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Human GeCKO Lentiviral sgRNA Library v2 (LentiCRISPR)

Pooled Library

#1000000048

Purpose

CRISPR gRNA knockout pooled library for targeting the human genome

Depositor

Feng Zhang

Available since

May 8, 2014

Availability

Academic Institutions and Nonprofits only
SPLINTR mCHERRY v1

Pooled Library

#179775

Purpose

SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

Depositor

Mark Dawson

Article

Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

Expression

Mammalian

Use

Lentiviral

Available since

May 11, 2022

Availability

Academic Institutions and Nonprofits only
pSMAL-CellTag-multi-v1 barcode library

Pooled Library

#206045

Purpose

The CellTag multi library of barcodes can be used to clonally label cells with DNA barcodes. These barcodes can be profiled directly with single-cell RNA and ATAC sequencing, to allow clonal tracking

Depositor

Samantha Morris

Article

Jindal et al Nat Biotechnol. 2023 Sep 25. doi: 10.103

Use

Lentiviral

Available since

Nov. 2, 2023

Availability

Academic Institutions and Nonprofits only
Human SAM library in lentiSAMv2 backbone

Pooled Library

#1000000078

Purpose

Genome-wide CRISPR gRNA pooled library for activation of human genes

Depositor

Feng Zhang

Available since

June 27, 2016

Availability

Academic Institutions and Nonprofits only
LARRYv2-mScarlet library 1

Pooled Library

#233697

Purpose

Barcoding pooled library

Depositor

Alejo Rodriguez-Fraticelli

Article

Singh et al Cell Stem Cell. 2025 Feb 19:S1934-5909(2

Species

Synthetic

Use

Lentiviral

Available since

March 6, 2025

Availability

Academic Institutions and Nonprofits only
Ma-PylRS-lib1

Pooled Library

#224585

Purpose

Pyrrolysine tRNA synthetase library to generate new genetic code expansion (GCE) systems for site-specific incorporation of non-canonical amino acids (ncAAs) into proteins.

Depositor

Ryan Mehl

Article

Avila-Crump et al ACS Chem Biol. 2022 Dec 16;17(12):3458-3

Expression

Bacterial

Species

Methanomethylophilus alvus

Available since

Jan. 6, 2025

Availability

Academic Institutions and Nonprofits only
MORF library without GFP and mCherry controls

Pooled Library

#192821

Purpose

Barcoded transcription factor ORF library for high throughput screening

Depositor

Feng Zhang

Article

Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

Expression

Mammalian

Species

Homo sapiens

Use

Lentiviral

Available since

Jan. 11, 2023

Availability

Academic Institutions and Nonprofits only
Mouse Chromatin Regulator Library

Pooled Library

#200011

Purpose

CRISPR KO library targeting a comprehensive set of genes with annotated function as chromatin regulators.

Depositor

Bradley Bernstein, Robert Manguso, Gabriel Griffin

Article

Griffin et al Nature. 2021 Jul;595(7866):309-314. doi:

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Dec. 15, 2023

Availability

Academic Institutions and Nonprofits only
Human sgRNA library Brunello in lentiCRISPRv2

Pooled Library

#73179

Purpose

Human sgRNA library in backbone lentiCRISPRv2 targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Feb. 9, 2016

Availability

Academic Institutions and Nonprofits only
Human sgRNA library Brunello in lentiGuide-Puro

Pooled Library

#73178

Purpose

Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Feb. 9, 2016

Availability

Academic Institutions and Nonprofits only
Human CRISPR Metabolic Gene Knockout Library

Pooled Library

#110066

Purpose

Encodes gRNAs for targeting metabolic genes in CRISPR screens.

Depositor

David Sabatini

Article

Birsoy et al Cell. 2015 Jul 30;162(3):540-51. doi: 10

Use

Lentiviral

Available since

May 4, 2018

Availability

Academic Institutions and Nonprofits only
MORF Library Kit with GFP and mCherry controls

Pooled Library

#1000000218

Depositor

Feng Zhang

Available since

March 24, 2023

Availability

Academic Institutions and Nonprofits only
Membrane protein gRNA library

Pooled Library

#113345

Purpose

Contains 58,071 gRNAs targeting 6,213 membrane proteins and 500 non-targeting gRNAs

Depositor

Gavin Wright

Article

Chong et al Genome Biol. 2018 Nov 26;19(1):205. doi:

Species

Homo sapiens

Use

Lentiviral

Available since

Jan. 4, 2019

Availability

Academic Institutions and Nonprofits only
hCRISPRi-v2, genome-wide, top 5 sgRNAs/gene

Pooled Library

#83969

Purpose

Version 2 of the human CRISPRi genome wide library

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Use

Lentiviral

Available since

Nov. 15, 2016

Availability

Academic Institutions and Nonprofits only
Mouse sgRNA library Brie in lentiGuide-Puro

Pooled Library

#73633

Purpose

Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Feb. 25, 2016

Availability

Academic Institutions and Nonprofits only
Human Epigenetic Knockout Library

Pooled Library

#162256

Purpose

Lentiviral CRISPR library targets human epigenetic genes

Depositor

Kivanc Birsoy

Article

Williams et al Cell Metab. 2020 Apr 7;31(4):852-861.e6.

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Nov. 17, 2020

Availability

Academic Institutions and Nonprofits only
Bison sgRNA library

Pooled Library

#169942

Purpose

The BISON CRISPR library targets 713 E1, E2, and E3 ubiquitin ligases, deubiquitinases, and control genes and contains 2,852 guide RNAs. It was cloned into the pXPR003.

Depositor

Benjamin Ebert

Article

Slabicki et al Nature. 2020 Sep;585(7824):293-297. doi:

Use

Lentiviral

Available since

Sept. 9, 2021

Availability

Academic Institutions and Nonprofits only
Human Lipid Droplet and Metabolism Library

Pooled Library

#191535

Purpose

Lentiviral CRISPR library targeting 1,196 genes related to lipid droplet biology and cell metabolism.

Depositor

James Olzmann

Article

Roberts et al Dev Cell. 2023 Jul 18:S1534-5807(23)0033

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

March 1, 2023

Availability

Academic Institutions and Nonprofits only
Mouse Metabolism Library

Pooled Library

#163966

Purpose

Lentiviral CRISPR library targets 2,918 mouse metabolic genes with ~18,000 guide RNAs. The library contains ~6 gRNAs per gene.

Depositor

Alec Kimmelman

Article

Biancur et al Cell Metab. 2020 Oct 28. pii: S1550-4131

Use

CRISPR and Lentiviral

Available since

July 1, 2021

Availability

Academic Institutions and Nonprofits only
Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF)

Pooled Library

#1000000113

Purpose

Genome-wide CRISPR gRNA pooled library for activation of mouse genes

Depositor

David Root, John Doench

Available since

July 13, 2018

Availability

Academic Institutions and Nonprofits only

Showing: 1 - 20 of 370 results

Results per page:

Sort results by:

Human GeCKO Lentiviral sgRNA Library v2 (LentiCRISPR)

SPLINTR mCHERRY v1

pSMAL-CellTag-multi-v1 barcode library

Human SAM library in lentiSAMv2 backbone

LARRYv2-mScarlet library 1

Ma-PylRS-lib1

MORF library without GFP and mCherry controls

Mouse Chromatin Regulator Library

Human sgRNA library Brunello in lentiCRISPRv2

Human sgRNA library Brunello in lentiGuide-Puro

Human CRISPR Metabolic Gene Knockout Library

MORF Library Kit with GFP and mCherry controls

Membrane protein gRNA library

hCRISPRi-v2, genome-wide, top 5 sgRNAs/gene

Mouse sgRNA library Brie in lentiGuide-Puro

Human Epigenetic Knockout Library

Bison sgRNA library

Human Lipid Droplet and Metabolism Library

Mouse Metabolism Library

Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF)

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