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Mouse sgRNA library Brie in lentiGuide-Puro

Pooled Library

#73633

Purpose

Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Feb. 25, 2016

Availability

Academic Institutions and Nonprofits only
Toronto KnockOut version 3 library (TKOv3)

Pooled Library

#90294

Purpose

Optimized library offering improved accuracy, efficiency, and scalability for CRISPR screens compared to TKOv1

Depositor

Jason Moffat

Article

Hart et al G3 (Bethesda). 2017 Aug 7;7(8):2719-2727

Available since

May 5, 2017

Availability

Academic Institutions and Nonprofits only
Human ubiquitination-related proteins CRISPR KO library

Pooled Library

#174592

Purpose

CRISPR Cas9 KO library targets 660 ubiquitination-related proteins, including all major E1, E2, E3 and deubiquitinating enzymes, as well as other ubiquitination-related proteins.

Depositor

Juan Bonifacino

Article

Jia et al Elife. 2019 Nov 6;8. pii: 50034. doi: 10

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Nov. 30, 2021

Availability

Academic Institutions and Nonprofits only
Human GeCKO Lentiviral sgRNA Library v2 (lentiGuide-Puro)

Pooled Library

#1000000049

Purpose

CRISPR gRNA knockout pooled library for targeting the human genome

Depositor

Feng Zhang

Available since

May 8, 2014

Availability

Academic Institutions and Nonprofits only
The Human Druggable CRISPR library

Pooled Library

#200013

Purpose

The library contains ~10,000 sgRNAs targeting 1,980 human genes (5 sgRNAs per gene and 100 nontargeting control sgRNAs).

Depositor

Lianxin Liu

Article

Zheng et al Adv Sci (Weinh). 2023 Aug;10(22):e220679

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

May 9, 2023

Availability

Academic Institutions and Nonprofits only
LARRYv2-T-Sapphire library 1

Pooled Library

#233213

Purpose

Barcoding pooled library

Depositor

Alejo Rodriguez-Fraticelli

Article

Singh et al Cell Stem Cell. 2025 Feb 19:S1934-5909(2

Species

Synthetic

Use

Lentiviral

Available since

March 6, 2025

Availability

Academic Institutions and Nonprofits only
Human SAM library in lentiSAMv2 backbone

Pooled Library

#1000000078

Purpose

Genome-wide CRISPR gRNA pooled library for activation of human genes

Depositor

Feng Zhang

Available since

June 27, 2016

Availability

Academic Institutions and Nonprofits only
Glycogene CRISPR Library

Pooled Library

#140961

Purpose

Targets human genes involved in cellular glycosylation.

Depositor

Sriram Neelamegham

Article

Zhu et al Glycobiology. 2020 Aug 8. pii: 5889976.

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Sept. 9, 2020

Availability

Academic Institutions and Nonprofits only
Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned1

Pooled Library

#101932

Purpose

Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned1. Coexpresses mCherry.

Depositor

Michael Bassik

Article

Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

Expression

Mammalian

Use

CRISPR

Available since

May 23, 2018

Availability

Academic Institutions and Nonprofits only
ACER

Pooled Library

#226117

Purpose

The Advanced Catalogue of Epigenetic Regulators (ACER) library allows scientists to study how different epigenetic proteins influence gene activity and contribute to diseases.

Depositor

Rui Lu

Article

Zhou et al Blood. 2024 Aug 16:blood.2023023644. doi

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Oct. 29, 2024

Availability

Academic Institutions and Nonprofits only
DDR_MKOv4

Pooled Library

#140219

Purpose

CRISPR DNA damage response library

Depositor

Junjie Chen

Article

Su et al DNA Repair (Amst). 2020 Jan 16;87:102803

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Aug. 20, 2021

Availability

Academic Institutions and Nonprofits only
PB-EF1a-Puro-V8.2

Pooled Library

#178943

Purpose

Barcoding library for the macsGESTALT inducible lineage recording system

Depositor

Christopher Lengner

Article

Simeonov et al Cancer Cell. 2021 Aug 9;39(8):1150-1162.

Expression

Mammalian

Available since

March 22, 2022

Availability

Academic Institutions and Nonprofits only
Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF)

Pooled Library

#1000000111

Purpose

Genome-wide CRISPR gRNA pooled library for activation of human genes

Depositor

John Doench, David Root

Available since

Aug. 3, 2017

Availability

Academic Institutions and Nonprofits only
Human Brunello kinome pooled library, guides 1-8 in lentiCRISPRv2 backbone

Pooled Library

#1000000083

Purpose

CRISPR gRNA knockout pooled library for targeting the human kinome

Depositor

John Doench, David Root

Available since

June 27, 2016

Availability

Academic Institutions and Nonprofits only
Mini-human AsCpf1-based human genome-wide knockout library

Pooled Library

#130630

Purpose

Expresses crRNAs for genome-wide knockout pooled library screening

Depositor

Giulio Draetta

Article

Liu et al Nat Commun. 2019 Jul 17;10(1):3144. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Sept. 9, 2019

Availability

Academic Institutions and Nonprofits only
Human CRISPRi sgRNA library Dolcetto in backbone XPR_050

Pooled Library

#1000000114

Purpose

Genome-wide CRISPR gRNA pooled library for inhibition of human genes

Depositor

John Doench, David Root

Available since

July 13, 2018

Availability

Academic Institutions and Nonprofits only
Human Lipid Droplet and Metabolism Library

Pooled Library

#191535

Purpose

Lentiviral CRISPR library targeting 1,196 genes related to lipid droplet biology and cell metabolism.

Depositor

James Olzmann

Article

Roberts et al Dev Cell. 2023 Jul 18:S1534-5807(23)0033

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

March 1, 2023

Availability

Academic Institutions and Nonprofits only
LARRYv2-EGFP library 2

Pooled Library

#233216

Purpose

Barcoding pooled library

Depositor

Alejo Rodriguez-Fraticelli

Article

Singh et al Cell Stem Cell. 2025 Feb 19:S1934-5909(2

Species

Synthetic

Use

Lentiviral

Available since

March 6, 2025

Availability

Academic Institutions and Nonprofits only
LARRYv2-T-Sapphire library 2

Pooled Library

#233214

Purpose

Barcoding pooled library

Depositor

Alejo Rodriguez-Fraticelli

Article

Singh et al Cell Stem Cell. 2025 Feb 19:S1934-5909(2

Species

Synthetic

Use

Lentiviral

Available since

March 6, 2025

Availability

Academic Institutions and Nonprofits only
Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF)

Pooled Library

#1000000113

Purpose

Genome-wide CRISPR gRNA pooled library for activation of mouse genes

Depositor

John Doench, David Root

Available since

July 13, 2018

Availability

Academic Institutions and Nonprofits only

Showing: 41 - 60 of 370 results

Results per page:

Sort results by:

Mouse sgRNA library Brie in lentiGuide-Puro

Toronto KnockOut version 3 library (TKOv3)

Human ubiquitination-related proteins CRISPR KO library

Human GeCKO Lentiviral sgRNA Library v2 (lentiGuide-Puro)

The Human Druggable CRISPR library

LARRYv2-T-Sapphire library 1

Human SAM library in lentiSAMv2 backbone

Glycogene CRISPR Library

Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned1

ACER

DDR_MKOv4

PB-EF1a-Puro-V8.2

Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF)

Human Brunello kinome pooled library, guides 1-8 in lentiCRISPRv2 backbone

Mini-human AsCpf1-based human genome-wide knockout library

Human CRISPRi sgRNA library Dolcetto in backbone XPR_050

Human Lipid Droplet and Metabolism Library

LARRYv2-EGFP library 2

LARRYv2-T-Sapphire library 2

Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF)

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