1,555 results

1. pPU-HSA-miR30-L1221

   Plasmid

   #174221

   Purpose

   All-in-one control rescue-control shRNA knockdown vector

   Depositor

   Jeremy Luban

   Article

   Guney et al Proc Natl Acad Sci U S A. 2024 Jul 16;12

   Insert

   HSA
   

   Use

   Lentiviral and RNAi

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   SFFV

   Available since

   Aug. 27, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pPU-HSA-miR30-MDA5

   Plasmid

   #174222

   Purpose

   All-in-one control rescue-MDA5 shRNA knockdown vector

   Depositor

   Jeremy Luban

   Article

   Guney et al Proc Natl Acad Sci U S A. 2024 Jul 16;12

   Insert

   HSA
   

   Use

   Lentiviral and RNAi

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   SFFV

   Available since

   Aug. 27, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pPU-huMDA5-miR30-L1221

   Plasmid

   #174223

   Purpose

   All-in-one huMDA5 rescue-control shRNA knockdown vector

   Depositor

   Jeremy Luban

   Article

   Guney et al Proc Natl Acad Sci U S A. 2024 Jul 16;12

   Insert

   MDA5 (IFIH1 Human)
   

   Use

   Lentiviral and RNAi

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   SFFV

   Available since

   Aug. 27, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pTFG002-ACE2(Mut)-HA

   Plasmid

   #191570

   Purpose

   ACE2 insert in a 2nd generation lentiviral transfer plasmid (pGIPZ) to generate ACE2(Mut)-expressing cells. Codon-optimized for human expression. Insert contains C-terminal HA Tag.

   Depositor

   Joshua Leonard

   Article

   Gunnels et al Small. 2022 May;18(19):e2200125. doi: 10

   Insert

   Angiotensin Converting Enzyme II (ACE2 Human)
   

   Use

   Lentiviral and RNAi

   Tags

   HA tag

   Expression

   Mammalian

   Mutation

   Codon-optimized for human expression. Also contai…

   Promoter

   CMV

   Available since

   Aug. 5, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pTFG001-ACE2(WT)-HA

   Plasmid

   #191569

   Purpose

   ACE2 insert in a 2nd generation lentiviral transfer plasmid (pGIPZ) to generate ACE2(WT)-expressing cells. Codon-optimized for human expression. Insert contains C-terminal HA tag.

   Depositor

   Joshua Leonard

   Article

   Gunnels et al Small. 2022 May;18(19):e2200125. doi: 10

   Insert

   Angiotensin Converting Enzyme II (ACE2 Human)
   

   Use

   Lentiviral and RNAi

   Tags

   HA tag

   Expression

   Mammalian

   Mutation

   Codon optimized for expression in human cells

   Promoter

   CMV

   Available since

   Aug. 5, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pLKO.1 mTagBFP2 rat DJ-1 shRNA

   Plasmid

   #222870

   Purpose

   Expresses mTagBFP2 along with an shRNA against rat DJ-1

   Depositor

   Timothy Ryan

   Article

   Kokotos et al Sci Adv. 2024 Aug 23;10(34):eadn6016. do

   Insert

   DJ-1 shRNA (Park7 Rat)
   

   Use

   Lentiviral and RNAi

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   July 9, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pgRNA-bacteria_speG_M15

   Plasmid

   #220488

   Purpose

   inducible CRISPRi

   Depositor

   Emily Balskus

   Article

   Mayers et al Cell. 2024 Jun 11:S0092-8674(24)00579-8.

   Insert

   gspeG
   

   Use

   CRISPR and RNAi

   Tags

   Expression

   Mutation

   none

   Promoter

   Available since

   June 26, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pgRNA-bacteria_speG_E23

   Plasmid

   #220489

   Purpose

   inducible CRISPRi

   Depositor

   Emily Balskus

   Article

   Mayers et al Cell. 2024 Jun 11:S0092-8674(24)00579-8.

   Insert

   gspeG
   

   Use

   CRISPR and RNAi

   Tags

   Expression

   Mutation

   none

   Promoter

   Available since

   June 26, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pXPR_003.gEZH2

   Plasmid

   #220318

   Purpose

   Expresses guide RNA for CRISPR/Cas9 knockout of EZH2 for knockout/rescue experiments in mammalian cells.

