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Showing: 3401 - 3450 of 3976 results

  4. RMCE ABCDE>ala DNA-PKcs

    Plasmid
    #233914
    Purpose
    Low copy number provides expression of human DNA-PKcs with the 6 ABCDE phosphorylation sites substituted to alanine.
    Depositor
    Katheryn Meek
    Article
    Buehl et al Mol Cell. 2023 Mar 2;83(5):698-714.e4. d
    Insert
    human DNA-PKcs ABCDE phosphorylation site mutant (PRKDC Human)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    phosphorylation sites 2609, 2612, 2620, 2624, 263…
    Promoter
    Available since
    April 9, 2025
    Availability
    Academic Institutions and Nonprofits only
    233914-plasmid-map-sequence-id-468237

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  5. Anti-Kv2.1 K+ channel [K89/34R-rat IgG2a]

    Plasmid
    #225417
    Purpose
    Mammalian Expression Plasmid of anti-Kv2.1 K+ channel (Rat) rat IgG2a R-mAb. Derived from hybridoma K89/34.
    Depositor
    James Trimmer
    Article
    Andrews et al Elife. 2019 Jan 22;8. pii: 43322. doi: 1
    Insert
    Anti-Kv2.1 K+ channel (Rattus norvegicus) recombinant (Mouse) monoclonal antibody. (Kcnb1 Chimera: M. musculus (mouse)/R. norvegicus (rat))
    Use
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Dual CMV
    Available since
    Oct. 10, 2024
    Availability
    Academic Institutions and Nonprofits only
    225417-plasmid-map-sequence-id-448492

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  6. Anti-Kv4.2 K+ channel (external) [K57/1R-rat IgG2a]

    Plasmid
    #225419
    Purpose
    Mammalian Expression Plasmid of anti-Kv4.2 K+ channel (external) (Human) rat IgG2a R-mAb. Derived from hybridoma K57/1.
    Depositor
    James Trimmer
    Article
    Andrews et al Elife. 2019 Jan 22;8. pii: 43322. doi: 1
    Insert
    Anti-Kv4.2 K+ channel (external) (Homo sapiens) recombinant (Mouse) monoclonal antibody. (KCND2 Chimera: M. musculus (mouse)/R. norvegicus (rat))
    Use
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Dual CMV
    Available since
    Oct. 10, 2024
    Availability
    Academic Institutions and Nonprofits only
    225419-plasmid-map-sequence-id-448489

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  7. Anti-Mortalin [N52A/42R-rat IgG2a]

    Plasmid
    #225423
    Purpose
    Mammalian Expression Plasmid of anti-Mortalin (Mouse) rat IgG2a R-mAb. Derived from hybridoma N52A/42.
    Depositor
    James Trimmer
    Article
    Andrews et al Elife. 2019 Jan 22;8. pii: 43322. doi: 1
    Insert
    Anti-Mortalin (Mus musculus) recombinant (Mouse) monoclonal antibody. (Hspa9 Chimera: M. musculus (mouse)/R. norvegicus (rat))
    Use
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Dual CMV
    Available since
    Oct. 10, 2024
    Availability
    Academic Institutions and Nonprofits only
    225423-plasmid-map-sequence-id-448485

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  8. Anti-LRRK2/Dardarin, N-terminus [N138/6R]

    Plasmid
    #182104
    Purpose
    Mammalian Expression Plasmid of anti-LRRK2/Dardarin, N-terminus (Human). Derived from hybridoma N138/6.
    Depositor
    James Trimmer
    Article
    Andrews et al Elife. 2019 Jan 22;8. pii: 43322. doi: 1
    Insert
    anti-LRRK2/Dardarin, N-terminus (Homo sapiens) recombinant mouse monoclonal antibody (LRRK2 Mouse)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Dual CMV
    Available since
    June 1, 2022
    Availability
    Academic Institutions and Nonprofits only
    182104-plasmid-map-sequence-id-363149

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  9. pLV-Hygro-EF1a-XRCC1-EGFP-T2A-Myc-POLB(D256A/PAMmut)

    Plasmid
    #176141
    Purpose
    EGFP fused to the C-terminus of XRCC1, linked by T2A to N-terminus Myc-tagged POLB with the mutation Asp256Ala, a mutation in the PAM site used by POLBKO gRNA1 & a hygromycin resistance cassette
    Depositor
    Robert Sobol
    Article
    Koczor et al Cell Rep. 2021 Nov 2;37(5):109917. doi:
    Insert
    XRCC1-T2A-PolB (XRCC1, POLB Human)
    Use
    Lentiviral
    Tags
    EGFP and MYC
    Expression
    Mammalian
    Mutation
    Myc-tagged PolB with mutation in Asp256 to Ala, a…
    Promoter
    EF1A
    Available since
    Jan. 26, 2022
    Availability
    Academic Institutions and Nonprofits only
    176141-plasmid-map-sequence-id-353041

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  10. pLV-Hygro-EF1a-XRCC1-EGFP-T2A-Myc-POLB(K35A/K68A/K72/PAMmut)

    Plasmid
    #176140
    Purpose
    EGFP fused to the C-terminus of XRCC1, linked by T2A to N-terminus Myc-tagged POLB with the mutations Lys35Ala, Lys68Ala, Lys72Ala, a mutation in the PAM site used by POLBKO gRNA1 & a hygromycin resis
    Depositor
    Robert Sobol
    Article
    Koczor et al Cell Rep. 2021 Nov 2;37(5):109917. doi:
    Insert
    XRCC1-T2A-PolB (XRCC1, POLB Human)
    Use
    Lentiviral
    Tags
    EGFP and MYC
    Expression
    Mammalian
    Mutation
    Myc-tagged PolB with mutations Lys35 to Ala, Lys6…
    Promoter
    EF1A
    Available since
    Jan. 26, 2022
    Availability
    Academic Institutions and Nonprofits only
    176140-plasmid-map-sequence-id-353035

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  14. pT3-EF1A-MYC-IRES-lucOS

    Plasmid
    #129776
    Purpose
    Transposon based vector that expresses human MYC followed by IRES and firefly luciferase and the antigens SIYRYYGL (SIY), SIINFEKL (SIN, OVA257-264), and OVA323-339
    Depositor
    Amaia Lujambio
    Article
    Ruiz de Galarreta et al Cancer Discov. 2019 Jun 11. pii: 2159-82
    Insert
    human MYC (MYC Human)
    Use
    Tags
    OS: SIYRYYGL (SIY), SIINFEKL (SIN, OVA257-264), a…
    Expression
    Mammalian
    Mutation
    Promoter
    EF1A
    Available since
    Feb. 13, 2020
    Availability
    Academic Institutions and Nonprofits only
    129776-plasmid-map-sequence-id-263368

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  17. pCDNA3-Flag-SPRTN-E112A

    Plasmid
    #110215
    Purpose
    Expression in mammalian cells of of full-length SPRTN protein carrying E112A mutation, a catalytically-dead mutant, and Flag-tag at N-terminus.
    Depositor
    Ivana Marinovic-Terzic, Kristijan Ramadan
    Article
    Lessel et al Nat Genet. 2014 Nov;46(11):1239-44. doi:
    Insert
    SPRTN (SPRTN Human)
    Use
    Tags
    Flag
    Expression
    Mammalian
    Mutation
    E112A, P296L (see depositor comments below)
    Promoter
    Available since
    May 23, 2018
    Availability
    Academic Institutions and Nonprofits only
    110215-plasmid-map-sequence-id-210950

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  21. pDRM56 tet-AR(1-707)C617Y

    Plasmid
    #183504
    Purpose
    Lentiviral vector expressing a doxycycline-inducible truncated DNA-binding mutant androgen receptor (AR mutant C617Y)
    Depositor
    Wayne Tilley
    Article
    Hickey et al Nat Med. 2021 Feb;27(2):310-320. doi: 10
    Insert
    Androgen receptor (AR Human)
    Use
    Lentiviral
    Tags
    Expression
    Mammalian
    Mutation
    Truncated mutant AR; spans AR 1-707 aa, and conta…
    Promoter
    CMV
    Available since
    May 24, 2022
    Availability
    Academic Institutions and Nonprofits only
    183504-plasmid-map-sequence-id-362518

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  22. pAAV_hSyn-SIO-stChrimsonR-EGFP-P2A-PdCO-miniWPRE

    Plasmid
    #202199
    Purpose
    Expresses bicistronically soma-targeted ChrimsonR in frame with EGFP and the optimized PdCO under control of human synapsin1 promotor after Cre-dependent recombination
    Depositor
    Ofer Yizhar
    Article
    Wietek et al Nat Methods. 2024 May 29. doi: 10.1038/s
    Has Service
    AAV1 and AAV5
    Insert
    stChrimsonR, PdCO
    Use
    AAV and Cre/Lox
    Tags
    EGFP and Rho1D4
    Expression
    Mammalian
    Mutation
    Promoter
    hSyn1
    Available since
    July 5, 2023
    Availability
    Academic Institutions and Nonprofits only
    202199-plasmid-map-sequence-id-397078

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  25. pAAV-CamKIIa(0.4)-stChrimsonR-EGFP-P2A-PdCO-WPRE

    Plasmid
    #202198
    Purpose
    Expresses bicistronically soma-targeted ChrimsonR in frame with EGFP and the optimized PdCO under control of minimal CamKIIa promotor
    Depositor
    Ofer Yizhar
    Article
    Wietek et al Nat Methods. 2024 May 29. doi: 10.1038/s
    Insert
    stChrimsonR, PdCO
    Use
    AAV
    Tags
    EGFP and Rho1D4
    Expression
    Mammalian
    Mutation
    Promoter
    CaMKIIα minimal promotor (0.4kb)
    Available since
    July 5, 2023
    Availability
    Academic Institutions and Nonprofits only
    202198-plasmid-map-sequence-id-397077

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Showing: 3401 - 3450 of 3976 results