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Human Base Editing Sensor Library

Pooled Library

#179218

Purpose

sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

Depositor

Lukas Dow

Article

Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

Expression

Mammalian

Use

Lentiviral

Available since

June 16, 2022

Availability

Academic Institutions and Nonprofits only
Mouse Base Editing Sensor Library

Pooled Library

#179217

Purpose

sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

Depositor

Lukas Dow

Article

Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

Expression

Mammalian

Use

Lentiviral

Available since

June 16, 2022

Availability

Academic Institutions and Nonprofits only
Sctrans-PP

Pooled Library

#153101

Purpose

CRISPR library targets all non-essential and conditionally essential transporter genes in S. cerevisiae

Depositor

Irina Borodina

Article

Wang et al Metab Eng. 2021 Jan 16. pii: S1096-7176(

Expression

Yeast

Species

Saccharomyces cerevisiae

Use

CRISPR

Available since

Jan. 20, 2021

Availability

Academic Institutions and Nonprofits only
Sctrans-PP-Grp1

Pooled Library

#153102

Purpose

CRISPR library targets a sub-pool of transporter genes in S. cerevisiae

Depositor

Irina Borodina

Article

Wang et al Metab Eng. 2021 Jan 16. pii: S1096-7176(

Expression

Yeast

Species

Saccharomyces cerevisiae

Use

CRISPR

Available since

Jan. 20, 2021

Availability

Academic Institutions and Nonprofits only
Sctrans-PP-Grp2

Pooled Library

#153103

Purpose

CRISPR library targets a sub-pool of transporter genes in S. cerevisiae

Depositor

Irina Borodina

Article

Wang et al Metab Eng. 2021 Jan 16. pii: S1096-7176(

Expression

Yeast

Species

Saccharomyces cerevisiae

Use

CRISPR

Available since

Jan. 20, 2021

Availability

Academic Institutions and Nonprofits only
Sctrans-PP-Grp3

Pooled Library

#153104

Purpose

CRISPR library targets a sub-pool of transporter genes in S. cerevisiae

Depositor

Irina Borodina

Article

Wang et al Metab Eng. 2021 Jan 16. pii: S1096-7176(

Expression

Yeast

Species

Saccharomyces cerevisiae

Use

CRISPR

Available since

Jan. 20, 2021

Availability

Academic Institutions and Nonprofits only
Sctrans-PP-Grp4

Pooled Library

#153105

Purpose

CRISPR library targets a sub-pool of transporter genes in S. cerevisiae

Depositor

Irina Borodina

Article

Wang et al Metab Eng. 2021 Jan 16. pii: S1096-7176(

Expression

Yeast

Species

Saccharomyces cerevisiae

Use

CRISPR

Available since

Jan. 20, 2021

Availability

Academic Institutions and Nonprofits only
Sctrans-PP-Grp5

Pooled Library

#153106

Purpose

CRISPR library targets a sub-pool of transporter genes in S. cerevisiae

Depositor

Irina Borodina

Article

Wang et al Metab Eng. 2021 Jan 16. pii: S1096-7176(

Expression

Yeast

Species

Saccharomyces cerevisiae

Use

CRISPR

Available since

Jan. 20, 2021

Availability

Academic Institutions and Nonprofits only
Pan-Druggable Cancer Library

Pooled Library

#182133

Purpose

All-in-one CRISPR/Cas system with 74 individual elements. 63 elements target cancer-related genes with FDA-approved drug treatments, and 3 elements target key medulloblastoma driver genes.

Depositor

Prashant Mali

Article

Hu et al Biomaterials. 2022 Jan;280:121276. doi:

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Aug. 26, 2022

Availability

Academic Institutions and Nonprofits only
FNLCR CRISPRa Cell Surface

Pooled Library

#207471

Purpose

CRISPR-based activation library with guide RNAs targeting all cell surface proteins.

Depositor

Raj Chari

Article

Yang et al Sci Adv. 2024 Feb 16;10(7):eadj2445. doi

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Jan. 24, 2024

Availability

Academic Institutions and Nonprofits only
ALL-PAM sensor Library

Pooled Library

#179219

Purpose

10 human and mouse sgRNAs each where for each sgRNA the tethered target site has 1 of 64 possible 3 bp PAM sequences.

Depositor

Lukas Dow

Article

Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

Expression

Mammalian

Use

Lentiviral

Available since

June 16, 2022

Availability

Academic Institutions and Nonprofits only
LV2btCRISPRko.v1

Pooled Library

#213927

Purpose

Uses lentivirus to deliver the library into hard-to-transduce cells

Depositor

Wenfang Spring Tan

Article

Tan et al PLoS Pathog. 2023 Dec 6;19(12):e1011822.