   Depositor

   Chen Davidovich

   Article

   Gail et al Nat Genet. 2024 May 14. doi: 10.1038/s41

   Insert

   EZH2 gRNA (EZH2 Human)
   

   Use

   Lentiviral and RNAi

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   June 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pTRIPZ-shWT1_A

    Plasmid

    #217636

    Purpose

    Dox inducible shRNA targeting WT-1

    Depositor

    Constanze Bonifer

    Article

    Potluri et al Cell Rep. 2021 Apr 20;35(3):109010. doi:

    Insert

    shWT1_A (WT1 Human)
    

    Use

    RNAi

    Tags

    Expression

    Mutation

    Promoter

    Available since

    May 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pTRIPZ-shWT1_B

    Plasmid

    #217637

    Purpose

    Dox inducible shRNA targeting WT-1

    Depositor

    Constanze Bonifer

    Article

    Potluri et al Cell Rep. 2021 Apr 20;35(3):109010. doi:

    Insert

    shWT1_B (WT1 Human)
    

    Use

    RNAi

    Tags

    Expression

    Mutation

    Promoter

    Available since

    May 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pUN381 - pTRV2-CHLH

    Plasmid

    #203886

    Purpose

    Viral silencing plasmid targeting the CHLH gene from C. roseus. For use as a positive control for VIGS experiments.

    Depositor

    Carolyn Lee-Parsons

    Article

    Cole-Osborn et al Plant Cell Rep. 2024 May 14;43(6):141. d

    Insert

    CHLH fragment
    

    Use

    RNAi

    Tags

    Expression

    Plant

    Mutation

    Promoter

    Available since

    April 26, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. pUN378 - pTRV2-CrGLK

    Plasmid

    #203888

    Purpose

    Viral silencing plasmid targeting the CrGLK gene from C. roseus.

    Depositor

    Carolyn Lee-Parsons

    Article

    Cole-Osborn et al Plant Cell Rep. 2024 May 14;43(6):141. d

    Insert

    CrGLK fragment
    

    Use

    RNAi

    Tags

    Expression

    Plant

    Mutation

    Promoter

    Available since

    April 26, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. rSirt3 shRNA (pLKO.1 vector)

    Plasmid

    #216807

    Purpose

    shRNA against rat Sirt3

    Depositor

    Ghazaleh Ashrafi

    Article

    Tiwari et al J Cell Biol. 2024 Jan 1;223(1):e20230504

    Insert

    Sirt3 (Sirt3 Rat)
    

    Use

    Lentiviral and RNAi

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    April 10, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. shTRIP13-2-seed

    Plasmid

    #184535

    Purpose

    shRNA expression vector

    Depositor

    Andrew Hong

    Article

    Mittal et al Commun Biol. 2024 Apr 8;7(1):426. doi: 1

    Insert

    TRIP13 (TRIP13 Human)
    

    Use

    RNAi

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    April 8, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. shTRIP13-1

    Plasmid

    #184536

    Purpose

    shRNA expression vector

    Depositor

    Andrew Hong

    Article

    Mittal et al Commun Biol. 2024 Apr 8;7(1):426. doi: 1

    Insert

    TRIP13 (TRIP13 Human)
    

    Use

    RNAi

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    April 8, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. shTRIP13-2

    Plasmid

    #184537

    Purpose

    shRNA expression vector

    Depositor

    Andrew Hong

    Article

    Mittal et al Commun Biol. 2024 Apr 8;7(1):426. doi: 1

    Insert

    TRIP13 (TRIP13 Human)
    

    Use

    RNAi

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    April 8, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pUC-hU6-shBACH1_BFP

    Plasmid

    #199217

    Purpose

    Expression plasmid with shRNAmiR targeting BACH1, with a BFP reporter on the backbone. 

    Depositor

    Gabor Balazsi

    Article

    Wan et al Nat Chem Biol. 2023 Jul;19(7):887-899. d

    Insert

    shBACH1 (BACH1 Synthetic)
    

    Use

    RNAi

    Tags

    Expression

    Mutation

    Promoter

    human U6

    Available since

    Aug. 2, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. UBE2G2 shRNA

    Plasmid

    #201813

    Purpose

    siRNA

    Depositor

    Allan Weissman

    Article

    Chen et al Proc Natl Acad Sci U S A. 2006 Jan 10. 1

    Insert

    UBE2G2 (UBE2G2 Human)
    

    Use

    RNAi

    Tags

    Expression

    Mutation

    Promoter

    Available since

    July 5, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pUC_hU6-shRKIP_BFP

    Plasmid

    #199216

    Purpose

    Expression plasmid with shRNAmiR targeting RKIP (PEBP1), with a BFP reporter on the backbone.

    Depositor

    Gabor Balazsi

    Article

    Wan et al Nat Chem Biol. 2023 Jul;19(7):887-899. d

    Insert

    shBACH1 (BACH1 Synthetic)
    

    Use

    RNAi

    Tags

    Expression

    Mutation

    Promoter

    human U6

    Available since

    June 28, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge