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363 results

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Human CRISPR Metabolic Gene Knockout Library

Pooled Library

#110066

Purpose

Encodes gRNAs for targeting metabolic genes in CRISPR screens.

Depositor

David Sabatini

Article

Birsoy et al Cell. 2015 Jul 30;162(3):540-51. doi: 10

Use

Lentiviral

Available since

May 4, 2018

Availability

Academic Institutions and Nonprofits only
hCRISPRa-v2, genome-wide, top 5 sgRNAs/gene

Pooled Library

#83978

Purpose

Version 2 of the human CRISPRa genome wide library

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Use

Lentiviral

Available since

Nov. 15, 2016

Availability

Academic Institutions and Nonprofits only
Human GeCKO Lentiviral sgRNA Library v2 (lentiGuide-Puro)

Pooled Library

#1000000049

Purpose

CRISPR gRNA knockout pooled library for targeting the human genome

Depositor

Feng Zhang

Available since

May 8, 2014

Availability

Academic Institutions and Nonprofits only
Human sgRNA library Brunello in lentiGuide-Puro

Pooled Library

#73178

Purpose

Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Feb. 9, 2016

Availability

Academic Institutions and Nonprofits only
hCRISPRi-v2, Gene Expression (h5), top 5 sgRNAs/gene

Pooled Library

#83975

Purpose

Human CRISPRi Pooled Library targeting gene expression

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Dec. 14, 2016

Availability

Academic Institutions and Nonprofits only
ACER

Pooled Library

#226117

Purpose

The Advanced Catalogue of Epigenetic Regulators (ACER) library allows scientists to study how different epigenetic proteins influence gene activity and contribute to diseases.

Depositor

Rui Lu

Article

Zhou et al Blood. 2024 Aug 16:blood.2023023644. doi

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Oct. 29, 2024

Availability

Academic Institutions and Nonprofits only
CRISPRi non-coding library (CRiNCL) - Unique to HEK293T

Pooled Library

#86543

Depositor

Jonathan Weissman

Article

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

Available since

March 8, 2017

Availability

Academic Institutions and Nonprofits only
Membrane protein gRNA library

Pooled Library

#113345

Purpose

Contains 58,071 gRNAs targeting 6,213 membrane proteins and 500 non-targeting gRNAs

Depositor

Gavin Wright

Article

Chong et al Genome Biol. 2018 Nov 26;19(1):205. doi:

Species

Homo sapiens

Use

Lentiviral

Available since

Jan. 4, 2019

Availability

Academic Institutions and Nonprofits only
Mouse sgRNA library Brie in lentiGuide-Puro

Pooled Library

#73633

Purpose

Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Feb. 25, 2016

Availability

Academic Institutions and Nonprofits only
Mouse sgRNA library Brie in lentiCRISPRv2

Pooled Library

#73632

Purpose

Mouse sgRNA library in backbone lentiCRISPRv2 containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Feb. 25, 2016

Availability

Academic Institutions and Nonprofits only
lentiCRISPRv2_ISG

Pooled Library

#125753

Purpose

Expresses gRNAs targeting human Interferon-Stimulated Genes

Depositor

Molly OhAinle, Michael Emerman

Article

Roesch et al Retrovirology. 2018 Mar 20;15(1):26. doi

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

May 7, 2020

Availability

Academic Institutions and Nonprofits only
hCRISPRi-v2, Kinases, Phosphatases, and Drug Targets (h1), top 5 sgRNAs/gene

Pooled Library

#83971

Purpose

Human CRISPRi Pooled Library tartgeting kinsases, phosphatases and Drug Targets

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Dec. 14, 2016

Availability

Academic Institutions and Nonprofits only
hCRISPRi-v2, Mitochondria, Trafficking, and Motility (h4), top 5 sgRNAs/gene

Pooled Library

#83974

Purpose

Human CRISPRi Pooled Library targeting Mitochondria, Trafficking, and Motility genes

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Dec. 14, 2016

Availability

Academic Institutions and Nonprofits only
Human sgRNA library Brunello in lentiCRISPRv2

Pooled Library

#73179

Purpose

Human sgRNA library in backbone lentiCRISPRv2 targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Feb. 9, 2016

Availability

Academic Institutions and Nonprofits only
Human Epigenetic Knockout Library

Pooled Library

#162256

Purpose

Lentiviral CRISPR library targets human epigenetic genes

Depositor

Kivanc Birsoy

Article

Williams et al Cell Metab. 2020 Apr 7;31(4):852-861.e6.

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Nov. 17, 2020

Availability

Academic Institutions and Nonprofits only
Human Cas13 Pooled Long-Noncoding RNA (lncRNA) Library

Pooled Library

#227014

Purpose

CRISPR-Cas13 lentiviral pooled library targeting human lncRNAs and their closest protein-coding genes for transcriptome-wide knockdown screens.

Depositor

Neville Sanjana

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Feb. 11, 2025

Availability

Academic Institutions and Nonprofits only
MORF Library Kit with GFP and mCherry controls

Pooled Library

#1000000218

Depositor

Feng Zhang

Available since

March 24, 2023

Availability

Academic Institutions and Nonprofits only
Mouse GeCKO Lentiviral sgRNA Library (LentiCRISPR)

Pooled Library

#1000000052

Purpose

CRISPR gRNA knockout pooled library for targeting the mouse genome

Depositor

Feng Zhang

Available since

July 23, 2014

Availability

Academic Institutions and Nonprofits only
MORF library without GFP and mCherry controls

Pooled Library

#192821

Purpose

Barcoded transcription factor ORF library for high throughput screening

Depositor

Feng Zhang

Article

Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

Expression

Mammalian

Species

Homo sapiens

Use

Lentiviral

Available since

Jan. 11, 2023

Availability

Academic Institutions and Nonprofits only
hCRISPRi-v2, genome-wide, top 5 sgRNAs/gene

Pooled Library

#83969

Purpose

Version 2 of the human CRISPRi genome wide library

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Use

Lentiviral

Available since

Nov. 15, 2016

Availability

Academic Institutions and Nonprofits only

Showing: 1 - 20 of 363 results

Results per page:

Sort results by:

Human CRISPR Metabolic Gene Knockout Library

hCRISPRa-v2, genome-wide, top 5 sgRNAs/gene

Human GeCKO Lentiviral sgRNA Library v2 (lentiGuide-Puro)

Human sgRNA library Brunello in lentiGuide-Puro

hCRISPRi-v2, Gene Expression (h5), top 5 sgRNAs/gene

ACER

CRISPRi non-coding library (CRiNCL) - Unique to HEK293T

Membrane protein gRNA library

Mouse sgRNA library Brie in lentiGuide-Puro

Mouse sgRNA library Brie in lentiCRISPRv2

lentiCRISPRv2_ISG

hCRISPRi-v2, Kinases, Phosphatases, and Drug Targets (h1), top 5 sgRNAs/gene

hCRISPRi-v2, Mitochondria, Trafficking, and Motility (h4), top 5 sgRNAs/gene

Human sgRNA library Brunello in lentiCRISPRv2

Human Epigenetic Knockout Library

Human Cas13 Pooled Long-Noncoding RNA (lncRNA) Library

MORF Library Kit with GFP and mCherry controls

Mouse GeCKO Lentiviral sgRNA Library (LentiCRISPR)

MORF library without GFP and mCherry controls

hCRISPRi-v2, genome-wide, top 5 sgRNAs/gene

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