We narrowed to 597 results for: arl
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TypeBlog Post...on gene therapy for viral infections. She is particularly passionate about HIV cure research and science...
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A New Generation of Adenine Base Editors Improves Editing in Primary Human Cells
TypeBlog Post...and TadA7.10, they designed one set of ABE8’s similarly (ABE8.x-d). In order to assess the effect of removing... -
Plasmid-based Recombinant Monoclonal Antibodies: What They Are and Why You Should Be Excited About Them
TypeBlog Post...US alone (Bradbury & Plückthun, 2015a). With molecularly defined antibodies that do not change over time... -
Plasmids 101: In-house NGS Plasmid Quality Control Now at Addgene
TypeBlog Post... There are regions of some plasmids that are particularly difficult to sequence and assemble, including... -
Hot Plasmids and Viral Preps - March 2021
TypeBlog Post... New from the viral service By Jason Nasse We regularly add new viral aliquots from our plasmid collection... -
Viral Vectors 101: Calcium Sensors
TypeBlog Post... aims and requirements of in vivo studies. A particularly useful sensor for neuroscientists is CaMPARI... -
High Complexity Golden Gate Assembly with NEB’s DAD
TypeBlog Post...rules the best way to design GGA overhang sets, particularly for high-complexity reactions? The researchers... -
Viral Vectors 101: Virus Safety
TypeBlog Post...researcher to come into contact with than GFP. Similarly, if the viral vector carries an shRNA to a gene... -
Antibodies 101: Choosing the Right Isotype
TypeBlog Post... better for probing poorly expressed targets. Similarly, rabbit derived antibodies may be the better choice... -
Open Resources and Plasmid Tools For Studying C. elegans
TypeBlog Post...frequently for what’s new and popular! References Hammarlund, Marc, et al. "The CeNGEN Project: The Complete... -
Getting Started with Behavioral Neuroscience: Standardizing Experiments and Using Viral Vectors
TypeBlog Post...activity, commonly via light-activated ion channels. Similarly, chemogenetic tools are designed channels that... -
Hot Plasmids and Viral Preps - January 2021
TypeBlog Post... New from the viral service By Jason Nasse We regularly add new viral aliquots from our plasmid collection... -
Corralling and Cornering the Goldilocks Antibody
TypeBlog Post...from the background noise. If the sample images similarly to the negative control, that informs us that ... -
Hot Plasmids February 2024
TypeBlog Post...Cas12-RNP-PAGE achieved high editing frequency (nearly 100% in some cases) and minimal toxicity, including... -
Fluorescent Proteins 101: Introduction to FRET
TypeBlog Post... 1103-1111. PubMed PMID: 27475975. 6. Gayrard, Charlène, and Borghi, Nicolas. "FRET-based molecular tension... -
Plasmids for Endogenous Gene Tagging in Human Cells
TypeBlog Post...location in the genome is still inefficient, particularly in human cell lines. Furthermore, the quality... -
6 Tips for Grant Writing
TypeBlog Post...increase your success rate. 1. Submit your grant early! First off, and perhaps the most important bit of... -
Cpf1 Update: Comparison to Cas9 and NgAgo
TypeBlog Post.... Sticky-end mediated gene transfer would be particularly helpful for targeting non-dividing cells, which... -
Plasmids 101: Terminators and PolyA signals
TypeBlog Post...additional references are provided at the end. Nearly all common bacterial expression plasmids use Rho-independent... -
Tips for Titering Your Lentiviral Preps
TypeBlog Post...serial dilutions of a viral prep. This method is particularly useful when vectors carrying fluorescent markers...