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Yeast Inducible CRISPRi Library

Pooled Library

#161829

Purpose

ATc inducbile yeast CRISPRi library

Depositor

Saeed Tavazoie

Article

Momen-Roknabadi et al Commun Biol. 2020 Nov 27;3(1):723. doi:

Expression

Yeast

Species

Saccharomyces cerevisiae

Use

CRISPR

Available since

April 28, 2021

Availability

Academic Institutions and Nonprofits only
Membrane protein gRNA library

Pooled Library

#113345

Purpose

Contains 58,071 gRNAs targeting 6,213 membrane proteins and 500 non-targeting gRNAs

Depositor

Gavin Wright

Article

Chong et al Genome Biol. 2018 Nov 26;19(1):205. doi:

Species

Homo sapiens

Use

Lentiviral

Available since

Jan. 4, 2019

Availability

Academic Institutions and Nonprofits only
Human ubiquitination-related proteins CRISPR KO library

Pooled Library

#174592

Purpose

CRISPR Cas9 KO library targets 660 ubiquitination-related proteins, including all major E1, E2, E3 and deubiquitinating enzymes, as well as other ubiquitination-related proteins.

Depositor

Juan Bonifacino

Article

Jia et al Elife. 2019 Nov 6;8. pii: 50034. doi: 10

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Nov. 30, 2021

Availability

Academic Institutions and Nonprofits only
Human Transporter Knockout library

Pooled Library

#213695

Purpose

Next generation transporter-focused CRISPR/Cas9 library targeting transmembrane transporters to test the impact of transporters on biological processes.

Depositor

Giulio Superti-Furga, RESOLUTE Consortium

Article

Ferdigg et al Life Sci Alliance. 2024 Nov 22;8(2):e202

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Sept. 13, 2024

Availability

Academic Institutions and Nonprofits only
StopPR epegRNA library (lAC002)

Pooled Library

#227706

Purpose

CRISPR guide RNA library for prime editing

Depositor

Brittany Adamson

Article

Cirincione et al Nat Methods. 2024 Nov 19. doi: 10.1038/s

Expression

Mammalian

Use

Lentiviral

Available since

Jan. 23, 2025

Availability

Academic Institutions and Nonprofits only
pRep-Cap Scanning Saturation Mutagenesis (SSM) pooled library

Pooled Library

#199601

Purpose

pRep-Cap SSM library enables VP1, VP2, and VP3 expression under the control of the endogenous p40 promoter

Depositor

George Church

Article

Ogden et al Science. 2019 Nov 29;366(6469):1139-1143

Expression

Mammalian

Species

Aav2

Use

AAV

Available since

June 13, 2023

Availability

Academic Institutions and Nonprofits only
Self-targeting epegRNA library, +5 G>H (lDS004)

Pooled Library

#227707

Purpose

CRISPR guide RNA library for prime editing

Depositor

Brittany Adamson

Article

Cirincione et al Nat Methods. 2024 Nov 19. doi: 10.1038/s

Expression

Mammalian

Use

Lentiviral

Available since

Jan. 23, 2025

Availability

Academic Institutions and Nonprofits only
Self-targeting epegRNA library, Tiled edits (lRM001)

Pooled Library

#227708

Purpose

CRISPR guide RNA library for prime editing

Depositor

Brittany Adamson

Article

Cirincione et al Nat Methods. 2024 Nov 19. doi: 10.1038/s

Expression

Mammalian

Use

Lentiviral

Available since

Jan. 23, 2025

Availability

Academic Institutions and Nonprofits only
Splicing-targeting CRISPR-Cas9 library for human lncRNAs

Pooled Library

#119977

Purpose

The CRISPR sgRNA library was designed to target the 5' or 3' splice sites of lncRNAs in genome-scale, in order to knockout the targeted lncRNAs.

Depositor

Wensheng Wei

Article

Liu et al Nat Biotechnol. 2018 Nov 5. pii: nbt.428

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

March 27, 2019

Availability

Academic Institutions and Nonprofits only
MYC-CRISPR

Pooled Library

#173195

Purpose

This pooled lentiviral CRISPR knockout library targets E-boxes genome-wide and can be applied for identification of essential MYC binding sites in a wide range of human cells.

