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pJC112.4-spp-7

Plasmid

#26511

Depositor

Phillip Newmark

Article

Collins et al PLoS Biol. 2010 . 8(10):e1000509.

Insert

spp-7

Use

RNAi

Tags

Expression

Mutation

Promoter

Available since

Oct. 29, 2010

Availability

Academic Institutions and Nonprofits only
pGC452

Plasmid

#19627

Depositor

Jane Hubbard

Article

Voutev et al Genetics. 2008 Sep;180(1):103-19. doi: 1

Insert

Phlh-12

Use

RNAi; Flp/frt

Tags

Expression

Worm

Mutation

Promoter

Available since

March 16, 2009

Availability

Academic Institutions and Nonprofits only

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frh-1-A

Plasmid

#15399

Depositor

Michael Ristow

Article

Zarse et al FASEB J. 2007 Apr . 21(4):1271-5.

Insert

Frataxin homologue (frh-1 Nematode)

Use

RNAi

Tags

Expression

Mutation

Promoter

Available since

Aug. 17, 2007

Availability

Academic Institutions and Nonprofits only

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frh-1-C

Plasmid

#15401

Depositor

Michael Ristow

Article

Zarse et al FASEB J. 2007 Apr . 21(4):1271-5.

Insert

Frataxin homologue (frh-1 Nematode)

Use

RNAi

Tags

Expression

Mutation

Promoter

Available since

Aug. 17, 2007

Availability

Academic Institutions and Nonprofits only

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pJMP2046

Plasmid

#160073

Purpose

Z. mobilis CRISPRi, promoter A, empty guide, sfGFP

Depositor

Jason Peters

Article

Banta et al Appl Environ Microbiol. 2020 Nov 10;86(2

Insert

empty sgRNA

Use

Tags

Expression

Bacterial

Mutation

Promoter

Available since

Availability

Academic Institutions and Nonprofits only

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Multiplex-CRISPR-miR-200FAM-T2A-GFP

Plasmid

#179856

Purpose

to delete miR200 family genes including miR-141, miR-200c, miR-429 and miR-200b

Depositor

Brendan Jenkins

Article

Yu et al Oncogene. 2021 Oct 19. pii: 10.1038/s413

Insert

hsa-miR-200 family (miR-200b, miR-200a, miR-429, miR-141 and miR-200c ) (MIR141, MIR200B, MIR429, MIR200C, MIR200A Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

Available since

March 22, 2022

Availability

Academic Institutions and Nonprofits only

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pAAV-rMERTK-HITI

Plasmid

#87119

Purpose

Gene correction donor AAV for RCS rat. AAV backbone plasmid including exon 2 of rat Mertk and rMertkgRNA for HITI

Depositor

Juan Belmonte

Article

Suzuki et al Nature. 2016 Dec 1;540(7631):144-149. do

Insert

U6-rMertksgRNA-Mertk(intron1-2)-nEF-GFPKASH-pA

Use

AAV and CRISPR

Tags

Expression

Mutation

Promoter

Available since

March 22, 2017

Availability

Academic Institutions and Nonprofits only

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pXPR_BRD003 PSMB5 guide 1

Plasmid

#117073

Purpose

single guide RNA targeting PSMB5; guide 1

Depositor

William Hahn

Article

Hong et al Elife. 2019 Mar 12;8. pii: 44161. doi: 1

Insert

LMPX (PSMB5 Human)

Use

CRISPR

Tags

Expression

Mutation

Promoter

hU6

Available since

March 13, 2019

Availability

Academic Institutions and Nonprofits only

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pXPR_BRD003-sgWRN1

Plasmid

#125771

Purpose

constitutive expression of a guide RNA targeting human WRN

Depositor

Francisca Vazquez

Article

Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

Insert

sgWRN1 (WRN Human)

Use

CRISPR

Tags

Expression

Mutation

Promoter

Available since

June 4, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pXPR_BRD003-sgWRN-EIJ

Plasmid

#125774

Purpose

constitutive expression of a guide RNA targeting an exon-intron junction of human WRN

Depositor

Francisca Vazquez

Article

Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

Insert

sgWRN-EIJ (WRN Human)

Use

CRISPR

Tags

Expression

Mutation

Promoter

Available since

June 11, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pXPR_BRD051-sgCh2-2

Plasmid

#125775

Purpose

constitutive expression of a guide RNA targeting an intergenic region of human chromosome 2 (CRISPR cutting control) and S. pyogenes Cas9

Depositor

Francisca Vazquez

Article

Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

Insert

sgCh2-2

Use

CRISPR

Tags

Expression

Mutation

Promoter

Available since

June 4, 2019

Availability

Academic Institutions and Nonprofits only

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pXPR_BRD003-sgWRN2

Plasmid

#125772

Purpose

constitutive expression of a guide RNA targeting human WRN

Depositor

Francisca Vazquez

Article

Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

Insert

sgWRN2 (WRN Human)

Use

CRISPR

Tags

Expression

Mutation

Promoter

Available since

May 29, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pXPR_BRD003-sgPOLR2D

Plasmid

#125769

Purpose

constitutive expression of a guide RNA targeting human POLR2D (CRISPR positive control)

Depositor

Francisca Vazquez

Article

Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

Insert

sgPOLR2D (POLR2D Human)

Use

CRISPR

Tags

Expression

Mutation

Promoter

Available since

May 29, 2019

Availability

Academic Institutions and Nonprofits only

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pXPR_BRD003 PSMB5 guide 2

Plasmid

#117074

Purpose

single guide RNA targeting PSMB5; guide 2

Depositor

William Hahn

Article

Hong et al Elife. 2019 Mar 12;8. pii: 44161. doi: 1

Insert

LMPX (PSMB5 Human)

Use

CRISPR

Tags

Expression

Mutation

Promoter

hU6

Available since

March 13, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pXPR_BRD003-sgWRN3

Plasmid

#125773

Purpose

constitutive expression of a guide RNA targeting human WRN

Depositor

Francisca Vazquez

Article

Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

Insert

sgWRN3 (WRN Human)

Use

CRISPR

Tags

Expression

Mutation

Promoter

Available since

June 11, 2019

Availability

Academic Institutions and Nonprofits only

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pAAV-Ai14-luc

Plasmid

#87118

Purpose

AAV backbone plasmid including luc-pA knock-in donor and Ai14gRNA for HITI

Depositor

Juan Belmonte

Article

Suzuki et al Nature. 2016 Dec 1;540(7631):144-149. do

Insert

U6-Ai14sgRNA-Luciferase-nEF-GFPKASH-hGHpA

Use

AAV, CRISPR, and Luciferase

Tags

Expression

Mutation

Promoter

Available since

March 30, 2017

Availability

Academic Institutions and Nonprofits only

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pXPR_BRD003-sgCh2-2

Plasmid

#125767

Purpose

constitutive expression of a guide RNA targeting an intergenic region of human chromosome 2 (CRISPR cutting control)

Depositor

Francisca Vazquez

Article

Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

Insert

sgCh2-2

Use

CRISPR

Tags

Expression

Mutation

Promoter

Available since

June 4, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pXPR_BRD003-sgCh2-4

Plasmid

#125768

Purpose

constitutive expression of a guide RNA targeting an intergenic region of human chromosome 2 (CRISPR cutting control)

Depositor

Francisca Vazquez

Article

Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

Insert

sgCh2-4

Use

CRISPR

Tags

Expression

Mutation

Promoter

Available since

June 4, 2019

Availability

Academic Institutions and Nonprofits only

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pXPR_BRD003 UBE2C guide 1

Plasmid

#117068

Purpose

single guide RNA targeting UBE2C; guide 1

Depositor

William Hahn

Article

Hong et al Elife. 2019 Mar 12;8. pii: 44161. doi: 1

Insert

UBCH10 (UBE2C Human)

Use

CRISPR

Tags

Expression

Mutation

Promoter

hU6

Available since

March 13, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pXPR_BRD003 UBE2C guide 2

Plasmid

#117071

Purpose

single guide RNA targeting UBE2C; guide 2

Depositor

William Hahn

Article

Hong et al Elife. 2019 Mar 12;8. pii: 44161. doi: 1

Insert

UBCH10 (UBE2C Human)

Use

CRISPR

Tags

Expression

Mutation

Promoter

Available since

March 13, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge