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Human SLC KO Library

Pooled Library

#132552

Purpose

Expresses gRNAs for knockout of the human Solute Carrier family

Depositor

Giulio Superti-Furga

Article

Girardi et al Nat Chem Biol. 2020 Apr;16(4):469-478. d

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

May 7, 2020

Availability

Academic Institutions and Nonprofits only
RNA-binding protein pooled CRISPR knockout library

Pooled Library

#141438

Purpose

CRISPR knockout library targets RBPs with 10 sgRNAs/gene

Depositor

Eugene Yeo

Article

Wheeler et al Nat Methods. 2020 May 11. pii: 10.1038/s

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

May 28, 2020

Availability

Academic Institutions and Nonprofits only
Humagne Set C

Pooled Library

#172650

Purpose

Set C contains best-ranked guides 1 and 4.

Depositor

David Root, John Doench

Article

DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

Expression

Mammalian

Available since

Nov. 10, 2021

Availability

Academic Institutions and Nonprofits only
Humagne Set D

Pooled Library

#172651

Purpose

Set D contains best-ranked guides 2 and 3.

Depositor

David Root, John Doench

Article

DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

Expression

Mammalian

Available since

Nov. 10, 2021

Availability

Academic Institutions and Nonprofits only
MORF library without GFP and mCherry controls

Pooled Library

#192821

Purpose

Barcoded transcription factor ORF library for high throughput screening

Depositor

Feng Zhang

Article

Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

Expression

Mammalian

Species

Homo sapiens

Use

Lentiviral

Available since

Jan. 11, 2023

Availability

Academic Institutions and Nonprofits only
SARS-CoV-2 Spike (S) Ectodomain Library C

Pooled Library

#157973

Purpose

Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

Depositor

Timothy Whitehead

Article

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Expression

Bacterial and Yeast

Species

Sars-cov-2

Available since

Sept. 13, 2021

Availability

Academic Institutions and Nonprofits only
SARS-CoV-2 Spike (S) Ectodomain Library B

Pooled Library

#157972

Purpose

Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

Depositor

Timothy Whitehead

Article

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Expression

Bacterial and Yeast

Species

Sars-cov-2

Available since

Sept. 13, 2021

Availability

Academic Institutions and Nonprofits only
SARS-CoV-2 Spike (S) Ectodomain Library A

Pooled Library

#157971

Purpose

Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

Depositor

Timothy Whitehead

Article

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Expression

Bacterial and Yeast

Species

Sars-cov-2

Available since

Sept. 13, 2021

Availability

Academic Institutions and Nonprofits only
BLaER1 pgRNA CRISPR library

Pooled Library

#183825

Purpose

CRISPR-Cas9 library to target lncRNAs and protein coding genes with a potential role in B-cell to macrophage transdifferentiation.

Depositor

Roderic Guigo

Article

Arnan et al BMC Genomics. 2022 May 26;23(1):402. doi

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Aug. 25, 2022

Availability

Academic Institutions and Nonprofits only
SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library 1

Pooled Library

#168776

Purpose

Pooled library expressing barcoded SARS-CoV-2 RNA Binding Domain mutations

Depositor

Timothy Whitehead

Article

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Expression

Yeast

Species

Sars-cov-2

Available since

Sept. 13, 2021

Availability

Academic Institutions and Nonprofits only
SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library 2

Pooled Library

#168777

Purpose

Pooled library expressing barcoded SARS-CoV-2 RNA Binding Domain mutations

Depositor

Timothy Whitehead

Article

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Expression

Yeast

Species

Sars-cov-2

Available since

Sept. 13, 2021

Availability

Academic Institutions and Nonprofits only
SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library N501Y Tile 2 (positions 437-527)

Pooled Library

#174296

Purpose

This library contains mutations to SARS-CoV-2 Spike RBD N501Y variant in which all surface exposed residues on S RBD (Tile 2, positions 437-527) were mutated to every other amino acid.

Depositor

Timothy Whitehead

Article

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Expression

Yeast

Available since

Sept. 13, 2021

Availability

Academic Institutions and Nonprofits only
SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library N501Y Tile 1 (positions 333-436)

Pooled Library

#174295

Purpose

This library contains mutations to SARS-CoV-2 Spike RBD N501Y variant in which all surface exposed residues on S RBD (Tile 1, positions 333-436) were mutated to every other amino acid.

Depositor

Timothy Whitehead

Article

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Expression

Yeast

Available since

Sept. 13, 2021

Availability

Academic Institutions and Nonprofits only
SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library E484K Tile 2 (positions 437-527)

Pooled Library

#174294

Purpose

This library contains mutations to SARS-CoV-2 Spike RBD E484K variant in which all surface exposed residues on S RBD (Tile 2, positions 437-527) were mutated to every other amino acid.

Depositor

Timothy Whitehead

Article

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Expression

Yeast

Available since

Sept. 13, 2021

Availability

Academic Institutions and Nonprofits only
SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library E484K Tile 1 (positions 333-436)

Pooled Library

#174293

Purpose

This library contains mutations to SARS-CoV-2 Spike RBD E484K variant in which all surface exposed residues on S RBD (Tile 1, positions 333-436) were mutated to every other amino acid.

Depositor

Timothy Whitehead

Article

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Expression

Yeast

Available since

Sept. 13, 2021

Availability

Academic Institutions and Nonprofits only
pCMV-Rep78/68 Scanning Saturation Mutagenesis (SSM)

Pooled Library

#198050

Purpose

By supplying an AAV cap gene of interest in trans, researchers can use this library to investigate the effects of rep mutations on production of a wide range of AAV capsid serotypes

Depositor

George Church

Article

Jain et al bioRxiv 2023.01.31.526541

Expression

Mammalian

Use

AAV

Available since

May 4, 2023

Availability

Academic Institutions and Nonprofits only
Human CRISPR Metabolic Gene Knockout Library

Pooled Library

#110066

Purpose

Encodes gRNAs for targeting metabolic genes in CRISPR screens.

Depositor

David Sabatini

Article

Birsoy et al Cell. 2015 Jul 30;162(3):540-51. doi: 10

Use

Lentiviral

Available since

May 4, 2018

Availability

Academic Institutions and Nonprofits only
Human CRISPRi sgRNA library Dolcetto in backbone XPR_050, Set A

Pooled Library

#92385

Purpose

Crispri

Depositor

David Root, John Doench

Article

Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

Has Service

Lentiviral Prep

Use

Lentiviral

Available since

July 13, 2018

Availability

Academic Institutions and Nonprofits only
Human sgRNA library Gattinara in pRDA_118 backbone

Pooled Library

#136986

Purpose

Expresses sgRNAs targeting human genes

Depositor

John Doench

Article

DeWeirdt et al Nat Commun. 2020 Feb 6;11(1):752. doi: 1

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Feb. 24, 2020

Availability

Academic Institutions and Nonprofits only
Mouse sgRNA library Gouda in pRDA_118 backbone

Pooled Library

#136987

Purpose

Expresses sgRNAs targeting mouse genes

Depositor

John Doench

Article

DeWeirdt et al Nat Commun. 2020 Feb 6;11(1):752. doi: 1

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available since

Feb. 24, 2020

Availability

Academic Institutions and Nonprofits only

Showing: 21 - 40 of 91 results

Results per page:

Sort results by:

Human SLC KO Library

RNA-binding protein pooled CRISPR knockout library

Humagne Set C

Humagne Set D

MORF library without GFP and mCherry controls

SARS-CoV-2 Spike (S) Ectodomain Library C

SARS-CoV-2 Spike (S) Ectodomain Library B

SARS-CoV-2 Spike (S) Ectodomain Library A

BLaER1 pgRNA CRISPR library

SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library 1

SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library 2

SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library N501Y Tile 2 (positions 437-527)

SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library N501Y Tile 1 (positions 333-436)

SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library E484K Tile 2 (positions 437-527)

SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library E484K Tile 1 (positions 333-436)

pCMV-Rep78/68 Scanning Saturation Mutagenesis (SSM)

Human CRISPR Metabolic Gene Knockout Library

Human CRISPRi sgRNA library Dolcetto in backbone XPR_050, Set A

Human sgRNA library Gattinara in pRDA_118 backbone

Mouse sgRNA library Gouda in pRDA_118 backbone

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