Depositor

Agnieszka Dzikiewicz-Krawczyk

Article

Kazimierska et al Mol Oncol. 2023 Nov;17(11):2295-2313. do

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Aug. 11, 2021

Availability

Academic Institutions and Nonprofits only
Mouse Liver CRISPR Knockout Library

Pooled Library

#192824

Purpose

CRISPR screening library containing ~72,000 sgRNAs

Depositor

Kristin Knouse

Article

Keys et al Cell Genom. 2022 Dec 14;2(12):100217. do

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available since

Dec. 1, 2022

Availability

Academic Institutions and Nonprofits only
pC004 - PFS library in Beta-lactamase gene Target Plasmid

Pooled Library

#79153

Purpose

PFS library inserted at the 5' of the Beta-lactamase gene for screening PFS preference

Depositor

Feng Zhang

Article

Abudayyeh et al Science. 2016 Jun 2. pii: aaf5573.

Available since

Oct. 26, 2017

Availability

Academic Institutions and Nonprofits only
Human SLC SAM Library

Pooled Library

#132561

Purpose

Expresses gRNAs for activation of human Solute Carrier family genes

Depositor

Giulio Superti-Furga

Article

Rebsamen et al Life Sci Alliance. 2022 Sep 16;5(11):e20

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

May 18, 2020

Availability

Academic Institutions and Nonprofits only
PB-EF1a-Puro-V8.2

Pooled Library

#178943

Purpose

Barcoding library for the macsGESTALT inducible lineage recording system

Depositor

Christopher Lengner

Article

Simeonov et al Cancer Cell. 2021 Aug 9;39(8):1150-1162.

Expression

Mammalian

Available since

March 22, 2022

Availability

Academic Institutions and Nonprofits only
Mouse sphingolipid metabolism knockout library

Pooled Library

#206249

Purpose

The sphingolipid metabolism library targets 82 mouse genes in the de novo ceramide and downstream sphingolipid metabolism pathways.

Depositor

Kivanc Birsoy

Article

Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

Use

CRISPR and Lentiviral

Available since

Aug. 29, 2024

Availability

Academic Institutions and Nonprofits only
Ma-PylRS-lib1

Pooled Library

#224585

Purpose

Pyrrolysine tRNA synthetase library to generate new genetic code expansion (GCE) systems for site-specific incorporation of non-canonical amino acids (ncAAs) into proteins.

Depositor

Ryan Mehl

Article

Avila-Crump et al ACS Chem Biol. 2022 Dec 16;17(12):3458-3

Expression

Bacterial

Species

Methanomethylophilus alvus

Available since

Jan. 6, 2025

Availability

Academic Institutions and Nonprofits only
Human CRISPRi sgRNA library Dolcetto in backbone XPR_050, Set A

Pooled Library

#92385

Purpose

Crispri

Depositor

John Doench, David Root

Article

Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

Has Service

Lentiviral Prep

Use

Lentiviral

Available since

July 13, 2018

Availability

Academic Institutions and Nonprofits only
Mouse CRISPRi sgRNA library Dolomiti in backbone XPR_050, Set A

Pooled Library

#104090

Purpose

Crispri

Depositor

John Doench, David Root

Article

Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

Use

Lentiviral

Available since

July 13, 2018

Availability

Academic Institutions and Nonprofits only
Human CRISPRi sgRNA library Dolcetto in backbone XPR_050, Set B

Pooled Library

#92386

Purpose

Crispri

Depositor

John Doench, David Root

Article

Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

Use

Lentiviral

Available since

July 13, 2018

Availability

Academic Institutions and Nonprofits only
Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set B

Pooled Library

#92380

Purpose

CRISPRa

Depositor

John Doench, David Root

Article

Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

Use

Lentiviral

Available since

Aug. 3, 2017

Availability

Academic Institutions and Nonprofits only

Showing: 1 - 20 of 42 results

Results per page:

Sort results by:

Yeast Inducible CRISPRi Library

Membrane protein gRNA library

Human ubiquitination-related proteins CRISPR KO library

Human Transporter Knockout library

StopPR epegRNA library (lAC002)

pRep-Cap Scanning Saturation Mutagenesis (SSM) pooled library

Self-targeting epegRNA library, +5 G>H (lDS004)

Self-targeting epegRNA library, Tiled edits (lRM001)

Splicing-targeting CRISPR-Cas9 library for human lncRNAs

MYC-CRISPR

Mouse Liver CRISPR Knockout Library

pC004 - PFS library in Beta-lactamase gene Target Plasmid

Human SLC SAM Library

PB-EF1a-Puro-V8.2

Mouse sphingolipid metabolism knockout library

Ma-PylRS-lib1

Human CRISPRi sgRNA library Dolcetto in backbone XPR_050, Set A

Mouse CRISPRi sgRNA library Dolomiti in backbone XPR_050, Set A

Human CRISPRi sgRNA library Dolcetto in backbone XPR_050, Set B

Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set B

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