Purpose
Delivery of human-codon-optimized Cas9 from Neisseria meningitidis (NmeCas9) and its single-guide RNA in a single AAV vector for in vivo genome editing.
Inserts
sgRNA scaffold
Human-codon-optimized NmeCas9
Use
AAV, CRISPR, and Mouse Targeting
Tags
Expression
Mammalian
Mutation
Available since
Aug. 13, 2018
Availability
Academic Institutions and Nonprofits only