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

April 9, 2024

Availability

Academic Institutions and Nonprofits only
pMuSIC pool v1.0

Pooled Library

#227193

Purpose

Two-way barcodes from 18 fluorescent proteins for mammalian expression. Can be used for clone tracing, or for pairing with perturbations for single cell resolution in spectral detection measurements.

Depositor

Marc Birtwistle

Article

Lu et al bioRxiv [Preprint]. 2024 Oct 24:2024.10.

Expression

Mammalian

Available since

Dec. 18, 2024

Availability

Academic Institutions and Nonprofits only
PBbtCRISPRko.v1

Pooled Library

#213928

Purpose

Uses the PiggyBac transposon system to deliver the library into hard to transduce cells

Depositor

Wenfang Spring Tan

Article

Tan et al PLoS Pathog. 2023 Dec 6;19(12):e1011822.

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

April 9, 2024

Availability

Academic Institutions and Nonprofits only
Pdest-EF1α-EGFP-32bp barcode polyA library

Pooled Library

#211610

Purpose

Barcoded retrovirus plasmid library for capturing the transcriptome and viral barcode sequences of individual cells to infer their identities and lineage information.

Depositor

Yuejun Chen

Article

You et al Cell Stem Cell. 2023 Apr 6;30(4):473-487

Species

Synthetic

Use

Retroviral

Available since

Aug. 29, 2024

Availability

Academic Institutions and Nonprofits only
p11-3’_8xN_PAM-site1 (RTW554)

Pooled Library

#160132

Purpose

Plasmid library harboring a randomized 8nt PAM 3’ of target site 1. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 3’ PAMs (e.g. Cas9)

Depositor

Benjamin Kleinstiver, Keith Joung

Article

Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

Species

Synthetic

Use

CRISPR

Available since

Feb. 8, 2021

Availability

Academic Institutions and Nonprofits only
p11-5’_10xN_PAM-site4 (RTW574)

Pooled Library

#160135

Purpose

Plasmid library harboring a randomized 10nt PAM 5’ of target site 4. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 5’ PAMs (e.g. Cas12a)

Depositor

Benjamin Kleinstiver, Keith Joung

Article

Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

Species

Synthetic

Use

CRISPR

Available since

Feb. 8, 2021

Availability

Academic Institutions and Nonprofits only
p11-3’_8xN_PAM-site2 (RTW555)

Pooled Library

#160133

Purpose

Plasmid library harboring a randomized 8nt PAM 3’ of target site 2. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 3’ PAMs (e.g. Cas9)

Depositor

Benjamin Kleinstiver, Keith Joung

Article

Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

Species

Synthetic

Use

CRISPR

Available since

Feb. 8, 2021

Availability

Academic Institutions and Nonprofits only
Oxford Drosophila melanogaster Genome-wide CRISPR Library

Pooled Library

#64750

Purpose

A genome-wide CRISPR library covering 13,501 genes (98.8% of the Drosophila melanogaster genome), among which 8,989 genes are targeted by three or more independent single guide RNAs (sgRNAs).

Depositor

Ji-Long Liu

Article

Bassett et al J Genet Genomics. 2015 Jun 20;42(6):301-

Expression

Insect

Species

Drosophila melanogaster, Streptococcus pyogenes, and Synthetic

Use

CRISPR

Available since

March 7, 2016

Availability

Academic Institutions and Nonprofits only
Toronto KnockOut version 3 library (TKOv3)

Pooled Library

#90294

Purpose

Optimized library offering improved accuracy, efficiency, and scalability for CRISPR screens compared to TKOv1

Depositor

Jason Moffat

Article

Hart et al G3 (Bethesda). 2017 Aug 7;7(8):2719-2727

Available since

May 5, 2017

Availability

Academic Institutions and Nonprofits only

Showing: 1 - 20 of 20 results

Results per page:

Sort results by:

Human Base Editing Sensor Library

Mouse Base Editing Sensor Library

Sctrans-PP

Sctrans-PP-Grp1

Sctrans-PP-Grp2

Sctrans-PP-Grp3

Sctrans-PP-Grp4

Sctrans-PP-Grp5

Pan-Druggable Cancer Library

FNLCR CRISPRa Cell Surface

ALL-PAM sensor Library

LV2btCRISPRko.v1

pMuSIC pool v1.0

PBbtCRISPRko.v1

Pdest-EF1α-EGFP-32bp barcode polyA library

p11-3’_8xN_PAM-site1 (RTW554)

p11-5’_10xN_PAM-site4 (RTW574)

p11-3’_8xN_PAM-site2 (RTW555)

Oxford Drosophila melanogaster Genome-wide CRISPR Library

Toronto KnockOut version 3 library (TKOv3)

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