Genetically-encoded Sparse Cell Labeling - A SPARC of Innovation
Type
Blog Post
...cells that will be labeled in a given population is directly correlated to the length of the truncated attP...subset of cells. By labeling fewer cells in a population, it’s easier to visualize individual/non-overlapping...transgenic animals are commonly used to specifically manipulate a cell type of interest in an organism, all cells...strategy results in sparse labeling of the cell population that expresses SPARC and the fraction of cells...intermediate (I), or sparse (S) labeling of the cell population.
Figure 2: Dense (c), intermediate (d),...Clandinin TR (2019) SPARC: a method to genetically manipulate precise proportions of cells. bioRxiv 788679;...