382 results

1. Dual sgRNA CRISPRi Library

   Pooled Library

   #1000000192

   Depositor

   Jonathan Weissman

   Available Since

   Sept. 30, 2022

   Availability

   Academic Institutions and Nonprofits only

2. MORF Library Kit with GFP and mCherry controls

   Pooled Library

   #1000000218

   Depositor

   Feng Zhang

   Available Since

   March 24, 2023

   Availability

   Academic Institutions and Nonprofits only

3. Pan-cancer CasRx lncRNA Albarossa library

   Pooled Library

   #212966

   Purpose

   The human CasRx CRISPR lentiviral library encodes 75,725 gRNA arrays (two gRNAs per array) targeting 24,171 lncRNAs.

   Depositor

   Roland Rad

   Article

   Montero et al Nat Methods. 2024 Feb 26. doi: 10.1038/s

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 21, 2024

   Availability

   Academic Institutions and Nonprofits only

4. Dual sgRNA CRISPRa Library

   Pooled Library

   #1000000193

   Depositor

   Jonathan Weissman

   Available Since

   Sept. 30, 2022

   Availability

   Academic Institutions and Nonprofits only

5. Human CRISPR Knockout Pooled Library (H3)

   Pooled Library

   #133914

   Purpose

   CRISPR gRNA knockout pooled library for targeting the human genome - version H3

   Depositor

   Xiaole Shirley Liu, Myles Brown

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Jan. 24, 2020

   Availability

   Academic Institutions and Nonprofits only

6. p11-3’_8xN_PAM-site1 (RTW554)

   Pooled Library

   #160132

   Purpose

   Plasmid library harboring a randomized 8nt PAM 3’ of target site 1. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 3’ PAMs (e.g. Cas9)

   Depositor

   Keith Joung, Benjamin Kleinstiver

   Article

   Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

   Species

   Synthetic

   Use

   CRISPR

   Available Since

   Feb. 8, 2021

   Availability

   Academic Institutions and Nonprofits only

7. Human sgRNA library Brunello in lentiGuide-Puro

   Pooled Library

   #73178

   Purpose

   Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Has Service

   Lentiviral Prep

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 9, 2016

   Availability

   Academic Institutions and Nonprofits only

8. Human sgRNA library Brunello in lentiCRISPRv2

   Pooled Library

   #73179

   Purpose

   Human sgRNA library in backbone lentiCRISPRv2 targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Has Service

   Lentiviral Prep

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 9, 2016

   Availability

   Academic Institutions and Nonprofits only

9. Human GeCKO Lentiviral sgRNA Library v2 (LentiCRISPR)

   Pooled Library

   #1000000048

   Purpose

   CRISPR gRNA knockout pooled library for targeting the human genome

   Depositor

   Feng Zhang

   Available Since

   May 8, 2014

   Availability

   Academic Institutions and Nonprofits only

10. pMSCV-U6gRNA(lib)-PGKpuroT2ABFP library

    Pooled Library

    #104861

    Depositor

    Sarah Teichmann

    Article

    Henriksson et al Cell. 2019 Jan 7. pii: S0092-8674(18)315

    Available Since

    Sept. 9, 2019

    Availability

    Academic Institutions and Nonprofits only

11. Human CRISPRi sgRNA library Dolcetto in backbone XPR_050

    Pooled Library

    #1000000114

    Purpose

    Genome-wide CRISPR gRNA pooled library for inhibition of human genes

    Depositor

    John Doench, David Root

    Available Since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

12. Mouse sgRNA library Brie in lentiCRISPRv2

    Pooled Library

    #73632

    Purpose

    Mouse sgRNA library in backbone lentiCRISPRv2 containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    Feb. 25, 2016

    Availability

    Academic Institutions and Nonprofits only

13. Julianna (split-vector)

    Pooled Library

    #247028

    Purpose

    Mouse genome-wide CRISPR knockout library for the use of S. pyogenes Cas9. Each gene is targeted by 3 constructs.

    Depositor

    John Doench, David Root

    Article

    Drepanos et al bioRxiv 2025.08.26.672375; doi: https://

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available Since

    Oct. 2, 2025

    Availability

    Academic Institutions and Nonprofits only

14. Mouse sgRNA library Brie in lentiGuide-Puro

    Pooled Library

    #73633

    Purpose

    Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Has Service

    Lentiviral Prep

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    Feb. 25, 2016

    Availability

    Academic Institutions and Nonprofits only

15. Human Epigenetic Knockout Library

    Pooled Library

    #162256

    Purpose

    Lentiviral CRISPR library targets human epigenetic genes

    Depositor

    Kivanc Birsoy

    Article

    Williams et al Cell Metab. 2020 Apr 7;31(4):852-861.e6.

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Nov. 17, 2020

    Availability

    Academic Institutions and Nonprofits only

16. Human GeCKO Lentiviral sgRNA Library v2 (lentiGuide-Puro)

    Pooled Library

    #1000000049

    Purpose

    CRISPR gRNA knockout pooled library for targeting the human genome

    Depositor

    Feng Zhang

    Available Since

    May 8, 2014

    Availability

    Academic Institutions and Nonprofits only

17. MinLibCas9

    Pooled Library

    #164896

    Purpose

    Human genome-wide CRISPR-Cas9 gRNA library, optimised by mining existing large-scale screening datasets, which provides a >60% reduction in size while preserving key information content

    Depositor

    Mathew Garnett

    Article

    Gonçalves et al Genome Biol. 2021 Jan 21;22(1):40. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    May 20, 2021

    Availability

    Academic Institutions and Nonprofits only

18. Toronto KnockOut version 3 library (TKOv3)

    Pooled Library

    #90294

    Purpose

    Optimized library offering improved accuracy, efficiency, and scalability for CRISPR screens compared to TKOv1

    Depositor

    Jason Moffat

    Article

    Hart et al G3 (Bethesda). 2017 Aug 7;7(8):2719-2727

    Available Since

    May 5, 2017

    Availability

    Academic Institutions and Nonprofits only

19. pEPIP_PepTile_40merFragments_65CancerDrivers

    Pooled Library

    #172109

    Purpose

    Lentiviral peptide expression library for overexpression fitness screening

    Depositor

    Prashant Mali

    Article

    Ford et al Cell Syst. 2021 Jul 21;12(7):716-732.e7.

    Use

    Lentiviral

    Available Since

    Oct. 21, 2021

    Availability

    Academic Institutions and Nonprofits only

20. MORF library without GFP and mCherry controls

    Pooled Library

    #192821

    Purpose

    Barcoded transcription factor ORF library for high throughput screening

    Depositor

    Feng Zhang

    Article

    Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    Lentiviral

    Available Since

    Jan. 11, 2023

    Availability

    Academic Institutions and Nonprofits only