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Showing: 101 - 120 of 146 results

  3. Pan-Druggable Cancer Library

    Pooled Library
    #182133
    Purpose
    All-in-one CRISPR/Cas system with 74 individual elements. 63 elements target cancer-related genes with FDA-approved drug treatments, and 3 elements target key medulloblastoma driver genes.
    Depositor
    Prashant Mali
    Article
    Hu et al Biomaterials. 2022 Jan;280:121276. doi:
    Species
    Homo sapiens
    Use
    CRISPR and Lentiviral
    Available since
    Aug. 26, 2022
    Availability
    Academic Institutions and Nonprofits only

  6. pLCKO2::TKOv3

    Pooled Library
    #125517
    Purpose
    Human CRISPR lentiviral library containing 70,948 guides (4-5 guides/gene) targeting 18,053 human protein-coding genes, in a non-Cas9 containing backbone
    Depositor
    Jason Moffat
    Article
    Mair et al Cell Rep. 2019 Apr 9;27(2):599-615.e12.
    Expression
    Mammalian
    Species
    Homo sapiens
    Use
    CRISPR and Lentiviral
    Available since
    Aug. 1, 2019
    Availability
    Academic Institutions and Nonprofits only

  10. EFS-mTSG

    Pooled Library
    #113584
    Purpose
    AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes
    Depositor
    Sidi Chen
    Article
    Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:
    Expression
    Mammalian
    Use
    AAV, CRISPR, Lentiviral, and Luciferase
    Available since
    July 23, 2019
    Availability
    Academic Institutions and Nonprofits only

  11. TBG-mTSG

    Pooled Library
    #113585
    Purpose
    AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes in mouse liver
    Depositor
    Sidi Chen
    Article
    Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:
    Expression
    Mammalian
    Use
    AAV, CRISPR, Lentiviral, and Luciferase
    Available since
    July 23, 2019
    Availability
    Academic Institutions and Nonprofits only

  12. pRG01-MCAP_MET

    Pooled Library
    #123361
    Purpose
    pRG01 with barcoded MCAP_Met crRNA array library cloned in, targeting combinations of metastasis drivers.
    Depositor
    Sidi Chen
    Article
    Chow et al Nat Methods. 2019 May;16(5):405-408. doi
    Expression
    Mammalian
    Species
    Synthetic
    Use
    CRISPR and Lentiviral
    Available since
    June 10, 2019
    Availability
    Academic Institutions and Nonprofits only

  14. MinLibCas9

    Pooled Library
    #164896
    Purpose
    Human genome-wide CRISPR-Cas9 gRNA library, optimised by mining existing large-scale screening datasets, which provides a >60% reduction in size while preserving key information content
    Depositor
    Mathew Garnett
    Article
    Gonçalves et al Genome Biol. 2021 Jan 21;22(1):40. doi:
    Expression
    Mammalian
    Species
    Homo sapiens
    Use
    CRISPR and Lentiviral
    Available since
    May 20, 2021
    Availability
    Academic Institutions and Nonprofits only

  15. Human Genome-Wide Reduced Double-gRNA library

    Pooled Library
    #137999
    Purpose
    This gRNA library targets the human coding genome, aimed to reduce the scale of genome-wide perturbation screens up to fivefold compared to conventional methods, without sacrificing performance.
    Depositor
    Leopold Parts
    Article
    Peets et al bioRxiv 859652
    Species
    Homo sapiens
    Use
    CRISPR and Lentiviral
    Available since
    Oct. 15, 2020
    Availability
    Academic Institutions and Nonprofits only
Showing: 101 - 120 of 146 results