: Reprogramming and Transdifferentiation
Type
Blog Post
...cells. The goal is to use cells that can be easily isolated from donors. Apart from fibroblasts, human keratinocytes...epithelial cells from urine are some of the easily isolated somatic cells that have been reprogrammed to iPSCs...the reprogramming factors)
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Chances of accumulation of harmful mutations
More, due to selection ...from human pluripotent stem cells via temporal modulation of canonical Wnt signaling. Proc Natl Acad Sci...