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Sabatini/Lander Lab Activity-Optimized Genome-wide Mouse sgRNA Library in pLenti-sgRNA

Pooled Library

#1000000096

Purpose

CRISPR gRNA knockout pooled library for targeting the mouse genome

Depositor

Eric Lander, David Sabatini

Available since

April 3, 2017

Availability

Academic Institutions and Nonprofits only
Sabatini/Lander Lab Activity-Optimized Genome-wide Human sgRNA Library in pLenti-sgRNA

Pooled Library

#1000000095

Purpose

CRISPR gRNA knockout pooled library for targeting the human genome

Depositor

Eric Lander, David Sabatini

Available since

April 3, 2017

Availability

Academic Institutions and Nonprofits only
Human Whole Genome sgRNA iBAR Library

Pooled Library

#140633

Purpose

CRISPR pooled screen at high MOI by the embedded internal barcodes

Depositor

Wensheng Wei

Article

Zhu et al Genome Biol. 2019 Jan 24;20(1):20. doi:

Use

CRISPR and Lentiviral

Available since

April 21, 2020

Availability

Academic Institutions and Nonprofits only
Human Transporter Knockout Library with UMIs

Pooled Library

#221409

Purpose

gRNA library to test the impact of transporters on biological processes

Depositor

RESOLUTE Consortium, Giulio Superti-Furga

Article

Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Sept. 13, 2024

Availability

Academic Institutions and Nonprofits only
The Human Druggable CRISPR library

Pooled Library

#200013

Purpose

The library contains ~10,000 sgRNAs targeting 1,980 human genes (5 sgRNAs per gene and 100 nontargeting control sgRNAs).

Depositor

Lianxin Liu

Article

Zheng et al Adv Sci (Weinh). 2023 Aug;10(22):e220679

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

May 9, 2023

Availability

Academic Institutions and Nonprofits only
Splicing-targeting CRISPR-Cas9 library for human lncRNAs

Pooled Library

#119977

Purpose

The CRISPR sgRNA library was designed to target the 5' or 3' splice sites of lncRNAs in genome-scale, in order to knockout the targeted lncRNAs.

Depositor

Wensheng Wei

Article

Liu et al Nat Biotechnol. 2018 Nov 5. pii: nbt.428

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

March 27, 2019

Availability

Academic Institutions and Nonprofits only
Human ABC Transporter Knockout Sub-library with UMIs

Pooled Library

#221410

Purpose

gRNA library to test the impact of transporters on biological processes (subset: ABC transporters and controls)

Depositor

RESOLUTE Consortium, Giulio Superti-Furga

Article

Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Sept. 13, 2024

Availability

Academic Institutions and Nonprofits only
BARBEKO sgRNA library

Pooled Library

#174163

Purpose

iBARed cytosine Base Editing-mediated gene KnockOut (BARBEKO) sgRNA library; This library leverages CRISPR cytosine base editors for genome-scale knockout screens.

Depositor

Wensheng Wei

Article

Xu et al Nat Biotechnol. 2021 Jun 21. pii: 10.103

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Aug. 31, 2021

Availability

Academic Institutions and Nonprofits only
Human Cas13 Pooled Long-Noncoding RNA (lncRNA) Library

Pooled Library

#227014

Purpose

CRISPR-Cas13 lentiviral pooled library targeting human lncRNAs and their closest protein-coding genes for transcriptome-wide knockdown screens.

Depositor

Neville Sanjana

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Feb. 11, 2025

Availability

Academic Institutions and Nonprofits only
Mouse Liver CRISPR Knockout Library

Pooled Library

#192824

Purpose

CRISPR screening library containing ~72,000 sgRNAs

Depositor

Kristin Knouse

Article

Keys et al Cell Genom. 2022 Dec 14;2(12):100217. do

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available since

Dec. 1, 2022

Availability

Academic Institutions and Nonprofits only
Human CRISPR Metabolic Gene Knockout Library

Pooled Library

#110066

Purpose

Encodes gRNAs for targeting metabolic genes in CRISPR screens.

Depositor

David Sabatini

Article

Birsoy et al Cell. 2015 Jul 30;162(3):540-51. doi: 10

Use

Lentiviral

Available since

May 4, 2018

Availability

Academic Institutions and Nonprofits only
Human Transporter Knockout library

Pooled Library

#213695

Purpose

Next generation transporter-focused CRISPR/Cas9 library targeting transmembrane transporters to test the impact of transporters on biological processes.

Depositor

RESOLUTE Consortium, Giulio Superti-Furga

Article

Ferdigg et al Life Sci Alliance. 2024 Nov 22;8(2):e202

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Sept. 13, 2024

Availability

Academic Institutions and Nonprofits only
Pan-cancer CasRx lncRNA Albarossa library

Pooled Library

#212966

Purpose

The human CasRx CRISPR lentiviral library encodes 75,725 gRNA arrays (two gRNAs per array) targeting 24,171 lncRNAs.

Depositor

Roland Rad

Article

Montero et al Nat Methods. 2024 Feb 26. doi: 10.1038/s

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Feb. 21, 2024

Availability

Academic Institutions and Nonprofits only

Showing: 1 - 13 of 13 results

Results per page:

Sort results by:

Sabatini/Lander Lab Activity-Optimized Genome-wide Mouse sgRNA Library in pLenti-sgRNA

Sabatini/Lander Lab Activity-Optimized Genome-wide Human sgRNA Library in pLenti-sgRNA

Human Whole Genome sgRNA iBAR Library

Human Transporter Knockout Library with UMIs

The Human Druggable CRISPR library

Splicing-targeting CRISPR-Cas9 library for human lncRNAs

Human ABC Transporter Knockout Sub-library with UMIs

BARBEKO sgRNA library

Human Cas13 Pooled Long-Noncoding RNA (lncRNA) Library

Mouse Liver CRISPR Knockout Library

Human CRISPR Metabolic Gene Knockout Library

Human Transporter Knockout library

Pan-cancer CasRx lncRNA Albarossa library

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