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ATR gRNA (BRDN0001145195)

Plasmid

#77550

Purpose

3rd generation lentiviral gRNA plasmid targeting human ATR

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ATR (ATR Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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SIN-cPPT-H1-sgHTT1-PGK-mCherry-WPRE

Plasmid

#87885

Purpose

To produce lentiviral vector for HTT editing

Depositor

Nicole Déglon

Article

Merienne et al Cell Rep. 2017 Sep 19;20(12):2980-2991.

Insert

shHTT1, cherry

Use

Lentiviral

Tags

Expression

Mutation

Promoter

H1, PGK

Available since

Sept. 19, 2017

Availability

Academic Institutions and Nonprofits only

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IGF1R gRNA (BRDN0001148211)

Plasmid

#76690

Purpose

3rd generation lentiviral gRNA plasmid targeting human IGF1R

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

IGF1R (IGF1R Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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nSR100L4

Plasmid

#35174

Depositor

Benjamin Blencowe

Article

Calarco et al Cell. 2009 Sep 4;138(5):898-910.

Insert

MmnSR100

Use

Lentiviral and RNAi

Tags

Expression

Mammalian

Mutation

Promoter

U6

Available since

March 30, 2012

Availability

Academic Institutions and Nonprofits only
pCLXEBR-pTF-Ngn3

Plasmid

#114307

Purpose

TET-inducible expression of the Neugenin 3 transcription factor

Depositor

Patrick Salmon

Article

Giry-Laterriere et al Hum Gene Ther. 2011 Oct;22(10):1255-67.

Insert

Ngn3 (NEUROG3 Human)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

Sept. 11, 2018

Availability

Academic Institutions and Nonprofits only

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RIPK3 gRNA (BRDN0001147505)

Plasmid

#76996

Purpose

3rd generation lentiviral gRNA plasmid targeting human RIPK3

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

RIPK3 (RIPK3 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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RIPK3 gRNA (BRDN0001145972)

Plasmid

#76997

Purpose

3rd generation lentiviral gRNA plasmid targeting human RIPK3

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

RIPK3 (RIPK3 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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RIPK3 gRNA (BRDN0001145339)

Plasmid

#76998

Purpose

3rd generation lentiviral gRNA plasmid targeting human RIPK3

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

RIPK3 (RIPK3 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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pFIN-RK-GFP-mIRBP156-CHER-WPRE

Plasmid

#44351

Depositor

Susan Semple-Rowland

Article

Semple-Rowland et al Mol Vis. 2010 May 27;16:916-34.

Inserts

RK-GFP
mIRBP156-CHER

Use

Lentiviral

Tags

Expression

Mutation

Promoter

human rhodopsin kinase (pos 2554-2850) and mouse …

Available since

May 8, 2013

Availability

Academic Institutions and Nonprofits only

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FgH1tUTG_Bfl-1.1

Plasmid

#85536

Purpose

Inducible expression of guide RNA (Bfl-1.1) with fluorescent GFP reporter

Depositor

Marco Herold

Insert

Bfl1.1

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

H1t

Available since

Jan. 25, 2017

Availability

Academic Institutions and Nonprofits only

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pLKO.1-Blast-cfCdc42_3

Plasmid

#26704

Depositor

Keith Mostov

Article

Bryant et al Nat Cell Biol. 2010 Oct 3. ():.

Insert

Dog Cdc42 RNAi

Use

Lentiviral and RNAi

Tags

Expression

Mammalian

Mutation

Dog Cdc42 RNAi

Promoter

Available since

Dec. 15, 2010

Availability

Academic Institutions and Nonprofits only
UGPC

Plasmid

#138954

Purpose

Lentiviral vector for co-expressing Cre recombinase and sgRNA

Depositor

Nadya Dimitrova

Article

Olivero et al Mol Cell. 2020 Feb 20;77(4):761-774.e8.

Type

Empty backbone

Use

Cre/Lox and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

U6 and PGK

Available since

Aug. 28, 2020

Availability

Academic Institutions and Nonprofits only

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PKD1 gRNA (BRDN0001149544)

Plasmid

#76841

Purpose

3rd generation lentiviral gRNA plasmid targeting human PKD1

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PKD1 (PKD1 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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LZF40: LZF40_Fsyn_Cre

Plasmid

#109378

Purpose

Synaptic transmission

Depositor

Adam Cohen

Article

Adam et al Nature. 2019 May 1. pii: 10.1038/s41586-

Insert

Cre-NCBI

Use

Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

human synapsin I

Available since

May 2, 2019

Availability

Academic Institutions and Nonprofits only

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pLV-tetO-Tpbpa

Plasmid

#70698

Purpose

Lentiviral plasmid for tetracycline/doxycycline dependent expression of murine Tpbpa

Depositor

Hubert Schorle

Article

Kubaczka et al Cell Stem Cell. 2015 Sep 22. pii: S1934-

Insert

Trophoblast specific protein alpha (Tpbpa Mouse)

Use

Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

tetO

Available since

Nov. 16, 2015

Availability

Academic Institutions and Nonprofits only
PRKCI gRNA (BRDN0001148989)

Plasmid

#76401

Purpose

3rd generation lentiviral gRNA plasmid targeting human PRKCI

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PRKCI (PRKCI Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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KDR gRNA (BRDN0001146819)

Plasmid

#77755

Purpose

3rd generation lentiviral gRNA plasmid targeting human KDR

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

KDR (KDR Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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KDR gRNA (BRDN0001146648)

Plasmid

#77756

Purpose

3rd generation lentiviral gRNA plasmid targeting human KDR

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

KDR (KDR Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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KDR gRNA (BRDN0001144938)

Plasmid

#77757

Purpose

3rd generation lentiviral gRNA plasmid targeting human KDR

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

KDR (KDR Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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FLT1 gRNA (BRDN0001145564)

Plasmid

#75557

Purpose

3rd generation lentiviral gRNA plasmid targeting human FLT1

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

FLT1 (FLT1 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge