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MORF library without GFP and mCherry controls

Pooled Library

#192821

Purpose

Barcoded transcription factor ORF library for high throughput screening

Depositor

Feng Zhang

Article

Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

Expression

Mammalian

Species

Homo sapiens

Use

Lentiviral

Available since

Jan. 11, 2023

Availability

Academic Institutions and Nonprofits only
The Human Druggable CRISPR library

Pooled Library

#200013

Purpose

The library contains ~10,000 sgRNAs targeting 1,980 human genes (5 sgRNAs per gene and 100 nontargeting control sgRNAs).

Depositor

Lianxin Liu

Article

Zheng et al Adv Sci (Weinh). 2023 Aug;10(22):e220679

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

May 9, 2023

Availability

Academic Institutions and Nonprofits only
S. rosetta Col- cDNA amplified library

Pooled Library

#62843

Purpose

amplified library of Salpingoeca rosetta

Depositor

Nicole King

Article

Fairclough et al Genome Biol. 2013 Feb 18;14(2):R15. doi:

Expression

Bacterial

Species

Salpingoeca rosetta

Available since

June 16, 2015

Availability

Academic Institutions and Nonprofits only
S. rosetta Col+ cDNA amplified library

Pooled Library

#62844

Purpose

amplified library of Salpingoeca rosetta from a colony rich culture which included the colony inducing bacteria Algoriphagus machipongonensis

Depositor

Nicole King

Article

Fairclough et al Genome Biol. 2013 Feb 18;14(2):R15. doi:

Expression

Bacterial

Species

Salpingoeca rosetta

Available since

June 16, 2015

Availability

Academic Institutions and Nonprofits only
Barcode Library 1 (BCL1)

Pooled Library

#179852

Purpose

Lentiviral barcode library that consists of 10^6 unique barcodes. Barcodes consist of 12bp degenerate region followed by two stable bases (C or G) and 4bp unique library code CCAA.

Depositor

Jason Moffat

Article

Rehman et al Cell. 2021 Jan 7;184(1):226-242.e21. doi

Expression

Mammalian

Use

Lentiviral

Available since

May 12, 2022

Availability

Academic Institutions and Nonprofits only
Barcode Library 0 (BCL0)

Pooled Library

#179851

Purpose

Lentiviral barcode library that consists of 10^6 unique barcodes. Barcodes consist of 12bp degenerate region followed by two stable bases (C or G) and 4bp unique library code ACGT.

Depositor

Jason Moffat

Article

Rehman et al Cell. 2021 Jan 7;184(1):226-242.e21. doi

Expression

Mammalian

Use

Lentiviral

Available since

May 12, 2022

Availability

Academic Institutions and Nonprofits only
Mouse Liver CRISPR Knockout Library

Pooled Library

#192824

Purpose

CRISPR screening library containing ~72,000 sgRNAs

Depositor

Kristin Knouse

Article

Keys et al Cell Genom. 2022 Dec 14;2(12):100217. do

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available since

Dec. 1, 2022

Availability

Academic Institutions and Nonprofits only
TRE-MPRA_minCMV Library

Pooled Library

#201012

Purpose

Massively parallel reporter assay (MPRA) library with minCMV promoter

Depositor

Justin English

Article

Zahm et al bioRxiv. 2023 May 11:2023.05.11.539703.

Expression

Mammalian

Use

Luciferase

Available since

Oct. 31, 2023

Availability

Academic Institutions and Nonprofits only
lentiCRISPRv2_ISG

Pooled Library

#125753

Purpose

Expresses gRNAs targeting human Interferon-Stimulated Genes

Depositor

Michael Emerman, Molly OhAinle

Article

Roesch et al Retrovirology. 2018 Mar 20;15(1):26. doi

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

May 7, 2020

Availability

Academic Institutions and Nonprofits only
TRE-MPRA_minTK Library

Pooled Library

#201014

Purpose

Massively parallel reporter assay (MPRA) library with minTK promoter

Depositor

Justin English

Article

Zahm et al bioRxiv. 2023 May 11:2023.05.11.539703.

Expression

Mammalian

Use

Luciferase

Available since

Oct. 31, 2023

Availability

Academic Institutions and Nonprofits only
TRE-MPRA_minPromega Library

Pooled Library

#201013

Purpose

Massively parallel reporter assay (MPRA) library with minPromega promoter

Depositor

Justin English

Article

Zahm et al bioRxiv. 2023 May 11:2023.05.11.539703.

Expression

Mammalian

Use

Luciferase

Available since

Oct. 31, 2023

Availability

Academic Institutions and Nonprofits only
pC004 - PFS library in Beta-lactamase gene Target Plasmid

Pooled Library

#79153

Purpose

PFS library inserted at the 5' of the Beta-lactamase gene for screening PFS preference

Depositor

Feng Zhang

Article

Abudayyeh et al Science. 2016 Jun 2. pii: aaf5573.

Available since

Oct. 26, 2017

Availability

Academic Institutions and Nonprofits only
DNA repair library with 1,573 sgRNAs

Pooled Library

#177663

Purpose

CRISPR-interference (CRISPRi) library of 1,573 sgRNAs targeting 476 genes encoding factors involved in DNA repair and associated processes

Depositor

Brittany Adamson

Article

Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

Species

Homo sapiens

Use

CRISPR

Available since

July 11, 2023

Availability

Academic Institutions and Nonprofits only
EFS-mTSG

Pooled Library

#113584

Purpose

AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes

Depositor

Sidi Chen

Article

Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

Expression

Mammalian

Use

AAV, CRISPR, Lentiviral, and Luciferase

Available since

July 23, 2019

Availability

Academic Institutions and Nonprofits only
DNA repair library with 336 sgRNAs

Pooled Library

#177664

Purpose

CRISPR-interference (CRISPRi) library of 366 sgRNAs targeting 118 genes encoding factors involved in DNA repair and associated processes

Depositor

Brittany Adamson

Article

Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

Species

Homo sapiens

Use

CRISPR

Available since

Nov. 29, 2023

Availability

Academic Institutions and Nonprofits only
TBG-mTSG

Pooled Library

#113585

Purpose

AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes in mouse liver

Depositor

Sidi Chen

Article

Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

Expression

Mammalian

Use

AAV, CRISPR, Lentiviral, and Luciferase

Available since

July 23, 2019

Availability

Academic Institutions and Nonprofits only
ACER

Pooled Library

#226117

Purpose

The Advanced Catalogue of Epigenetic Regulators (ACER) library allows scientists to study how different epigenetic proteins influence gene activity and contribute to diseases.

Depositor

Rui Lu

Article

Zhou et al Blood. 2024 Aug 16:blood.2023023644. doi

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Oct. 29, 2024

Availability

Academic Institutions and Nonprofits only
DNA repair library with 1,513 sgRNAs

Pooled Library

#177670

Purpose

CRISPR-interference (CRISPRi) library designed to target 476 genes involved in DNA repair and associated processes. It contains 1,513 sgRNAs and 60 non-targeting control sgRNAs.

Depositor

Brittany Adamson

Article

Chen et al Cell. 2021 Oct 28;184(22):5635-5652.e29.

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

July 11, 2023

Availability

Academic Institutions and Nonprofits only
CHyMErA LbCas12a Nuclease Optimization hgRNA Library

Pooled Library

#209734

Purpose

CHyMErA Cas12a Nuclease Optimization hgRNA Libraries allows assessment and comparison of the efficacy of different LbCas12a nucleases in the context of the Cas9-Cas12a CHyMErA system.

Depositor

Thomas Gonatopoulos-Pournatzis

Article

Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

June 20, 2024

Availability

Academic Institutions and Nonprofits only
CHyMErA AsCas12a Nuclease Optimization hgRNA Library

Pooled Library

#209735

Purpose

CHyMErA Cas12a Nuclease Optimization hgRNA Libraries allows assessment and comparison of the efficacy of different AsCas12a nucleases in the context of the Cas9-Cas12a CHyMErA system.

Depositor

Thomas Gonatopoulos-Pournatzis

Article

Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

June 20, 2024

Availability

Academic Institutions and Nonprofits only

Showing: 21 - 40 of 41 results

Results per page:

Sort results by:

MORF library without GFP and mCherry controls

The Human Druggable CRISPR library

S. rosetta Col- cDNA amplified library

S. rosetta Col+ cDNA amplified library

Barcode Library 1 (BCL1)

Barcode Library 0 (BCL0)

Mouse Liver CRISPR Knockout Library

TRE-MPRA_minCMV Library

lentiCRISPRv2_ISG

TRE-MPRA_minTK Library

TRE-MPRA_minPromega Library

pC004 - PFS library in Beta-lactamase gene Target Plasmid

DNA repair library with 1,573 sgRNAs

EFS-mTSG

DNA repair library with 336 sgRNAs

TBG-mTSG

ACER

DNA repair library with 1,513 sgRNAs

CHyMErA LbCas12a Nuclease Optimization hgRNA Library

CHyMErA AsCas12a Nuclease Optimization hgRNA Library

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