380 results

1. Human sgRNA library Brunello in lentiGuide-Puro

   Pooled Library

   #73178

   Purpose

   Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Has Service

   Lentiviral Prep

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 9, 2016

   Availability

   Academic Institutions and Nonprofits only

2. Human Brunello kinome pooled library, guides 1-8 in lentiGuide-Puro backbone

   Pooled Library

   #1000000082

   Purpose

   CRISPR gRNA knockout pooled library for targeting the human kinome

   Depositor

   David Root, John Doench

   Available since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

3. Bison sgRNA library

   Pooled Library

   #169942

   Purpose

   The BISON CRISPR library targets 713 E1, E2, and E3 ubiquitin ligases, deubiquitinases, and control genes and contains 2,852 guide RNAs. It was cloned into the pXPR003.

   Depositor

   Benjamin Ebert

   Article

   Slabicki et al Nature. 2020 Sep;585(7824):293-297. doi:

   Use

   Lentiviral

   Available since

   Sept. 9, 2021

   Availability

   Academic Institutions and Nonprofits only

4. Human Brunello kinome pooled library, guides 1-8 in lentiCRISPRv2 backbone

   Pooled Library

   #1000000083

   Purpose

   CRISPR gRNA knockout pooled library for targeting the human kinome

   Depositor

   David Root, John Doench

   Available since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

5. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF)

   Pooled Library

   #1000000111

   Purpose

   Genome-wide CRISPR gRNA pooled library for activation of human genes

   Depositor

   David Root, John Doench

   Available since

   Aug. 3, 2017

   Availability

   Academic Institutions and Nonprofits only

6. Liu Lab MusCK (A + B)

   Pooled Library

   #1000000178

   Depositor

   Xiaole Shirley Liu

   Available since

   Oct. 29, 2021

   Availability

   Academic Institutions and Nonprofits only

7. Sabatini/Lander Lab Activity-Optimized Genome-wide Mouse sgRNA Library in pLenti-sgRNA

   Pooled Library

   #1000000096

   Purpose

   CRISPR gRNA knockout pooled library for targeting the mouse genome

   Depositor

   Eric Lander, David Sabatini

   Available since

   April 3, 2017

   Availability

   Academic Institutions and Nonprofits only

8. Human CRISPR Knockout Pooled Library (H3)

   Pooled Library

   #133914

   Purpose

   CRISPR gRNA knockout pooled library for targeting the human genome - version H3

   Depositor

   Myles Brown, Xiaole Shirley Liu

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Jan. 24, 2020

   Availability

   Academic Institutions and Nonprofits only

9. Sabatini/Lander Lab Activity-Optimized Genome-wide Human sgRNA Library in pLenti-sgRNA

   Pooled Library

   #1000000095

   Purpose

   CRISPR gRNA knockout pooled library for targeting the human genome

   Depositor

   Eric Lander, David Sabatini

   Available since

   April 3, 2017

   Availability

   Academic Institutions and Nonprofits only

10. DDR_MKOv4

    Pooled Library

    #140219

    Purpose

    CRISPR DNA damage response library

    Depositor

    Junjie Chen

    Article

    Su et al DNA Repair (Amst). 2020 Jan 16;87:102803

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Aug. 20, 2021

    Availability

    Academic Institutions and Nonprofits only

11. Cultivarium MACKEREL Library

    Pooled Library

    #208054

    Purpose

    pGL0_151 [RS421] is a library of broad host range prokaryotic promoters-RBS regulatory sequences formatted as a golden gate assembly Level 0 part.

    Depositor

    Nili Ostrov, Charlie Gilbert, Cultivarium Tools

    Article

    Gilbert et al bioRxiv 2024.02.23.581749

    Use

    Synthetic Biology

    Available since

    March 21, 2024

    Availability

    Academic Institutions and Nonprofits only

12. Human sgRNA library Brunello in lentiCRISPRv2

    Pooled Library

    #73179

    Purpose

    Human sgRNA library in backbone lentiCRISPRv2 targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Has Service

    Lentiviral Prep

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 9, 2016

    Availability

    Academic Institutions and Nonprofits only

13. Mouse CRISPRi sgRNA library Dolomiti in backbone XPR_050

    Pooled Library

    #1000000131

    Purpose

    Genome-wide CRISPR gRNA pooled library for inhibition of mouse genes

    Depositor

    David Root, John Doench

    Available since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

14. Membrane protein gRNA library

    Pooled Library

    #113345

    Purpose

    Contains 58,071 gRNAs targeting 6,213 membrane proteins and 500 non-targeting gRNAs

    Depositor

    Gavin Wright

    Article

    Chong et al Genome Biol. 2018 Nov 26;19(1):205. doi:

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    Jan. 4, 2019

    Availability

    Academic Institutions and Nonprofits only

15. Inzolia library in pRDA_052

    Pooled Library

    #209551

    Purpose

    The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

    Depositor

    John Doench

    Article

    Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

    Use

    CRISPR and Lentiviral

    Available since

    Dec. 5, 2023

    Availability

    Academic Institutions and Nonprofits only

16. TCR Rapid Assembly for Functional Testing (TCRAFT)

    Pooled Library

    #1000000264

    Depositor

    Michael Birnbaum

    Available since

    Aug. 12, 2025

    Availability

    Academic Institutions and Nonprofits only

17. The Human Druggable CRISPR library

    Pooled Library

    #200013

    Purpose

    The library contains ~10,000 sgRNAs targeting 1,980 human genes (5 sgRNAs per gene and 100 nontargeting control sgRNAs).

    Depositor

    Lianxin Liu

    Article

    Zheng et al Adv Sci (Weinh). 2023 Aug;10(22):e220679

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    May 9, 2023

    Availability

    Academic Institutions and Nonprofits only

18. MORF library without GFP and mCherry controls

    Pooled Library

    #192821

    Purpose

    Barcoded transcription factor ORF library for high throughput screening

    Depositor

    Feng Zhang

    Article

    Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    Jan. 11, 2023

    Availability

    Academic Institutions and Nonprofits only

19. Human CRISPR Metabolic Gene Knockout Library

    Pooled Library

    #110066

    Purpose

    Encodes gRNAs for targeting metabolic genes in CRISPR screens.

    Depositor

    David Sabatini

    Article

    Birsoy et al Cell. 2015 Jul 30;162(3):540-51. doi: 10

    Use

    Lentiviral

    Available since

    May 4, 2018

    Availability

    Academic Institutions and Nonprofits only

20. MORF Library Kit with GFP and mCherry controls

    Pooled Library

    #1000000218

    Depositor

    Feng Zhang

    Available since

    March 24, 2023

    Availability

    Academic Institutions and Nonprofits only