We narrowed to 593 results for: arl

1. Improving Transduction Efficiency with Exosome AAVs

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   Blog Post

   ...to neutralizing anti-AAV antibodies. This is particularly useful for therapeutic applications in vivo ...

2. Addgene-Seeding Labs plasmid grant round 3: microbial drug resistance and biofilms, antidiabetic plant components, visualizing brain injury - and a glowing robot fish

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   ...tuberculosis) and in identifying new drug targets. An early and accurate detection of PZA-resistance is necessary...

3. Unique and persistent IDs for improved reproducibility: Addgene now supports RRIDs and compact identifiers for all plasmids

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   ...unique PID is the Digital Object Identifier (DOI). Nearly all the papers or preprints you read or produce...

4. Cultivating Community Science at BosLab

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   ...Some are entrepreneurs using our space to perform early-stage experiments. For example, Dave Grawoig is ...

5. Choosing Your Fluorescent Proteins for Multi-Color Imaging

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   ...contain all fluorescent proteins in common use (particularly not the most recently published ones), they ...

6. Finding and Joining Your Dream Lab

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   Blog Post

   ...Alternatively, perhaps the lab publishes and presents regularly with labs around the world. You may prefer a more...

7. Plasmids 101: Mammalian Vectors

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   Blog Post

   .... Positive selection in mammalian cells works similarly to that in bacteria and a table of the most commonly...

8. Plasmids 101: Sequence and Ligation Independent Cloning (SLIC)

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   ...researchers doing large amounts of cloning. Assembly is scarless, unlike Gateway cloning, and the method’s flexibility...

9. Cas13d: Small RNA-targeting CRISPR enzymes for transcriptome engineering

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   ...the ratio of pathogenic to non-pathogenic tau by nearly 50%, showing proof-of-concept for pre-clinical ...

10. Viral Vectors 101: Types of viruses

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    ...to specific cell types of interest. This is a particularly nice feature as organ-specific injections, or...

11. Viral Vectors 101: The AAV Retrograde Serotype

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    ...these vectors can exhibit spurious expression, particularly at the injection site (Fischer, KB. 2019). The...

12. A Deep Dive into BioBuilder

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    ...teacher professional development program that trains nearly 100 teachers each year, with workshops held at ...

13. Enabling Precision Functional Genomics with the Target Accelerator Plasmid Collection

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    Blog Post

    ...PMC5120861. While there is much work to do, these early pilot studies have demonstrated technical feasibility...

14. Opto-Nanobodies: Using Light to Manipulate Cell Signaling and Protein Purification

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    Blog Post

    ...light-based control of signaling pathways. This is particularly exciting because using light to control signaling...

15. Choosing a CRISPR Nuclease: Site Accessibility, Specificity, and Sensitivity

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    Blog Post

    ...NG (Nishimasu et al., 2018). The David Liu Lab similarly described xCas9, which displayed the ability to...

16. Antibodies 101: Monoclonal Antibodies

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    ...for your experiment Monoclonal antibodies are particularly useful when you want to ensure that the antibody...

17. 7 Tips to Secure a STEAM Internship This Summer

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    Blog Post

    ...Addgene blog Check out other tools and resources for early career researchers Applying for jobs? Check out ...

18. How Addgene Creates Content

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    Blog Post

    ...final check before publication.   Do research! Nearly everything we write entails a primary literature...

19. Plasmids 101: Screens vs. Selections

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    Blog Post

    ...both a screen and a selection, it is important to clearly define what type of factor you are looking for ...

20. AAV Q&A with Tim Miles

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    Blog Post

    ...Would you recommend any liver specific capsid, particularly one that can target the epithelial cells in ...